Copper and iron as unique trace elements linked to fibromyalgia risk by Wenxing Zeng, Minhua Hu, Luyao Ma, Feng Huang, Ziwei Jiang

“…Future research should further validate these findings and explore the specific biological mechanisms through which Cu and Fe influence FM risk.…”
Get full text

Characterization of an Endemic Plant Origanum grosii from Morocco: Trace Element Concentration and Antihyperglycemic Activities by H. El hassouni, M. Bouhrim, R. El hajji, M. Bnouham, A. Ziyyat, A. Romane

“…Origanum genus is one of the most widely used herbs in folk medicine for its biological properties. The present investigation aims to characterize, for the first time, endemic Origanum grosii collected from the Taounate region, Morocco. …”
Get full text

CIRBP Regulates Pancreatic Cancer Cell Ferroptosis and Growth by Directly Binding to p53 by Hongqiang Gao, Ran Xie, Rong Huang, Chonglin Wang, Yue Wang, Dongdong Wang, Kaimin Liu, Conghui Yang, Qingxiong Yang, Long Chen

“…Pancreatic cancer is one of the most malignant gastrointestinal tumors, and it is of great significance to explore the molecular mechanism of its progression and find new biological therapeutic targets. CIRBP is a cold-induced protein that plays a key role in many physiological and pathological processes, but its role in pancreatic cancer is still unclear. …”
Get full text

Characterization of some selected macroalgae extracts and assessment of their insecticidal and genotoxicity in Culex pipiens L. mosquito larvae by Dina A. Refaay, Mostafa M. El-Sheekh, Yasmin M. Heikal, Ahmed A. Rashed

“…Macroalgae may be a good alternative because of their biologically active metabolites with distinctive chemical structures that have been reported for their insecticidal properties. …”
Get full text

Direct detection and identification of viruses in saliva using a SpecID ionization modified mass spectrometer. by Pierre Alusta, Angel Paredes, Marli Azevedo, Lisa Mullis, Dan Buzatu

“…Polymerase chain reaction (PCR) remains the gold standard for sensitive detection of SARS-CoV-2 infection in biological samples. However, while PCR testing for COVID is sensitive and widely used by hospitals, the method has a false-negative rate of 15-20% and is kit-based necessitating the development of alternative methods of detection that provide higher accuracy. …”
Get full text

Tożsamość i kondycja człowieka by Irena Grochowska

“…Human being who does not accept the human condition becomes undefined, he does not know his identity, he is restricted to mass, to biological body, he looks after it, improves it looking for fulfilment. …”
Get full text

Propofol Ameliorates Microglia Activation by Targeting MicroRNA-221/222-IRF2 Axis by Xi Xiao, Yuanyuan Hou, Wei Yu, Sihua Qi

“…Real-time qPCR, enzyme-linked immunosorbent assay, and Western blotting were used to identify the expression pattern of miR-221/222, inflammatory genes, cytokines, and IRF2. The biological roles and mechanisms of propofol in microglia activation were determined in BV2 cells and primary microglia. …”
Get full text

Mesalazine: a novel therapeutic agent for periodontitis via regulation of periodontal microbiota and inhibiting Porphyromonas gingivalis by Yuqi Wang, Yuqi Wang, Jun Ma, Haoyu Wang, Haoyu Wang, Jingzheng Yi, Yuxin Bai, Yuxin Bai, Min Hu, Min Hu, Jiaqing Yan, Jiaqing Yan

“…IntroductionPeriodontitis and inflammatory bowel disease are chronic inflammatory diseases with shared epidemiological, biological, and therapeutic associations. Given the similarities in their pathogenic factors, this study hypothesized that mesalazine, a key treatment agent for inflammatory bowel disease, could also be effective in managing periodontitis.MethodsThe antimicrobial effect of mesalazine on Porphyromonas gingivalis was investigated in vitro, including observations of morphological changes on the surface of P. gingivalis. …”
Get full text

Multi-dimensional evidence from the UK Biobank shows the impact of diet and macronutrient intake on aging by Chen Zhu, Youfa Wang, Xiaosong Yang, Qiran Zhao, Wenyan Xu, Xiaolu Wang, Yanjun Liang, Qihui Chen, Shenggen Fan

“…Conclusions This study underscores the significant role of diet in biological aging and provides robust evidence for the benefits of carbohydrate intake in promoting healthier aging. …”
Get full text

Decreased Spp1 Expression in Acute Myocardial Infarction after Ischemia and Reperfusion Injury by Ling Li, Jungang Huang, Zongkai Zhao, Zhuzhi Wen, Kang Li, Tianjiao Ma, Lisui Zhang, Junmeng Zheng, Shi Liang

“…In addition, Gene Ontology (GO) annotation and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses were performed to find the biological property of 449 RNAs from GSE83472 via the Database for Annotation, Visualization, and Integrated Discovery (DAVID). …”
Get full text

Signature for Pain Recovery IN Teens (SPRINT): protocol for a multisite prospective signature study in chronic musculoskeletal pain by Fiona Campbell, Jennifer Stinson, Sara E Williams, Christopher D King, Laura Simons, Massieh Moayedi, Robert C Coghill, Martin S Angst, Nima Aghaeepour, Brice Gaudilliere, Marina López-Solà, Marie-Eve Hoeppli, Emma Biggs, Ed Ganio, Kenneth R Goldschneider, Danielle Ruskin, Elliot J Krane, Suellen Walker, Gillian Rush, Marissa Heirich

“…This will facilitate risk stratification in adolescent patients with chronic MSK pain and more resourceful allocation of patients to costly and potentially burdensome multidisciplinary pain treatment approaches.Methods and analysis Here we describe a multi-institutional effort to collect, curate and analyse a high dimensional data set including epidemiological, psychometric, quantitative sensory, brain imaging and biological information collected over the course of 12 months. …”
Get full text

Specific Features of the Subjective Picture of Life as Predictors of Readiness for Innovations of Future Law Enforcement Officers by A. M. Bolshakova

“…To diagnose the peculiarities of the subjective picture of life (psycho-biological indicators), the author has used semantic time differential, the Zimbardo Time Perspective Inventory (ZTPI), and the questionnaire “Estimation of five-year intervals”. …”
Get full text

First Look at the Venoms of Two <i>Sinomicrurus</i> Snakes: Differences in Yield, Proteomic Profiles, and Immunorecognition by Commercial Antivenoms by Xiang-Yu Li, Ya-Qi Zhang, Xin-Ru Qian, Hong-Yan Zhao, Hong-Liang Lu, Jian-Fang Gao

“…Chinese coral snakes (<i>Sinomicrurus</i>) are highly neglected regarding their venom profiles and harm to humans, which impedes our ability to deeply understand their biological properties and explore their medicinal potential. …”
Get full text

Design, Synthesis, and Pharmacological Screening of Novel Porphyrin Derivatives by Ahmed A. Fadda, Rasha E. El-Mekawy, Ahmed El-Shafei, Harold S. Freeman, David Hinks, Manal El-Fedawy

“…These dyes were used as a model to study the free radical-induced damage of biological membranes and the protective effects of these porphyrins. …”
Get full text

Hypoxia-Induced GST1 Exerts Protective Effects on Trophoblasts via Inhibiting Reactive Oxygen Species (ROS) Accumulation by Lingjuan Chen, Gaoli Chen, Lixuan Guo, Yaping Wang, Chengjin Ai

“…Hypoxic conditions are a typical extrinsic factor for the modification of trophoblast biological functions, including cell proliferation, migration, and invasion. …”
Get full text

Histopathological and Immunohistochemical Features of Small to Big Satellite Nevus Uncover the Nevogenesis of Large/Giant Congenital Melanocytic Nevus by Jieyu Gu, Boxuan Wei, Bowen Gao, Ran Duan, Lingling Sheng, Danning Zheng, Yongyang Bao, Feng Xie

“…The nevogenesis of large/giant congenital melanocytic nevus (lgCMN) is a complex biological process including several integral prenatal stages. …”
Get full text

Phytochemical investigation and evaluation of antioxidant and antidiabetic activities in aqueous extracts of Cedrus atlantica by Idrissi Amine Mounadi, Mahraz Mohamed Adil, Drioua Soufiane, Assouguem Amine, Ali Essam A., Ibrahim Mohamed A., Mehta Chandra Mohan, Lahlali Rachid, Tlemcani Sara, Moussaoui Fatima, En-nabety Ghizlan, Eloutassi Noureddine, Lahkimi Amal

“…Natural compounds derived from medicinal plants offer promising avenues due to their diverse biological activities. The aim of this study was to assess the inhibitory effects of Cedrus atlantica extracts on the enzymes α-amylase and α-glucosidase, which play a crucial role in the regulation of postprandial glucose levels, as well as to investigate their phytochemical composition and antioxidant capabilities. …”
Get full text

Forensic characteristics of the offender who committed a criminal offence under Article 206-2 of the Criminal Code of Ukraine by S. V. Stetsenko

“…The first group includes general features that indicate social, demographic, and biological characteristics; the second group includes special features that characterise the personality of the offender from the perspective of the criminal offence committed and describe his or her relationship with the victim, the position held, the state of sanity at the time of the illegal act, the role and place in the criminal group, etc. …”
Get full text

Callus Formation in Fractured Femur of Rats Treated with Injection of Human Umbilical Cord Mesenchymal Stem Cell-Conditioned Medium by Marla Anggita, Widagdo Sri Nugroho, Yuda Heru Fibrianto, Setyo Budhi, Teguh Budipitojo

“…Mesenchymal stem cells-conditioned medium (MSC-CM) is the extraction from stem cell medium containing biological substances, including growth factors and cytokines. …”
Get full text

Plant breeding evaluation of the red currant cultivar ‘Podarok Pobeditelyam’ and its inbred progeny by O. D. Golyaeva, O. V. Panfilova, O. V. Kalinina

“…The purpose of this study was to assess the breeding potential of the red currant cultivar ‘Podarok Pobeditelyam’ by disclosing economic and biological characteristics in its inbred progeny.Methods and materials. …”
Get full text