Effect of Zbtb33 gene knockout and bacterial lipopolysaccharide on home cage behavior in mice by N. V. Khotskin, I. E. Sorokin, E. A. Kulikova, A. V.  Kulikov

“…The results shed light on the biological significance of the Kaiso gene and serve as a justification for the necessity of the normal functioning of this gene in natural populations.…”
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Association of bud and anther morphology with developmental stages of the male gametophyte of melon (Cucumis melo L.) by M. L. Nguyen, T.N.B.T. Huyen, D. M. Trinh, A. V. Voronina

“…To successfully apply this technique in a new culture, one has to optimize many of its elements: f irst, f ind the biological markers for selecting the f lower buds containing the microspores of certain development stages. …”
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Identification of a distinctive immunogenomic gene signature in stage-matched colorectal cancer by Pankaj Ahluwalia, Ashis K. Mondal, Ashutosh Vashisht, Harmanpreet Singh, Ahmet Alptekin, Kalyani Ballur, Nivin Omar, Meenakshi Ahluwalia, Kimya Jones, Amanda Barrett, Vamsi Kota, Ravindra Kolhe

“…Orthogonal analyses included single-cell profiling, differential gene expression, immune cell deconvolution, neoantigen prediction, and biological pathway assessment. Results A 3-gene signature (GTF3A, PKM, and VEGFA) was found to be associated with overall survival in the AU cohort (HR = 2.26, 95% CI 1.05–4.84, p = 0.02, 93 patients), TCGA cohort (HR = 1.57, 95% CI 1.05–2.35, p < 0.02, 435 patients) and four other GEO datasets. …”
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Temperature Is a Key Factor Affecting Total Phosphorus and Total Nitrogen Concentrations in Northeastern Lakes Based on Sentinel-2 Images and Machine Learning Methods by Haoming Qin, Chong Fang, Ge Liu, Kaishan Song, Zhuoshi Li, Sijia Li, Hui Tao, Zhaojiang Yan

“…A positive correlation between temperature and TP concentration was observed, as higher temperatures enhance biological activity. In contrast, a negative correlation was found with TN concentration, as higher temperatures promote phytoplankton growth and reproduction. …”
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FLT3 is associated with dendritic cell infiltration, tertiary lymphoid structure construction, and predict response to checkpoint inhibitors immunotherapy in solid cancers by Yongchang Tang, Hong Wang, Jiankun Zhang, Chunhui Yang, Fei Xu, Yan Song, Tianen Li, Qiangbo Zhang

“…Additionally, we explored genes co-expressed with FLT3 and performed gene ontology analysis to identify associated biological processes. We also examined the relationship between FLT3 expression and markers of various immune cells, tertiary lymphoid structures (TLSs), and epithelial-mesenchymal transition. …”
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CD4 CAR-T cells targeting CD19 play a key role in exacerbating cytokine release syndrome, while maintaining long-term responses by Alice Bergamini, Barbara Camisa, Attilio Bondanza, Fabio Ciceri, Chiara Bonini, Monica Casucci, Beatrice Greco, Camilla Bove, Silvia Arcangeli, Laura Falcone, Rita El Khoury, Anna De Lucia

“…Interestingly, the combination of CD4.BBz with CD8.28z CAR-T cells resulted in the lowest toxicity, without impacting antitumor efficacy.Conclusions Taken together, these data point out that the rational design of improved adoptive T-cell therapies should consider the biological features of CD4 CAR-T cells, which emerged as crucial for maintaining long-term responses but also endowed by a higher toxic potential.…”
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Planning for success but facing uncertainty: lessons learned from a native oyster, Ostrea lurida, restoration project in the Salish Sea by James T. McArdle, Julie S. Barber, Sarah K. Grossman, Lindy L. Hunter

“…One of our primary objectives was to quantify the biological successes or failures of our reestablished populations. …”
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IMPLICATION OF COMMUNALISM IN CHILD-TRAINING IN ANCIENT ISRAEL AND TRADITIONAL YORUBA SETTING FOR MORAL EDUCATION IN CONTEMPORARY NIGERIA by FABAREBO SAMUEL IDOWU, IYANDA ABEL OLATOYE

“…The paper recommends that parenting should be more of a communal enterprise; it should involve the entire community and not be limited to the parents of the children. Biological parents should also appreciate communal efforts in Child-Training. …”
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Antioxidative Reactivity of L-Ascorbic Acid and D-Isoascorbic Acid Species towards Reduction of Hexachloroiridate (IV) by Han Zhang, Yanqing Xia, Peng Zhang, Liqian Hou, Ying Sun, Zhaozhan Lu, Yunfeng Tang, Hongwu Tian, Tiesheng Shi

“…The pair [IrCl6]2–/[IrCl6]3– has been demonstrated to be a good redox probe in biological systems while L-ascorbic acid (AA) is one of the most important antioxidants. …”
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Effects of Artificial Compound Feed for Live Fish Feed on Growth Performance, Nutrient Composition, Digestive Performance, and Gut Microbiota of Giant Salamander (<i>Andrias davidi... by Hongxiang Fan, Peiying Huang, Jiayi Zhu, Jiamin Li, Shaoqing Jian, Jiahao Hou, Ziyu Wang, Linjie Li, Daxian Zhao

“…The experiment was divided into three groups, each with three biological replicates. The salamander juveniles were fed artificial compound feed (S), live fish (H), and frozen fish (D) for 184 days. …”
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Comparative analysis of the whole transcriptome landscapes of muscle and adipose tissue in Qinchuan beef cattle by Ju Qiu, Zheng Ma, Zhipeng Hong, Xu Yin, Yun Chen, Hafiz Qadeer Ahmed, Linsen Zan, Anning Li

“…The results of functional enrichment analysis showed that DEMs, DELs, DECs and DEmiRs were enriched in biological processes related to development and function of muscle and fat deposition, including skeletal muscle contraction, muscle organ development, PPAR signaling pathway, fatty acid metabolism and MAPK signaling pathway. …”
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Bioelectric stimulation outperforms brain derived neurotrophic factor in promoting neuronal maturation by María del Pilar Diego-Santiago, María Ujué González, Esther María Zamora Sánchez, Nuria Cortes-Carrillo, Carlos Dotti, Francesc Xavier Guix, Sahba Mobini

“…Additionally, we address the question regarding which ES parameters regulate biological responses. The neuronal differentiation and maturation of SH-SY5Y cells were tested under several pulsed ES regimes. …”
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Cross-sectional design and protocol for Artificial Intelligence Ready and Equitable Atlas for Diabetes Insights (AI-READI) by Gerald McGwin, Linda M Zangwill, Nicholas Evans, Shannon McWeeney, Cecilia S Lee, Bhavesh Patel, Jeffrey C Edberg, Cynthia Owsley, Aaron Lee, Cecilia Lee, Sally L Baxter, Michael Snyder, Samantha Hurst, Nicole Ehrhardt, Christopher Chute, Dawn S Matthies, Julia P Owen, Amir Bahmani, Sally Baxter, Edward Boyko, Aaron Cohen, Jorge Contreras, Garrison Cottrell, Virginia de Sa, Jeffrey Edberg, Irl Hirsch, Michelle Hribar, T.Y. Alvin Liu, Bonnie Maldenado, Sara Singer, Bradley Voytek, Joseph Yracheta, Linda Zangwill

“…The fundamental rationale for promoting health resilience in T2DM stems from its high prevalence of 10.5% of the world’s adult population and its contribution to many adverse health events.Methods AI-READI is a cross-sectional study whose target enrollment is 4000 people aged 40 and older, triple-balanced by self-reported race/ethnicity (Asian, black, Hispanic, white), T2DM (no diabetes, pre-diabetes and lifestyle-controlled diabetes, diabetes treated with oral medications or non-insulin injections and insulin-controlled diabetes) and biological sex (male, female) (Clinicaltrials.org approval number STUDY00016228). …”
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Identification and validation of immune and diagnostic biomarkers for interstitial cystitis/painful bladder syndrome by integrating bioinformatics and machine-learning by Tao Zhou, Can Zhu, Wei Zhang, Qiongfang Wu, Mingqiang Deng, Zhiwei Jiang, Longfei Peng, Hao Geng, Zhouting Tuo, Zhouting Tuo, Ci Zou

“…The expression and biological functions of key genes in IC/BPS were further validated through in vitro experiments.ResultsA total of 87 DEGs were identified, comprising 43 up-regulated and 44 down-regulated genes. …”
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Pathogenic potential of ornithogenic <i>Escherichia coli</i> strains detected in the Earth's polar regions by Batyrbek I. Aslanov, Daniil V. Azarov, Maria A. Makarova, Elizaveta G. Marysheva, Lyudmila A. Kraeva, Aleksey S. Mokhov, Ekaterina A. Lebedeva, Nikita E. Goncharov, Natalya V. Lebedeva, Dmitry A. Starikov, Victoria V. Kolodzhieva, Dmitry E. Polev, Artemy E. Goncharov

“…The study used collections of E. coli isolated from ornithogenic biological material during expeditions to high latitude areas of the Arctic (archipelagos of Novaya Zemlya, Franz Josef Land, Svalbard) and Antarctic (Haswell Archipelago). 16 cultures associated with avian E. coli (12 polar and 4 temperate strains) were selected for genome-wide sequencing using BGI technology. …”
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Effect of UV-C Postharvest Disinfection on the Quality of Fresh-Cut 'Tommy Atkins' Mango by Alba Mery Garzón-García, Saúl Ruiz-Cruz, Saúl Dussán-Sarria, José Igor Hleap-Zapata, Enrique Márquez-Ríos, Carmen Lizette Del-Toro-Sánchez, José Agustín Tapia-Hernández, Dalila Fernanda Canizales-Rodríguez, Víctor Manuel Ocaño-Higuera

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ERRα promotes glycolytic metabolism and targets the NLRP3/caspase-1/GSDMD pathway to regulate pyroptosis in endometrial cancer by Pingping Su, Xiaodan Mao, Jincheng Ma, Lixiang Huang, Lirui Yu, Shuting Tang, Mingzhi Zhuang, Zhonglei Lu, Kelvin Stefan Osafo, Yuan Ren, Xinrui Wang, Xite Lin, Leyi Huang, Xiaoli Huang, Elena Ioana Braicu, Jalid Sehouli, Pengming Sun

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Predictive Modeling of Juvenile Smalltooth Sawfish Habitats: Challenges and Opportunities for Conservation by Andrea M. Kroetz, Simon Dedman, John K. Carlson

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Influence of Type of Electric Bright Light on the Attraction of the African Giant Water Bug, Lethocerus indicus (Hemiptera: Belostomatidae) by Luke Chinaru Nwosu, Luke Kosimasichukwu Nwosu

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Comparative phytochemical and pharmacological analysis of two cultivars of Annona squamosa L. cultivated in Egypt by Safaa Yassin, Samah M. Elsohafy, Amr El-Hawiet, Maged S. Abdel-Kader, Doaa A. Ghareeb, Fikria A. Darwish, Masouda E. Amer

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