Fecal microbiota transplantation to prevent acute graft-versus-host disease: pre-planned interim analysis of donor effect by Swetha Reddi, Liliia Senyshyn, Maryam Ebadi, Daniel Podlesny, Samuel S. Minot, Ted Gooley, Amanda J. Kabage, Geoffrey R. Hill, Stephanie J. Lee, Alexander Khoruts, Armin Rashidi

“…We designed a randomized, double-blind placebo-controlled trial to test whether healthy-donor fecal microbiota transplantation (FMT) early after alloHCT reduces the incidence of severe aGVHD. …”
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Downregulation of the Proinflammatory State of Circulating Mononuclear Cells by Short-Term Treatment with Pioglitazone in Patients with Type 2 Diabetes Mellitus and Coronary Artery... by Andreas Pfützner, Alexander Weise, Elisabeth Pfützner-Riehn, Georg Lübben, Michael Morcos, Efstrathios Karagiannis, Matthias Weber, Thomas Forst

“…Sixty-three patients with well-controlled type 2 diabetes (52 males, 11 females, age (Mean ± SD): 66±7 yrs, disease duration: 6.6±9.6 yrs, HbA1c: 6.7±0.6%) were randomized to additional 45 mg of pioglitazone or placebo to their existing metformin and sulfonylurea therpay for four weeks in a double-blind study design. Protein risk marker levels (hsCRP, MMP-9, MCP-1, etc.) and the expression of NFκB subunits and NFκB-modulated cytokines from isolated peripheral monocyte/macrophages were determined at baseline and endpoint. …”
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Efficacy and safety of LiWei capsule in chronic non-atrophic gastritis with erosions: a randomized controlled trial by Danyang Cui, Xiao Geng, Juan Wang, Xu Han, Zhijun Huang, Miao Jiang, Yang Gong

“…This phase II, multicenter, randomized, double-blind, placebo- and positive-controlled trial enrolled patients diagnosed with CNG with erosions and damp-heat stasis syndrome. …”
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A Comparative Evaluation of Augmented Reality Indoor Navigation versus Conventional Approaches by Tomáš Macháč, Petr Hořejší, Michal Šimon, Andrea Šimerová

“…Their task is to evaluate the user-friendliness and compare the use of a smartphone with an ARNAV app, 2DMAP with visual elements, and variants without wayfinding support "BLIND". User acceptance is validated using a standardized SUS questionnaire. …”
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Seminoma of Testis Masquerading as Orchitis in an Adult with Paraplegia: Proposed Measures to Avoid Delay in Diagnosing Testicular Tumours in Spinal Cord Injury Patients by Subramanian Vaidyanathan, Peter L. Hughes, Paul Mansour, Bakul M. Soni

“…To prevent delay in the diagnosis of testicular tumours in SCI patients, we propose the following measures: (1) patients who develop swelling of the testis should consult a physician as soon as possible for clinical examination; blind antibiotic therapy should be avoided if possible; (2) if clinical examination reveals a hard swelling of the testis and the typical features of acute urinary infection are absent, an ultrasound scan of the scrotum should be performed as soon as possible; (3) in patients with equivocal ultrasound findings, ultrasound-guided, fine-needle aspiration cytology may allow an early diagnosis of testicular malignancy; (4) education of SCI patients and their caregivers is needed to implement these recommendations.…”
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Efficacy and safety of rivaroxaban in preventing venous thromboembolism in postoperative patients with gynecological malignancies: protocol for a randomised controlled open-label t... by Hong Zhou, Fei He, Ting Wei, Shuyi Wu, Jinhua Zhang, Huan Yi

“…The proposed randomised controlled trial (RCT) aims to compare the efficacy and safety of rivaroxaban and enoxaparin in preventing VTE in patients after surgery for gynaecological malignancies and to provide a reference for clinical medication prevention.Methods and analysis This is a single-centre, randomised, controlled, open-label and assessor-blind clinical trial. Patients undergoing surgery for gynaecological malignancies will be randomly assigned in a 1:1 ratio to an oral rivaroxaban study group and a subcutaneous injection enoxaparin control group for anticoagulant prophylaxis. …”
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Deep Tissue Massage and Nonsteroidal Anti-Inflammatory Drugs for Low Back Pain: A Prospective Randomized Trial by Marian Majchrzycki, Piotr Kocur, Tomasz Kotwicki

“…Prospective controlled randomized single blinded trial. Settings. Ambulatory care of rehabilitation. …”
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Tetracyclines in Rheumatoid Arthritis: Dual Anti-Inflammatory and Immunomodulatory Roles, Effectiveness, and Safety Insights by Mislav Radić, Andrej Belančić, Hana Đogaš, Marijana Vučković, Andrea Gelemanović, Andrea Faour, Ivan Vlak, Josipa Radić

“…Clinical trials, including double-blind, placebo-controlled studies, have shown efficacy in reducing RA symptoms, particularly in early and refractory cases. …”
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Evaluation of Chest CT Scan as a Screening and Diagnostic Tool in Trauma Patients with Coronavirus Disease 2019 (COVID-19): A Cross-Sectional Study by Hossein Abdolrahimzadeh Fard, Salahaddin Mahmudi-Azer, Sepideh Sefidbakht, Pooya Iranpour, Shahram Bolandparvaz, Hamid Reza Abbasi, Shahram Paydar, Golnar Sabetian, Mohamad Mahdi Mahmoudi, Masoume Zare, Leila Shayan, Maryam Salimi

“…The CT scans were evaluated in a blinded manner, and the main CT scan features were described and classified into four groups according to RSNA recommendation. …”
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Clinical Effect of Teucrium polium Extract Ointment on Post Pilonidal Sinus Excision Wound Healing: A Randomized Controlled Trial by Reza Hosseinpour, Nuruddin Hosseini, Seyedeh Fatemeh Hekmatzadeh, Saadat Mehrabi, Hossein Sadeghi Mansourkhani, Marita Mohamadshahi

“…Methods: This randomized double-blind clinical trial was conducted from April 2021 to March 2022. …”
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Expression of MMP1, MMP3, and TIMP1 in intervertebral discs under simulated overload and microgravity conditions by Xuanyu Chen, Zhangfu Li, Chao Zheng, Ji Wu, Yong Hai

“…Methods Overload was simulated using an animal centrifuge, and microgravity was mimicked through tail suspension. A randomized single-blind method was applied to divide 120 age- and weight-matched New Zealand white rabbits into six groups: control groups (30 d, 60 d, 90 d) and overload/microgravity groups (30 d, 60 d, 90 d), with 20 rabbits per group. …”
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Sex-specific associations of prenatal Chinese famine exposure with cataract risk at age sixty: a cross-sectional study by Yuanyou Xia, Xiaoyang Xu, Siyao Wang

“…Abstract Background Age-related cataract (ARC) is among the most common blinding eye disorders among the elderly. Prenatal nutrition may cause irreversible damage to the development of the ocular crystalline lens. …”
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Provision and delivery of survivorship care for adult patients with haematological malignancies: A scoping review protocol. by Zoe-Anne V Baldwin, Steph Busby, David Allsup, Judith Cohen, Olufikayo Bamidele

“…Papers' titles, abstracts, and full text will predominantly be screened by one reviewer with a second reviewer blind screening a proportion. Data will be extracted using a customised table developed in collaboration with the review team, and presented in tabular and narrative format, arranged thematically. …”
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Quality of Abstracts Reporting in Periodontal Randomized Controlled Trials: A Descriptive Analysis by Fahad Alharbi, Khalid Gufran, Muzammil M. Ahmed, Rawda O. Alghabban, Mohammad Meish Almohammadi, Abdullah S. Almutairi

“…There has been no discernible progress over the years, notably in terms of blinding, the randomization description, and the disclosure of potential harms.…”
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Harm reduction strategies in acute care for people who use alcohol and/or drugs: A scoping review. by Daniel Crowther, Janet Curran, Mari Somerville, Doug Sinclair, Lori Wozney, Shannon MacPhee, Annette Elliott Rose, Leah Boulos, Alexander Caudrella

“…A variety of intervention modalities including pharmacological, decision support, safer consumption, early overdose detection and turning a blind eye were identified. Reported outcome measures related to safer use, managed use, and conditions of use. …”
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Development and pilot testing of a nurse-led common-sense model of self-regulation-based heart failure self-care program by Zehao Huang, Sek Ying Chair

“…The pilot study utilized a single-blinded, two-arm, parallel group, randomized controlled trial (RCT) design, adhering to the CONSORT Statement. …”
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In vivo mitochondrial ATP production is improved in older adult skeletal muscle after a single dose of elamipretide in a randomized trial. by Baback Roshanravan, Sophia Z Liu, Amir S Ali, Eric G Shankland, Chessa Goss, John K Amory, H Thomas Robertson, David J Marcinek, Kevin E Conley

“…Here, we describe the impact of a first-in-class cardiolipin-binding compound that is targeted to mitochondria and improves oxidative phosphorylation capacity (Elamipretide, ELAM) in a randomized, double-blind, placebo-controlled clinical trial.<h4>Methods</h4>Non-invasive magnetic resonance and optical spectroscopy provided measures of mitochondrial capacity (ATPmax) with exercise and mitochondrial coupling (ATP supply per O2 uptake; P/O) at rest. …”
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Pericapsular nerve group (PENG) block versus supra-inguinal fascia iliaca (SIFI) block for functional outcome in patients undergoing hip surgeries – A randomised controlled study by Tanusha Saini, Meenakshi Aggarwal, Udeyana Singh, Mirley Rupinder Singh

“…Methods: In this single-centre, double-blinded, randomised trial, 60 patients undergoing hip surgeries under subarachnoid block were randomised into either Group P (PENG block) or Group S (SIFI block). …”
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The Effect of FourWeeks of Beta-Alanine Supplementationon Anaerobic Power and Plasma Lactate Level in Unprofessional Male Bodybuilders by Mahdi Rezagholizadeh

“…For this purpose, the study plan was performed as pretest-posttest with control group and as one blind trial. 20 mature and unprofessional athletes were randomly divided into two groups of 10 people including supplement and placebo (supplement group: 25±0.81 years old, weight 82.10kg±4.78 kg and BMI 24.34±2.19kg/m2 and placebo group: 24.40± 1.07 years old, weight 80.60±5.85 kg and BMI 23.34±1.16 kg/m2). …”
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Factors associated with lingual tonsil hypertrophy in Canadian adults by Matthew S. Harris, Brian W. Rotenberg, Kathryn Roth, Leigh J. Sowerby

“…These were graded for LTH and Reflux Finding Scale (RFS) by blinded examiners. Statistical analysis was performed by comparing the mean LTH value to the variables of interest using two-tailed T-test. …”
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