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12821
Oxycodone for analgesia in children undergoing endoscopic retrograde cholangiopancreatography: a randomized, double-blind, parallel study
Published 2025-01-01“…Additionally, inflammatory cytokines in the serum, including tumor necrosis factor (TNF)-α, interleukin (IL)-6, and IL-10 were examined by blood sampling at baseline, 6 h, and 24 h after ERCP.ResultsCompared to fentanyl, children receiving oxycodone had significantly lower pain scores at 30 min, 6 h, and 24 h after ERCP, while the scores at 10 and 20 min were similar in both groups. …”
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12822
Ionizable polymeric micelles (IPMs) for efficient siRNA delivery
Published 2025-01-01“…Abstract Lipid nanoparticles (LNPs) are widely used for nucleic acid delivery but face challenges like limited targeting and accelerated blood clearance (ABC) effect. We design three ionizable oligomers (IOs) that, with polylactide-polyethylene glycol (PLA-PEG), form a potential siRNA delivery system, named Ionizable Polymeric Micelles (IPMs). …”
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12823
Effect of antioxidant capsule supplementation on oxidative stress markers in hypertensive patients
Published 2024-01-01“…Study participants received placebo capsules for 4 weeks, then fruit extract capsules (blueberry, cranberry and pomegranate), one capsule of each per day for 4 weeks. Blood pressure was measured at baseline, after the use of placebo and antioxidant capsules. …”
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12824
Treatment Planning Strategies for Interstitial Ultrasound Ablation of Prostate Cancer
Published 2024-01-01“…Results: For generic prostate tissue, 360 treatment schemes were simulated based on the number of transducers (1-4), applied power (8-20 W/cm2), heating time (5, 7.5, 10 min), and blood perfusion (0, 2.5, 5 kg/m3/s) using forward treatment modelling. …”
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12825
The Monocyte-to-Lymphocyte Ratio at Hospital Admission Is a Novel Predictor for Acute Traumatic Intraparenchymal Hemorrhage Expansion after Cerebral Contusion
Published 2020-01-01“…MLR was acquired from routine blood tests upon admission. We constructed two predictive models: basic combined model of clinical and imaging variables and MLR combined model of both MLR and other variables in the basic model. …”
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12826
Experimental evidence-based construction of electroacupuncture for ischemic stroke: a meta-analysis and systematic review
Published 2025-02-01“…The heterogeneity of the included studies points to complex underlying mechanisms, potentially involving modulation of apoptotic pathways and cerebral blood flow.ConclusionThis meta-analysis substantiates the neuroprotective potential of EA in ischemic stroke models, primarily through apoptosis modulation and possibly through improved cerebral perfusion. …”
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12827
High-fat diet promotes gestational diabetes mellitus through modulating gut microbiota and bile acid metabolism
Published 2025-01-01“…Body weight, average feed intake, blood glucose, insulin levels and oral glucose tolerance test was performed among each groups. …”
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12828
Epidemiological Characteristics and Prognostic Scoring in Toxic Epidermal Necrolysis and Stevens–Johnson Syndrome: Insights from a 17-Year Burn Center Experience
Published 2025-01-01“…Affected body surface area, platelet count, and serum blood urea nitrogen differed significantly between survivors and non-survivors. …”
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12829
Intravesical BCG in patients with non-muscle invasive bladder cancer induces trained immunity and decreases respiratory infections
Published 2023-01-01“…Ex vivo cytokine production by peripheral blood mononuclear cells, epigenetic modifications, and changes in the monocyte transcriptome were measured. …”
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12830
Enhancing surveillance for dengue fever in Oyo State, Nigeria – a one health approach
Published 2025-01-01“…It involved screening DENV in 289 febrile human blood samples and 1,015 Aedes species mosquitoes. …”
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12831
Oxygenation targets for endovascular therapy in acute ischemic stroke patients (Oxy-TARGET): protocol for a single-centre, open-label randomised controlled trial
Published 2025-01-01“…Additional safety and efficacy parameters included the 24-hour ΔNIHSS (baseline NIHSS - NIHSS at 24-hour) score, final infarct volume at 72 hours postrandomisation, 90-day Modified Rankin Scale (mRS) score, early neurological deterioration, postoperative pulmonary complications, blood gas parameters, symptomatic intracranial haemorrhage and 90-day mortality.Ethics and dissemination Following a rigorous review process, Oxy-TARGET has received official approval from the Ethics Committee of Beijing Tiantan Hospital, Capital Medical University (KY2023-257-02). …”
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12832
Case report: JAK inhibitor treatment of immune dysregulation symptoms in a patient with PTPN2 deficiency
Published 2025-01-01“…At the 9- and 16-month checkpoint, after 6 and 13 months correspondingly of monotherapy with ruxolitinib at a dosage of 30 mg per day, the patient had stable blood counts, lymphadenopathy decreased, and the lung interstitial disease improved. …”
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12833
Inflammatory Markers and Severity in COVID-19 Patients with Clostridioides Difficile Co-Infection: A Retrospective Analysis Including Subgroups with Diabetes, Cancer, and Elderly
Published 2025-01-01“…This study aimed to characterize inflammatory markers and composite inflammatory severity scores—such as Acute Physiology and Chronic Health Evaluation II (APACHE II), Confusion, Urea, Respiratory rate, Blood pressure, and age ≥ 65 years (CURB-65), National Early Warning Score (NEWS), and the Systemic Immune-Inflammation Index (SII)—in hospitalized Coronavirus Disease 2019 (COVID-19) patients with and without CDI, and to evaluate their prognostic implications across key clinical subgroups. …”
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12834
Clinical Outcomes in Diabetic Females Presenting with STEMI: A Cohort Study
Published 2025-01-01“…They presented later, with higher blood sugar (p-value <0.0001) and creatinine values (p-value=0.009) and had a lower Ejection Fraction (EF) (p-value=0.003). …”
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12835
Limited restoration of T cell subset distribution and immune function in older people living with HIV-1 receiving HAART
Published 2025-01-01“…Method This study was conducted at Yunnan AIDS Care Center, China, to explore the immunological responses of old PLWH to HAART and compared with the middle-age and the younger. Blood samples were collected from 146 PLWH to analyze T cell subsets and their functions, with a particular emphasis on markers related to T cell differentiation, activation, exhaustion, inflammation, and cellular function, using multicolor flow cytometry analysis. …”
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12836
Manual of Clinical anesthesiology :
Published 2021Table of Contents: “…-- Hemodynamic collapse following a mainstem intubation -- Hypoxemia during tracheostomy -- Anesthetic depth and mask ventilation in the prone position -- Jet ventilation through a cookgas airway exchange catheter -- End of case evaluation and management of a patient post airway mass excision -- Possible recurrent laryngeal nerve injury -- Obstructive sleep apnea, and dead in bed -- Bilevel positive air pressure, decreased sensorium, aspiration and capnography -- Perioperative management of a patient previously treated with bleomycin undergoing thoracic surgery -- Intra-operative airway fire -- Obesity hypoventilation syndrome -- Circulation-related cases -- Hemorrhage during endovascular repair of thoracic aorta -- Pacemakers and automatic implantable cardioverter defibrillators -- Acute myocardial infarction during laparoscopic surgery -- Sickle cell and preeclampsia -- Dysrhythmias in a patient with Crohn's disease -- Hematologic disorders: hemophilia and disseminated intravascular coagulation -- Blood transfusion and the Jehovah's Witness patient -- Cardiac and pulmonary contusions -- Intraoperative coagulopathy -- Hypotension in chronic methamphetamine user -- Venous air embolism during arteriovenous malformation repair -- Cardiac tamponade -- Case of intraoperative new-onset atrial fibrillation -- Valvular disease -- Obstetrics-related cases -- Labor epidural with unrecognized dural puncture, causing high sensory block, hypotension, fetal bradycardia and post dural puncture headache -- Acute pulmonary dysfunction immediately after cesarean delivery under general anesthesia -- Jehovah's Witness with placenta previa and increta for cesarean hysterectomy -- A pregnant patient with mitral stenosis -- Unrecognized uterine hyperstimulation due to oxytocin and combined spinal-epidural analgesia -- Super morbidly obese patient for elective repeat cesarean section -- Probable amniotic fluid embolus -- Emergent cesarean section -- Pregnancy plus atrial septal defect vs Eisenmenger Syndrome -- Uterine abruption -- Pediatric-related cases -- Neonatal resuscitation following spontaneous vaginal delivery -- Anxious, coughing and bound to obstruct -- Special diseases/conditions/situations -- Hypothermia during laparoscopic nephrectomy -- Operating room management case scenarios -- Anaphylaxis reactions -- Autonomic dysreflexia -- Porphyrias -- Monitored anesthesia care: medical implications; and wrong-sided operations: legal implications -- Diabetic ketoacidosis in the urgent anesthesia setting -- Fever, altered mental status, and rigidity in the perioperative course -- Neuro/neuromuscular-related cases -- Emergent craniotomy for evacuation of epidural hematoma -- Hyperkalemia and residual neuromuscular blockade after kidney transplantation -- A defasciculating dose of nondepolarizing neuromuscular blocker -- Postoperative monocular vision loss -- Delayed emergence after aneurysm clipping -- Pain and regional anesthesia related cases -- Unintentional dural puncture in a patient with severe preeclampsia -- Complex regional pain syndrome -- Vascular absorption of local anesthetic producing systemic toxicity -- Inadvertent high spinal in parturient -- Outpatient surgery-related cases -- Plastic surgery in a surgeon's office -- Orthopedic surgery in an ambulatory surgicenter -- Eye surgery at an outpatient surgicenter -- Endoscopic sinus surgery at an outpatient sugicenter.…”
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12837
Surgeon Preference and Clinical Outcome of 3D Vision Compared to 2D Vision in Laparoscopic Surgery: Systematic Review and Meta-Analysis of Randomized Trials
Published 2024-06-01“…This benefit was mostly seen in bariatric surgery (−16.3%; 95% CI, −1.28 to −0.21; P = 0.006; 2 studies; n = 58; I2 = 0%) and general surgery (−6.7%; 95% CI, −0.34 to −0.01; P = 0.036; 9 studies; n = 1056; I2 = 41%). Blood loss was nonsignificantly reduced by 3D vision (SMD, −0.33; 95% CI, −0.68 to 0.017; P = 0.060; n = 1830; I2 = 92%). …”
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12838
Dietary supplementation of mulberry leaf oligosaccharides improves the growth, glucose and lipid metabolism, immunity, and virus resistance in largemouth bass (Micropterus salmoide...
Published 2025-01-01“…Moreover, the MLOL and MLOH group had significantly lower contents of triglyceride, blood glucose, and malondialdehyde and activities of serum alanine aminotransferase and aspartate aminotransferase, while significantly higher levels of serum and liver total superoxide dismutase and lower levels of glutathione than the CK group (P< 0.05). …”
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12839
Diagnostic properties of differing BP thresholds for adverse pregnancy outcomes in standard-risk nulliparous women: A secondary analysis of SCOPE cohort data.
Published 2025-01-01“…<h4>Background</h4>In 2017, the American College of Cardiology and American Heart Association (ACC/AHA) lowered blood pressure (BP) thresholds to define hypertension in adults outside pregnancy. …”
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12840
Impact of Cordyceps sinensis on coronary computed tomography angiography image quality and renal function in a beagle model of renal impairment
Published 2025-01-01“…Renal function was assessed using MRI before and after the intervention, with IVIM (Intravoxel Incoherent Motion) and BOLD (Blood Oxygen Level Dependent) imaging of the kidneys. …”
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