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541
Enhancing ophthalmology education through a mobile flipped classroom: a new teaching method
Published 2025-01-01“…Abstract Objective Glaucoma is a major cause of irreversible blindness globally. Optical coherence tomography (OCT) aids early glaucoma diagnosis. …”
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542
An Update on the Genetics of Usher Syndrome
Published 2011-01-01“…It is clinically and genetically heterogeneous and is the most common cause underlying deafness and blindness of genetic origin. Clinically, USH is divided into three types. …”
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543
Enhanced ferroptosis sensitivity promotes the formation of highly myopic cataract via the DDR2-Hippo pathway
Published 2025-02-01“…Abstract Highly myopic cataract (HMC) is a leading cause of blindness among the working-age individuals, with its pathogenesis poorly understood. …”
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544
Retinitis Pigmentosa and Bilateral Idiopathic Demyelinating Optic Neuritis in a 6-Year-Old Boy with OFD1 Gene Mutation
Published 2017-01-01“…The patient had a history of night blindness, a mottled retina without pigmentation, extinguished electroretinographic response, tritanopia, and an absent ellipsoid zone outside the macula fovea by optical coherence tomography in both eyes. …”
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545
Detection of Diabetic Retinopathy Using a Multi-Decision Inception-ResNet-Blended Hybrid Model
Published 2025-01-01“…Diabetic retinopathy (DR) is a severe complication of diabetes that affects the retinal structures and can lead to significant visual impairment or even blindness. Early diagnosis is crucial for reducing and preventing the progression of this condition. …”
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546
Epidemiological characterization of primary open-angle glaucoma
Published 2010-11-01“…It is a silent and slowly progressive disease leading to blindness. In most patients this can be prevented if the risk factors leading to the disease are detected in time. …”
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547
QuantumNet: An enhanced diabetic retinopathy detection model using classical deep learning-quantum transfer learning
Published 2025-06-01“…The method is as follows: • Evaluate three classical deep learning models—CNN, ResNet50, and MobileNetV2—using the APTOS 2019 blindness detection dataset on Kaggle to identify the best-performing model for integration. • QuantumNet combines the best-performing classical DL model for feature extraction with a variational quantum classifier, leveraging quantum transfer learning for enhanced diagnostics, validated statistically and on Google Cirq using standard metrics. • QuantumNet achieves 94.11 % accuracy, surpassing classical DL models and prior research by 11.93 percentage points, demonstrating its potential for accurate, efficient DR detection and broader medical imaging applications.…”
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548
Clinical-epidemiological behaviour of patients after cataract surgery
Published 2010-12-01“…<p><strong>Background:</strong> Cataract is the leading cause of blindness in the world. Its only effective treatment is surgery, with a high rate of efficiency, but it is not always practiced due to several reasons that limit access to health services.…”
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549
Predict Diabetes Using Voting Classifier and Hyper Tuning Technique
Published 2023-01-01“…Today, diabetes is one of the most common chronic diseases in the world due to the people’s sedentary lifestyle which led to many health issues like heart attack, kidney frailer and blindness. Additionally, most of the people are unrealizable about the early-stage diabetes symptoms to prevent it. …”
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550
Association of sildenafil use with age-related macular degeneration: a retrospective cohort study
Published 2024-04-01“…Objective Despite significant advances in clinical care and understanding of the underlying pathophysiology, age-related macular degeneration (AMD)—a major cause of global blindness—lacks effective treatment to prevent the irreversible degeneration of photoreceptors leading to central vision loss. …”
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551
Morroniside Ameliorates Endotoxin-Induced Uveitis by Regulating the M1/M2 Polarization Balance of Macrophages
Published 2023-01-01“…Uveitis is a condition characterized by the inflammation of the uvea and ocular tissues that causes extreme pain, decreases visual acuity, and may eventually lead to blindness. The pharmacological functions of morroniside, isolated from Cornus officinalis, are multifarious. …”
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552
A clinical practical model for preoperative prediction of visual outcome for pituitary adenoma patients in a retrospective and prospective study
Published 2024-12-01“…Logistic regression selected three clinical features: blindness, headache, and visual impairment course. …”
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553
Determinants of Intraocular Pressure (IOP) of Glaucoma Patients at Felege Hiwot Referral Hospital, Bahir Dar, Ethiopia
Published 2021-01-01“…Glaucoma is a leading cause of irreversible blindness in the world associated with characteristic damage to the optic nerve and patterns of visual field loss due to retinal ganglion cell degeneration. …”
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554
NLRP3 Inflammasome: Activation and Regulation in Age-Related Macular Degeneration
Published 2015-01-01“…Age-related macular degeneration (AMD) is the leading cause of legal blindness in the elderly in industrialized countries. …”
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555
Rho-Kinase/ROCK as a Potential Drug Target for Vitreoretinal Diseases
Published 2017-01-01“…Vitreoretinal diseases including diabetic retinopathy, age-related macular degeneration, and proliferative vitreoretinoapthy are still a major cause of blindness. While anti-VEGF therapy has recently been widely used for vitreoretinal disorders due to its efficacy, attention has been drawn to new unmet needs. …”
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556
Cyanin Chloride Inhibits Hyperbaric Pressure-Induced Decrease of Intracellular Glutamate-Aspartate Transporter in Rat Retinal Müller Cells
Published 2018-01-01“…Glaucoma is the leading cause of irreversible blindness throughout the world. The pathogenesis of glaucoma is complex, and neuroprotection is a crucial aspect of therapy. …”
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557
A 14-Year Retrospective Analysis of Endogenous Endophthalmitis in a Tertiary Referral Center of Southern Thailand
Published 2020-01-01“…Despite full treatment coverage, visual prognosis was extremely poor and the rates of blindness and evisceration/enucleation were still high.…”
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558
The negative off-response driven by M-cone and depolarizing bipolar cell in the rat electroretinogram
Published 2025-02-01“…Furthermore, the ON/OFF responses of other two types of mutation rats, the middle-wavelength opsin cone dysfunction (MCD) rats and congenital stationary night blindness (CSNB) rats, were recorded. Typical scotopic and photopic ON/OFF responses were recorded in SD rats. …”
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559
Differentially Expressed MicroRNAs in the Development of Early Diabetic Retinopathy
Published 2017-01-01“…The pathological mechanisms of diabetic retinopathy (DR), a leading cause of blindness in adults with diabetes mellitus, remain incompletely understood. …”
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560
Blockade of Vascular Endothelial Growth Factor Receptor 1 Prevents Inflammation and Vascular Leakage in Diabetic Retinopathy
Published 2015-01-01“…Diabetic retinopathy (DR) is a leading cause of blindness in working age adults. The objective of this study is to investigate the effects of vascular endothelial growth factor receptor 1 (VEGFR1) blockade on the complications of DR. …”
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