Comparison of the Fixation Effects of Six Composite Fixatives on Retinal Tissue of Golden Hamsters by WU Haifeng, ZHOU Xiaojiang, LI Chenjiang, LI Huaiyin, GAO Ming

“…The morphological characteristics of retinal tissue cells were observed under a light microscope and scored in a double-blind method to statistically analyze the fixation effect and staining quality of various composite fixative solutions.ResultsRetinal sections fixed with Davidson's fixative exhibited intact morphology without breaks, clear structural layers, well-morphosed nuclei, and tight adhesion between the retina, sclera, and uvea. …”
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Association of Depression/Anxiety Symptoms with Neck Pain: A Systematic Review and Meta-Analysis of Literature in China by Fushui Liu, Ting Fang, Fanyuan Zhou, Meimei Zhao, Mei Chen, Jianyu You, Yuli Jin, Jinmei Xie, Zhongyong Liu

“…Two researchers screened each article and extracted data, respectively, and blinded to the findings of each other. Meta-analysis was conducted by the Cochrane Collaboration’s RevMan 5.3 and Stata 14.0 (Stata Corp LP, USA) software. …”
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Evaluation of Lacrimal Punctal Changes by Anterior Segment Optical Coherence Tomography after Punctal Dilation Versus Punctal Plug Insertion in Cases of Inflammatory Punctual Steno... by Islam Awny, Elshimaa A Mateen Mossa, Tasneem Mohammed Bakheet, Hany Mahmoud, Amr Mounir

“…It is a prospective, interventional, double-blinded controlled randomized study, which was conducted on two groups of patients, the first epiphora group (EG1 25 eyes), who had acquired punctal stenosis and epiphora and managed by simple punctal dilatation. …”
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The Impact of Online Interactive Platform Services on Oral Health Behaviors in Older Adults With Mild Cognitive Impairment: Protocol for a Randomized Controlled Trial by Yin Q, Chai Z, Tao B, Liu P, Luo Y, Zhao Q, Yang B

“…Here we describe the protocol for a study with the following aims: to enhance oral health behaviors through online education tailored to the cognitive load of older adults and to maintain or delay cognitive decline.Patients and Methods: This randomized, parallel, single-blind controlled trial will evaluate the effectiveness of an oral health behavior intervention based on an online interactive platform (e-COM[OH]) in older adults with MCI. …”
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A Randomized Placebo-Controlled N-of-1 Trial: The Effect of Proton Pump Inhibitor in the Management of Gastroesophageal Reflux Disease by Fernando Sierra-Arango, D. M. Castaño, Jennifer D. Forero, Erika D. Pérez-Riveros, Gerardo Ardila Duarte, Maria L. Botero, Andres Cárdenas, Jose De la Hoz-Valle

“…A single-patient trial, placebo-controlled, randomized, double-blind, was carried out from September 25th, 2012, to April 26th, 2013. …”
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Efficacy & safety of brolucizumab 6.0 mg versus 3.6 mg in diabetic macular edema by Sanjay Kumar Mishra, Pradeep Kumar, Amrita Joshi, Aman Saraf, Abhijeet Awasthi, Supriya Dhar, Khaleel M, Atul Kumar, Vipin Rana, Ravi D

“…Method A prospective, pilot randomised controlled, single centre, double blinded, two arm comparative study was conducted between Dec 2022 to Apr 2024. …”
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Deep learning reconstruction of zero-echo time sequences to improve visualization of osseous structures and associated pathologies in MRI of cervical spine by Malwina Kaniewska, Fabio Zecca, Carina Obermüller, Falko Ensle, Eva Deininger-Czermak, Maelene Lohezic, Roman Guggenberger

“…ZTE-DL sequences were reconstructed from raw data using the AirReconDL algorithm. Three blinded readers independently evaluated image quality, artifacts, and bone delineation on a 5-point Likert scale. …”
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Effectiveness of app-based cognitive behavioral therapy for insomnia on preventing major depressive disorder in youth with insomnia and subclinical depression: A randomized clinica... by Si-Jing Chen, Jian-Yu Que, Ngan Yin Chan, Le Shi, Shirley Xin Li, Joey Wing Yan Chan, Weizhen Huang, Chris Xie Chen, Chi Ching Tsang, Yuen Lam Ho, Charles M Morin, Ji-Hui Zhang, Lin Lu, Yun Kwok Wing

“…<h4>Methods and findings</h4>This was a randomized, assessor-blind, parallel group-controlled trial in Chinese youth (aged 15-25 years) with insomnia disorder and subclinical depressive symptoms. …”
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Reduction of pain and functional disability over time in patients treated with zavegepant: a post-hoc analysis of the BHV3500-301 phase 3 randomized controlled trial by Lauren Powell, Fiona O’Sullivan, Pramoda Jayasinghe, Basia Rogula, Feng Dai, Jessica Cirillo, Samantha Sweeney, Lucy Abraham, Jessica Ailani

“…Methods This post-hoc analysis included adult patients with > 1-year history of migraine from BHV3500-301 (NCT04571060): a phase 3 double-blind, randomized, placebo-controlled, single-attack study. …”
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The potential utility of synovial C-reactive protein, interleukin-6, and presepsin in diagnostics of periprosthetic joint infection by Lyudmila V. Lyubimova, Svetlana I. Pavlova, Nikolay S. Nikolaev, Evgeniy A. Lyubimov, Nadezhda N. Pchelova, Vladimir Y. Emelianov

“…A prospective cohort single-center blinded study was conducted involving cases of revision arthroplasty for periprosthetic joint infection (PJI) and aseptic prosthetic loosening. …”
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Impact of dexmedetomidine-ropivacaine versus sufentanil-ropivacaine combination for epidural labour analgesia on neonatal outcomes: a pilot randomised clinical trial by Dong-Xin Wang, Chun-Mei Deng, Ke-Xin Jin, Ting Ding, Yuan Qu

“…Objective To investigate the impact of dexmedetomidine-ropivacaine combination versus sufentanil-ropivacaine combination for epidural labour analgesia on neonatal and maternal outcomes and test the feasibility of a future large, randomised trial.Design A randomised, double-blind, pilot clinical trial from 16 March 2023 to 15 June 2023.Setting A tertiary-care hospital in Beijing, China.Participants 200 women aged≥18 years who had full-term single pregnancy and were scheduled for vaginal delivery with epidural analgesia.Interventions Eligible participants were randomly assigned in a 1:1 ratio to receive self-controlled epidural labour analgesia using ropivacaine supplemented with either dexmedetomidine (0.45 µg/mL for induction and 0.36 µg/mL for maintenance) or sufentanil (0.45 µg/mL for induction and 0.36 µg/mL for maintenance).Main outcomes and measures The primary endpoint was a composite of neonatal morbidity, including 1- or 5 min Apgar score&lt;7, umbilical artery PH&lt;7.1, requirement for immediate assisted ventilation and admission to neonatal ward or intensive care unit within 24 hours. …”
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Changes of Lacrimal Puncta by Anterior Segment Optical Coherence Tomography after Topical Combined Antibiotic and Steroid Treatment in Cases of Inflammatory Punctual Stenosis by Islam Awny, Elshimaa A. Mateen Mossa, Tasneem Mohammed Bakheet, Hany Mahmoud, Amr Mounir

“…Patients and Methods. Double-blinded controlled randomized study which was conducted on two groups of patients who had acquired punctal stenosis and epiphora presented to Ophthalmology Clinics of Sohag University Hospitals in the period between Jan 2021 and April 2021. …”
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Application of the Canon 320 Row Variable Helical Pitch CTA System Combined with Iterative Reconstruction Technology for Lower Limb Vascular Imaging by Wenchao JI, Weili TIAN, Wenya LIU, Lianghao HE, Jian YANG

“…The patients, who all underwent CT angiography of the lower limb arteries, were divided into two groups (A and B; 20 patients/group) through double-blind random grouping. Both groups were treated with 370 mg/mL of the contrast agent iodoparol at a tube voltage of 120 kV. …”
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A novel model-based meta-analysis to indirectly estimate the comparative efficacy of two medications: an example using DPP-4 inhibitors, sitagliptin and linagliptin, in treatment o... by Yan Gong, James Rogers, Christian Friedrich, Sanjay Patel, Alexander Staab, Jorge Luiz Gross, Daniel Polhamus, William Gillespie, Brigitta Ursula Monz, Silke Retlich

“…Comparison of two oral dipeptidyl peptidase (DPP)-4 inhibitors, sitagliptin and linagliptin, for type 2 diabetes mellitus (T2DM) treatment was used as an example.Design Systematic review with MBMA.Data sources MEDLINE, EMBASE, http://www.ClinicalTrials.gov, Cochrane review of DPP-4 inhibitors for T2DM, sitagliptin trials on Food and Drug Administration website to December 2011 and linagliptin data from the manufacturer.Eligibility criteria for selecting studies Double-blind, randomised controlled clinical trials, ≥12 weeks’ duration, that analysed sitagliptin or linagliptin efficacies as changes in glycated haemoglobin (HbA1c) levels, in adults with T2DM and HbA1c &gt;7%, irrespective of background medication.Model development and application A Bayesian model was fitted (Markov Chain Monte Carlo method). …”
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A Study of Combined Onabotulinumtoxin A and Hyaluronic Acid Filler for the Treatment of Enlarged Facial Pores by Vasanop Vachiramon, Sonphet Chirasuthat, Suphagan Boonpethkaew, Nawara Sakpuwadol, Tanat Yongpisarn, Natthachat Jurairattanaporn

“…This study was a prospective, randomized, single-blinded, split-face, controlled trial that enrolled 32 subjects with visibly enlarged pores on both cheeks. …”
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Long-Term Results of Medical and Surgical Methods for Elimination of the Internal Anal Sphincter Spasm in Chronic Anal Fissure (NCT03855046) by S. I. Achkasov, R. Yu. Khryukin, E. E. Zharkov, A. A. Ponomarenko, O. Yu. Fomenko, N. I. Klopkov, Z. Z. Kamaeva, E. Yu. Lebedeva, K. I. Sagidova

“…Patients, researchers and surgeons were not blinded. Patients of the main group underwent fissure excision in combination with relaxation of the internal anal sphincter by botulinum toxin type A (BTA) at a dosage of 40 units, patients of the control group underwent lateral internal sphincterotomy (LIS) with excision of chronic anal fissure. …”
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Clinical Review of Ocular Traumas Resulting in Enucleation or Evisceration in a Tertiary Eye Care Center in Hungary by Gábor Tóth, Milán Tamás Pluzsik, Béla Csákány, Gábor László Sándor, Olga Lukáts, Zoltán Zsolt Nagy, Nóra Szentmáry

“…The main clinical indications for anophthalmic surgery were atrophia/phthisis bulbi (n = 56, 45.2%), acute trauma (n = 25, 20.2%), painful blind eye due to glaucoma (n = 17, 13.7%), endophthalmitis (n = 10, 8.1%), and cosmetic reasons (n = 7, 5.6%). …”
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Adherence and efficacy outcomes in young Australians with suicidal ideation using a self-management app and digital engagement strategy compared with a sham app: a three-arm random... by Michelle Torok, Lauren McGillivray, Daniel Z.Q. Gan, Jin Han, Sarah Hetrick, Quincy J.J. Wong

“…Methods: This was an online double-blind, three-arm parallel randomised controlled trial in Australia. …”
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Factors influencing the effectiveness of SM-VCE method in solving 3D surface deformation by Xupeng Liu, Guangyu Xu, Mingkai Chen, Tengxu Zhang

“…The latter type applies to earthquakes that do not cause surface ruptures and have extensive blind faults. Currently, most research focuses on improving the above types of methods. …”
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At-Home Immersive Virtual Reality Exergames to Reduce Cardiometabolic Risk Among Office Workers: Protocol for a Randomized Controlled Trial by Jing Zhao, Akitomo Yasunaga, Andrew T Kaczynski, Hyuntae Park, Yufeng Luo, Jiuling Li, Ai Shibata, Kaori Ishii, Shohei Yano, Koichiro Oka, Mohammad Javad Koohsari

“…MethodsA 3-arm, single-blinded pilot randomized controlled trial will be conducted to examine the therapeutic effects of at-home immersive VR exergames. …”
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