Evaluating the effects of chlorhexidine and vitamin c mouthwash on oral health in non-surgical periodontal therapy: a randomized controlled clinical trial by Nurdan Ozmeric, Ayaz Enver, Sila Cagri Isler, Ceren Gökmenoğlu, Merve Topaloğlu, Hilal Selamet, Gökçen Altun, Selin Aykol Sayar

“…This study conducted as a multicenter, randomized, controlled, double-blind, parallel design clinical study. Sixty patients were included, randomly divided into three groups. 1. …”
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A novel multi-scale and fine-grained network for large choroidal vessels segmentation in OCT by Wei Huang, Qifeng Yan, Lei Mou, Yitian Zhao, Wei Chen, Wei Chen, Wei Chen

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Feasibility of Cognitive Training in Combination With Transcranial Direct Current Stimulation in a Home-Based Context (TrainStim-Home): study protocol for a randomised controlled t... by Ulrike Grittner, Agnes Flöel, Rafal Nowak, Friederike Thams, Daria Antonenko, Merle Rocke, Robert Malinowski

“…With this study, we aim to provide evidence for the feasibility and the effects of a multisession home-based cognitive training in combination with tDCS on cognitive functions of healthy older adults.Methods and analysis The TrainStim-Home trial is a monocentric, randomised, double-blind, placebo-controlled study. Thirty healthy participants, aged 60–80 years, will receive 2 weeks of combined cognitive training and anodal tDCS over left dorsolateral prefrontal cortex (target intervention), compared with cognitive training plus sham stimulation. …”
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Reliability and Validity of Visual Estimation in Determining Thorax Rotation Mobility using the Quadruped Lumbar-Locked Position by Katelyn S Whetstone, Kyle A Matsel, Andrew S Patton, Sarah E Gehres, Kate Schwartzkopf-Phifer

“…Bilateral active and passive lumbar-locked thorax rotation mobility was assessed by all raters and categorized as “Unrestricted” (≥50°) or “Restricted” (<50°) while a research assistant simultaneously measured the motion with a digital inclinometer. All raters were blinded to the results. All results were analyzed for intra-rater reliability and agreement…”
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Impact of Hepatic Portal Venous Gas on the Prognosis of Traumatic Out-of-Hospital Cardiac Arrest: A Reason to Consider Terminating Cardiopulmonary Resuscitation by Seok Ran Yeom, Mun Ki Min, Dae Sup Lee, Min Jee Lee, Mo Se Chun, Sung Wook Park, Wook Tae Yang

“…These images were independently reviewed by two emergency medicine physicians with several years of US examination experience who were blinded to all clinical details and outcomes. We evaluated the prognosis of traumatic OHCA by assessing the presence of HPVG using the US. …”
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Popliteal artery aneurysm is a cause that should not be forgotten in acute limb ischemia by Deniz Sarp Beyazpinar, Mehmet Emir Erol

“…All patients who underwent amputation had exclusively undergone embolectomy; no amputations were observed in patients with PAA (p=0.01). Conclusion: Blinded embolectomy may be the first line surgical treatment for ALI but it has higher amputation rates in 1-year follow-up. …”
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Protocol for the impact of machine learning-based clinician decision support algorithims in perioperative care (IMAGINATIVE) in Singapore general hospital : a large prospective ran... by Marcus Ong, Hairil Rizal Abdullah, Ecosse Lamoureux, Elaine Lum, Gek Hsiang Lim, Tan Pei Yi Brenda, Celestine Loh

“…Patients will be randomly assigned in a 1:1 ratio to either the CARES-guided group (unblinded to risk level) or the unguided group (blinded to the risk level). A total of 9200 patients will be enrolled in the study, with the inclusion criteria encompassing individuals aged 21–100 years old undergoing elective surgeries except for neurology and cardiology surgeries at SGH. …”
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Intervention for Social Frailty Focusing on Physical Activity and Reducing Loneliness: A Randomized Controlled Trial by Gen A, Higuchi Y, Ueda T, Hashimoto T, Kozuki W, Murakami T, Ishigami M

“…This study investigates the effects of a multi-component intervention on PA and loneliness in socially frail older adults.Materials and Methods: This single-blind, randomized controlled trial included 64 participants aged ≥ 60 years with social frailty and pre-frailty defined according to Makizako’s Social Frailty Index. …”
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Latent iron deficiency in non-anemic children under five years of age by Qurat ul Ain Riaz, Saima Ahsan, Tanveer Hussain Chaudhary, Abdul Hafeez Soomro, Muhammad Sabir Khan, Shanza Nazish

“…Methods: A descriptive cross-sectional survey was conducted in pediatrics department of –removed for blind review---from August 2020 to February 2021. …”
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Reflection to enhance dental students´ awareness of and comfort with uncertainty – an experimental study by Joséphine Brodén, Helena Fransson, Niklas Vareman, Maria Pigg

“…Students’ statements of uncertainty and comfort were gathered using a developed questionnaire before and after the exercises. The students were blinded to which of the exercises was the intervention. …”
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Combined effects of reflexology massage and respiratory relaxation on pain following chest tube removal in heart surgery patients by Zainab Bahramian, Majid Kazemi, Reza Vazirinejad, Hadi Hasani

“…Methods This was a double-blind randomized clinical trial performed on 140 patients who underwent heart surgery and had a chest tube in Shiraz, Iran. …”
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Development and feasibility of an mHealth intervention for psychoeducational support of Nigerian women diagnosed with breast cancer undergoing chemotherapy: A pilot randomized cont... by Oluwadamilare Akingbade, Ka Yi Hong, Oluwabukola Sharon Ayo, Adetutu Sefinat Alade, Moshood Akinwumi Lawal, Ibironke Elizabeth Somoye, Victoria Adediran, Olamide Sado, Ka Ming Chow

“…<h4>Methods</h4>A multi-centre, assessor-blinded, parallel-group pilot randomised controlled trial (RCT) was conducted at Lagos State University Teaching Hospital (LASUTH) and Lagos University Teaching Hospital (LUTH). …”
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Carbohydrate Restriction During Recovery from High-Intensity–Interval Training Enhances Fat Oxidation During Subsequent Exercise and Does Not Compromise Performance When Combined W... by Camilla Soegaard, Simon Riis, Jesper Friis Mortensen, Mette Hansen

“…Methods: By using a randomized, double-blinded, placebo-controlled, crossover design, 17 female endurance athletes completed 3 experimental blocks. …”
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Molecular Detection and Isolation of Lumpy Skin Disease Virus during an Outbreak in West Hararghe Zone, Eastern Ethiopia by Umer Seid Geletu, Ahmedin Abdurehman Musa, Munera Ahmednur Usmael, Melaku Sombo Keno

“…Skin biopsy samples from 45 animals displaying clinical signs of LSD were inoculated in Vero cell lines because of limited equipment. After three blind passages, all samples developed cytopathic effects (CPEs). …”
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Analgesic Effect of Ultrasound-Guided Anterior Quadratus Lumborum Block at the L2 Level in Patients Undergoing Laparoscopic Partial Nephrectomy: A Single-Center, Randomized Control... by Ying He, Mingying Huang, Qiangui Zhong, Huijuan Ni, Zenggui Yu, Xinjian Zhang

“…The postoperative follower was blinded to the group allocations. All patients received total intravenous anesthesia, the same multimodal analgesic regimen, and rescue analgesia when needed. …”
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Efficacy of Patellar Taping and Electromyographic Biofeedback Training at Various Knee Angles on Quadriceps Strength and Functional Performance in Young Adult Male Athletes with Pa... by Shahnaz Hasan, Asma Alonazi, Shahnawaz Anwer, Azfar Jamal, Suhel Parvez, Faiz Abdulaziz Saleh Alfaiz, Heng Li

“…., 30°, 60°, and 90° of knee flexion) on quadriceps strength and functional performance in people with PFPS were compared in this single-blind randomized controlled parallel trial. Methods. …”
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The Effects of Lutein and Zeaxanthin Supplementation on Brain Morphology in Older Adults: A Randomized, Controlled Trial by Catherine M. Mewborn, Cutter A. Lindbergh, B. Randy Hammond, Lisa M. Renzi-Hammond, L. Stephen Miller

“…The current study examined if one year of supplementation with lutein (L) and zeaxanthin (Z), two nutrients with known antioxidative properties and cognitive benefits, impacted structural brain outcomes in older adults using a double-blind, randomized, placebo-controlled trial design. …”
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Does perioperative electroacupuncture reduce postoperative pain in dogs undergoing ovariohysterectomy? by Celine Iwe, Anika Schiele, Vanessa Passenegg, Daniele Corona, Regula Bettschart-Wolfensberger, Vanessa Heitzmann

“…Pain was evaluated by two blinded and independent anesthetists using the Short Form of the Multimodal Glasgow Composite Pain Scale (mCMPS-SF) before sedation (T0), and three (T3), six (T6), and 24 h (T24) after anesthesia induction.ResultsPostoperative pain scores did not differ significantly between the groups (p = 0.36), but increased significantly three (T3) (p = 0.001) and six (T6) (p = 0.001) hours after surgery compared to before sedation and 24 h postoperative in both groups. …”
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A randomized controlled trial to study the efficacy of 1% vs. 2% lignocaine in topical airway anesthesia in routine bronchoscopy procedures by Danny Prasad, Prince James, Richa Gupta

“…The minimum concentration of lignocaine used during flexible bronchoscopy to prevent uncontrolled coughing is still unclear. This double-blinded, randomized controlled trial compared the efficacy of 1% and 2% lignocaine solutions for topical anesthesia during routine flexible bronchoscopy procedures. …”
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The role of sex, age, and BMI in treatment decisions for knee osteoarthritis: conservative management versus total knee replacement by Fabiola Ojeda, Laura Tío, Francisco Castro-Domínguez, Simone Tassani, Jerome Noailly, Jordi Monfort

“…Methods This case–control study compared patients assigned to TKR versus conservative management, examining subjects aged 60–75 years with radiographically confirmed KOA (Kellgren–Lawrence grades 2–3), with all participants evaluated by blinded clinicians using validated assessment tools including Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Hospital Anxiety and Depression Scale (HADs), Pain Catastrophizing Scale (PCS) and Daily physical activity (DPA) questionnaires. …”
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