Genotype-phenotype correlations for 17 Chinese families with inherited retinal dystrophies due to homozygous variants by Xue Fan, Zhen Li, Lingzhi Sha, Xunlun Sheng, Weining Rong

“…According to 12 patients (70.6% ), they had the best corrected visual acuity (monocular) < 0.3. 3 were blind, 9 with moderate to severe visual impairment, and 2 with mild visual impairment. 16 homozygous variants were detected in 9 different genes, of which 7 were novel homozygous variants, including frameshift variants, missense variants, and a copy number variant. …”
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Protocol of a parallel group Randomized Control Trial (RCT) for Mobile-assisted Medication Adherence Support (Ma-MAS) intervention among Tuberculosis patients. by Zekariyas Sahile, Lua Perimal-Lewis, Paul Arbon, Anthony John Maeder

“…<h4>Methods</h4>This study is a single-blind parallel-group design individual randomized control trial. …”
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Systematic Review and Network Meta-Analysis of Noninvasive Brain Stimulation on Dysphagia after Stroke by Lingling Li, Hailiang Huang, Yuqi Jia, Ying Yu, Zhiyao Liu, Xin Shi, Fangqi Wang

“…Limited by the number of included studies, more large-sample, multicenter, double-blind, high-quality clinical randomized controlled trials are still needed in the future to further confirm the results of this research.…”
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The effect of absorbable collagen suture for oral implant repair on wound healing and inflammation factors of gingival crevicular fluid by Jingjing Feng, Qiaolong Yu, Xiaoqing Liu

“…Methods: A prospective, randomized, single-blind trial was conducted in patients undergoing dental implant restoration in our hospital. …”
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Contribution of Open Access Databases to Intensive Care Medicine Research: Scoping Review by Julien Kallout, Antoine Lamer, Julien Grosjean, Gaétan Kerdelhué, Guillaume Bouzillé, Thomas Clavier, Benjamin Popoff

“…We included original articles based on 4 open databases of patients admitted to ICUs: Amsterdam University Medical Centers Database, eICU Collaborative Research Database, High time resolution ICU dataset, Medical Information Mart for Intensive Care (II to IV). A double-blinded screening for eligibility was performed, first on the title and abstract and subsequently on the full-text articles. …”
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Effects of a nurse-led peer support intervention for stroke survivors: protocol for a randomised controlled trial by Ying Wu, Janita Pak Chun Chau, Xiaojuan Wan, Limei Xu, Weijuan Gong

“…This study aims to develop a nurse-led peer support intervention for stroke survivors based on the Person–Environment–Occupation–Performance Model and evaluate its effects on the psychosocial outcomes of stroke survivors.Methods and analysis This is an assessor-blinded two-arm randomised controlled trial. A convenience sample of 120 stroke survivors will be recruited from two community centres and one rehabilitation unit in Yangzhou, a medium-sized city in eastern China, with 60 participants each in the intervention and control groups. …”
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Effect of Low-Load Blood Flow Restriction Training After Anterior Cruciate Ligament Reconstruction: A Systematic Review by Baris B. Koc, Alexander Truyens, Marion J.L.F. Heymans, Edwin J.P. Jansen, Martijn G.M. Schotanus

“…Random sequence generation and allocation concealment was defined as high risk in two of the six studies. In all studies blinding of participants and personnel was unclear or could not be performed. …”
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Deep Learning for Discrimination of Early Spinal Tuberculosis from Acute Osteoporotic Vertebral Fracture on CT by Liu W, Wang J, Lei Y, Liu P, Han Z, Wang S, Liu B

“…The performance of the DL models was compared with the diagnostic accuracy of two spine surgeons who performed a blinded review.Results: The MVITV2 model outperformed other architectures in the internal validation set, achieving accuracy of 98.98%, precision of 100%, sensitivity of 97.97%, F1 score of 98.98%, and AUC of 0.997. …”
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Ultra-fast biparametric MRI in prostate cancer assessment: Diagnostic performance and image quality compared to conventional multiparametric MRI by Antonia M. Pausch, Vivien Filleböck, Clara Elsner, Niels J. Rupp, Daniel Eberli, Andreas M. Hötker

“…Two radiologists (R1: 4 years and R2: 3 years of experience) independently assigned PI-RADS scores (PI-RADS v2.1) and assessed image quality (mPI-QUAL score) in two blinded study readouts. Weighted Cohen’s Kappa (κ) was calculated to evaluate inter-reader agreement. …”
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Experiences of Māori and Pacific women recruited into a pregnancy clinical trial in Aotearoa, New Zealand: a Kaupapa Māori qualitative study by Matire Harwood, Benjamin B Albert, Rachel Roskvist, Jamie-Lee Rahiri, Richard Enright, Tania Mullane, Vidit Vinod Satokar

“…In contrast, the major barriers described were time pressures and the distance to the research facility.Conclusions Sixteen Māori and Pacific women who participated in a double-blinded randomised controlled trial shared that successful recruitment of Māori and Pacific women into clinical trials can be promoted by research flexibility participants’ whānau/family responsibilities, effective and culturally safe communication, and research teams striving to build and maintain relationships with participants throughout the trial.Trial registeration number Australian New Zealand Clinical Trials Registry, ACTRN12617001078347p. …”
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Multifocality and Detectability of Prostate Cancer with 3-Tesla Multiparametric Magnetic Resonance Imaging: Correlation with Radical Prostatectomy Mapping Histopathology by Serdar Karadağ, Deniz Noyan Özlü, Ahmet Hacıislamoğlu, Ömer Yıldız, Halil Fırat Baytekin, Mithat Ekşi, Hakan Polat, Alper Bitkin, Ali İhsan Taşçı

“…Suspicious regions of interest (ROIs) were evaluated by a radiologist with 4 years of experience in uroradiology and scored based on Prostate Imaging Reporting and Data System (PIRADS) v2.1. The reader was blinded to the pathological outcomes of any biopsy specimen. …”
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Collagen-1 and elastin expression in cervical tissue: A comparison across cervical elongation, pelvic organ prolapse, and combined conditions by Anis Widyasari, Gatut Hardianto, Etty Hari Kusumastuti, Eighty Mardiyan Kurniawati

“…Two experienced pathologists conducted the analyses in a blinded manner to ensure objective evaluation. Results: Statistical analysis using the Kruskal-Wallis test revealed significant differences in the expression of Collagen-1 across the four groups (CE, POP, CE with POP, and control). …”
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Efficacy of Simple Eye Ointment, Polyethylene Cover, and Eyelid Taping in Prevention of Ocular Surface Disorders in Critically Ill Patients: A Randomized Clinical Trial by Mehdi Ahmadinejad, Esmat Karbasi, Yunes Jahani, Maryam Ahmadipour, Maryam Soltaninejad, Zahra Karzari

“…This study was a double-blind clinical trial (IRCT: 201109225426N3, https://www.irct.ir/trial/5825), in which 152 patients were randomized into three groups and each group underwent a different eye care procedure. …”
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Prevalence of transfusion-transmitted infection and reactive donor response rate in a tertiary care hospital in South India: A retrospective observational study by Kingsley Simon, Kevin Alphones, B. Gayathri Priyadharshini

“…Adding to this, India does not have a centralized donor notification system to notify the donors of their TTI positivity status causing the blood centers to be blind and not having a system to verify the credentials of donors making sure they were not tested positive in other centers in the country. …”
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Cluster of symptoms in kidney failure: A systematic review by Jaime Gomariz-Ruiz, David Pérez-Cruzado, Daniel Gutiérrez-Sánchez

“…Articles were selected independently and blinded by two researchers, and a third researcher was involved in case of disagreement. …”
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IMU Sensor-Based Worker Behavior Recognition and Construction of a Cyber–Physical System Environment by Sehwan Park, Minkyo Youm, Junkyeong Kim

“…However, these systems are limited to areas where CCTV is installed, and in locations like construction sites, numerous blind spots exist due to the limitations of CCTV coverage. …”
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The effect of continuous positive airway pressure (CPAP) application on airway problems in pediatric patients with subglottic stenosis who undergo balloon dilatation by Zeliha Tuncel, Şenay Göksu, Özlem Deligöz, Kemal Tolga Saracoglu, Abdulatif Albasha, Bushra M. Abdallah, Ayten Saracoglu

“…Methods A prospective, double-blinded, parallel-group, randomized controlled study was conducted at Health Sciences University Ümraniye Training and Research Hospital on pediatric patients with subglottic stenosis, aged from 0 to 12 years and who underwent elective balloon dilatation under general anesthesia. …”
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Comparative effects of gong’s mobilization and mobilization with movement in patients with adhesive capsulitis: a randomized clinical trial by Fareeha Amjad, Hasha Asghar

“…The objective of this clinical trial was to compare the effects of Gong’s Mobilization and Mobilization with Movement on pain, range of motion and functional disability in patients with Adhesive Capsulitis. In this triple blinded randomized clinical trial, sixty patients of Adhesive Capsulitis were enrolled within group A (Gong’s Mobilization) and group B (Mobilization with Movement). …”
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Shatavari supplementation during eight weeks of resistance training increases training load, enhances skeletal muscle contractility and alters the skeletal muscle proteome in older... by Elsa Greed, Elsa Greed, Jack Pritchard, Lauren Struszczak, Esra Bozbaş, Georgia Ek, Jordan Acheson, Jordan Acheson, Ben Winney, Aaliyah Qadir, Karl Ka-Lam Wong, Joanna Bowtell, Mary O’Leary

“…However, mechanistic insights are limited and the effects of shatavari on muscle function require further characterization.MethodsIn this randomized, double-blind trial, 17 young (23 ± 5 yr) and 22 older (63 ± 5 yr) women completed an 8-week leg resistance training programme. …”
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Efficacy and safety of the Russian protease inhibitor narlaprevir at treatment-naive and earlier treated noncirrhotic patients with the 1st genotype chronic hepatitis C (PIONEER st... by M. V. Mayevskaya, V. T. Ivashkin, O. O. Znoyko, Ye. A. Klimova, D. T. Abdurakhmanov, I. G. Bakulin, P. O. Bogomolov, E. Z. Burnevich, M. Yu. Galushko, N. I. Geyvandova, K. V. Zhdanov, Ye. V. Esaulenko, S. N. Kizhlo, D. Yu. Konstantinov, N. I. Mironova, V. G. Morozov, Ye. A. Strebkova, I. G. Nikitin, M. F. Osipenko, V. D. Pasechnikov, O. I. Sagalova, I. M. Khayertynova, V. P. Chulanov, A. A. Yakovlev, I. A. Vasyutin, Ye. P. Tarkhova, E. N. Krasavina, M. Yu. Samsonov

“…To estimate efficacy and safety of narlaprevir (NVR) with ritonavir (RTV), pegilated interferon (peg-IFN) and ribavirin (RBV) at treatmentnaïve and earlier treated noncirrhotic patients with chronic hepatitis C caused by the 1st virus genotype in double blind placebo-controlled 3rd phase study (PIONEER). …”
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