Detection of early relapse in multiple myeloma patients by Tereza Růžičková, Monika Vlachová, Lukáš Pečinka, Monika Brychtová, Marek Večeřa, Lenka Radová, Simona Ševčíková, Marie Jarošová, Josef Havel, Luděk Pour, Sabina Ševčíková

“…Results Using small RNA sequencing, we profiled microRNA expression in peripheral blood in three groups of MM patients who relapsed at different intervals. …”
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A prospective study to evaluate high dose daptomycin pharmacokinetics and pharmacodynamics in spp. infective endocarditis by Simona De Gregori, Annalisa De Silvestri, Mara Capone, Vincenzina Monzillo, Paola Giordani, Raffaele Bruno, Elena Seminari

“…All patients showed a microbiologic response with negative blood cultures by day 5 (1–3 interquartile rate (IQR) 3–8). …”
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Nursing care of a patient with intracerebral hemorrhage due to ruptured cerebral arteriovenous malformation and neurogenic pulmonary edema (1例脑动静脉畸形破裂出血并发神经源性肺水肿患者的护理)... by CAO Xiumin (曹秀敏), TANG Dongmei (唐冬梅)

“…Based on the monitoring of postoperative vital signs of the patient, efforts were made in the following aspects: Early identification and intervention on normal perfusion pressure breakthrough syndrome; Ensuring the effective cerebral perfusion pressure during control of blood pressure and intracranial pressure; Early identification and nursing of neurogenic pulmonary edema; Enhancing the postoperative airway, fluid and volume management; Providing lung protective ventilation strategy; Carrying out awakenings and awareness recovery for the patient with chronic disorders of consciousness. …”
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Astrocytes phenomics as new druggable targets in healthy aging and Alzheimer’s disease progression by Daniele Lana, Filippo Ugolini, Ludovica Iovino, Selene Attorre, Maria Grazia Giovannini

“…Alterations of astrocytes affect the neurovascular unit, the blood–brain barrier and reverberate to other brain cell populations, favoring or dysregulating their activities. …”
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Effects of Different Inspiratory Muscle Training Protocols on Exercise Capacity, Respiratory Muscle Strength, and Health-Related Quality of Life in Patients with Hypertension by İrem Hüzmeli, Nihan Katayıfçı, Fatih Yalçın, Esra Doğru Hüzmeli

“…Device-guided breathing exercises decreased blood pressure, improved sleep quality, and strengthened respiratory muscles. …”
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Early Serum Heme Oxygenase-1, Soluble Vascular Endothelial Growth Factor Receptor-1, and B-Cell Lymphoma/Leukemia-2 Levels and Unfavorable Obstetric Outcomes by Havva Sutcu, G. Fusun Varol, Cihan Inan, Isil Uzun, N.Cenk Sayin

“…STUDY DESIGN: A total of randomly selected 140 pregnancies were included in this prospective study. Peripheral blood samples were obtained between 110/7 and 136/7 gestational weeks. …”
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Evaluating platelet concentrates by platelet indices, thromboelastography, and flow cytometry by Tapasyapreeti Mukhopadhyay, Arulselvi Subramanian, Venencia Albert, Anand Kumar, Tushar Sehgal, Sulekha Karjee, Harprasad Pati

“…The aim of the study was to assess stored platelet concentrates (PCs) prepared in blood banks for platelet indices, clot strength, and platelet function. …”
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Clinical and Biological Characteristics of Severe Malaria in Children under 5 Years Old in Benin by Xiao Ma, Xin Fan, Kora Chabi Youssaou, Junfei Zhang, Xingyi Wang, Guoqiang Zheng, Shuping Tian, Yujing Gao

“…Inclusion, exclusion, and blood transfusion criteria were identified. Results. …”
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Herbal Medicines as Complementary Therapy for Managing Complications in COVID-19 Patients with Diabetes Mellitus by Adha SA, Afifah NN, Latarissa IR, Iftinan GN, Kusuma ASW, Febriyanti RM, Barliana MI, Lestari K

“…Raya Bandung Sumedang KM. 21, Jatinangor, 45363, Indonesia, Email lestarikd@unpad.ac.idAbstract: Diabetes mellitus (DM) is recognized and classified as a group of conditions marked by persistent high blood glucose levels. It is also an inflammatory condition that may influence concurrent disease states, including Coronavirus Disease 2019 (COVID-19). …”
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Clinical Features and Prevalence of Spondyloarthritis in a Cohort of Italian Patients Presenting with Acute Nongranulomatous Anterior Uveitis by Elena Bolletta, Pierluigi Macchioni, Giorgia Citriniti, Valentina Mastrofilippo, Raffaella Aldigeri, Luca De Simone, Fabrizio Gozzi, Chantal Adani, Anna Sangiovanni, Chiara Posarelli, Michele Figus, Francesco Muratore, Nicolò Pipitone, Carlo Salvarani, Luca Cimino

“…All patients underwent ophthalmic evaluation and blood test with HLA-B27 typing and were referred to a rheumatologist to identify any undiagnosed SpA. …”
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Interactions Between Trace Elements and Macro Minerals in Pregnant Heifers by Raquel S. Dias Betini, Secundino López, Yuri R. Montanholi, James France

“…At the end of the digestibility trial, blood (jugular venipuncture) and liver (biopsy) samples were collected from each heifer. …”
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Rationale, Design, and Baseline Characteristics of Beijing Prediabetes Reversion Program: A Randomized Controlled Clinical Trial to Evaluate the Efficacy of Lifestyle Intervention... by Yingying Luo, Sanjoy K. Paul, Xianghai Zhou, Cuiqing Chang, Wei Chen, Xiaohui Guo, Jinkui Yang, Linong Ji, Hongyuan Wang

“…Parameters relevant to glucose, lipids, blood pressure, lifestyle, and other metabolic markers were similar between conventional and intensive lifestyle intervention group at baseline. …”
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A Case Report of Aicardi-Goutières Syndrome Type 7 Caused by IFIH1 Gene Mutation and a Literature Review by ZHAO Min, SHU Zhou, HAN Tongxin, FU Yanhua, GAO Tianji, MAO Huawei

“…Growth retardation and nervous system involvement are the most prevalent.The condition usually involve the skin, blood system, digestive system, kidney, heart, and other organs. …”
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Effect of Carboxymethyl chitosan-sodium alginate hydrogel loaded with Astragalus membranaceus-Panax notoginseng on wound healing in rats by Jing Li, Jing Li, Linai Li, Yue Yu, Ruixin Qin, Chaoyan Yu, Chen Chen, Youming Dong, Yadong Tan, Yunen Liu, Xuanli Liu

“…In vivo experiments of wound healing on SD rats showed that APCS hydrogels significantly accelerated skin wound healing, reduced inflammatory response, enhanced the formation of blood vessels, granulation tissues, and collagen fibers, and promoted re-epithelialization at the wound site. …”
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Therapeutic effects of mirodenafil, a phosphodiesterase 5 inhibitor, on stroke models in rats by Fred Kim, Padmanabh Singh, Hyunji Jo, Tianyang Xi, Dong-Keun Song, Sae Kwang Ku, Jai Jun Choung

“…Mirodenafil is a phosphodiesterase 5 (PDE5) inhibitor with high specificity for its target and good blood-brain barrier permeability. The drug, which is currently used for treatment of erectile dysfunction, reduces Aβ and pTau levels and improves cognitive function in mouse models of Alzheimer's disease. …”
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NETosis Secondary to the Use of Levamisole-Adulterated Cocaine: A Likely Underlying Mechanism of Vasculopathy by Manuela Osorio, Isabel Velásquez, Ruben Vargas, Adriana Vanegas-García, Mauricio Rojas, Gloria Vásquez, Carlos Muñoz-Vahos

“…Neutrophils were isolated from the peripheral blood of healthy controls by Ficoll-Hystopaque density gradient centrifugation followed by dextran sedimentation. …”
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Randomized Controlled Study Comparing Use of Propofol Plus Fentanyl versus Midazolam Plus Fentanyl as Sedation in Diagnostic Endoscopy in Patients with Advanced Liver Disease by Sameh Abdelkhalik Ahmed, Amal Selim, Nehad Hawash, Ahmed Khaled Tawfik, Mohamed Yousef, Abdelrahman Kobtan, Rehab Badawi, Sally Elnawasany, Reham Abdelkader Elkhouly, Amr Shaaban Hanafy, Fatma H. Rizk, Loai Mansour, Sherief Abd-Elsalam

“…Complication rates were similar in both groups except for mean arterial blood pressure which was significantly lower in group of patients receiving propofol and fentanyl (P=0.001). …”
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Association between Clinical Characteristics and Laboratory Findings with Outcome of Hospitalized COVID-19 Patients: A Report from Northeast Iran by Sahar Sobhani, Reihaneh Aryan, Elham Kalantari, Salman Soltani, Nafise Malek, Parisa Pirzadeh, Amir Yarahmadi, Atena Aghaee

“…Decreased levels of consciousness and dyspnea were statistically more frequent in nonsurvivors (p=0.003 and p=0.011, respectively). Baseline white blood cell (WBC) count, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) were significantly higher in nonsurvivors (p<0.001). …”
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Ethanol-Induced Alterations of T Cells and Cytokines after Surgery in a Murine Infection Model by Nadine Lanzke, Mario Menk, Clarissa von Haefen, Lilit Sargsyan, Bianca Scharf, Klaus-Dieter Wernecke, Claudia D. Spies

“…Bacterial load was determined in lungs and blood. T helper cell subpopulations and the released cytokines were assessed in lungs, spleens, and plasma. …”
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Neutrophils Are Dysregulated in Patients with Hereditary Angioedema Types I and II in a Symptom-Free Period by Tereza Grymova, Marcela Vlkova, Premysl Soucek, Roman Hakl, Jana Nechvatalova, Peter Slanina, Julie Stichova, Jiri Litzman, Tomas Freiberger

“…We assessed the relative mRNA expression of 10 genes related to neutrophil activation using RNA extracted from the peripheral blood neutrophils of 23 HAE patients in a symptom-free period and 39 healthy donors. …”
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