Effects of Meaningful Action Observation Therapy on Occupational Performance, Upper Limb Function, and Corticospinal Excitability Poststroke: A Double-Blind Randomized Control Trial by Aryan Shamili, Afsoon Hassani Mehraban, Akram Azad, Gholam Reza Raissi, Mohsen Shati

“…Both assessors of clinical and neurophysiological outcomes were blinded to the allocation of subjects. Result. Finally, the results of outcomes in 24 patients who completed the study were analyzed. …”
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Influence of Lidocaine including Buprenorphine for Postoperative Analgesia after the Extraction of Mandibular Third Molars: A Randomized Controlled, Double-Blind, Split-Mouth Study by Nimrat K. Jawanda, Anand Shukla, Anupam Singh, Kalyana C. Pentapati, Srikanth Gadicherla

“…We conducted a randomized, double-blinded, split-mouth trial among 21 patients with impacted mandibular third molars bilaterally. …”
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Double-blind, randomized, placebo-controlled pilot clinical trial with gamma-band transcranial alternating current stimulation for the treatment of schizophrenia refractory auditory hallucinations by Xiaojuan Wang, Xiaochen Zhang, Yuan Chang, Jingmeng Liao, Shuang Liu, Dong Ming

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Efficacy and safety of jaktinib hydrochloride tablets in active axial spondyloarthritis: a multicentre, randomised, double-blind, placebo-controlled phase II clinical trial by Xiaomei Li, Xiaoxia Wang, Jian Wu, Xiao Zhang, Chunde Bao, Shengqian Xu, Lingyun Sun, Juan Wang, Guixiu Shi, Xiaofei Wang, Qing Dai, Antao Xu, Huaxiang Wu, YongQing Wang, Yan Ye, Yongfu Wang, Huaxiang Liu, Chenyin Lv, Jun Miao, Weiqi Min, Kuanting Wang, Luan Xue, Shanhui Ye

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The Effect of Zinc Supplementation on Glycemic, Weight, and Blood Pressure Control in Patients With Type 2 Diabetes Mellitus: A Double‐Blind Randomized Controlled Trial by Mehrab Sayadi, Sara Javadpour Nowbandegani, Fatemeh Balaghi Inalou, Bahman Nazemzadegan, Shirzad Javidi Alsaadi, Mohammadreza Eskandari, Matin Sepehrinia

“…Methods In this randomized controlled double‐blind trial, 79 patients with Type 2 diabetes were allocated into two groups through permuted block randomization method. …”
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Pre-IVF treatment with a GnRH antagonist in women with endometriosis (PREGNANT): study protocol for a prospective, double-blind, placebo-controlled trial by Hugh Taylor, Hao Huang, Lubna Pal, Heping Zhang, Howard J Li, Sandra Carson, Valerie Flores, Jared Robbins, Nanette F Santoro, James H Segars, David Seifer, Steven Young

“…There have been no studies on the efficacy of GnRH antagonists for the treatment of endometriosis-related infertility.Methods and analysis This study is a multicentre, prospective, randomised, double-blind, placebo-controlled trial to study the efficacy of GnRH antagonist pretreatment for women with endometriosis who are undergoing IVF. …”
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Does candidate race influence simulated patient ratings in standardised assessments of clinical practice? A single-blinded randomised study in UK medical schools by Celia Brown, Amir H Sam, Rachel Westacott, Mark Gurnell, Sarah Khavandi, Malcolm Reed, Ann Sebastian, Kerry Badger

“…This study aimed to determine whether being a non-white candidate affected scoring by simulated patients, compared with a white candidate, at three different performance grades in the same history-taking station.Design Single-blinded, video-based, randomised study.Participants 163 simulated patients watched a randomly allocated set of six videos. …”
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Analgesic Characteristics of Bupivacaine Alone and in Combination with Dexmedetomidine or Meperidine in Spinal Anesthesia during Cesarean Section: A Double-Blind Randomized Clinical Trial Study by Simin Azemati, Amir Zarghami, Reza Jouybar, Vida Naderi-boldaji

“…Methods. In this double-blind randomized clinical trial study, ninety pregnant women were divided into groups to receive 10 mg bupivacaine (group B), 10 mg bupivacaine with 5 μg dexmedetomidine (group BD), or 10 mg bupivacaine with 10 mg meperidine (group BM) intrathecal. …”
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Immunogenicity and safety of a COVID-19 DNA vaccine in healthy adults and elderly: A randomized, observer-blind, placebo-controlled phase 2 trial by Siyue Jia, Chengwei Shao, Xin Cheng, Hongxing Pan, Zhijian Wang, Yu Xia, Jianfang Xu, Xuefen Huai, Danjing Leng, Jiarong Wang, Gan Zhao, Bin Wang, Jingxin Li, Fengcai Zhu

“…We conducted a randomized, observer-blind, placebo-controlled phase 2 trial of intradermal injection of INO-4800 in both healthy adults and elderly individuals. …”
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Gabapentin versus Transdermal Fentanyl Matrix for the Alleviation of Chronic Neuropathic Pain of Radicular Origin: A Randomized Blind Multicentered Parallel-Group Noninferiority Trial by Chang Ju Hwang, Jae Hyup Lee, Jung-Hoon Kim, Sang Hyuk Min, Kun-Woo Park, Hyoung-Yeon Seo, Kwang-Sup Song

“…The study was designed as a randomized blind multicentered parallel-group noninferiority trial. …”
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Evaluation of Clinical Effectiveness and Subjective Satisfaction of a New Toothbrush for Postsurgical Hygiene Care: A Randomized Split-Mouth Double-Blind Clinical Trial by Marco Montevecchi, Annalisa Moreschi, Maria Rosaria Gatto, Luigi Checchi, Vittorio Checchi

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Safety, Tolerability, and Pharmacokinetics of NIM‐1324 an Oral LANCL2 Agonist in a Randomized, Double‐Blind, Placebo‐Controlled Phase I Clinical Trial by Andrew Leber, Raquel Hontecillas, Nuria Tubau‐Juni, Josep Bassaganya‐Riera

“…Oral NIM‐1324 was assessed for safety, tolerability and PK in normal healthy volunteers in a randomized, double‐blind, placebo‐controlled trial. Subjects (n = 57) were randomized into five single ascending dose (SAD) cohorts (250, 500, 750, 1000, 1500 mg, p.o.) and three multiple ascending dose (MAD) cohorts (250, 750, 1500 mg QD for 7 days, p.o.). …”
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Analgesic Efficacy of Intravenous Ibuprofen in the Treatment of Postoperative Acute Pain: A Phase III Multicenter Randomized Placebo-ControlledDouble-Blind Clinical Trial by Hong-Su Zhou, Ting-Ting Li, Yu Pi, Ting-Hua Wang, Fei Liu, Liu-Lin Xiong

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A New Technique in Primary Repair of Congenital Esophageal Atresia Preventing Anastomotic Stricture Formation and Describing the Opening Condition of Blind Pouch: Plus (“+”) Incision by Mehmet Melek, Ufuk Cobanoglu

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Effect of Ondansetron on the Occurrence of Hypotension and on Neonatal Parameters during Spinal Anesthesia for Elective Caesarean Section: A Prospective, Randomized, Controlled, Double-Blind Study by Walid Trabelsi, Chihebeddine Romdhani, Haythem Elaskri, Walid Sammoud, Mohamed Bensalah, Iheb Labbene, Mustapha Ferjani

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Safety and efficacy of oral administrated cepharanthine in non-hospitalized, asymptomatic or mild COVID-19 patients: a Double-blind, randomized, placebo-controlled trial by Jianyi Wei, Shupeng Liu, Yuexiang Bian, Lei Li, Biyun Qian, Zixuan Shen, Yan Zhang, Adila Abuduaini, Fuchen Dong, Xin Zhang, Jinhui Li, Yongpei Yu, Weituo Zhang, Jun Wang, Wei Zhai, Qixiang Song, Yu Zheng, Weihua Pan, Lanlan Yu, Qimin Zhan, Ning Zhang, Junhua Zheng, Shuming Pan, Chen Yao, Hai Li

“…To evaluate the efficacy and safety of CEP compared with placebo in adults with asymptomatic or mild coronavirus disease 2019 (COVID-19), we conducted a proof-of-concept, double-blind, randomized, placebo-controlled trial. Patients were randomized to receive 120 mg/day of CEP, 60 mg/day CEP or placebo for 5 days. …”
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Effectiveness of clove oil as a topical anesthetic during inferior alveolar nerve block: A randomized, single-blinded, active-controlled clinical study by Hiba Khalouf, Mawia Karkoutly, MHD Bashier Almonakel

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S-Adenosyl-L-Methionine Augmentation in Patients with Stage II Treatment-Resistant Major Depressive Disorder: An Open Label, Fixed Dose, Single-Blind Study by Domenico De Berardis, Stefano Marini, Nicola Serroni, Gabriella Rapini, Felice Iasevoli, Alessandro Valchera, Maria Signorelli, Eugenio Aguglia, Giampaolo Perna, Anatolia Salone, Giuseppe Di Iorio, Giovanni Martinotti, Massimo Di Giannantonio

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Perioperative Intravenous Patient-Controlled Analgesic Efficacy of Morphine with Combined Nefopam and Parecoxib versus Parecoxib in Gynecologic Surgery: A Randomized, Double-Blind Study by Varinee Lekprasert, Lapuskorn Yapanan, Wichai Ittichaikulthol, Rungrawan Buachai, Phimol Soisod, Areepan Sophonsritsuk

“…This randomized double-blinded control trial recruited participants (n = 72) who underwent gynecologic surgeries and divided them into either a nefopam or control group. …”
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Effects of distant biofield energy healing on adults associated with psychological and mental health-related symptoms: a randomized, placebo-controlled, double-blind study by Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Sambhu Mondal, Snehasis Jana

“…This trial was randomized, placebo-controlled, three parallel-groups, double-blind, and single-center with subjects who have one or more psychological and mental symptoms. …”
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