Modification of the telomerase gene with human regulatory sequences resets mouse telomeres to human length by Fan Zhang, De Cheng, Kenneth I. Porter, Emily A. Heck, Shuwen Wang, Hui Zhang, Christopher J. Davis, Gavin P. Robertson, Jiyue Zhu

“…Abstract Telomeres shorten with each cell division, serving as biomarkers of aging, with human tissues exhibiting short telomeres and restricted telomerase expression. …”
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Long-Term Effect of Mediterranean-Style Diet and Calorie Restriction on Biomarkers of Longevity and Oxidative Stress in Overweight Men by Katherine Esposito, Carmen Di Palo, Maria Ida Maiorino, Michela Petrizzo, Giuseppe Bellastella, Isabella Siniscalchi, Dario Giugliano

“…We report the effects of a Mediterranean-style diet, with or without calorie restriction, on biomarkers of aging and oxidative stress in overweight men. 192 men were randomly assigned to either a Mediterranean-style diet or a conventional diet. …”
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Achieving healthy aging through gut microbiota-directed dietary intervention: Focusing on microbial biomarkers and host mechanisms by Yue Xiao, Yingxuan Feng, Jianxin Zhao, Wei Chen, Wenwei Lu

“…Aim of Review: This review aims to summarize the characteristics of the gut microbiota associated with aging, explore potential biomarkers of aging and address microbiota-associated mechanisms of host aging focusing on intestinal barrier and immune status. …”
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Serum Growth Differentiation Factor 15 is Negatively Associated with Leukocyte Telomere Length by Jie Yu, Yiwen Liu, Huabing Zhang, Fan Ping, Wei Li, Lingling Xu, Yuxiu Li

“…Background: Telomere length(TL)and mitochondrial DNA copy number(mtDNAcn) are classic biomarker of aging. Recently, growth differentiation factor 15(GDF15) has attracted considerable attention as a vital component in the aging process. …”
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Development and Validation of a Predictive Model Based on Serum Silent Information Regulator 6 Levels in Chinese Older Adult Patients: Cross-Sectional Descriptive Study by Yuzi You, Wei Liang, Yajie Zhao

“… Abstract BackgroundSerum levels of silent information regulator 6 (SIRT6), a key biomarker of aging, were identified as a predictor of coronary artery disease (CAD), but whether SIRT6 can distinguish severity of coronary artery lesions in older adult patients is unknown. …”
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Gut Dysbiosis and Muscle Aging: Searching for Novel Targets against Sarcopenia by Anna Picca, Francesca Fanelli, Riccardo Calvani, Giuseppina Mulè, Vito Pesce, Alex Sisto, Cecilia Pantanelli, Roberto Bernabei, Francesco Landi, Emanuele Marzetti

“…Although muscle aging has been increasingly recognized as a biomarker of aging, the pathophysiology of sarcopenia is to date only partially appreciated. …”
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Age-Related Changes in Gut Health and Behavioral Biomarkers in a Beagle Dog Population by Anna Fernández-Pinteño, Rachel Pilla, Jan Suchodolski, Emmanuelle Apper, Celina Torre, Anna Salas-Mani, Xavier Manteca

“…However, further research is needed to better understand the mechanisms and specific pathways involved in the relationship between the studied biomarkers and age.…”
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Shorter telomere length in COPD cases secondary to biomass-burning smoke exposure by Angélica Domínguez-de-Barros, Gloria Pérez-Rubio, Ingrid Fricke-Galindo, Alejandra Ramírez-Venegas, Malena Gajate-Arenas, Rafael Hernández-Zenteno, Salvador García-Carmona, Robinson Robles-Hernández, María E. Ramírez-Díaz, Filiberto Cruz-Vicente, María L. Martínez-Gómez, Jacob Lorenzo-Morales, Ramcés Falfán-Valencia, Elizabeth Córdoba-Lanús

“…COPD has been described as an accelerated aging disease, and telomere length is a biomarker of aging. Methods This study examined telomere length in 189 Mexican individuals, from which 93 developed COPD secondary to BS exposure (BE-COPD); the rest of the participants were exposed to BS but did not develop the disease. …”
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Association of Albumin‐To‐Creatinine Ratio With Diabetic Retinopathy Among US Adults (NHANES 2009–2016) by Han Dai, Ling Liu, Weiwei Xu

“…Comprehensive evaluation of renal function and glycaemic control biomarkers, considering age‐ and comorbidity‐specific patterns, could improve DR risk prediction and management. …”
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