Development, validation, and usage of metrics to evaluate the quality of clinical research hypotheses by Xia Jing, Yuchun Zhou, James J. Cimino, Jay H. Shubrook, Vimla L. Patel, Sonsoles De Lacalle, Aneesa Weaver, Chang Liu

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The algebraic extended atom-type graph-based model for precise ligand–receptor binding affinity prediction by Farjana Tasnim Mukta, Md Masud Rana, Avery Meyer, Sally Ellingson, Duc D. Nguyen

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Digital twins as global learning health and disease models for preventive and personalized medicine by Xinxiu Li, Joseph Loscalzo, A. K. M. Firoj Mahmud, Dina Mansour Aly, Andrey Rzhetsky, Marinka Zitnik, Mikael Benson

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Mitotic block and epigenetic repression underlie neurodevelopmental defects and neurobehavioral deficits in congenital heart disease by George C. Gabriel, Hisato Yagi, Tuantuan Tan, Abha Bais, Benjamin J. Glennon, Margaret C. Stapleton, Lihua Huang, William T. Reynolds, Marla G. Shaffer, Madhavi Ganapathiraju, Dennis Simon, Ashok Panigrahy, Yijen L. Wu, Cecilia W. Lo

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The Limited Impact of Running Performance on Football Success in the Turkish Super League by Spyridon Plakias, Sotiris Tasoulis, Angelos E. Kyranoudis, Christos Kokkotis, Serafeim Moustakidis

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Mapping dynamic regulation of gene expression using single-cell transcriptomics and application to complex disease genetics by Hanna Abe, Phillip Lin, Dan Zhou, Douglas M. Ruderfer, Eric R. Gamazon

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Myofibroblasts emerge during alveolar regeneration following influenza-virus-induced lung injury by Ali Khadim, Georgios Kiliaris, Ana Ivonne Vazquez-Armendariz, Tara Procida-Kowalski, David Glaser, Marek Bartkuhn, Tanya Malik, Xuran Chu, Alena Moiseenko, Irina Kuznetsova, Negah Ahmadvand, Arun Lingampally, Stefan Hadzic, Ioannis Alexopoulos, Yuexin Chen, Andreas Günther, Jürgen Behr, Jens Neumann, Herbert B. Schiller, Xiaokun Li, Norbert Weissmann, Thomas Braun, Werner Seeger, Malgorzata Wygrecka, Rory E. Morty, Susanne Herold, Elie El Agha

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Impact of leadership behaviour on physician well-being, burnout, professional fulfilment and intent to leave: a multicentre cross-sectional survey study by Mihriye Mete, Charlotte Goldman, Tait Shanafelt, Daniel Marchalik

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Lower electronic health record adoption and interoperability in rural versus urban physician participants: a cross-sectional analysis from the CMS quality payment program by A. Jerrod Anzalone, Carol R. Geary, Ran Dai, Shinobu Watanabe-Galloway, James C. McClay, James R. Campbell

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A scalable tool for analyzing genomic variants of humans using knowledge graphs and graph machine learning by Shivika Prasanna, Ajay Kumar, Deepthi Rao, Eduardo J. Simoes, Praveen Rao

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Association of whole grain food consumption with lung cancer risk: a prospective cohort study by Kanran Wang, Junhan Zhao, Dingyi Yang, Mao Sun, Yongzhong Wu, Wei Zhou

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From physical activity patterns to cognitive status: development and validation of novel digital biomarkers for cognitive assessment in older adults by Ling-Jie Fan, Feng-Yi Wang, Jun-Han Zhao, Jun-Jie Zhang, Yang-An Li, Jia Tang, Tao Lin, Quan Wei

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Effect of porcine collagen matrix versus rotated pedicle palatal connective tissue flap on the soft-tissue closure after the immediate posterior implantation: study protocol for a... by Wei Zhang, Si Chen, Chenyang Zhang, Shuobo Fang, Zhengjie Dong, Tong Chen, Wanqi Lv, Keyi Hao

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Can Radiomics of Dynamic PET Imaging with 11C-methionine Predict EGFR Amplification Status in Glioblastoma? by Gleb DANILOV, Andrey POSTNOV, Diana KALAEVA, Nina VIKHROVA, Tatyana KOBYAKOVA

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An ontology-based rare disease common data model harmonising international registries, FHIR, and Phenopackets by Adam S. L. Graefe, Miriam R. Hübner, Filip Rehburg, Steffen Sander, Sophie A. I. Klopfenstein, Samer Alkarkoukly, Ana Grönke, Annic Weyersberg, Daniel Danis, Jana Zschüntzsch, Elisabeth F. Nyoungui, Susanna Wiegand, Peter Kühnen, Peter N. Robinson, Oya Beyan, Sylvia Thun

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S‐PLM: Structure‐Aware Protein Language Model via Contrastive Learning Between Sequence and Structure by Duolin Wang, Mahdi Pourmirzaei, Usman L. Abbas, Shuai Zeng, Negin Manshour, Farzaneh Esmaili, Biplab Poudel, Yuexu Jiang, Qing Shao, Jin Chen, Dong Xu

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Prediction of delirium occurrence using machine learning in acute stroke patients in intensive care unit by Hyungjun Kim, Hyungjun Kim, Min Kim, Da Young Kim, Dong Gi Seo, Ji Man Hong, Ji Man Hong, Dukyong Yoon, Dukyong Yoon

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Association of Intensive Endoscopic Burden with Esophageal Cancer Detection: A Nationwide Cohort Study by Yeunji Lee, Eunyoung Lee, Bumhee Park, Gil Ho Lee, Sun Gyo Lim, Sung Jae Shin, Choong-Kyun Noh, Kee Myung Lee

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SGCL-LncLoc: An Interpretable Deep Learning Model for Improving lncRNA Subcellular Localization Prediction with Supervised Graph Contrastive Learning by Min Li, Baoying Zhao, Yiming Li, Pingjian Ding, Rui Yin, Shichao Kan, Min Zeng

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“I think we're on a cusp of some change:” coping and support for mental wellness among Black American women by Terika McCall, Terika McCall, Terika McCall, Meagan Foster, Holly Tomlin, Holly Tomlin, Bolatito Adepoju, Mckenzie Bolton-Johnson, Chyrell D. Bellamy

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