The Constellation of Macrovascular Risk Factors in Early Onset T2DM: A Cross-Sectional Study in Xinjiang Province, China by Mingchen Zhang, Jiangfeng Mao, Ablikm Tuerdi, Xiaoyun Zeng, Li Quan, Shan Xiao, Jun Zhu, Hua Yao

“…Compared to the control, early onset patients had higher blood pressure and worse lipid profiles (all P<0.01). …”
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Midgut immune profiling and functional characterization of Aedes aegypti ABC transporter gene(s) using systemic and local bacterial challenges by Vikas Kumar, Shilpi Garg, Diksha Sisodia, Lalita Gupta, Sanjeev Kumar, Vishal Saxena

“…Furthermore, the transcriptional alterations of midgut ABC transporters were explored at different time points upon a thoracic nano-injection (systemic challenge) or infectious blood meal (local challenge) of the bacterial mixture through quantitative real-time PCR (qPCR), and one gene was selected for RNAi-mediated gene silencing and its role assessment in midgut immune responses. …”
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Multicentre, randomised controlled trial to investigate the effects of parental touch on relieving acute procedural pain in neonates (Petal) by Eleri Adams, Daniel Crankshaw, Ria Evans Fry, Rebeccah Slater, Caroline Hartley, Maria M Cobo, Fiona Moultrie, Annalisa G V Hauck, Vaneesha Monk, Shellie Robinson, Marianne van der Vaart, Luke Baxter, Ravi Poorun, Aomesh Bhatt

“…A total of 112 neonates born at 35 weeks’ gestation or more requiring a blood test in the first week of life will be recruited and randomised to receive parental stroking either preprocedure or postprocedure. …”
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NIR Triggered Bionic Bilayer Membrane-Encapsulated Nanoparticles for Synergistic Photodynamic, Photothermal and Chemotherapy of Cervical Cancer by Ding J, Zhang X, Guo L, Xiong J, Zhang C, Du Z, Zhu L, Alifu N, Dong B

“…For in vivo analysis, the antitumor properties of the nanoparticles were explored in a mouse subcutaneous tumor model.Results: RBC@ICG-DOX NPs were successfully prepared with strong safety and good blood compatibility, which can effectively reduce drug leakage and prolong drug circulation time in the body. …”
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Associated factors and prognostic implications of neutropenia in individuals with HIV/AIDS by Pengpeng Li, Xiaoyan Lv, Hui Shen, Jiamin Fang, Mingrui Wei, Xiaoyan Liu, Fuling Zhou

“…We analyzed the co-infections, blood routine test, infection indicators, lymphocyte subpopulation, bone marrow cell cytology, bone marrow morphology in both groups. …”
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Advances in Cell and Immune Therapies for Melanoma by Tanase Timis, Sanda Buruiana, Delia Dima, Madalina Nistor, Ximena Maria Muresan, Diana Cenariu, Adrian-Bogdan Tigu, Ciprian Tomuleasa

“…While CAR-T cell therapy has been less successful in melanoma compared to blood cancers, ongoing research is addressing challenges like the tumor microenvironment and antigen specificity. …”
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Pharmacokinetics of difloxacin after single intravenous, oral and intramuscular administration in pigeons by Yang-Guang Jin, Yue Liu, Yan-Ni Zhang, Yu-Xin Chen, Long-Ji Sun, Shi-Hao Li, Wen-Rui Wang, Fan Yang

“…Difloxacin was administered at 10 mg/kg body weight (BW) via each route. Blood samples were collected at various intervals from 0 to 48 h, and plasma was analyzed for difloxacin concentrations using a validated high-performance liquid chromatography (HPLC) method. …”
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Dapagliflozin improves diabetic kidney disease by inhibiting ferroptosis through β-hydroxybutyrate production by Yan Tian, Chenxia Zhou, Qun Yan, Ziyi Li, Da Chen, Bo Feng, Jun Song

“…This study hypothesized that SGLT2i could alleviate diabetic kidney injury by inhibiting ferroptosis and explored its potential mechanisms.Methods C57BL/6J mice were randomly divided into the control, DKD, DKD+dapagliflozin, and DKD+insulin treatment groups. Blood glucose levels and body weight were monitored. …”
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Impact of irradiation conditions on therapy of Lewis lung carcinoma in mice using glucose-ethylenediamine carbon dots by Pavlo Lishchuk, Halyna Kuznietsova, Taisa Dovbynchuk, Nataliia Dziubenko, Liudmyla Garmanchuk, Sergei Alekseev, Mykola Isaiev, Nataliya Pozdnyakova, Artem Pastukhov, Nataliya Krisanova, Tatiana Borisova, Vladimir Lysenko, Valeriy Skryshevsky

“…According to hematological analysis, treatment with GE-NPs caused an increase in red blood cells and hematocrit up to the healthy control levels. …”
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Dietary omega-3 fatty acids affect the growth performance of broiler chickens reared at high stocking density by Shahgol Rahbari, Abdolreza Salehi, Seyed Davood Sharifi, Shirin Honarbakhsh

“…The present study was conducted to investigate the effects of dietary omega-3 fatty acids in broiler chickens exposed to high stocking density (SD) on growth performance, carcass characteristics, breast meat quality, blood biochemical indices, nutrient digestibility and litter quality. …”
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Contemporary Results of Transcatheter Aortic Valve Replacement in Obese Patients by T. Owais, M. El Garhy, P. Lauten, M. Haensig, H. Lapp, P. C. Schulze, T. Kuntze

“…The rate of vascular complication was higher in patients with BMI ≥ 25 kg/m2. However, the rate of blood transfusion was higher in patients with BMI < 25 kg/m2. …”
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A Clinical Monitoring Program of COVID-19 Outpatients: A Prospective Cohort Study by Hossein Kasiri, Cyrus Mahjub, Mohammadreza Mazaeri, Fahimeh Naderi-Behdani, Aliyeh Bazi, Monireh Ghazaeian, Sahar Fallah

“…C-reactive protein, white blood cell, lymphocyte, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and hemoglobin levels were recovered significantly during the first two weeks (P<0.001). …”
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Myxedema Psychosis: Neuropsychiatric Manifestations and Rhabdomyolysis Unmasking Hypothyroidism by Sundus Sardar, Mhd-Baraa Habib, Aseel Sukik, Bashar Tanous, Sara Mohamed, Raad Tahtouh, Abdelrahman Hamad, Mouhand F. H. Mohamed

“…Additional investigations revealed a high thyroid-stimulating hormone (TSH) of 56.6 mIU/L, low free T4<0.5 pmol/L, elevated creatine kinase of 3601 U/L, and urine dipstick positive for blood, suggestive of myoglobinuria. MRI of the head was unremarkable. …”
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Impact of MMP2 rs243865 and MMP3 rs3025058 Polymorphisms on Clinical Findings in Alzheimer’s Disease Patients by Vladimira Durmanova, Juraj Javor, Zuzana Parnicka, Gabriel Minarik, Agata Ocenasova, Barbora Vaseckova, Veronika Reznakova, Maria Kralova, Tomas Hromadka, Ivana Shawkatova

“…In the brain, the pathological role of MMPs includes the disruption of the blood-brain barrier leading to the induction of neuroinflammation. …”
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Chloroquine and Rapamycin Augment Interleukin-37 Expression via the LC3, ERK, and AP-1 Axis in the Presence of Lipopolysaccharides by Xiaoyi Shi, Chunhui Lai, Lianyu Zhao, Mingying Zhang, Xi Liu, Shanqin Peng, Weizhong Guo, Qiuying Xu, Song Chen, Guang-xing Chen

“…Healthy human peripheral blood mononuclear cells were treated similarly to confirm our results. …”
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Epidemiology of Lumbar Puncture and the Validity of Meningeal Signs in Predicting Meningitis in Children: A Cross-sectional Study by Mehjabin, Shiji Joseph, Arun Ravi, Kalyani Pillai

“…A checklist was prepared for all the patients, where demographic data, clinical presentations, findings of CSF, and blood analysis were recorded. The data obtained were analysed using Statistical Package for Social Sciences (SPSS) version 23.0. …”
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Exacerbation of diabetes due to F. Nucleatum LPS-induced SGLT2 overexpression in the renal proximal tubular epithelial cells by Aiko Seki, Koichiro Kajiwara, Jumpei Teramachi, Masahiko Egusa, Takuya Miyawaki, Yoshihiko Sawa

“…Methods The induction of the SGLT2 by F. nucleatum LPS (Fn-LPS) were investigated in the streptozotocin-induced diabetic mouse renal tissue and cultured renal proximal epithelial cells. The changes of blood glucose levels and survival curves in diabetic mice with Fn-LPS were analyzed. …”
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The prevention opportunities of retinopathy in diabetic patients – position paper endorsed by the Polish Lipid Association by Maciej Banach, Stanisław Surma, Grzegorz Dzida, Jacek Jóźwiak, Bogusław Okopień, Jacek Rysz, Konrad Szosland, Andrzej Grzybowski

“…Thus, given the obesity (the prevalence of 30% in Poland) and diabetes (10% which is predicted to be doubled in next 25 years) epidemic, we should look for the effective methods not only to optimize fasting blood glucose and haemoglobin A1C, but also atherogenic dyslipidaemia and their complications, including retinopathy. …”
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Phytocompounds from Indonesia Medicinal Herbs as Potential Apelin Receptor Agonist for Heart Failure Therapy: An In-silico Approach by Muhamad Rizqy Fadhillah, Wawaimuli Arozal, Muhammad Habiburrahman, Somasundaram Arumugam, Heri Wibowo, Suci Widya Primadhani, Aryo Tedjo, Surya Dwira, Nurul Gusti Khatimah

“…Gambogic acid demonstrated favorable pharmacokinetic properties: good bioavailability, minimal blood-brain barrier penetration, no cytochrome P450 (CYP) enzyme interactions, and low toxicity. …”
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Analysis of Mannose‐Binding Lectin Protein and mRNA Levels on Selected Chicken Breeds in South Africa by Peter Ayodeji Idowu, Takalani J. Mpofu, Oliver T. Zishiri, Khathutshelo A. Nephawe, Bohani Mtileni

“…Objective To detect and quantify the MBL protein concentration and chicken MBL expression in selected chicken breeds in South Africa. Methods Forty‐five blood samples from three indigenous chicken breeds, Ovambo (OV = 9), Venda (VD = 9) and Potchefstroom Koekoek (PK = 9), and two exotic chicken breeds, Rhode Island Red (RIR = 9) and Lohmann Brown (LB = 9), were used for MBL protein concentration using enzyme‐linked immunosorbent assay (ELISA) techniques. …”
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