The role of platelet-rich plasma in biomedicine: A comprehensive overview by Zhixin Zhang, Peng Liu, Xinmiao Xue, Zhiyu Zhang, Li Wang, Yvke Jiang, Chi Zhang, Hanwen Zhou, Shuhan Lv, Weidong Shen, Shiming Yang, Fangyuan Wang

“…Summary: Biomedicine has seen significant advancements in the 21st century, with platelet-rich plasma (PRP) playing a crucial role in clinical practice. This blood derivative, enriched with platelet components, has shown great potential for promoting tissue repair and regeneration. …”
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Prediction model for type 2 diabetes mellitus and its association with mortality using machine learning in three independent cohorts from South Korea, Japan, and the UK: a model de... by Hayeon Lee, Seung Ha Hwang, Seoyoung Park, Yunjeong Choi, Sooji Lee, Jaeyu Park, Yejun Son, Hyeon Jin Kim, Soeun Kim, Jiyeon Oh, Lee Smith, Damiano Pizzol, Sang Youl Rhee, Hyunji Sang, Jinseok Lee, Dong Keon Yon

“…The SHAP value analysis of our proposed model revealed that age was the most important predictor of incident T2DM, followed by fasting blood glucose, hemoglobin, γ-glutamyl transferase level, and body mass index. …”
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Protocol and statistical analysis plan for the PREventing cardiovascular collaPse with Administration of fluid REsuscitation during Induction and Intubation (PREPARE II) randomised... by Li Wang, Tamer Hudali, Shekhar Ghamande, Megan Moore, Bruno Pereira, Christopher J Lindsell, Wesley H Self, Todd W Rice, Matthew W Semler, Kate O’Connor, David B Page, Victor E Ortega, Aaron M Joffe, Swati Gulati, G Patel, Heath D White, Muhammad Ali, Jonathan D Casey, David R Janz, Derek W Russell, Derek J Vonderhaar, Kevin M Dischert, William S Stigler, Emily Adams, Kevin W Gibbs, James M Dargin, A M Joffe, Akram Khan, Simanta Dutta, Janna S Landsperger, Sarah W Robison, Itay Bentov, Joanne M Wozniak, Susan Stempek, Olivia F Krol, Matthew E Prekker, Brian E Driver, Joseph M Brewer, Christopher John Lindsell, David Janz, Stephen P Peters, Rita N Bakhru, Scott Bauer, Christina R Bellinger, Amanda M Brown, Blair Brown, Jerri Brown, Caitlin Bumgarner, Wendy Butcher, Megan Caudle, Arjun B Chatterjee, David J Chodos, Gerardo Corcino, Nathan S Cutler, Travis L Dotson, Daniel C Files, Jonathan L Forbes, John P Gaillard, Katherine A Gershner, Shannon Ginty, Kiadrick R Hood, April Hazelwood, Katherine Hendricks, Kelly Jacobus, Jonathan T Jaffe, Stacy Kay, Chad A Kloefkorn, Jennifer Krall, Margo T Lannan, Cornelia Lane, Cynthia Lanning, Jessica Lyons, William I Mariencheck, Chad R Marion, Matthew A Maslonka, Sara McClintock, Nathaniel M Meier, Matthew C Miles, Peter J Miller, Sophia Mitchell, Wendy C Moore, Katherine Moss, Andrew M Namen, Dustin L Norton, Stella B Ogake, Jill A Ohar, Jessica A Palakshappa, Rodolfo M Pascual, Sandi Pascual, Aaron Pickens, Adam R Schertz, Matt Strong, Alexander O Sy, Braghadheeswar Thyagarajan, Amy Townsend, Russell Worthen, Michael Wlodarski, Charles Yarbrough, Caroline York, Bradley Lloyd, James Dargin, Joanne Wozniak, Christopher Adler, Ahmed Agameya, Michael Colancecco, Daniel Fitelson, Joshua Giaccotto, Gena Han, Louise Kane, Ezra Miller, Timothy Noland, Jaqueline Price, Joseph Plourde, Fraser Mackay, Laura Mahoney, Avignat Patel, Michael Plourde, Zena Saadeh, Sara Shadchehr, Sandeep Somalaraju, Eleanor Summerhill, Ryan Webster, Jordan Winnicki, Ekaterina Yavarovich, Sheetal Gandotra, Anna Altz-Stamm, Cristina Bardita, Mary Clay Boone, Joe W Chiles, Kristina Collins, Abby Drescher, Kevin G Dsouza, Janna Dunn, Stacy Ejem, Josh Gautney, Nicole Harris, Savannah Herder, R Chad Wade, Rutwij Joshi, Daniel Kelmenson, Anne Merrill Mason, Scott R Merriman, Takudzwa Mkorombindo, Jada Nowak, D Sheylan, Lisa Sarratt, Tabitha Stewart, Kadambari Vijaykumar, Gina White, Micah R Whitson, Christopher Barnes, Andrew M Walters, Alejandro C Arroliga, Tasnim Lat, Stephanie Nonas, Milad K Jouzestani, Raya Adi, Chandani Anandkat, Hanae Benchbani, Matthew G Drake, Makrina N Kamel, Ramanpreet Randhawa, Jessica L Tsui

“…The primary outcome is cardiovascular collapse, defined as any of: systolic blood pressure <65 mm Hg, new or increased vasopressor administration between induction and 2 min after intubation, or cardiac arrest or death between induction and 1 hour after intubation. …”
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Uptake and 4-week outcomes of an ‘opt-out’ smoking cessation referral strategy in a London-based lung cancer screening setting by Anthony Edey, Neal Navani, Kitty Chan, Graham Robinson, Janine Zylstra, Paul Robinson, Laura Green, Anand Devaraj, Jane Rowlands, Allan Hackshaw, Carolyn Horst, Arjun Nair, Sam M Janes, Kate Davies, Jeannie Eng, Mamta Ruparel, Samantha L Quaife, Jennifer L Dickson, Magali Taylor, Angshu Bhowmik, Hasti Robbie, Joseph Jacob, Laura Farrelly, Sophie Tisi, Tanya Patrick, Andrew Creamer, Helen Hall, Samanjit Hare, Jon Teague, Samuel M Janes, Esther Arthur-Darkwa, Thea Buchan, Stephen Ellis, Thomas Callender, Rachael Sarpong, John McCabe, Zaheer Mangera, Ethaar El-Emir, Terry O'Shaughnessy, Geoff Bellingan, Nick Screaton, Priyam Verghese, William M Ricketts, Vicky Bowyer, Kylie Gyertson, Fanta Bojang, Claire Levermore, Tania Anastasiadis, Ruth Prendecki, Amyn Bhamani, Malavika Suresh, Judy Airebamen, Alice Cotton, Kaylene Phua, Elodie Murali, Simranjit Mehta, Karen Parry-Billings, Columbus Ife, April Neville, Zahra Hanif, Helen Kiconco, Ricardo McEwen, Dominique Arancon, Nicholas Beech, Derya Ovayolu, Christine Hosein, Sylvia Patricia Enes, Qin April Neville, Aashna Samson, Urja Patel, Fahmida Hoque, Hina Pervez, Sofia Nnorom, Moksud Miah, Julian McKee, Mark Clark, Anant Patel, Sara Lock, Rajesh Banka, Ugo Ekeowa, Charlotte Cash, Tunku Aziz, Alberto Villanueva, Elena Stefan, Charlie Sayer, Navinah Nundlall, Andrew Crossingham, Tanita Limani, Kate Gowers, Andrew Perugia, James Rusius, Anne-Marie Hacker, Monica L Mullin, Evangelos Katsampouris, Chuen R Khaw, Chuen Khaw, Sheetal Karavadra, Alan Shaw, Chris Valerio, Ali Mohammed, Lynsey Gallagher, Mehran Azimbagirad, Burcu Ozaltin, Maureen Browne, Eleanor Hellier, Catherine Nestor

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Adenomas from individuals with pathogenic biallelic variants in the MUTYH and NTHL1 genes demonstrate base excision repair tumour mutational signature profiles similar to colorecta... by Romy Walker, Jihoon E. Joo, Khalid Mahmood, Mark Clendenning, Julia Como, Susan G. Preston, Sharelle Joseland, Bernard J. Pope, Ana B.D. Medeiros, Brenely V. Murillo, Nicholas Pachter, Kevin Sweet, Allan D. Spigelman, Alexandra Groves, Margaret Gleeson, Krzysztof Bernatowicz, Nicola Poplawski, Lesley Andrews, Emma Healey, Steven Gallinger, Robert C. Grant, Aung K. Win, John L. Hopper, Mark A. Jenkins, Giovana T. Torrezan, Christophe Rosty, Finlay A. Macrae, Ingrid M. Winship, Daniel D. Buchanan, Peter Georgeson

“…Methods: Whole-exome sequencing of FFPE tissue and matched blood-derived DNA was performed on 9 adenomas and 15 CRCs from 13 biallelic MUTYH cases, on 7 adenomas and 2 CRCs from 5 biallelic NTHL1 cases and on 27 adenomas and 26 CRCs from 46 non-hereditary (sporadic) participants. …”
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The 2023 dengue outbreak in Lombardy, Italy: A one-health perspective by Francesca Rovida, Marino Faccini, Carla Molina Granè, Irene Cassaniti, Sabrina Senatore, Eva Rossetti, Giuditta Scardina, Manuela Piazza, Giulia Campanini, Daniele Lilleri, Stefania Paolucci, Guglielmo Ferrari, Antonio Piralla, Francesco Defilippo, Davide Lelli, Ana Moreno, Luigi Vezzosi, Federica Attanasi, Marzia Soresini, Manuela Barozzi, Lorenzo Cerutti, Stefano Paglia, Angelo Regazzetti, Maurilia Marcacci, Guido Di Donato, Marco Farioli, Mattia Manica, Piero Poletti, Antonio Lavazza, Maira Bonini, Stefano Merler, Fausto Baldanti, Danilo Cereda, Antonella Sarasini, Milena Furione, Dalila Mele, Federica Bergami, Josè Camilla Sammartino, Alessandro Ferrari, Greta Romano, Antonino Maria Guglielmo Pitrolo, Maya Carrera, Rita Brugnoli, Nunzia Laini, Francesca Bonalda, Sara Arfani, Giuditta Zamboni, Fanny Delfanti, Piergiuseppe Ferrari, Anxhela Dafa, Antonella Negri, Filippa Parisi, Marcello Tirani, Michela Viscardi, Gabriele Del Castillo, Federica Morani, Francesco Scovenna, Sheila Sansebastian, Manuel Maffeo, Mario Chiari, Enrico Tallarita

“…In addition, DENV-1 infection was diagnosed in 24 symptomatic subjects referred to the local Emergency Room Department for suggestive symptoms and 1 case was identified through blood donation screening. The average generation time was estimated to be 18.3 days (95 % CI: 13.1–23.5 days). …”
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Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti... by Arndt Borkhardt, Nan Qin, Stephen T Keir, Darell D Bigner, Allison Cole, Matthias Wölfl, Viktoria Marquardt, Johanna Theruvath, David Pauck, Daniel Picard, Lena Blümel, Mara Maue, Jasmin Bartl, Ulvi Ahmadov, Maike Langini, Frauke-Dorothee Meyer, Joselyn Cruz-Cruz, Claus M Graef, Till Milde, Olaf Witt, Anat Erdreich-Epstein, Gabriel Leprivier, Ulf Kahlert, Anja Stefanski, Kai Stühler, Julia Hauer, Thomas Beez, Christiane B Knobbe-Thomsen, Ute Fischer, Jörg Felsberg, Finn K Hansen, Rajeev Vibhakar, Sujatha Venkatraman, Samuel H Cheshier, Guido Reifenberger, Thomas Kurz, Marc Remke, Siddhartha Mitra

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LRH‐1/NR5A2 targets mitochondrial dynamics to reprogram type 1 diabetes macrophages and dendritic cells into an immune tolerance phenotype by Nadia Cobo‐Vuilleumier, Silvia Rodríguez‐Fernandez, Livia López‐Noriega, Petra I. Lorenzo, Jaime M. Franco, Christian C. Lachaud, Eugenia Martin Vazquez, Raquel Araujo Legido, Akaitz Dorronsoro, Raul López‐Férnandez‐Sobrino, Beatriz Fernández‐Santos, Carmen Espejo Serrano, Daniel Salas‐Lloret, Nila vanOverbeek, Mireia Ramos‐Rodriguez, Carmen Mateo‐Rodríguez, Lucia Hidalgo, Sandra Marin‐Canas, Rita Nano, Ana I. Arroba, Antonio Campos Caro, Alfred CO Vertegaal, Alejandro Martín‐Montalvo, Franz Martín, Manuel Aguilar‐Diosdado, Lorenzo Piemonti, Lorenzo Pasquali, Roman González Prieto, Maria Isabel García Sánchez, Decio L. Eizirik, Maria Asuncion Martínez‐Brocca, Marta Vives‐Pi, Benoit R. Gauthier

“…The discovery that the pharmacological activation of LRH‐1/NR5A2 can reverse hyperglycaemia in mouse models of T1D by attenuating the autoimmune attack coupled to beta cell survival/regeneration prompted us to investigate whether immune tolerisation could be translated to individuals with T1D by LRH‐1/NR5A2 activation and improve islet survival. Methods Peripheral blood mononuclear cells (PBMCs) were isolated from individuals with and without T1D and derived into various immune cells, including macrophages and dendritic cells. …”
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Progressive systemic inflammation precedes decompensation in compensated cirrhosis by Rubén Sánchez-Aldehuelo, Càndid Villanueva, Joan Genescà, Juan Carlos García-Pagán, Elisa Castillo, José Luis Calleja, Carles Aracil, Rafael Bañares, Luis Téllez, Lorena Paule, Rosa María Morillas, María Poca, Beatriz Peñas, Salvador Augustin, Juan G. Abraldes, Edilmar Alvarado-Tapias, Jaume Bosch, Agustín Albillos

“…Methods: This study is nested within the PREDESCI trial, which investigated non-selective beta-blockers for preventing decompensation in compensated cirrhosis and clinically significant portal hypertension (CSPH: hepatic venous pressure gradient ≥10 mmHg). Blood biomarkers were measured at baseline and at 1 and 2 years in patients who remained compensated and had available samples (n = 164). …”
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The Role of Different Emotional States of Customers on Food Preferences by Mahmood Ghanbari, Kambiz Heidarzadeh Hanzaee, Behnaz Khodayari, Maryam Khalili Araghi

“…An unbalanced diet may promote many chronic diseases such as obesity, diabetes, high cholesterol, high blood pressure, heart disease, and stroke (Konttinen, 2020).Ogundijo et al, (2022) investigated factors affecting food choices and consumer purchasing habits in an English university setting. …”
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Therapeutic plasma exchange accelerates immune cell recovery in severe COVID-19 by Aurelie Guironnet-Paquet, Aurelie Guironnet-Paquet, Hind Hamzeh-Cognasse, Frederic Berard, Fabrice Cognasse, Fabrice Cognasse, Jean Christophe Richard, Hodane Yonis, Mehdi Mezidi, Olivier Desebbe, Bertrand Delannoy, Sophie Demeret, Clemence Marois, Clemence Marois, Clemence Marois, Samir Saheb, Quoc Viet Le, Mathieu Schoeffler, Paul Simon Pugliesi, Sophie Debord, Paul Bastard, Paul Bastard, Paul Bastard, Paul Bastard, Aurélie Cobat, Aurélie Cobat, Aurélie Cobat, Jean Laurent Casanova, Jean Laurent Casanova, Jean Laurent Casanova, Jean Laurent Casanova, Jean Laurent Casanova, Rémi Pescarmona, Sébastien Viel, Jean François Nicolas, Jean François Nicolas, Audrey Nosbaum, Audrey Nosbaum, Marc Vocanson, Olivier Hequet, Olivier Hequet

“…BackgroundImmunological disturbances (anti-type I IFN auto-antibody production, cytokine storm, lymphopenia, T-cell hyperactivation and exhaustion) are responsible for disease exacerbation during severe COVID-19 infections.MethodsIn this study, we set up a prospective, randomised clinical trial (ClinicalTrials.gov ID: NCT04751643) and performed therapeutic plasma exchange (TPE) in severe COVID-19 patients in order to decrease excess cytokines and auto-antibodies and to assess whether adding TPE to the standard treatment (ST, including corticosteroids plus high-flow rate oxygen) could help restore immune parameters and limit the progression of acute respiratory distress syndrome (ARDS).ResultsAs expected, performing TPE decreased the amount of anti-type I IFN auto-antibodies and improved the elimination or limited the production of certain inflammatory mediators (IL-18, IL-7, CCL2, CCL3, etc.) circulating in the blood of COVID-19 patients, compared to ST controls. …”
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Biologics as well as inhaled anti-asthmatic therapy achieve clinical remission: Evidence from the Severe Asthma Network in Italy (SANI) by Giorgio Walter Canonica, MD, Francesco Blasi, PhD, Pierluigi Paggiaro, MD, Enrico Heffler, PhD, Fulvio Braido, MD, Luisa Brussino, PhD, Giulia Scioscia, PhD, Cristina Cardini, MsC, Chiara Oriecuia, MsC, Isabella Sala, MsC, Vincenzo Bagnardi, PhD, Cecilia Calabrese, PhD, Gianna Camiciottoli, MD, Giovanna Elisiana Carpagnano, PhD, Stefano Centanni, PhD, Angelo Guido Corsico, PhD, Maria Teresa Costantino, MD, Claudia Crimi, PhD, Alice D'Adda, MD, Simona D’Alò, MD, Maria D'Amato, PhD, Corrado D'Andria, MD, Stefano Del Giacco, MD, Fabiano Di Marco, PhD, Nicola Cosimo Facciolongo, MD, Alessandro Farsi, MD, Manuela Latorre, PhD, Manlio Milanese, PhD, Eustachio Nettis, MD, Eleonora Nucera, MD, Giovanni Passalacqua, MD, Girolamo Pelaia, MD, Laura Pini, MD, Luisa Ricciardi, PhD, Fabio Luigi Massimo Ricciardolo, PhD, Luca Richeldi, PhD, Erminia Ridolo, PhD, Pierachille Santus, PhD, Nicola Scichilone, PhD, Gianenrico Senna, MD, Giuseppe Spadaro, MD, Antonio Spanevello, MD, Paolo Tarsia, MD

“…Asthma Control Test (ACT) and Asthma Control Questionnaire (ACQ) scores significantly impacted CR (p = 0.003 and p = 0.027, respectively), while biomarkers, namely IgE, blood eosinophils, or fractional exhaled nitric oxide (FeNO), were not associated with CR achievement. …”
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“CPR Posture” for Hemorrhage Control

“…Methods: Participants, recruited as a convenience sample, were randomized and instructed to use either two hands overlapping using arm strength only, or two hands overlapping with arms straight in a “CPR-like” position to apply force to a standardized hemorrhage control trainer with electronic feedback (Z-Medica), set to record a minimum pressure of 3-psi (155 mmHg); representing as satisfactory pressure to occlude blood flow. Participants were allowed to train for 30 seconds and then were asked to hold pressure at or above 3-psi for a three-minute time period. …”
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A Comparative study of Daiva's Sin and its Evolution in the Stories of Ancient Iran and Ta'ziehs of Daiva's Tying Thumb Based on Six Poetic Verses by Mahdi mohamadi, Adel Meghdadian, Abolfazl Tajik

“…The slap was so severe that his face was wounded and until he is healed by the Imam, blood and pus will come from it. (G2) Humiliation of the demon is one of the goals of Imam Ali which is stated in this text: I am a lion and you are a lowly fox foe me / O shameless, You are being captured by me now (p. 179). …”
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Prevalence of chronic kidney disease among Chinese adults with diabetes: a nationwide population-based cross-sectional studyResearch in context by Weiping Jia, Rong Yu, Limin Wang, Dalong Zhu, Lixin Guo, Jianping Weng, Hong Li, Mei Zhang, Xiaoqi Ye, Zhiguang Zhou, Dajin Zou, Qiuhe Ji, Xiaohui Guo, Yinan Zhang, Dong Lang, Jiarui Wu, Jing Wu, Xuhong Hou, Xiaohui Guo, Kai Wu, Liming Chen, Demin Liu, Guangyao Song, Linyi Shu, Jing Yang, Yan Wang, Dongmei Li, Qiansha Guo, Ling Li, Na Wu, Yadong Sun, Huifang Cheng, Hongyu Kuang, Huijuan Zhang, Weiping Jia, Xuhong Hou, Dalong Zhu, Jian Zhu, Hong Li, Fenping Zheng, Qiu Zhang, Honglin Hu, Gang Chen, Xingquan Yang, Xiaoyang Lai, Jianping Liu, Li Chen, Ming Dong, Zhigang Zhao, Jian Liu, Guangda Xiang, Junxia Zhang, Zhiguang Zhou, Jian Peng, Jianping Weng, Longyi Zeng, Yuzhen Liang, Guoqiao Li, Kaining Chen, Leweihua Lin, Qifu Li, Qingfeng Cheng, Xingwu Ran, Dawei Chen, Hong Li, Xin Nian, Lihui Yang, Shuyou Meng, Jing Xu, Junhong Long, Jing Liu, Qi Zhang, Qingxiang Dai, Xiaomin Xie, Guirong Bai, Jun Li, Tao Li, Zhong Dong, Tao Zhang, Sijia Liu, Yong Yang, Kun Geng, Wenlong Zheng, Zhihong Li, Hui Wang, Zuojun Wu, Miao Wang, Jixin Sun, Jianwei Zhou, Jun An, Huaqing Shen, Yanfang Li, Zeping Ren, Xiuli Xue, Shaohui Jia, Yongping Zheng, Jiaoxia Li, Yonggang Qian, Ping Ma, Yan Su, Liang Cao, Xuyi Yang, Guowei Pan, Guangzhi Pan, Ling Jin, Quanfu Yu, Yunfei Liu, Yingli Zhu, Zhifang Cheng, Jun Yang, Chundi Jia, Qing Wang, Shichun Yan, Jingyang Huang, Yumei Chi, Li Zhang, Ruifa Pang, Yan Shi, Yan Lu, Yiling Wu, Jie Yu, Chunxiang Wu, Jinyi Zhou, Yunxia Wu, Ning Zhang, Jing Sun, Xiumei Tian, Jieming Zhong, Jingying Chen, Kaixu Xie, Lingjuan Fu, Xiaohua Wang, Yeji Chen, Ling Zeng, Zhenqian Cao, Maomin Yang, Biao Hu, Wenling Zhong, Qingyan Liu, Zhiding Huang, Qingbin Lai, Yuyu Zhang, Liping Zhu, Yujing Zhao, Wuming Tao, Yonghai Tu, Lin Zhou, Xiaolei Guo, Benzheng Chai, Liping Ding, Yuewei Zou, Dongzhi Li, Li Hua, Shixian Feng, Jianli Guo, Wanguang Liu, Qingxiang Li, Yunzhi Zheng, Minli Xu, Lan Zhang, Chunbo Li, Yingchao Wan, Chi Hu, Shengping Xu, Biyun Chen, Huilin Liu, Xiaojia Bian, Wenwei Chen, Honghua Li, Yanjun Xu, Fan Weng, Hong Wu, Weijin Zhang, Liankai Zhu, Jun Meng, Jin Yang, Yongsong Zeng, Gaoke Zhai, Lingfeng Qin, Yi Lu, Zhenwang Fu, Shukuan Wu, Caigang Li, Na Wang, Lianfen Chen, Xianbin Ding, Qi Zhou, Yiling Xie, Rui Chen, Dongsheng Yang, Ying Deng, Youping Hu, Bo Huang, Ping Wang, Peng Cai, Changyan Peng, Xiaofang Chen, Ling Li, Liang Xiao, Chenglin Wang, Chaogang Tan, Daobin Chen, Min Chen, Mingfang Qin, Zhaomin Lei, Jianzhi Qiu, Wei Yu, Yunfei Li, Guoxia Bai, Ying Wang, Lin Qiu, Ning Wang, Xudong Zhao, Ani Yan, Jianfei Liu, Tingcai Wang, Kaihua Hao, Zaihong Zhang, Zhanqi Xian, Tenghuan Ma, Zhihua Xu, Yi Yang, Hongli Wang, Rong Li, Zhonggang Zhao, Caixia Fan, Purhati, Hongjun Xu, Liping Gao

“…CVH was evaluated using the “life's essential 8” (LE8) score, which ranged from 0 to 100 and included 8 components: diet, sleep duration, physical activity, nicotine exposure, hemoglobin A1c, blood pressure, non–high-density lipoprotein cholesterol, and body mass index. …”
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Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study by Adrian Edwards, Ridhi Agarwal, Janine Bates, Alison Bray, Sarah Milosevic, Emma Thomas-Jones, Michael Drinnan, Marcus Drake, Peter Michell, Bethan Pell, Haroon Ahmed, Natalie Joseph-Williams, Kerenza Hood, Yemisi Takwoingi, Chris Harding

“…The tests included prostate examination, prostate-specific antigen blood test, symptoms questionnaires and home-based urine flow measurements. …”
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Acute stress triggers sex-dependent rapid alterations in the human small intestine microbiota composition by Bruno K. Rodiño-Janeiro, Bruno K. Rodiño-Janeiro, Olfat Khannous-Lleiffe, Olfat Khannous-Lleiffe, Marc Pigrau, Marc Pigrau, Marc Pigrau, Jesse R. Willis, Jesse R. Willis, Eloísa Salvo-Romero, Eloísa Salvo-Romero, Eloísa Salvo-Romero, Adoración Nieto, Adoración Nieto, Elba Expósito, Elba Expósito, Elba Expósito, Marina Fortea, Marina Fortea, Cristina Pardo-Camacho, Cristina Pardo-Camacho, Cristina Pardo-Camacho, Mercé Albert-Bayo, Mercé Albert-Bayo, Ana María González-Castro, Ana María González-Castro, Ana María González-Castro, Ana María González-Castro, Danila Guagnozzi, Danila Guagnozzi, Danila Guagnozzi, Danila Guagnozzi, Cristina Martínez, Cristina Martínez, Cristina Martínez, Beatriz Lobo, Beatriz Lobo, Beatriz Lobo, Beatriz Lobo, María Vicario, María Vicario, Javier Santos, Javier Santos, Javier Santos, Javier Santos, Toni Gabaldón, Toni Gabaldón, Toni Gabaldón, Toni Gabaldón, Carmen Alonso-Cotoner, Carmen Alonso-Cotoner, Carmen Alonso-Cotoner, Carmen Alonso-Cotoner

“…We have evaluated changes in the small intestinal microbiota in response to acute stress to better understand stress-induced intestinal barrier dysfunction.MethodsJejunal biopsies were obtained at baseline and 90 min after cold pain or sham stress. Autonomic (blood pressure and heart rate), hormonal (plasma cortisol and adrenocorticotropic hormone) and psychological (Subjective Stress Rating Scale) responses to cold pain and sham stress were monitored. …”
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Single-cell transcriptome-wide Mendelian randomization and colocalization reveals immune-mediated regulatory mechanisms and drug targets for COVID-19Research in context by Hui Ying, Xueyan Wu, Xiaojing Jia, Qianqian Yang, Haoyu Liu, Huiling Zhao, Zhihe Chen, Min Xu, Tiange Wang, Mian Li, Zhiyun Zhao, Ruizhi Zheng, Shuangyuan Wang, Hong Lin, Yu Xu, Jieli Lu, Weiqing Wang, Guang Ning, Jie Zheng, Yufang Bi

“…Methods: We conducted a Mendelian randomization (MR) and colocalization analysis using 26,597 single-cell expression quantitative trait loci (sc-eQTL) to proxy effects of expressions of 16,597 genes in 14 peripheral blood immune cells and tested them against four COVID-19 outcomes from COVID-19 Genetic Housing Initiative GWAS meta-analysis Round 7. …”
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Cohort profile: the BangladEsh Longitudinal Investigation of Emerging Vascular and nonvascular Events (BELIEVE) cohort study by Anisur Rahman, Stephen Sutton, Mahbubur Rahman, Jason Crawte, Tahmeed Ahmed, Md Saimul Islam, Aliya Naheed, Adam S Butterworth, Emanuele Di Angelantonio, Matthew Walker, John Danesh, Angela Wood, Sarah Hawkes, Sadika Akhter, Catherine Perry, Aytalina Azarova, Ruchira T Naved, Meerjady Sabrina Flora, Nusrat Khan, Rajiv Chowdhury, Sohel Reza Choudhury, Nusrat Jahan, Stephen Kaptoge, Md Zahidul Islam, Kaniz Fatema, Kim Robin van Daalen, Shammi Luhar, Roderic L Jones, Abbas Bhuiya, Md Khalequzzaman, Syed Shariful Islam, Henry Taylor, Shamima Akter, Simon Griffin, Khairul Islam, Salma Akter, Ruchira Tabassum Naved, Abdul Malik, Rubhana Raqib, Animesh Talukder, Richard Houghton, Tahmina Shirin, Lawrence King, Kamrun Nahar, Samantha Farrow, Giulia Loffreda, Samsad Rabbani Khan, Valerie Rhenius, Nahida Akter, Md Mostafa Monower, Sabina Akter, Mantaka Rahman, Lisa Pennells, Maria L C Iurilli, Md Taslim Uddin Miah, Khan Mohammad Thouhidur Rahman, Sharraf Samin, Kazi Nazmus Saqeeb, Ishrat Tasmin, Eleanor Farrow, Ank Michielsen, Sarah Spackman, Charlotte van Coeverden, James Ajioka, Khondker Abdul Abdul Awal, Evangelia Chatzidiakou, Jörg Feldmann, Richard Fenner, Tuhin Haque, Sirajul Islam, Kamrul Hasan Khan, Fazila-Tun-Nesa Malik, Olalekan Popoola, Nicholas Mascie Taylor, Md Alfazal Khan, Israt Akter, Laboni Akter, Shoriful Islam, Mohammad Kamruzzaman, Monalisa Moni, A H M Rezwan, K M Thouhidur Rahman, Monjeline Sultana, Jesmin Akhter, Ayasha Akter, Bakul Akter, Jharna Akter, Jesmin Akter, Juba Akter, Khadiza Akter, Khadija Akter, Lipi Akter, Maksuda Akter, Mousumi Akter, Mst Lovely Akter, Nasima Akter, Samima Akter, Sema Akter, Shahida Akter, Shahnaj Akter, Taslima Akter, A T M Zorjis Alam, Mahmuda Atique, Lutfa Begum, Mst Nazma Begum, Farjana Choudhury, Mitali Paul Chowdhury, Robin Reza Chowdhury, Mukul Rani Debnath, Nahid Ferdash, Naima Ferdous, Md Rakib Al Hasan, Khandaker Hashanuzzaman, Shamima Haq, Md Riazul Haque, Alamgir Hossain, Md Ibrahim, Shahi Israt Jahan, Israt Jahan Jarin, Zohora Pradhan Jonaki, Asik Kabir, Tonema Kader, Md Mostafa Kamal, Sayed Kamruzzaman, Sadik Fatima Kanon, Nazmul Karim, Shamsul Karim, Tanuja Khanom, Shamim Ara Khatun, Badrun Nahar Lorin, Mst Sirajum Manira, Farhana Jahan Mary, Kazi Dilruba Mita, Lipi Mitra, Basudeb Mollik, Sudipta Nargis, Nusrat Alam Nawmee, Esrat Zahan Nesa, Mahmuda Akter Nipa, Mehenaz Parvin, Sanjida Parvin, Shahnaj Parvin, Suraiya Parvin, Nayan Rabidash, Rulia Rahman, Madhabi Rani, Shahjalal Sarker, Smriti Sarker, Razia Sultana Shathi, Fatema Shelly, Ireen Sultana, Rovaiya Sultana, Israt Jahan Sumi, Sharmin Tamanna, Khadija Akter Topy, Umme Habiba Urmee, Suraya Yesmin, Julianne Halley, Charlotte van Coeverden, Mahmuda Akther Akhi, Asia Akter, Labony Akter, Ms Mili Akter, Mst Shamima Akter, Setu Akter, Tahmina Akter, Md Sabdar Ali, Mst Jesmin Ara, Edyta Bujnik, Apu Chandra Das, Many Das, Nurjahan Fatema, Md Riyad Hasan, Soniya Jannat, Mst Amena Khatun, Most Nurnahar Khatun, William Mossman, Robyn Murdoch, Zannaton Naeem, Evrikleia Ntasi, Silvia Alonso Rodriguez, Tripty Roy, Most Abida Sultana, Laryssa Amado, Tanya Braune, Eilidh Cowan, Steve Ellis, Ellie Farrow, Hannah Lombardi, Niko Ovenden, Tamara Sabri, Md Khalid Sultan, Jim Ajioka, Khondker Abdul Awal, Arul Baradi, Emanuele Di Angelantonio, Camilla Faidutti, Joerg Feldmann, Louise Hair, Sharifuddin Hasnat, Shahid Akhter Hossain, Md Mominul Islam, Shafiul Islam, Joe Lavallée, Fazila Tun-Nesa Malik, Nick Mascie-Taylor, Md Sirajul Islam, Laurie Savage, Sara Shazad, Lalitha Sundaram, Aloka Tulukdar, Kim Van Daalen, Tanvir Chowdhury, Nurul Huda, Samia Naz Isha, Riaz Hossain Khan, Aliva Salmeen, Zeeba Zahra Sultana

“…Anthropometric measurements and blood pressure were recorded for each participant. …”
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Selected Abstracts of the 20th International Workshop on Neonatology and Pediatrics; Cagliari (Italy); October 23-26, 2024 by --- Various Authors

“…Raiola (Catanzaro and Brescia, Italy) ABS 51. A STUDY OF CORD BLOOD ALKALINE PHOSPHATASE AS A PREDICTOR OF NEONATAL HYPERBILIRUBINEMIA IN A TERTIARY HOSPITAL • V.B. …”
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