Combination Use of Tegafur and Apatinib as First-Line Therapy in Treatment of Advanced Gastric Cancer: A Single-Blinded Randomized Study by Chaofeng Li, Tao Tang, Wenyue Wang

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Efficacy and Safety of a Novel Herbal Medicine in the Treatment of Irritable Bowel Syndrome: A Randomized Double-Blinded Clinical Trial by Ghasem Bordbar, Mohammad Bagher Miri, Mahmoud Omidi, Saeed Shoja, Malihe Akhavan

“…The present study was a randomized double-blind clinical trial with parallel groups in Iran. …”
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Phantom motor execution as a treatment for phantom limb pain: protocol of an international, double-blind, randomised controlled clinical trial by Brian E McGuire, Lina Bunketorp-Käll, Eva Lendaro, Liselotte Hermansson, Helena Burger, Corry K Van der Sluis, Monika Pilch, Katarzyna Kulbacka-Ortiz, Ingrid Rignér, Anita Stockselius, Lena Gudmundson, Cathrine Widehammar, Wendy Hill, Sybille Geers, Max Ortiz-Catalan

“…Here we present the study protocol for an international (seven countries), multicentre (nine clinics), double-blind, randomised controlled clinical trial to assess the effectiveness of PME in alleviating PLP.Methods and analysis Sixty-seven subjects suffering from PLP in upper or lower limbs are randomly assigned to PME or phantom motor imagery (PMI) interventions. …”
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Sex-Related Effects of Adrenergic Drugs on Conditioned Pain Modulation: A Randomized Controlled Cross-Over Double-Blind Trial by Marie-Philippe Harvey, Marie-Chantal Dubois, Philippe Chalaye, Yanick Sansoucy, Serge Marchand

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A randomized double-blind active-controlled clinical trial on the efficacy of topical basil (Ocimum basilicum) oil in knee osteoarthritis by Alireza Askari, Fatemeh Sadat Hasheminasab, Fatemeh Sadat Hasheminasab, Omid Sadeghpour, Mohammad Mehdi Naghizadehd, Seyed Ali Ravansalar, Aida Iraji, Mohammad Hashem Hashempur

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Efficacy and safety of Lutai Danshen Baishao granules for treating female melasma: A randomized, double-blind, placebo-controlled trial by Meiyu Lyu, Yi Yang, Jinlian Liu, Wenting Fei, Min Fu, Yunting Hong, Hongguo Rong, Chun Wang, Linyuan Wang, Jianjun Zhang

“…Methods: A randomized, double-blind, placebo-controlled trial was conducted at the Third Central Hospital of Tianjin, China from March to December 2023. …”
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The effect of Ocimum basilicum on the prevention of postpartum depression symptoms and sleep quality: A triple-blind randomized controlled clinical trial by Monireh Abdi, Elham Rezaei, Mojgan Mirghafourvand, Fatemeh Ebrahimi, Laleh Payahoo, Alireza Shafiei-Kandjani, Solmaz Ghanbari-Homaie

“…This study is designed to assess the effectiveness of basil in preventing postpartum depression (primary outcome) and sleep quality (secondary outcome). Methods: This triple-blind parallel clinical trial (participants, the researcher, and the data analyst were blinded to the assigned interventions) included 78 postpartum women at Taleghani Hospital, Tabriz, Iran, between April 2023 and April 2024. …”
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Deep Learning Approaches for 3D Model Generation from 2D Artworks to Aid Blind People with Tactile Exploration by Rocco Furferi

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The Effect of Synbiotic Supplementation on Self-Reported Aggression in Healthy Adult Men: A Randomized, Double-Blind, Placebo-Controlled Trial by Rahele Sadat Montazeri, Farzad Shidfar, Fatemeh Sadat Hosseini-Baharanchi, Golraste Kholasezadeh

“…The present study aimed to investigate the effect of synbiotic supplementation on self-reported aggression in healthy adult men. Methods: This double-blind randomized controlled clinical trial was conducted on 100 healthy adult men working at Iran University of Medical Sciences. …”
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Effect of Melatonin on Cognitive Function and Sleep in relation to Breast Cancer Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial by Melissa Voigt Hansen, Michael Tvilling Madsen, Lærke Toftegård Andersen, Ida Hageman, Lars Simon Rasmussen, Susanne Bokmand, Jacob Rosenberg, Ismail Gögenur

“…This study reports secondary endpoints from a randomized, double-blind, placebo-controlled trial. Women, 30–75 years, were randomized to 6mg oral melatonin/placebo for 3 months. …”
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Effects of Lactobacillus gasseri OLL2716 on Helicobacter pylori-Associated Dyspepsia: A Multicenter Randomized Double-Blind Controlled Trial by Atsushi Takagi, Hidetaka Yanagi, Hideki Ozawa, Naomi Uemura, Shigemi Nakajima, Kazuhiko Inoue, Takashi Kawai, Toshihiro Ohtsu, Yasuhiro Koga

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Comparison of Clinical Efficacy of Intravenous Acetaminophen with Intravenous Morphine in Acute Renal Colic: A Randomized, Double-Blind, Controlled Trial by Kambiz Masoumi, Arash Forouzan, Ali Asgari Darian, Maryam Feli, Hassan Barzegari, Ali Khavanin

“…The aim of this study was to compare the clinical efficacy of intravenous acetaminophen with intravenous morphine in acute renal colic pain management. In this double-blind controlled trial, patients aged 18–55 years, diagnosed with acute renal colic, who met the inclusion and exclusion criteria, were randomized into two groups. …”
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Hydromorphone reduced the incidence of emergence agitation after adenotonsillectomy in children with obstructive sleep apnea: A randomized, double-blind study by Huang Qiyuan, Chen Yang, Sun Xiaohui, Su Yongwei, Zhou Ruihao, Chen Guo, Zhu Tao

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Effects of high-power pain threshold ultrasound technique in patients with knee osteoarthritis: A single-blind randomized controlled trial by Yomna F. Ahmed, Rania M. Tawfik, Ahmed M. Tawfick, Shimaa T. Abu El Kasem

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Local Vibratory Stimulation for Temporomandibular Disorder Myofascial Pain Treatment: A Randomised, Double-Blind, Placebo-Controlled Preliminary Study by Emanuela Serritella, Giordano Scialanca, Paola Di Giacomo, Carlo Di Paolo

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Local Anesthesia Versus Saddle Block for Open Hemorrhoidectomy: Cost-Analysis From a Randomized, Double Blind Controlled Trial. by Sikakulya, Franck Katembo, Ssebuufu, Robinson, Okedi, Xaviour Francis, Baluku, Moris, Lule, Herman, Kiyaka, Sonye Magugu, Muhumuza, Joshua, Selamo, Fabrice Molen, Bassara, Godefroy Nyenke, Waziri, Musa Abbas, Kithinji, Stephen Mbae, Mugisho, Munyerenkana Leocadie, Byamungu, Pahari Kagenderezo, Munihire, Jeannot Baanitse, Vahwere, Bienfait Mumbere, Kiswezi, Ahmed, Kyamanywa, Patrick

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Diagnostic Accuracy of Periapical Radiography in Detection and Measurement of the External Root Resorption in Primary Molars: A Single-Blind Prospective Clinical Study by Shirin Taravati, Zohreh Balak, Vahid Rakhshan

“…After the extraction, the extent of resorption was directly measured, twice, by third and fourth observers blinded to radiographic estimates. Radiographic errors and absolute errors (mm) were calculated. …”
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Blinding Bilateral Hyperviscosity Retinopathy in a 43-Year-Old Nigerian Male with Lymphoplasmacytic Lymphoma: A Case Report and Management Challenges by Abdulkabir A. Ayanniyi, Uchenna Godswill Ejikeme, Yohanna Tanko, Rilwan C. Muhammad, Obiageli E. Nnodu

“…We report a case of a 43-year-old male who presented with bleeding gums and sudden onset of bilateral blindness but was not on anticoagulants and had no family history of bleeding disorder. …”
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A consort‐guided randomized, blinded, controlled clinical trial on the effects of 6 weeks training on heart rate variability in thoroughbred horses by Emma Santosuosso, Renaud Léguillette, Sierra Shoemaker, Ryan Baumwart, Sierra Temple, Kaneesha Hemmerling, Tessa Kell, Warwick Bayly

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FTACMT study protocol: a multicentre, double-blind, randomised, placebo-controlled trial of faecal microbiota transplantation for autism spectrum disorder by Li Ling, Wei Wei, Li Lin, Li Ke, Ye Chen, Li Ning, Wang Yu, Zhang Xin, Yang Rong, Zhang Xueying, Cui Jiaqu, Chen Qiyi, Qin Huanlong, Du Yasong, Zhao Xiaoxin, Lu Jubao, Lv Xiaoqiong, Ma Chunlian, Chen Shidong, Kuang Guifang, Zhao Dongmei, Fang Shuanfeng, Zhang Xujing, Yang Binrang, Wang Yanxia, Yuan Song, Zhou Xiang, Zhang Beihua, Jiang Lin, Ji Hong, Yan Yinmei, Yan Peihua, Huang Linsheng, Zhang Shaoyi, Ma Chenhuan, Miao Yun, Ling Wenqi, Geng Bojing, Feng Xueying, Li Huilin, Liu Liyan, Wu Weijia, Li Dexin, Jiang Qianru

“…We are undertaking the first-ever multicentre, double-blind, randomised controlled trial of FMT for the treatment of children with both ASD and gastrointestinal symptoms and will assess the feasibility and efficacy outcomes of this strategy.Methods In total, 318 children with both ASD and gastrointestinal symptoms will be enrolled (from 15 hospitals in China) to receive either FMT intervention (n=212) or a placebo (control, n=106). …”
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