Virtual reality-based vestibular rehabilitation therapy in patients with acute unilateral vestibulopathy: a randomized controlled trial by Jae Woo Lee, Chul Young Yoon, Chul Young Yoon, Jae Ha Kim, Jae Ha Kim, Young Joon Seo, Young Joon Seo, Young Joon Seo, Tae Hoon Kong, Tae Hoon Kong, Tae Hoon Kong

“…This study aimed to assess the effects of VRT using head-mounted display (HMD) VR technology in patients with acute unilateral vestibulopathy (AUVP) and compare the outcomes with conventional VRT.MethodsWe conducted a single-blinded randomized controlled trial with 60 AUVP patients randomly assigned to VR or control groups. …”
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Effects of intranasal oxytocin on neural reward processing in children and adolescents with reactive attachment disorder: A randomized controlled trial by Shinichiro Takiguchi, Shinichiro Takiguchi, Kai Makita, Takashi X. Fujisawa, Takashi X. Fujisawa, Shota Nishitani, Shota Nishitani, Akemi Tomoda, Akemi Tomoda, Akemi Tomoda

“…Twenty-four male children and adolescents with RAD (10–18 years old) and 27 age- and sex-matched typically developing individuals (10–17 years old) were included in this randomized, double-blind, placebo-controlled, cross-over, functional magnetic resonance imaging study. …”
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Language function improvement and cortical activity alteration using scalp acupuncture coupled with speech-language training in post-stroke aphasia: A randomised controlled study by Bingbing Lin, Jinglei Ni, Xiao Xiong, Lanlan Zhang, Jian Song, Mengxue Wang, Linsong Chai, Yunshi Huang, Jia Huang

“…Methods: This assessor-blinded, parallel-arm design, single-center, randomized clinical trial recruited 64 patients with post-stroke aphasia. …”
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Effect of arm-ergometry versus treadmill supervised exercise on health-related quality of life and mental health in patients with peripheral artery disease: secondary outcomes from... by Sandra Magalhães, Mário Santos, Sofia Viamonte, Fernando Ribeiro, Joana Martins, Cristine Schmidt, Henrique Cyrne-Carvalho

“…Methods This was an ancillary study of the ARMEX trial, a single-center, single-blinded, parallel group, randomized clinical trial, enrolling symptomatic PAD patients referred to a cardiovascular rehabilitation program (CRP). …”
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Clinical efficacy of Tuina therapy combined with traditional Chinese exercises in the treatment of symptomatic lumbar disc herniation: a multicentre randomised controlled trial pro... by Zhihong Fan, Shenghong Jia, Xin Zhou, Chao Li, Jiahao Shao, Xiaofeng Liu, Yitao Liao, Yenan Xu, Dandan He, Shixiang Wu, Xian Zhang

“…Furthermore, clear evidence of clinical efficacy as to whether Tuina combined with TCEs is superior to single TCEs for improving dysfunction and pain in patients with LDH is lacking.Methods/designThe design is a multicentre, assessor-blinded clinical randomised controlled trial. A total of 166 patients with LDH (aged 18–65 years) were recruited from four centres and randomly assigned at a 1:1 ratio to two groups: the TCE group and the Tuina combined with the TCE group. …”
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Weight loss for overweight and obese patients with prostate cancer: a study protocol of a randomised trial comparing clinic-based versus Telehealth delivered EXercise and nutrition... by Robert U Newton, Daniel A Galvão, Dennis R Taaffe, Suzanne K Chambers, David Joseph, Amanda Devine, Colin I Tang, Nigel Spry, Emily Jeffery, Dickon Hayne, Pedro Lopez, P Lyons-Wall, Christine Kudiarasu

“…The purpose of this study was to evaluate the efficacy of telehealth delivered compared with supervised clinic-based delivered exercise and nutrition intervention in overweight/obese patients with prostate cancer.Methods and analysis A single-blinded, two-arm parallel group, non-inferiority randomised trial will be undertaken with 104 overweight/obese men with prostate cancer (body fat percentage ≥25%) randomly allocated in a ratio of 1:1 to a telehealth-delivered, virtually supervised exercise and nutrition programme or a clinic-based, face-to-face supervised exercise and nutrition programme. …”
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Effect of intravenous urokinase vs best medicine treatment on functional outcome for patients with acute minor stroke (TRUST): a randomized controlled trial by Yongli Tao, Yuan Gao, Lu Zhao, Yafang Xu, Chenyang Jiang, Kai Liu, Hui Fang, Lulu Pei, Xin Wang, Rui Zhang, Jun Wu, Jing Yang, Xinsheng Han, Hongling Guo, Baoguo Xue, Jinlou Li, Yuqian Liu, Hongqiu Gu, Kejin Du, Xin Cheng, Qiang Dong, Duolao Wang, Ferdinando S. Buonanno, MingMing Ning, Yuming Xu, Bo Song, the TRUST Trial Investigators

“…Methods This multicenter, open-label, blinded-endpoint, randomized controlled clinical trial enrolled patients with minor stroke within 6 h of symptom onset, with a NIHSS score ≤ 5. …”
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Effect of dry needling, ischemic compression and cross-taping of the masseter in patients with orofacial myofascial pain: a randomized comparative study by B. Macedo de Sousa, N. López-Valverde, N. López-Valverde, A. López-Valverde, A. López-Valverde, D. Neves, M. Santos, J. A. Blanco Rueda, J. A. Blanco Rueda

“…Pain intensity was assessed, randomly, by a single blinded evaluator, according to the Numerical Pain Rating Scale in the pre-treatment period, immediately after, 1–2 weeks and one month later.ResultsImmediately after applying the therapies, there was a greater decrease in pain intensity in dry needling, followed by ischemic compression and a smaller decrease in the cross-taping technique (p < 0.0001; p = 0.0001; p = 0.0014, respectively). …”
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The effectiveness and risks of Treating people with Idiopathic Pulmonary fibrosis with the Addition of Lansoprazole (TIPAL): study protocol for a randomised placebo-controlled mult... by Toby M Maher, A John Simpson, Anthony Cahn, David Thickett, Luke Vale, Allan B Clark, Nazia Chaudhuri, Ian Forrest, Lisa G Spencer, Christopher Ward, Stephen Jones, Ganesh Raghu, Andrew M Wilson, Helen Parfrey, Megan Jones, Matthew Hammond, Jaclyn Ann Smith, Shajahan Wahed

“…We aim to undertake an adequately powered double-blind placebo-controlled randomised multicentre clinical trial to assess the change in forced vital capacity (FVC), cough and other important patient-reported outcomes, following 12-month therapy with PPIs in people with IPF.Methods and analysis A total of 298 patients with IPF diagnosed by a multidisciplinary team according to international guidelines who are not receiving PPIs will be enrolled. …”
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Effect of different intraoperative blood pressure regulation levels on postoperative myocardial injury in patients undergoing radical mastectomy for breast cancer after receiving n... by Ying Zhang, Zhou Zhou, Xinxin Wang, Xiaobao Zhang, Hongya Liu, Xiaoqiao Sang, Yingge Liu

“…MINS is defined as elevated cardiac troponin levels within 30 days after non-cardiac surgery with or without clinical and electrocardiographic signs of cardiac ischaemia.Methods and analysis The study is a single-centre, single-blind, prospective randomised controlled trial. It is expected to enrol 166 subjects receiving neoadjuvant chemotherapy with anthracyclines, between the ages of 40 and 75 years, scheduled for radical mastectomy. …”
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Effect of Nebulisation with Dexmedetomidine versus Magnesium Sulphate on Haemodynamic Response to Laryngoscopy and Intubation and Incidence of Postoperative Sore Throat: A Randomis... by Fateh Pal Singh Gill, Chhaya Suryawanshi

“…Materials and Methods: This randomised clinical, double-blind trial was conducted at Dr. D.Y. Patil Medical College, Pune, Maharashtra, India over the period of two years. …”
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Photobiomodulation preconditioning for oral mucositis prevention and quality of life improvement in chemotherapy patients: a randomized clinical trial by Marwa Khalil, Omar Hamadah, Maher Saifo

“…Materials and methods This is a prospective, randomized, double-blind clinical trial including 45 patients divided into three age- and sex-matched groups. …”
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Posterior Quadratus Lumborum Block versus Transversus Abdominis Plane Block with Bupivacaine and Dexmedetomidine for Postoperative Analgesia following Caesarean Delivery: A Randomi... by V Rajesh Kumar Kodali, Kiran Muthu Rajah, Varun Karuppaiah Thiagarajan

“…Materials and Methods: This study was a prospective, single-blind, randomised clinical trail conducted in the Department of Anaesthesiology at a teritary care teaching Hospital, Chennai, Tamil Nadu from March 2021 to March 2022 on 94 patients (47 in each group) scheduled for elective Lower Segment Caesarean Section (LSCS) and were randomised into two groups: Group T and Group Q. …”
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Comparison of the two treatment methods in primary hyperparathyroidism due to solitary parathyroid adenoma, Ultrasound-guided percutaneous alcohol ablation vs. parathyroidectomy: a... by Mohammad Eslamian, Babak Tavakoli, Alireza Firouzfar, Alireza Pouramini, Bijan Iraj, Mohsen Kolahdouzan, Marjan Mansourian

“…Method A single-centered randomized, not-blinded parallel clinical trial in consecutive patients with pHPT treated with percutaneous alcohol ablation (PEA) between January 2020 and November 2021. …”
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The effect of hyoscine butyl bromide on the active phase of labour among primiparous women delivered at the Jos University Teaching Hospital by George OC, Ajang MF, Anyaka CU

“…Design: This was a hospital-based double-blind placebo-controlled clinical trial Methodology: In this study 120 women were recruited by convenience sampling and randomized into the 3 arms of the study. …”
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Alleviating symptoms of paediatric acute rhinosinusitis and acute otitis media with otorrhea using nasal-spraying Bacillus probiotics: a randomized controlled trial by Thanh Huu Khieu, Dung Phuong Le, Binh Thanh Nguyen, Binh Thanh Ngo, Hong Thi Chu, Duc Minh Truong, Hung Minh Nguyen, Anh Hoa Nguyen, Tung Dinh Pham, Anh Thi Van Nguyen

“…This study evaluated the efficacy of the nasal-spraying probiotics (LiveSpo Navax containing 5 billion Bacillus subtilis and B. clausii spores/5 mL) as a supportive treatment for dual ARS and AOM with otorrhea in a randomized, single-blind, controlled clinical trial. Eighty-two patients (41 per group), aged 1 month to 12 years, received standard care along with nasal spraying of either physiological saline (Control group) or LiveSpo Navax (Navax group), administered three times daily over a 7-day follow-up period. …”
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A single-centre randomised controlled trial comparing the standard method and target-controlled infusion as a method of administering cefoxitin, which is used to prevent surgical s... by Ha-Jung Kim, Kyung Mi Kim, Jong Lyul Lee, In Ja Park, Byung-Moon Choi

“…Methods This prospective, single-centre, parallel-arm, single-blinded, randomised controlled trial with a 1:1 allocation was designed to compare the effectiveness of the TCI method with that of the standard cefoxitin administration method. …”
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Paracetamol did not improve the analgesic efficacy with regional block after video assisted thoracoscopic surgery: a randomized controlled trial by Sujin Kim, Seung Woo Song, Haesung Lee, Chun Sung Byun, Ji-Hyoung Park

“…This monocentric double-blind randomized controlled trial investigates the efficacy of paracetamol after VATS with regional block. …”
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Simulated low-dose dark-field radiography for detection of COVID-19 pneumonia. by Rafael C Schick, Henriette Bast, Manuela Frank, Theresa Urban, Thomas Koehler, Florian T Gassert, Andreas P Sauter, Bernhard Renger, Alexander A Fingerle, Alexandra Karrer, Marcus R Makowski, Daniela Pfeiffer, Franz Pfeiffer

“…Four experienced radiologists served as blinded readers assessing both image modalities, displayed side by side in random order. …”
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Randomized controlled trial of the efficacy of attention and emotional regulation training for children with attention deficit hyperactivity disorder by YANG Letian, HONG Danping, DANG Caiping, ZHU Zhihang, HU Yingzi, PENG Kaiqi, XU Yixuan, LIU Jinlan, YANG Chanjuan, CHENG Daomeng, YU Meng, YIN Weizhen

“…Methods A total of 59 children with ADHD were recruited for group intervention in this randomized controlled double-blind trial. At the beginning and end of the intervention， two interviews were delivered for parents and six sessions of group intervention for children. …”
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