Synthesis, Characterization, and In Vivo Cytokinome Profile of IL-12-Loaded PLGA Nanospheres by Ryan A. Lacinski, Justin E. Markel, Jabeen Noore, Hillary G. Pratt, Brock A. Lindsey

“…When IL-12-NS was administered in vivo to female BALB/c mice through retroorbital injection, IL-12-NS produced a favorable systemic cytokine profile for tumoricidal activity within the peripheral blood. Whereas IFN-γ nadir occurred at 72 hours, levels recovered quickly and displayed positive correlations postburst out to 25 days postinjection. …”
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Analgesic Effect of Ultrasound-Guided Anterior Quadratus Lumborum Block at the L2 Level in Patients Undergoing Laparoscopic Partial Nephrectomy: A Single-Center, Randomized Control... by Ying He, Mingying Huang, Qiangui Zhong, Huijuan Ni, Zenggui Yu, Xinjian Zhang

“…Comparison of invasive blood pressure (BP) and heart rate (HR) before and after skin incision in group C was statistically significant, but there was no significant difference in group Q. …”
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Tripchlorolide May Improve Spatial Cognition Dysfunction and Synaptic Plasticity after Chronic Cerebral Hypoperfusion by Zhao-Hui Yao, Xiao-li Yao, Shao-feng Zhang, Ji-chang Hu, Yong Zhang

“…Chronic cerebral hypoperfusion (CCH) is a common pathophysiological mechanism that underlies cognitive decline and degenerative processes in dementia and other neurodegenerative diseases. Low cerebral blood flow (CBF) during CCH leads to disturbances in the homeostasis of hemodynamics and energy metabolism, which in turn results in oxidative stress, astroglia overactivation, and synaptic protein downregulation. …”
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Essential Microenvironment for Thymopoiesis is Preserved in Human Adult and Aged Thymus by J. Shiraishi, M. Utsuyama, S. Seki, H. Akamatsu, M. Sunamori, M. Kasai, K. Hirokawa

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Factors Affecting the Presence of Renal Cortical Cysts in Kidney Donors by Sevim Nuran Kuşlu Çiçek, Amil Huseynov

“…Substantial differences were likewise noted in fasting blood glucose, uric acid, creatinine, HbA1c, and glomerular filtration rate (GFR). …”
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P-glycoprotein and/or Histone Deacetylase 2 Regulates Steroid Responsiveness in Childhood Nephrotic Syndrome by Harshit Singh, Narayan Prasad, Durga Prasanna Misra, Akhilesh Kumar Jaiswal, Vikas Agarwal

“…Background: P-glycoprotein (P-gp) overexpression in peripheral blood mononuclear cells (PBMCs) has been reported in patients with steroid-resistant nephrotic syndrome (SRNS). …”
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Local Inflammation in Fracture Hematoma: Results from a Combined Trauma Model in Pigs by K. Horst, D. Eschbach, R. Pfeifer, S. Hübenthal, M. Sassen, T. Steinfeldt, H. Wulf, S. Ruchholtz, H. C. Pape, F. Hildebrand

“…Animals were mechanically ventilated and under ICU-monitoring for 48 h. Blood and fracture hematoma samples were collected during the time course of the study. …”
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Research and Discussion on the Relationships between Noise-Induced Hearing Loss and ATP2B2 Gene Polymorphism by Suhao Zhang, Enmin Ding, Haoyang Yin, Hengdong Zhang, Baoli Zhu

“…A case-control study of 760 Chinese textile workers was conducted to investigate the relationship between ATP2B2 polymorphisms and NIHL susceptibility. Venous blood was collected and questionnaires were conducted by professional physicians. …”
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Metagenomic analysis identifying a polymicrobial pulmonary infection in a non-HIV immunocompromised patient: a case report by Jing Duan, Jie Ding, Yupeng Wei, Yingxin Zhang, Zhiqing You, Ding Li, Chao Chen

“…CT scan revealed diffuse inflammatory and cavernous lung lesion, and blood examination suggested a polymicrobial infection. …”
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Awareness of cardiovascular disease risk and care received among Australian women with a history of hypertensive disorders of pregnancy: a cross-sectional survey by Kaylee Slater, Rachael Taylor, Clare E. Collins, Melinda Hutchesson

“…Regardless of HDP type or SES, women post-HDP were less likely to receive assessment and management of lifestyle CVD risk factors compared to blood pressure. Most women felt supported in managing stress and mental health, but not for managing body weight, smoking and sleep. …”
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Identification of key genes associated with oxidative stress in ischemic stroke via bioinformatics integrated analysis by Gaiyan Li, Yu Cheng, Shanshan Ding, Qianyun Zheng, Lanqiong Kuang, Ying Zhang, Ying Zhou

“…Finally, quantitative PCR (qPCR) was utilized to validate the expression of feature genes with blood specimens. Results A total of 42 key genes related to OS were acquired. …”
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Prevalence and risk factors of hyperuricaemia in non-obese Chinese: a single-centre cross-sectional study by Chengfu Xu, Jinghua Wang, Xinyu Wang, Yishu Chen, Shenghui Chen, Haoliang Zhai

“…Age, waist circumference, estimated glomerular filtration rate, blood urea nitrogen, excessive drinking and fatty liver were associated with hyperuricaemia in both genders.Conclusion The prevalence of hyperuricaemia was 9.4% in non-obese Chinese adults. …”
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The protective role of GLP-1 in neuro-ophthalmology by Sohum Sheth, Aashay Patel, Marco Foreman, Mohammed Mumtaz, Akshay Reddy, Ramy Sharaf, Siddharth Sheth, Brandon Lucke-Wold

“…Emerging evidence indicates some GLP-1RAs can cross the blood-brain barrier and may have neuroprotective effects. …”
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Lutein administration during gestation protects morphine withdrawal-induced on reflexive motor behavior in mice offspring's by Sahand Sariaslani, Shahin Hassanpour, Bita Vazir

“…Following delivery, offspring from each group were chosen to assess behavior and reflexive motor behaviors. Also, blood samples were collected to measure serum antioxidant activity. …”
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Identifying Risk Factors for Secondary Infection Post-SARS-CoV-2 Infection in Patients With Severe and Critical COVID-19 by Mingquan Guo, Mingquan Guo, Menglu Gao, Jing Gao, Tengfei Zhang, Xin Jin, Jian Fan, Qianying Wang, Xin Li, Jian Chen, Zhaoqin Zhu

“…By clinical examination index analysis of patients, combined with the integrative analysis with RNA-seq analysis in the peripheral blood mononuclear cell isolated shortly from initial infection, this study showed that the antibiotic catabolic process and myeloid cell homeostasis were activated while the T-cell response were relatively repressed in those with the risk of secondary infection. …”
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Evaluating lead leaching from uPVC pipes into drinking water: Characterization with SEM-EDX and ICP-OES by Yassin T.H. Mehdar

“…Furthermore, there are many studies about lead exposure and its damage to the kidneys and reproductive system, as well as contributing to elevated blood pressure and hypertension.This study investigates the presence of lead and its leaching rate from some uPVC pipes into drinking water under different conditions of temperature and time. …”
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Antibody in Lymphocyte Supernatant (ALS) responses after oral vaccination with live Shigella sonnei vaccine candidates WRSs2 and WRSs3 and correlation with serum antibodies, ASCs,... by Malabi M Venkatesan, Cassandra Ballou, Shoshana Barnoy, Monica McNeal, Jill El-Khorazaty, Robert Frenck, Shahida Baqar

“…Previously, mucosal immune responses were measured by assaying IgA- and IgG-ASC in peripheral blood mononuclear cells (PBMCs). In this report, the magnitude of the S. sonnei antigen-specific IgA- and IgG-ALS responses was measured and correlated with previously described ASCs, serum antibodies, fecal IgA and vaccine shedding. …”
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Clinical value of serum biomarkers, squamous cell carcinoma antigen and apolipoprotein C-II in follow-up of patients with locally advanced cervical squamous cell carcinoma treated... by Yoko Harima, Takuro Ariga, Yuko Kaneyasu, Hitoshi Ikushima, Sunao Tokumaru, Shigetoshi Shimamoto, Takeo Takahashi, Noriko Ii, Kayoko Tsujino, Anneyuko I Saito, Hiroki Ushijima, Takafumi Toita, Tatsuya Ohno

“…Progression-free survival (PFS) was the primary endpoint, and overall survival (OS), pelvic PFS (PPFS), and distant metastasis-free survival (DMFS) were the secondary endpoints. Blood samples were collected before and 1 month after radiotherapy to measure serum biomarker levels. …”
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Seroprevalence and Risk Factors of Chlamydia abortus Infection in Tibetan Sheep in Gansu Province, Northwest China by Si-Yuan Qin, Ming-Yang Yin, Wei Cong, Dong-Hui Zhou, Xiao-Xuan Zhang, Quan Zhao, Xing-Quan Zhu, Ji-Zhang Zhou, Ai-Dong Qian

“…In the present study, 1732 blood samples, collected from Tibetan sheep between June 2013 and April 2014, were examined by the indirect hemagglutination (IHA) test, aiming to evaluate the seroprevalence and risk factors of C. abortus infection in Tibetan sheep. 323 of 1732 (18.65%) samples were seropositive for C. abortus antibodies at the cut-off of 1 : 16. …”
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Prevalence, Causes, and Factors Associated with Visual Impairment and Blindness among Registered Pensioners in Ghana by Benjamin D. Nuertey, Kwesi Nyan Amissah-Arthur, Joyce Addai, Victor Adongo, Augustine D. Nuertey, Clement Kabutey, Isaac Asimadu Mensah, Richard Bekoe Biritwum

“…(iii) Observation procedures: data were captured through the use of questionnaires, physical examinations including eye examinations, and urine and blood sample analysis. (iv) Main outcome measure: presenting visual impairment and blindness (as defined by the WHO ICD-10 classification). …”
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