Beneficial Effects of Ursodeoxycholic Acid on Metabolic Parameters and Oxidative Stress in Patients with Type 2 Diabetes Mellitus: A Randomized Double-Blind, Placebo-Controlled Cli... by Biljana Lakić, Ranko Škrbić, Snežana Uletilović, Nebojša Mandić-Kovačević, Milkica Grabež, Mirna Popović Šarić, Miloš P. Stojiljković, Ivan Soldatović, Zorica Janjetović, Anastasija Stokanović, Nataša Stojaković, Momir Mikov

“…UDCA treatment showed a significant reduction in body mass index (p=0.024) and in diastolic blood pressure (p=0.033), compared to placebo. In addition, there was a statistically significant difference in waist circumference in the UDCA group before and after treatment (p<0.05). …”
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Burden of scrub typhus among patients with acute febrile illness attending tertiary care hospital in Chitwan, Nepal by Sangita Thapa, Pradip Hamal, Navin Kumar Chaudhary, Lokendra Bahadur Sapkota, Jaya Prasad Singh

“…This study aims to determine the seroepidemiology of scrub typhus among febrile patients attending Chitwan Medical College Teaching Hospital (CMC-TH), Bharatpur, Nepal.Study design and setting This was a hospital laboratory-based prospective study conducted in CMC-TH (a 750-bed hospital) located in Bharatpur, Chitwan district of Nepal.Participants A total of 1797 patients visiting CMC-TH with acute febrile illness (temperature more than 38°C) were enrolled in this study.Methods A total of 1797 blood samples were collected from patients presenting with acute febrile illness. …”
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The Potential Applications of Stem Cell Conditioned Medium Secretome in Knee Cartilage Regeneration: A Systematic Review by I Gusti Ngurah Wien Aryana, Febyan Febyan, Nyoman Gede Grenata Nanda Ustriyana

“…These injuries lack inherent regeneration mechanisms due to the absence of blood vessels and limited progenitor cell entry. …”
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Characterizations of cytokines and viral genomes in serum of patients with Dabie bandavirus infection by Zefeng Dong, Man Yuan, Yueping Xing, Hongkai Zhang, Qiang Shen

“…We detected and analyzed the cytokine concentrations and viral genomes in the serum samples of these patients to identify the possible causes of the patients’ deaths and to analyze the viral genetic characteristics.MethodsBlood serum specimens were obtained from the 10 individuals with Dabie bandavirus infection in Suzhou City. …”
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Plasma Chemerin Levels Are Increased in ST Elevation Myocardial Infarction Patients with High Thrombus Burden by Ahmet Hakan Ateş, Uğur Arslan, Aytekin Aksakal, Ahmet Yanık, Metin Özdemir, Selim Kul

“…Angiographic characteristics of the patients including thrombolysis in myocardial infarction (TIMI) thrombus and Gensini scores were noted. Blood samples were taken to detect several biochemical markers including plasma chemerin levels at the admission to hospital. …”
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Poly-γ-Glutamic Acid Attenuates Angiogenesis and Inflammation in Experimental Colitis by Munkhtugs Davaatseren, Jin-Taek Hwang, Jae Ho Park, Myung-Sunny Kim, Shuaiyu Wang, Mi Jeong Sung

“…Moreover, γ-PGA significantly attenuated DSS-induced blood vessel densities. Furthermore, γ-PGA attenuated DSS-induced expression of VEGF-A and its receptor, VEGFR2. …”
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Association between Shock Index and Emergency Department Cardiac Arrest by Chao-Tung Chen, Pei-Ming Wang, Chao-Hsin Wu, Chih-Wei Wei, Tai-Lin Huang

“…The shock index (SI) is defined as the ratio of heart rate to systolic blood pressure. It is a tool used for predicting the prognosis of critically ill and injured patients. …”
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The effectiveness of ERCP in managing preoperative complications of choledochal cysts in children and its role in facilitating early surgical intervention by Tian Zhang, Wenjie Wu, Yijun Shu, Hao Weng, Mingzhe Weng, Ying Zhou, Xuefeng Wang

“…There was no significant difference in primary outcomes, such as surgical duration, rate of minimally invasive surgery, conversion to open surgery, intraoperative bleeding volume, intraoperative blood transfusion, postoperative complications, or average length of hospital stay, between the early surgery group (≤2 weeks) and the late surgery group (&gt;2 weeks).ConclusionsERCP was proved to be a safe and effective intervention for alleviating preoperative complications in pediatric patients with choledochal cyst. …”
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A Case of Placental Mesenchymal Dysplasia by Shigeki Taga, Junko Haraga, Mari Sawada, Aya Nagai, Dan Yamamoto, Ryoji Hayase

“…Color doppler revealed little blood flow in the lesion. Magnetic resonance imaging revealed normal fetus and a large multicystic placenta. …”
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A “Catastrophic” Heparin-Induced Thrombocytopenia by D. Barcellona, M. Melis, G. Floris, A. Mameli, A. Muroni, G. Defazio, F. Marongiu

“…The heparin-PF4 immune complex leads to activation of platelets, monocytes, and endothelial cells which release procoagulant proteins and tissue factor with subsequent blood coagulation activation. Case Report. We describe the case of a woman undergone to knee replacement and affected by urosepsis who developed a HIT after exposure to enoxaparin. …”
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Stem Cell Transplantation for Ovarian Cancer Patient with Associated Myelodysplasia After Maintenance Therapy with Olaparib: A Case Report by Linn Z, Gu Z, Wang L, Cai S

“…After two years, she experienced abnormal blood test results, which ultimately led to a diagnosis of myelodysplastic syndrome (MDS), confirmed through a bone marrow biopsy. …”
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Study of factors associated with obesity in patients using antipsychotics in schizophrenia by Vishalakshi Patnam, P Ramya Keerthi, P Ravi Kiran, Dinesh Panati

“…Results: The mean fasting blood sugar level in cases was 33.3 ± 24.2. The mean TC levels were 176.2 ± 15.8. …”
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Reveal the pharmacodynamic substances and mechanism of an edible medicinal plant Rhodiola crenulate in DSS-induced colitis through plasma pharmacochemistry and metabolomics by Yu Peng, Xiaoao Xiao, Tingting Ji, Xinyuan Wang, Yixuan Xu, Jianbo Xiao, Hui Cao, Zhiyong Chen, Huifan Liu, Yuanqing Gao, Hongxun Tao

“…Meanwhile, our results also found 29 constituents absorbed into blood and 8 metabolized absorbable compounds. The decreased flavonoids prototype and the elevated sulfated products of phenols were observed under pathophysiological conditions of colitis. …”
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Investigation of the Molecular Mechanism of Asthma in Meishan Pigs Using Multi-Omics Analysis by Weilong Tu, Hongyang Wang, Yingying Zhang, Ji Huang, Yuduan Diao, Jieke Zhou, Yongsong Tan, Xin Li

“…We investigated asthma pathogenesis in Meishan pigs through transcriptomic and metabolomic analyses of blood samples taken during autumn and winter. Asthma in Meishan pigs is related to inflammation, mitochondrial oxidative phosphorylation, and tricarboxylic acid (TCA) cycle disorders. …”
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Impact of standard and long-lasting ivermectin formulations in cattle and buffalo on wild Anopheles survival on Sumba Island, Indonesia by Kevin C. Kobylinski, Tri B. T. Satoto, Wisnu Nurcahyo, Yudi Ratna Nugraheni, Vincentius A. Testamenti, I Putu B. A. Winata, Yosua L. Pono, Diana Timoria, Piyanan Assawasuwannakit, Mary Chambers, J. Kevin Baird, Joel Tarning, Lorenz von Seidlein, Claus Bøgh

“…Cattle have substantially higher blood-level concentrations of ivermectin compared to buffalo after receiving similar doses, irrespective of formulation. …”
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Mechanism of TGIF1 on glycolipid metabolism disorders in mice with type 2 diabetes by Yuchen Li, Li Tao, Shikai Wang, Fuyan Bai, Liping Zheng, Lijun Hou

“…Introduction Type 2 diabetes (T2D) is a chronic condition characterized by high levels of blood glucose resulting from the inefficiency of insulin. …”
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Risk Factors and Timing of Additional Surgery after Noncurative ESD for Early Gastric Cancer by Kaipeng Duan, Dongbao Li, Dongtao Shi, Jie Pei, Jiayu Ren, Weikang Li, Anqi Dong, Tao Chen, Jin Zhou

“…The early surgery group experienced higher intraoperative blood loss and a longer operation time than the delayed surgery and upfront surgery groups. …”
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Genetic Relationship Analysis of Genus Nomorhamphus from Lindu Lake, Central Sulawesi and Adaptive Responses to Exposure Different Light Wavelengths by Riva Hafidah, Dinar Tri Soelistyowati, Agus Oman Sudrajat, Alimuddin

“…Male and female growth length and gonad maturation were developed faster under green light exposure, while survival rate, blood glucose level, and color quality were not significantly different under different light. …”
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Effect of Omega-3 Fatty Acid on the Fatty Acid Content of the Erythrocyte Membrane and Proteinuria in Patients with Diabetic Nephropathy by Su Mi Lee, Seuk Hee Chung, Yongjin Park, Mi Kyoung Park, Young Ki Son, Seong Eun Kim, Won Suk An

“…In this study, we evaluated the effect of omega-3 FA on proteinuria in diabetic nephropathy patients who are controlling blood pressure (BP) with angiotensin converting enzyme inhibitor (ACEi) or angiotensin II receptor blocker (ARB). …”
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Acute Oral Toxicity, Histopathological Analysis, and Antimalarial Potential of Jatropha tanjorensis Leaf Extracts by Fatima Jumare, Helen Ileigo Inabo, Muhammad Hassan Isa Doko, Gbonjubola Olusesan Adeshina

“…Background: Jatropha tanjorensis is a leafy vegetable widely consumed across Africa and is valued in folk medicine for its reputed blood-replenishing properties. This study aimed to bridge this research gap by assessing the acute oral toxicity, histopathological effects on vital organs, and chemo-suppressive antimalarial activity of J. tanjorensis leaf extracts, offering crucial insights into their therapeutic potential and safety profiles.Methods: Different extracts of J. tanjorensis leaves were obtained by sequential extraction via maceration. …”
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