Olfactory Bulb Field Potentials and Respiration in Sleep-Wake States of Mice by Jakob Jessberger, Weiwei Zhong, Jurij Brankačk, Andreas Draguhn

“…In order to validate such measurements in freely behaving mice, we compared rhythmic LFP in the OB with two respiration-related biophysical parameters: whole-body plethysmography (PG) and nasal temperature (thermocouple; TC). …”
Get full text

Recursive seed amplification detects distinct α-synuclein strains in cerebrospinal fluid of patients with Parkinson’s disease by Stefan Bräuer, Iñaki Schniewind, Elisabeth Dinter, Björn H. Falkenburger

“…We found that fibrils, amplified from CSF by recursive SAA, exhibit two types of distinct biophysical properties and have different seeding capacities in cells. …”
Get full text

Exploring the Gating Mechanism of the Human Copper Transporter, hCtr1, Using EPR Spectroscopy by Shahaf Peleg, Shelly Meron, Yulia Shenberger, Lukas Hofmann, Lada Gevorkyan-Airapetov, Sharon Ruthstein

“…The role of the extracellular N-terminal domains is particularly unclear due to the absence of a high-resolution structure of the full-length hCtr1 protein and limited biochemical and biophysical characterization of the transporter in solution and in cell. …”
Get full text

Role of the Psi Packaging Signal and Dimerization Initiation Sequence in the Organization of Rous Sarcoma Virus Gag-gRNA Co-Condensates by Gregory S. Lambert, Rebecca J. Kaddis Maldonado, Leslie J. Parent

“…Recent studies have demonstrated that the Gag proteins of Rous sarcoma virus (RSV) and human immunodeficiency virus type-1 (HIV-1) undergo nuclear trafficking, colocalize with nascent genomic viral RNA (gRNA) at transcription sites, may interact with host transcription factors, and display biophysical properties characteristic of biomolecular condensates. …”
Get full text

Effective Combination of Advancing Transplantation Date with High-Yielding Cultivars for Paddy Rice Could Increase the Yield Potential Under Climate Warming in China by He Zhang, Guangsheng Zhou, Qijin He

“…Based on field observation data from 2000 to 2012 and a biophysical process-oriented CERES-Rice crop model at three typical sites, we investigated the effects of cultivar improvement, different transplanting dates and their interactions on rice yield potential in the major paddy rice production areas of China. …”
Get full text

CLN-978, a novel half-life extended CD19/CD3/HSA-specific T cell-engaging antibody construct with potent activity against B-cell malignancies with low CD19 expression by Agapitos Patakas, Bochong Li, Naveen K Mehta, Kristan Meetze, Patrick A Baeuerle, Jennifer S Michaelson, Hannah M Findlay, Timothy B London

“…In this setting, we biophysically characterize and report the activities of CLN-978 in cell co-culture assays, multiple mouse models and non-human primates.Results Human T cells redirected by CLN-978 could eliminate target cells expressing less than 300 copies of CD19 on their surface. …”
Get full text

Investigating time-independent and time-dependent diffusion phenomena using steady-state diffusion MRI by Benjamin C. Tendler

“…I subsequently introduce an approach to incorporate existing biophysical models into DW-SSFP without the requirement of extensive derivations, with time dependence estimated via a Gaussian phase approximation representation of the DW-SSFP signal. …”
Get full text

ApoB100 remodeling and stiffened cholesteryl ester core raise LDL aggregation in familial hypercholesterolemia patients by Maria Teresa La Chica Lhoëst, Andrea Martínez, Eduardo Garcia, Jany Dandurand, Anna Polishchuk, Aleyda Benitez-Amaro, Ana Cenarro, Fernando Civeira, Amable Bernabé, David Vilades, Joan Carles Escolà-Gil, Valerie Samouillan, Vicenta Llorente-Cortes

“…This study examined LDL aggregation and its relationship with LDL lipid composition and biophysical properties in patients with FH compared to controls. …”
Get full text

Exploring safety at mass gathering events through the lens of three different stakeholders by Alison Hutton, Martin Robertson, Jamie Ranse

“…This paper comes at a time when there is an acute need for appropriate application of psychosocial understanding and biophysical knowledge for the safe management of the social environment of MGE, and the broader community. …”
Get full text

Autologous Fat Grafting in the Treatment of Facial Scleroderma by Mehdi Gheisari, Arman Ahmadzadeh, Nilofar Nobari, Behzad Iranmanesh, Nikoo Mozafari

“…Evaluations included mouth opening capacity, mouth handicap in systemic sclerosis (MHISS), Rodnan skin sclerosis score, skin biophysical properties using a sensitive biometrologic device with the assessment of cutaneous resonance running time (CRRT), volumizing and aesthetic effects based on pre- and posttreatment photographs, possible side effects, and global patient satisfaction. …”
Get full text

LAND SUITABILITY ANALAYSIS OF SESAME CROP USING GIS TECHNIQUES by Ramesh Kumar Ghimire, Anuj Dhakal, Amir Pandit, Pragyan Ghimire, Sagar Pokharel

“…The research utilized a comprehensive methodology, blending Pair- wise Comparison Matrix (PWCM) and Weighted Multi-Criteria Analysis with diverse biophysical criteria through Analytical Hierarchy Process (AHP). …”
Get full text

Symmetry and stability of orientationally ordered collective motions of self-propelled, semiflexible filaments by Madhuvanthi Guruprasad Athani, Daniel A. Beller

“…Active phases are especially rich when the active units are sufficiently anisotropic to produce liquid crystalline order and thus active nematic phenomena, with important biophysical examples provided by cytoskeletal filaments including microtubules and actin. …”
Get full text

The effects of contour-based rainwater harvesting and integrated nutrient management on maize yields in semi-arid regions of Zimbabwe by Pasipanodya Chiturike, Jephta Gotosa, Innocent Wadzanai Nyakudya, Sandra M. Madamombe, Ronald Mandumbu, Ngonidzashe Chirinda, Andrew Tapiwa Kugedera, George Nyamadzawo

“…The negative effects of these biophysical factors have been worsened by climate change. …”
Get full text

Structural and Functional Characterization of Recombinant Interleukin-10 from Indian Major Carp Labeo rohita by Sweta Karan, Pujarini Dash, Himani Kaushik, Pramoda K. Sahoo, Lalit C. Garg, Aparna Dixit

“…In the present study, we report large scale production and purification of biologically active recombinant IL-10 of L. rohita (rLrIL-10) using a heterologous expression system and its biophysical and functional characterization. High yield (~70 mg/L) of soluble rLrIL-10 was obtained at shake flask level. …”
Get full text

Mass‐Guided Single‐Cell MALDI Imaging of Low‐Mass Metabolites Reveals Cellular Activation Markers by James L. Cairns, Johanna Huber, Andrea Lewen, Jessica Jung, Stefan J. Maurer, Tobias Bausbacher, Stefan Schmidt, Pavel A. Levkin, Daniel Sevin, Kerstin Göpfrich, Philipp Koch, Oliver Kann, Carsten Hopf

Get full text

The Kinetics of Joined Action of Triplet-Triplet Annihilation and First-Order Decay of Molecules in T1 State in the Case of Nondominant First-Order Process: The Kinetic Model in th... by Paweł Borowicz, Bernhard Nickel

Get full text

Erratum to “Vitamin D Promotes MSC Osteogenic Differentiation Stimulating Cell Adhesion and αVβ3 Expression” by Francesca Posa, Adriana Di Benedetto, Elisabetta A. Cavalcanti-Adam, Graziana Colaianni, Chiara Porro, Teresa Trotta, Giacomina Brunetti, Lorenzo Lo Muzio, Maria Grano, Giorgio Mori

Get full text

Pathogenetic aspects and modern possibilities of therapy of vulvovaginal candidiasis by Margarita R. Rakhmatulina, Elena V. Lipova, Viktoria A. Nyanenko

Get full text

Physiochemical and functional evaluation of the first-in-class anti-cancer IgE antibody drug, MOv18, through process development and good manufacturing practice production by Heather J Bax, Jitesh Chauhan, Alexandra J McCraw, Melanie Grandits, Chara Stavraka, Heike Lentfer, Tim Hillyer, Simon Carroll, Kim Vigor, Chris Selkirk, Mariangela Figini, Jack Cheeseman, Paulina A Urbanowicz, Richard A Gardner, Daniel I R Spencer, Nigel Westwood, Sarah Mellor, James Spicer, Debra H Josephs, Sophia N Karagiannis

“…During the process development and scaled Good Manufacturing Practice production, we demonstrate the retention of glycosylation state, biophysical profile, and functional characteristics of MOv18 IgE, including Fc-mediated mast cell degranulation and tumor cell killing. …”
Get full text

LAND SUITABILITY ASSESSMENT FOR SOYBEAN (GLYCINE MAX) IN BARDAGHAT MUNICIPALITY USING GIS TECHNIQUES by Birendra Tiwar, Amrit Dumre, Mahesh Jaishi

“…The research employed a comprehensive methodology, combining Pair-wise Comparison Matrix (PWCM) and Weighted Multi-Criteria Analysis via Analytical Hierarchy Process (AHP) to consider various biophysical criteria. Thematic maps were generated using Remote Sensing, Geostatistics, and Geographic Information Systems (GIS). …”
Get full text