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17721
Application of Biochar-Immobilized <i>Bacillus megaterium</i> for Enhancing Phosphorus Uptake and Growth in Rice
Published 2025-01-01“…Additionally, carbon utilization analysis was applied using the commercial Biolog system, revealing that the MOF treatment significantly increased the utilization of carbohydrates, polymers, and amino acid carbon sources. …”
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17722
Development of a TCR-like antibody and chimeric antigen receptor against NY-ESO-1/HLA-A2 for cancer immunotherapy
Published 2022-03-01“…The specificity and affinity of those antibodies were characterized by flow cytometry, ELISA, biolayer interferometry, and confocal imaging. The biological functions of CAR-T cells were evaluated against target tumor cells in vitro. …”
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17723
Rare variants in previously identified linkage regions associated with carotid plaque in Dominican Republic families.
Published 2022-01-01“…Notably, SCUBE2 encodes a protein which interacts with vascular endothelial growth factor (VEGF) receptor 2 to regulate VEGF-induced angiogenesis, thus providing biologic plausibility for this gene in atherosclerosis. …”
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17724
Ellagic Acid Alleviates Rheumatoid Arthritis in Rats through Inhibiting MTA1/HDAC1-Mediated Nur77 Deacetylation
Published 2021-01-01“…Rescue experiments demonstrated that Nur77 knockdown reversed the effects of EA on MH7A cell biological behaviors. Additionally, EA treatment attenuated arthritis index, paw swelling, synovial hyperplasia, and inflammation in collagen-induced arthritis (CIA) rats. …”
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17725
Integrated analysis of the transcriptome and hormone metabolome elucidates the regulatory mechanisms governing walnut bud germination
Published 2025-01-01“…Our results emphasized four key biological processes—cellular response to ethylene stimulus, phenylpropanoid metabolic process, ethylene-activated signaling pathway, and monooxygenase activity—along with several relevant pathways, including plant hormone signal transduction, flavone and flavonol biosynthesis, biosynthesis of secondary metabolites, and MAPK signaling pathway, all crucial for walnut bud germination. …”
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17726
Artificial intelligence-enabled discovery of a RIPK3 inhibitor with neuroprotective effects in an acute glaucoma mouse model
Published 2025-01-01“…Subsequently, these target candidates were validated using molecular simulations (molecular docking, absorption, distribution, metabolism, excretion, and toxicity [ADMET] prediction, and molecular dynamics simulations) and biological experiments (Western blotting and fluorescence staining) in vitro and in vivo. …”
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17727
Clinical and genetic drivers of oligo-metastatic disease in colon cancer
Published 2025-02-01“…This study aims to identify clinical and biological factors uniquely associated with oligo-metastatic behavior. …”
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17728
mRNA-lncRNA gene expression signature in HPV-associated neoplasia and cervical cancer
Published 2024-05-01“…Changes in gene activity in tumors reflect the biological diversity of cellular phenotype and physiological functions and can be an important diagnostic marker. …”
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17729
THE GENE POOL FOR TABLE BEET BREEDING (MODERN ASPECTS OF STUDY AND USE)
Published 2019-10-01“…The research has resulted in the identification of table beet accessions characterized by a complex of biological and economically important traits. The relationships between earliness, resistance to bolting and cold tolerance have been revealed. …”
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17730
Terminalia catappa Extract Palliates Redox Imbalance and Inflammation in Diabetic Rats by Upregulating Nrf-2 Gene
Published 2021-01-01“…Molecular docking and prediction of major TCA phytoconstituents’ biological activity related to T2DM-induced oxidative stress were evaluated in silico. …”
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17731
Protein quality of four indigenous edible insect species in Nigeria
Published 2018-06-01“…Cricket was found to have the highest amino acid score (0.91), protein efficiency ratio (1.78), net protein ratio (3.04) biological value (93.02%) and protein digestibility corrected for amino acid score (0.73) as compared to other insect proteins analysed. …”
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17732
Modern trends in breeding and genetic improvement of sunflower varieties and hybrids at VNIIMK
Published 2021-07-01“…Pustovoit All-Russian Research Institute of Oil Crops (VNIIMK) in all areas in demand on the market and is based on fundamental biological research. In the field of breeding for faster maturing, the following commercial cultivars were obtained: very early maturing, cv. …”
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17733
Anti-TROVE2 Antibody Determined by Immune-Related Array May Serve as a Predictive Marker for Adalimumab Immunogenicity and Effectiveness in RA
Published 2021-01-01“…Anti-drug antibody (ADAb) development is associated with secondary therapeutic failure in biologic-treated rheumatoid arthritis (RA) patients. …”
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17734
Quarantine nematode species and pathotypes potentially dangerous for domestic potato production: populations diversity and the genetics of potato resistance
Published 2020-12-01“…The main components of successful protection preventing a wide distribution of parasitic nematodes are quarantine measures, agricultural techniques, biological methods of protection and cultivation of resistant cultivars. …”
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17735
Undernutrition risk and obesity increase the risk of osteosarcopenia in Mexican adults aged 50 and over: a prospective cohort study
Published 2025-01-01“…On the other hand, obesity has been associated with osteosarcopenia, and several biological mechanisms in the relationship between muscle, bone, and fat have been identified. …”
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17736
Insights into the Mode of Action of Novel Morpholinated Curcumin Derivatives Exhibiting Potent Antitumor Activity in Bladder Cancer Cells In Vitro
Published 2025-01-01“…Although curcumin is a well-known natural polyphenol with many biological activities, its clinical application has been limited by low aqueous solubility and stability. …”
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17737
HISTOLOGICAL ANALYSIS OF LYMPHOID MASSES OF THE STOMACH AND SMALL INTESTINE IN THE CLINICAL AND PATHOGENETIC PROFILE OF BABESIOSIS
Published 2021-08-01“…Verification was carried out by cytological, ultramicroscopic, molecular genetic methods (polymerase chain reaction) and in a biological experiment on animals. Analysis of specimens of the lamina propria in the gastric mucosa of the animals in the experimental group and clinical observation group established that the latter contained diffuse accumulations of the lymphoid tissue. …”
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17738
Inorganic polyphosphate and the stringent response coordinately control cell division and cell morphology in Escherichia coli
Published 2025-02-01“…These results provide new insights into the relationship between polyP synthesis and the stringent response in bacteria and point toward their having a joint role in controlling metabolism, cell division, and cell growth.IMPORTANCECell division is a fundamental biological process, and the mechanisms that control it in Escherichia coli have been the subject of intense research scrutiny for many decades. …”
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17739
Determining the status of small dense low-density lipoprotein cholesterol level in women undergoing menopausal transition
Published 2025-01-01“…Our aim is to evaluate the relationship between serum sdLDL-C level and different menopausal status in a Chinese women population.MethodsIn 2022, a cross-sectional study was conducted including electronic standardized questionnaire surveys, anthropometric measurements, and biological specimen examinations based on communities. …”
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17740
NEIL3 Mediates Lung Cancer Progression and Modulates PI3K/AKT/mTOR Signaling: A Potential Therapeutic Target
Published 2022-01-01“…Quantitative real-time PCR (qRT-PCR) and western blot analyses were utilized to detect RNA and protein levels. Biological differences between groups were determined by gene set enrichment analysis (GSEA). …”
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