Virtual reality-based cognitive–behavioural therapy for the treatment of anxiety in patients with acute myocardial infarction: a randomised clinical trial by Jiajun Weng, Junbo Ge, Jiajia Liu, Juying Qian, Xiao Huang, Yuanyuan Li, Juan Peng, Yan'e Lu, Dong Huang, Pingyuan Yang, Shikun Xu, Lihua Guan, Qibing Wang, Zexin Zhao, Yabin Wei

“…Providing timely and easily accessible psychological interventions using virtual reality-based cognitive–behavioural therapy (VR-CBT) could potentially improve both acute and long-term symptoms affecting their mental health.Aims We aim to examine the effectiveness of VR-CBT on anxiety symptoms in patients with AMI who were admitted to the intensive care unit (ICU) during the acute stage of their illness.Methods In this single-blind randomised clinical trial, participants with anxiety symptoms who were admitted to the ICU due to AMI were continuously recruited from December 2022 to February 2023. …”
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Baska Mask versus I-gel in Spontaneously Breathing Anaesthetised Patients: A Randomised Clinical Study by Bhagyavardhan Botta, Yogarajan Ramalingam, Grishma Robba, Tanya Elizabeth, Kala Balasubramanian, Selvamani Subramanian, Senthil Kumar Vannivedu Santhnam, Kavyasri Morampudi

“…Materials and Methods: A prospective randomised single-blinded study was conducted in the Department of Anaesthesiology, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India from October 2019 to October 2020 on 60 American Soceity of Anaesthesiology (ASA) physical status I and II patients, aged between 18-65 years, who were scheduled for minor surgical procedures while spontaneously breathing under general anaesthesia. …”
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Effect of Dendrobium Officinale on Radioactive Oral Mucositis of Nasopharyngeal Carcinoma and Changes of Oral Microecology by Jiaying Yang MM, Yuancai Liu MM, He Yao MM, Mengying Sun MM, Yangbo Tong MM, Guanjun Ma MM, Zhuo Chen MD, Xiang Qian MD, Aiqin Zhang MD

“…Methods: We conducted a randomized double-blinded controlled trial in Zhejiang Cancer Hospital. …”
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Effects of a periodic intermittent theta burst stimulation in Alzheimer’s disease by Yue Wu, Lu Wang, Kai Wang, Shanshan Zhou, Pan Wu, Yibing Yan, Ling Wei, Bensheng Qiu, Yanghua Tian, Zhi Geng, Xingqi Wu, Panpan Hu, Guixian Xiao, Gongjun Ji, Hesheng Liu

“…However, the long-term effects of iTBS on cognitive decline and brain structure in patients with AD are unknown.Aims We aimed to explore whether repeating accelerated iTBS every three months could slow down the cognitive decline in patients with AD.Methods In this randomised, assessor-blinded, controlled trial, iTBS was administered to the left dorsolateral prefrontal cortex (DLPFC) of 42 patients with AD for 14 days every 13 weeks. …”
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Pragmatic algorithm for visual assessment of 4-Repeat tauopathies in [18F]PI-2620 PET Scans by Theresa Bauer, Matthias Brendel, Mirlind Zaganjori, Alexander M. Bernhardt, Alexander Jäck, Sophia Stöcklein, Maximilian Scheifele, Johannes Levin, Thilo van Eimeren, Alexander Drzezga, Osama Sabri, Henryk Barthel, Robert Perneczky, Günter Höglinger, Nicolai Franzmeier, Johannes Gnörich

“…Two readers evaluated scans independently and blinded, with a third reader providing consensus in case of discrepant primary evaluation. …”
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Design of an RCT on cost-effectiveness of group schema therapy versus individual schema therapy for patients with Cluster-C personality disorder: the QUEST-CLC study protocol by Iuno Z. Groot, Anne-Sophie S. M. Venhuizen, Nathan Bachrach, Simone Walhout, Bregje de Moor, Kasper Nikkels, Susanne Dalmeijer, Myrte Maarschalkerweerd, Joël R. van Aalderen, Hinde de Lange, Renske Wichers, Agatha Ph. Hollander, Silvia M. A. A. Evers, Raoul P. P. P. Grasman, Arnoud Arntz

“…Severity of the Cluster-C PD is the primary outcome, assessed with clinical interviews by independent raters blind for treatment. Functioning and wellbeing are important secondary outcomes. …”
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Analysis of the accuracy of disease prediction in pediatric ward patients based on the modified early warning score for children: A randomized controlled trialWhat is already known... by Kang Lin, Xiaojun Weng, Bing Du, Ting Tian, Xiaoxiang Quan

“…Objective: To explore the application effect of modified pediatric early warning score (PEWS) in the early identification of critically ill children in pediatric general wards. Design: A single-blind, two-arm randomized controlled trial was conducted using a convenience sampling method. …”
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Efficacy of Intramuscular versus Intravenous Dexmedetomidine on Attenuation of Haemodynamic Responses to Laryngoscopy and Endotracheal Intubation: A Randomised Clinical Trial by Anupama Kumari, Paras Anand, Jigisha Mehta, Sara Mary Thomas

“…Materials and Methods: This prospective, randomised clinical trial was single-blinded study conducted in the Department of Anaesthesia, Shrimati Bhikhiben Kanjibhai Shah Medical Institute and Research Centre (SBKS MIRC) in Piparia, Vadodara, Gujarat, India over a period of six months from January 2024 to June 2024 on 64 adult patients of American Soceity of Anaesthesiology (ASA) physical status I and II, aged between 18-60 years, posted for surgery under general anaesthesia. …”
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Optimizing oral 3-hydroxybutyrate dosage using pharmacokinetic model to improve cognitive function and mood in healthy subjects by Kentaro Nishioka, Kentaro Nishioka, Kentaro Nishioka, Takahiro Ishimoto, Mariko Sato, Ruki Yasuda, Yumi Nakamura, Hiroshi Watanabe, Toshihide Suzuki, Yudai Araragi, Yukio Kato, Ken-ichi Yoshida, Norihito Murayama

“…In the efficacy study, a randomized, double-blinded, and placebo-controlled crossover trial, the effects of 3-HB at the predicted doses on cognitive function and mood in healthy subjects were assessed by a serial arithmetic test (SAT), the cognitrax, the profile of mood states 2nd edition (POMS2), and fatigue visual analog scale (VAS).ResultsIn the pharmacokinetic study, a one-compartment model that includes saturable and non-saturable absorption pathways, constant biosynthesis, and the linear elimination of 3-HB after oral administration were constructed. …”
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Direct antiglobulin test for the prediction of neonatal hyperbilirubinemia needing an intervention: a systematic review and diagnostic test accuracy meta-analysis by Vijay Kumar Krishnegowda, Viraraghavan Vadakkencherry Ramaswamy, Thangaraj Abiramalatha, Thangaraj Abiramalatha, Tapas Bandyopadhyay, Abdul Kareem Pullattayil S, Prakash Kannan Loganathan, Prakash Kannan Loganathan, Prakash Kannan Loganathan

“…Two reviewers screened the titles and abstracts blinded to each other. A Bayesian bivariate random-effects model was employed for the diagnostic test accuracy meta-analyses. …”
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Acceptability and efficacy of the culturally adapted problem management plus intervention for people with disability in Pakistan: a pilot cluster randomized controlled trial by Basharat Hussain, Basharat Hussain, Muhammad Tahir Khalily, Muhammad Tahir Khalily, Ahmed Waqas, Atif Rahman, Ioannis Angelakis, Anum Nisar, Sabir Zaman, Tanveer Akhtar

“…This research evaluates the adapted PM+’s (IA-PM+) initial efficacy and acceptability in improving mental health among persons living with disabilities, contributing to the integration of mental health services within primary care settings in Pakistan.MethodsThis study employed a two-arm, single-blind cluster randomized controlled trial in a community setting within Union Council Kuri Dolal, Tehsil Gujjar Khan, District Rawalpindi-Pakistan. …”
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MaxEnt-Based Predictions of Suitable Potential Distribution of <i>Leymus secalinus</i> Under Current and Future Climate Change by Shimeng Zhao, Zongxian Zhang, Changyu Gao, Yiding Dong, Zeyao Jing, Lixia Du, Xiangyang Hou

“…The results of this study revealed the suitable climatic conditions and potential distribution range of <i>L. secalinus</i>, which can provide a reference for the conservation, introduction, and cultivation of <i>L. secalinus</i> in new ecological zones, avoiding the blind introduction of inappropriate habitats, and is also crucial for sustaining the economic benefits associated with <i>L. secalinus</i> ecological services.…”
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Upadacitinib in active non-radiographic axial spondyloarthritis: 2-year data from the phase 3 SELECT-AXIS 2 study by Filip Van den Bosch, Atul Deodhar, Denis Poddubnyy, Walter P. Maksymowych, Désirée van der Heijde, Tae-Hwan Kim, Mitsumasa Kishimoto, Xenofon Baraliakos, Xianwei Bu, Ivan Lagunes-Galindo, In-Ho Song, Peter Wung, Koji Kato, Anna Shmagel

“…Patients were randomized 1:1 to receive double-blinded treatment with upadacitinib 15 mg once daily (QD) or placebo for 52 weeks, after which all patients received open-label treatment with upadacitinib 15 mg QD. …”
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Characteristics of adherent and non-adherent patients with hypertension in a Norwegian cross-sectional study by Eirik Olsen, Lene V. Halvorsen, Stine Rognstad, Arleen Aune, Karl Marius Brobak, Ola Undrum Bergland, Vibeke N. Kjær, Knut Liestøl, Marit D. Solbu, Rune Mo, Eva Gerdts, Morten Rostrup, Sverre E. Kjeldsen, Aud Høieggen, Mimi S. Opdal, Anne Cecilie K. Larstorp, Camilla L. Søraas

“…Methods: Patients with hypertension using ≥ 2 antihypertensive agents were invited to participate in this national study performed in a semi-blinded fashion. Exclusion criteria were dementia, substance or alcohol abuse, pregnancy, terminal illnesses, poor Norwegian language skills, or severe kidney failure [glomerular filtration rate (GFR) < 30 mL/min/1.73 m2]. …”
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The Effects of Statin Dose, Lipophilicity, and Combination of Statins plus Ezetimibe on Circulating Oxidized Low-Density Lipoprotein Levels: A Systematic Review and Meta-Analysis o... by Tannaz Jamialahmadi, Fatemeh Baratzadeh, Željko Reiner, Luis E. Simental-Mendía, Suowen Xu, Andrey V. Susekov, Raul D. Santos, Amirhossein Sahebkar

“…PubMed, Scopus, Embase, and Web of Science were searched from inception to February 5, 2021, for randomized controlled trials (RCTs). Two independent and blinded authors evaluated eligibility by screening the titles and abstracts of the studies. …”
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Clinical benefits of modifying the evening light environment in an acute psychiatric unit: A single-centre, two-arm, parallel-group, pragmatic effectiveness randomised controlled t... by Håvard Kallestad, Knut Langsrud, Melanie Rae Simpson, Cecilie Lund Vestergaard, Daniel Vethe, Kaia Kjørstad, Patrick Faaland, Stian Lydersen, Gunnar Morken, Ingvild Ulsaker-Janke, Simen Berg Saksvik, Jan Scott

“…The nature of this study meant it was impossible to blind patients or clinical staff to the lighting condition.…”
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Tools for the Analysis of Quantum Protocols Requiring State Generation Within a Time Window by Bethany Davies, Thomas Beauchamp, Gayane Vardoyan, Stephanie Wehner

“…Specifically, with an example of a blind quantum computing protocol, we illustrate how they may be used to infer <inline-formula><tex-math notation="LaTeX">$w$</tex-math></inline-formula> and <inline-formula><tex-math notation="LaTeX">$p$</tex-math></inline-formula> to optimize the rate of successful protocol execution.…”
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Cardio-renal effect of dapagliflozin and dapagliflozin- saxagliptin combination on CD34 + ve hematopoietic stem cells (HSCs) and podocyte specific markers in type 2 diabetes (T2DM)... by Seshagiri Rao Nandula, Arad Jain, Sabyasachi Sen

“…Methods This is a pilot study evaluating low dose Dapagliflozin 10 mg or low dose Dapa + low dose Saxagliptin combination. 15 subjects were enrolled in 16 weeks, double-blind, three-arm, randomized placebo matched trial, with 10mg Dapa + Saxa placebo (n = 4), 10 mg Dapa + 5 mg Saxa (n = 5) Combo, And Dapa placebo + Saxa placebo (n = 6), Placebo groups. …”
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International education and diplomacy: Education of Serbian students in internship in the 21st century by Vasojević Nena A.

“…It is clear that policymakers in recent years have been striving to solve the "blind spots" related to the project of educating Serbian students abroad, but they are also solving the gaps and deficiencies that are known in the security evidence of security studies. academic community and data collection through sophisticated longitudinal and internationally comparative tools. …”
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Assessment of Birth Preparedness and Complication Readiness among Pregnant Women: A Cross-sectional Study by T Elamathi, K Ananthi, Rimi Singh

“…Materials and Methods: This prospective, double-blinded and randomised clinical study was conducted in the Department of Anaesthesiology, Shrimati Bhikhiben Kanjibhai Shah Medical Institute and Research Centre (a tertiary care institute), Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara, Gujarat, India, from September 2023 to July 2024, with a sample size of 40 patients. …”
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