Effects of Tocotrienol on Cardiovascular Risk Markers in Patients With Chronic Kidney Disease: A Randomized Controlled Trial by Liana Trugilho, Lívia Alvarenga, Ludmila Cardozo, Bruna Paiva, Jessyca Brito, Isis Barboza, Jonatas Almeida, Juliana dos Anjos, Pramod Khosla, Marcelo Ribeiro-Alves, Denise Mafra

“…Tocotrienols, isomers of vitamin E, may provide an effective nutritional strategy to mitigate common cardiovascular risks such as dyslipidemia, inflammation, and oxidative stress in patients with chronic kidney disease (CKD). This double-blind, placebo-controlled, randomized clinical trial aimed to evaluate the effects of a tocotrienol-rich fraction (TRF) supplementation (300 mg/day) on oxidative stress and inflammatory markers, including transcription factors in nondialysis (ND) and hemodialysis (HD) CKD patients for three months. …”
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A novel proficiency test to assess the animal diagnostic investigation process in identifying an unknown toxicant by Andriy Tkachenko, Yang Chen, Marissa Petrey, Scott Fritz, Tim Walsh, David Rotstein, Megan R. Miller, Bruce Williams, Michael Dark, Matthew Kmet, Ravinder Reddy, Gregory Tyson, Sarah M. Nemser

“…In a typical chemistry PT, blind-coded samples are sent to participants for analysis of specific chemical agents, and results are compared to a pre-determined key (e.g., expected concentrations) to assess proficiency. …”
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The Effects of Ankle Joint Position on Deep Peroneal Nerve Latencies by Mohamed Hussein El-Gendy, Mahmoud Salah Abd El-Fattah, Mohamed Magdy El Meligie, Efrem Kentiba, Yasser Ramzy Lasheen

“…These findings provide preliminary evidence that may help optimize ankle positioning in electrodiagnostic testing. Further blinded research with larger, more diverse samples is warranted. …”
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Effects of Intraoperative Dexamethasone and Ondansetron on Postoperative Nausea and Vomiting in Microvascular Decompression Surgery: A Randomized Controlled Study by Cattleya Thongrong, Patitha Chullabodhi, Pornthep Kasemsiri, Amnat Kitkhuandee, Narin Plailaharn, Lumyai Sabangban, Thirada Jimarsa

“…A prospective, double-blinded, randomized control trial was conducted with 54 patients who underwent MVD. …”
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n-3 Polyunsaturated Fatty Acid Supplementation Has No Effect on Postprandial Triglyceride-Rich Lipoprotein Kinetics in Men with Type 2 Diabetes by André J. Tremblay, Benoît Lamarche, Jean-Charles Hogue, Patrick Couture

“…Dietary n-3 polyunsaturated fatty acids (PUFAs) have been proposed to modulate plasma lipids, lipoprotein metabolism, and inflammatory state and to reduce triglyceride (TG) concentrations. The present double-blind, randomized, placebo-controlled, crossover study investigated the effects of n-3 PUFA supplementation at 3 g/d for 8 weeks on the intravascular kinetics of intestinally derived apolipoprotein (apo) B-48-containing lipoproteins in 10 men with type 2 diabetes. …”
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Examining the effect of salbutamol use in ozone air pollution by people with exercise‐induced bronchoconstriction by Bennett T. Stothers, Andy Hung, Patric E. O. Gonçalves, Lulu X. Pei, Tessa van deKerkhof, Jem I. Arnold, Owen D. Harris, Nadine Borduas‐Dedekind, Andrew W. Sheel, Michael S. Koehle

“…We conducted a double‐blind, randomized, placebo‐controlled crossover study including 18 subjects diagnosed with EIB by a eucapnic voluntary hyperpnea (EVH) test. …”
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Non-pharmacological therapies in the treatment of chemotherapy-induced alopecia – a literature review by Izabela Ochonska, Karolina Jaglarz, Maciej Kuca, Marcin Cholewa, Maria Jasiewicz

“…Data for this paper were gathered using electronic databases like PubMed and Google Scholar, with a focus on papers from the last five years, particularly clinical trials, double-blind randomized studies, meta-analyses, and reviews. …”
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A Deep Learning Approach to Classify Fabry Cardiomyopathy from Hypertrophic Cardiomyopathy Using Cine Imaging on Cardiac Magnetic Resonance by Wei-Wen Chen, Ling Kuo, Yi-Xun Lin, Wen-Chung Yu, Chien-Chao Tseng, Yenn-Jiang Lin, Ching-Chun Huang, Shih-Lin Chang, Jacky Chung-Hao Wu, Chun-Ku Chen, Ching-Yao Weng, Siwa Chan, Wei-Wen Lin, Yu-Cheng Hsieh, Ming-Chih Lin, Yun-Ching Fu, Tsung Chen, Shih-Ann Chen, Henry Horng-Shing Lu

“…Additionally, a single-blinding study and external testing using data from the Taichung Veterans General Hospital (TCVGH) demonstrated the reliability and effectiveness of the model, achieving an F1-score of 0.727, an accuracy of 0.806, and an AUC of 0.918, demonstrating the model’s reliability and usefulness. …”
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External quality assurance of chest X-ray interpretation to strengthen diagnosis of childhood TB by B.F. Melingui, E. Leroy-Terquem, J.V. Taguebue, T.C. Eap, L. Borand, C. Khosa, R. Moh, J. Mwanga-Amumpaire, S. Beneteau, M.T. Eang, I. Manhiça, A. Mustapha, O. Marcy, E. Wobudeya, P.Y. Norval, M. Bonnet, on behalf of the TB-Speed study group

“…METHODS: Every quarter, TB suggestive or unreadable CXRs and 10% of remaining CXRs from children with presumptive TB were selected for blind re-reading by national re-readers. The proportion of CXRs selected for EQA and re-read assessed the uptake. …”
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Influence of Dapagliflozin on Glycemic Variations in Patients with Newly Diagnosed Type 2 Diabetes Mellitus by Feng-fei Li, Gu Gao, Qian Li, Hong-hong Zhu, Xiao-fei Su, Jin-dan Wu, Lei Ye, Jian-hua Ma

“…This was a randomized, double-blind, placebo-controlled, phase 3 trial. A total of 28 patients with newly diagnosed T2DM with HbA1c levels of 7.5–10.5% were randomly selected to receive dapagliflozin or placebo treatment for 24 weeks. …”
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Astronomaly Protege: Discovery through Human-machine Collaboration by Michelle Lochner, Lawrence Rudnick

“…This provides important advantages over similarity searches, which can only find more examples of known sources, or blind anomaly detection, which selects unusual but not necessarily scientifically interesting sources. …”
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The Safety and Tolerability of 5-Aminolevulinic Acid Phosphate with Sodium Ferrous Citrate in Patients with Type 2 Diabetes Mellitus in Bahrain by Feryal Al-Saber, Waleed Aldosari, Mariam Alselaiti, Hesham Khalfan, Ahmed Kaladari, Ghulam Khan, George Harb, Riyadh Rehani, Sizuka Kudo, Aya Koda, Tohru Tanaka, Motowo Nakajima, Abdulla Darwish

“…This prospective, randomized, single-blind, placebo-controlled, dose escalating pilot clinical trial assessed the safety of 5-ALA with SFC at doses up to 200 mg 5-ALA/229.42 mg SFC per day in patients living in Bahrain with type 2 diabetes mellitus that was uncontrolled despite the use of one or more antidiabetic drugs. …”
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The utility of artificial intelligence in identifying radiological evidence of lung cancer and pulmonary tuberculosis in a high-burden tuberculosis setting by Z Z Nxumalo, E M Irusen, B W Allwood, M Tadepalli, J Bassi, C F N Koegelenberg

“…These chest radiographs were de-identified and randomly uploaded by a blinded investigator into qXR software. The output was generated as probability scores from predefined threshold values. …”
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Comparison of the Efficacy between Bilateral Ultrasound Guided Erector Spinae Block versus Incision Site Infiltration for Duration of Analgesia in Lumbar Spinal Surgery Using Levob... by Karthik G Sheshadri, Sudheer Ramegowda, Mahesh Chandra, Prajyot Bhurli, Ashwani Kristipati, Renjan R I

“…Methods: A prospective randomized single blinded study was carried out in 50 patients of ASA grade I and II, aged 20 to 60 years scheduled for elective lumbar spine surgeries. …”
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Extracorporeal Shock Waves Therapy for the Treatment of Acute and Chronic Wounds—A Prospective, Monocentric Clinical Trial to Examine the Effect of Shock Waves on Wound Healing by Kristina Landscheidt, Ahmed Alabdulmohsen, Markus Hübscher, Benjamin Geber, Jochen‐Frederick Hernekamp, Ole Goertz

“…ABSTRACT Introduction The aim of our prospective blinded clinical study was to examine a possible improvement and acceleration of epithelialization by treatment with low‐energy extracorporeal shock waves on skin graft donor and recipient sites in patients with chronic wounds. …”
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The relationship between malocclusion and speech patterns: a cross-sectional study by Nada E. Tashkandi, Razan AlDosary, Hissah Zamandar, Misk Alalwan, Mohannad Alwothainani, Hissah Aljoaid, Duaa Alghazhmri, Eman Allam, Anand Marya, Samar M. Adel

“…A standard speech sample was recorded for each subject and evaluated by a blinded speech therapist to judge misarticulations and indicate the misarticulation classification. …”
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3D laser structuring of supermetalphobic microstructures inside elastomer for multilayer high-density interconnect soft electronics by Chengjun Zhang, Qing Yang, Haoyu Li, Zexiang Luo, Yu Lu, Jialiang Zhang, Cheng Li, Feng Chen

“…FLDW technology, with the characteristics of high spatial resolution and high precision, allows the maskless fabrication of high-resolution embedded LM microchannels and high-density vertical interconnect accesses for 3D integrated circuits. High-aspect-ratio blind/through LM microstructures are formed inside the elastomer due to the supermetalphobicity induced during laser ablation. …”
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Maternal singing and speech have beneficial effects on preterm infant’s general movements at term equivalent age and at 3 months: an RCT by Manuela Filippa, Gianluca Filippa, Elisa Della Casa, Alberto Berardi, Odoardo Picciolini, Sara Chiara Meloni, Clara Lunardi, Alessandra Cecchi, Alessandra Sansavini, Luigi Corvaglia, Luigi Corvaglia, Didier Grandjean, EVC Group, Fabrizio Ferrari

“…GMs were recorded both before and after the intervention – which took place at term equivalent age – and again at 3 months corrected age. The GMs were blindly coded based on the muted video tracks to produce both a general score and a detailed score.ResultsBefore the intervention, there were no significant differences between the two groups. …”
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Clinical Outcome between Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndrome and Diabetes by Peixun He, Xiaolin Luo, Jiabei Li, Yi Li, Xiaozeng Wang, Lan Huang, Jun Jin, Yaling Han

“…The study was a single-center, prospective, randomized, open-label, blinded endpoint, and controlled registry trial. A total of 270 ACS patients with diabetes were randomly assigned in a 1 : 1 ratio to either the ticagrelor group or the clopidogrel group. …”
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Paramedic Recognition of Sepsis in the Prehospital Setting: A Prospective Observational Study by Robert S. Green, Andrew H. Travers, Edward Cain, Samuel G. Campbell, Jan L. Jensen, David A. Petrie, Mete Erdogan, Gredi Patrick, Ward Patrick

“…Paramedic identification of sepsis was assessed using a novel prehospital sepsis screening tool developed by the study team and compared to blind, independent documentation of ED diagnoses by attending emergency physicians (EPs). …”
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