Impact of the COVID-19 pandemic on type 2 diabetes care and factors associated with care disruption in Kenya and Tanzania by Richard E. Sanya, Caroline H. Karugu, Peter Binyaruka, Shukri F. Mohamed, Lyagamula Kisia, Peter Kibe, Irene Mashasi, Grace Mhalu, Christopher Bunn, Manuela Deidda, Frances S. Mair, Eleanor Grieve, Cindy M. Gray, Sally Mtenga, Gershim Asiki

“…A questionnaire captured data on blood glucose testing, changes in medication prescription and access, and healthcare provider access. …”
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Activated Growth Factor From Platelets as Treatment for Diabetic Retinopathy Through Antioxidant-Oxidative Stress Pathway by Amin R, Hidayat R, Maritska Z, Putri TW

“…This study was aimed to evaluate activated growth factor (AGF) from platelet for diabetic retinopathy treatment, utilizing an in vivo investigation to regulate the antioxidant-oxidative stress pathway.Methods: The activated growth factor was initially derived by extracting intravenous blood from the rats. Advanced glycation end products (AGEs), p38 mitogen activated protein kinase (p38 MAPK), nuclear factor-κβ (NF-κβ), reactive oxygen species (ROS), tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1), superoxide dismutase (SOD) and vascular endothelial growth factor (VEGF) was assessed using enzyme linked immunoassay (ELISA). …”
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Harnessing the power of proteins in modulation of miRNAs for targeting Iron deficiency Anemia: Opinion for future implications and strategies by Ray Wagiu Basrowi, Ray Wagiu Basrowi, Ray Wagiu Basrowi, Tonny Sundjaya, Tonny Sundjaya, Dessy Pratiwi, Nurlinah Amalia, Nurlinah Amalia, Nurlinah Amalia, Yosi Yohanes Putra Tandi, Muhammad Yasir Syafa’atulloh, Garuda Nusantara Putra Utomo, Muhammad Abdir Rahman Albarok, Fahrul Nurkolis

“…Proteins, acting as modulators of miRNA activity, present innovative pathways for intervention by influencing erythropoiesis at multiple stages, from stem cell proliferation to red blood cell maturation. Our synthesis highlights key molecular mechanisms: miR-15a suppresses erythropoiesis by inhibiting c-Myb, miR-24 impairs heme biosynthesis through ALK4 regulation, while miR-150 and miR-223 modulate critical hematopoietic pathways affecting cell differentiation and apoptosis. …”
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Impact of noninsulin-dependent diabetes mellitus (level of control) on sex hormone profile and erectile function by Abdullah A. Khawaji, Hossam S. El-Tholoth, Muath A. Albarakati, Bander A. Binjabaan, Abdulaziz Alzahrani, Abdulmajeed Althobity, Abdulmalik Almardawi, Khaled Bedaiwi, Mussa AlNuami

“…Retrieved data include patient’s demographics, body mass index (BMI), hormonal profile, Complete Blood Count (CBC), lipid profile, prostate-specific antigen (PSA), urate, Vitamin D level, and the severity of ED as assessed by the International Index of Erectile Function (IIEF) scores. …”
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Community-Based Assessment of Knowledge, Attitudes, and Practices Towards COVID-19: an Epidemiological Survey in Kurdistan Region, Iraq by Zhino Rawf Ali, Bayan Omar Sharif, Aram Salih Mohammed Amin Kamali, Varin Tofiq Abbas, Azad Karim Ahmed, Shaho Osman Mahmood, Chiman Jamal ahmed, Sarwat Ahmed Abdulqader

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Development of a Machine‐Learning Model for Diagnosis of Pancreatic Cancer from Serum Samples Analyzed by Thermal Liquid Biopsy by Sonia Hermoso‐Durán, Nicolas Fraunhoffer, Judith Millastre‐Bocos, Oscar Sanchez‐Gracia, Pablo F. Garrido, Sonia Vega, Ángel Lanas, Juan Iovanna, Adrián Velázquez‐Campoy, Olga Abian

“…An innovative approach based on differential scanning calorimetry (DSC) of blood serum samples, thermal liquid biopsy (TLB), combined with machine‐learning (ML) analysis, may offer a more efficient method for diagnosing PDAC. …”
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Prognostic significance of perioperative circulating CD56bright NK cell and recovery of NK cell activity in patients with colorectal cancer undergoing radical surgery by Jeng-Fu You, Cheng-Chi Lee, Yun-Shien Lee, Yih-Jong Chern, Chun-Kai Liao, Hung-Chih Hsu

“…Methods: We prospectively enrolled 45 patients with CRC. Venous blood samples were collected preoperatively and on postoperative day 3 (POD3) and 30 (POD30). …”
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Retrospective evaluation of risk factors for worsening renal function after angiotensin‐converting enzyme inhibitor treatment in dogs by Yelim Lee, Minju Baek, Dongseop Lee, Jinyeong Park, Yeon Chae, Byeong‐Teck Kang, Taesik Yun, Hakhyun Kim

“…Demographic and serum chemistry data, such as total protein, albumin, blood urea nitrogen, creatinine, symmetric dimethylarginine, glucose, triglyceride, total cholesterol concentrations, and serum electrolyte concentrations at first presentation, were evaluated. …”
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Study of antifungal susceptibility pattern of various Candida species with reference to conventional and automated methods in a tertiary care hospital by Paulami De, Rehena Sarkar, Raja Ray, Kumkum Bhattacharyya, Hasina Banu, Hirak Jyoti Raj

“…Maximum number of isolates came from central line catheter 43, followed by blood 19. other samples from where candida were isolated are urine 13, endotracheal aspirate 9, Pleural fluid 7, Bronchoalveolar lavage 3, Cerebrospinal Fluid 3 and Wound 3. …”
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Actors influencing cancer-related fatigue and the construction of a risk prediction model in lung cancer patients by Mei-Ning Zhang, Yi-Chen Zhou, Zhu Zeng, Cun-Liang Zeng, Bo-Tao Hou, Gui-Rong Wu, Qiao Jiao, Dai-Yuan Ma

“…A CRF risk prediction model was then established, with its predictive performance and calibration evaluated using ROC curves.FindingsThe results of multivariate logistic regression analysis showed that gender, age, education level, living status, daily exercise, clinical stage, course of disease, treatment mode, chronic disease, BMI, hemoglobin, serum albumin, blood glucose, potassium concentration, magnesium concentration, PSQI score and HAD score were the influencing factors of CRF in lung cancer patients (P<0.05). …”
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Establishing of a risk prediction model for metabolic dysfunction-associated steatotic liver disease: a retrospective cohort study by Nan Li, Chenbing Liu, Zhangfan Lu, Wenjian Wu, Feng Zhang, Lihong Qiu, Chao Shen, Di Sheng, Zhong Liu

“…Results Our study indicated that male, body mass index (BMI), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), fasting plasma glucose (FPG), serum uric acid to creatinine ratio (SUA/Cr) and white blood cell (WBC) were associated with MASLD incidence. …”
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Changes in the visual analyzer occurring as a result of space flight by M.A. Valyakh, N.G. Baeva

“…<br> Over the past few years, NASA officers have repeatedly recorded changes in the visual organ of astronauts after long space missions, in particular, they manifested an optic nerve swelling, a reduction in the anterior-posterior axial length of the eye, a change in blood flow velocity, and hypermetropia. European scientists obtained similar data. …”
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Longitudinal Evaluation of Myocardial Fatty Acid and Glucose Metabolism in Fasted and Nonfasted Spontaneously Hypertensive Rats Using MicroPET/CT by Jennifer S. Huber PhD, Andrew M. Hernandez PhD, Mustafa Janabi PhD, James P. O’Neil PhD, Kathleen M. Brennan DVM, Stephanie T. Murphy BS, Youngho Seo PhD, Grant T. Gullberg PhD

“…Compartment modeling was used to estimate the rate constants for the radiotracers. Blood samples were obtained and analyzed for glucose and free fatty acid concentrations. …”
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Glycyrrhizinate Monoammonium Cysteine-Loaded Lipid Nanoparticles Allow for Improved Acute Liver Injury Therapy by Yunjie Xu, Pinghui Li, Shiran Sun, Yulin Chen, Lixia Feng, Dawei Jiang, Chidan Wan, Jianbo Li, Xiong Cai

“…The therapeutic effects of LNP-GMC and pure GMC on the ALI model were evaluated using fibroblast activation protein inhibitor (FAPI) PET imaging, blood biochemical indicators, and liver pathology slices. …”
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Can Underlying Co-Morbidities Affect Cerebral Oximetry in Cardiac Surgery Patients? by Kianoush Saberi, Shahnaz Sharifi, Amirhossein Orandi

“…Following admission to the operating room, standard monitoring of vital signs, including non-invasive blood pressure (NIBP), electrocardiogram (ECG), central venous pressure (CVP), oxygen saturation (SpO2), and end-tidal carbon dioxide (ETCO2), was established. …”
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A covalent peptide-based lysosome-targeting protein degradation platform for cancer immunotherapy by Youmei Xiao, Zhuoying He, Wanqiong Li, Danhong Chen, Xiaoshuang Niu, Xin Yang, Wenxuan Zeng, Mengfan Wang, Yuzhen Qian, Ye Su, Feiyu Luo, Guanyu Chen, Juan Liu, Xinghua Sui, Xiuman Zhou, Yanfeng Gao

“…The ability of antibody-based LYTACs to penetrate solid tumor is limited as well, especially to cross the blood-brain barrier (BBB). Here, we propose a covalent chimeric peptide-based targeted degradation platform (Pep-TACs) by introducing a long flexible aryl sulfonyl fluoride group, which allows proximity-enabled cross-linking upon binding with the protein of interest. …”
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Airway morphology, hyoid position, and serum inflammatory markers of obstructive sleep apnea in children treated with modified twin-block appliances by Jun Duan, Wanyuan Xia, Xuelei Li, Feng Zhang, Fan Wang, Mengwei Chen, Qian Chen, Bing Wang, Bing Li

“…Postoperative and preoperative polysomnography, lateral cephalometric radiographs, and peripheral blood samples were collected. The control group comprised children with class I without mandibular retrognathia. …”
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IL-6 and PD-1 antibody blockade combination therapy regulate inflammation and T lymphocyte apoptosis in murine model of sepsis by Song I Lee, Na Young Kim, Chaeuk Chung, Dongil Park, Da Hyun Kang, Duk Ki Kim, Min-Kyung Yeo, Pureum Sun, Jeong Eun Lee

“…IL-6 blockade, PD-1 blockade, or combination of both was administered 24 h after CLP. Peripheral blood count, cytokine level, lymphocyte apoptosis in the spleen, neutrophil infiltration in the lungs and liver, and survival rate were measured. …”
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Copper Deficiency in Sheep with High Liver Iron Accumulation by Isadora Karolina Freitas de Sousa, Antonio Humberto Hamad Minervino, Rejane dos Santos Sousa, Dowglish Ferreira Chaves, Herbert Sousa Soares, Isabella de Oliveira Barros, Carolina Akiko Sato Cabral de Araújo, Raimundo Alves Barrêto Júnior, Enrico Lippi Ortolani

“…Liver biopsies were performed and blood was collected to determine hepatic and plasmatic Cu, iron (Fe), and zinc (Zn) concentration, respectively. …”
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Analysis of the terms of development of infectious complications in patients after osteosynthesis of long bones by P.V. Tanasienko, H.B. Kolov, V.M. Tsokalo

“…In all observation groups, the infectious process localized in the tibia, which has both anatomical reasons and reasons related to the blood supply of this segment, was detected the most often.…”
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