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16901
Immunoinfiltration Analysis of Mitochondrial Damage‐Related Genes in Lung Adenocarcinoma and Construction of a Classification and Prognostic Model Integrated With WGCNA and Machine...
Published 2025-01-01“…Functional enrichment analyses were conducted to explore biological functions and signaling pathways. Gene modules related to clinical stages of LUAD were identified by WGCNA. …”
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16902
Exploring serum miR-33b as a novel diagnostic marker for hypercholesterolemia and obesity: insights from a pilot case-control study
Published 2025-01-01“…MicroRNAs (miRNAs) are small, conserved, non-coding RNA sequences consisting of approximately 22 nucleotides, playing crucial roles in biological and pathological functions. Among these, miR-33a/b is particularly associated with metabolic diseases, notably obesity and atherosclerosis. …”
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16903
Spectroscopic, DFT, anti-bacterial, and in-silico investigations of novel semicarbazone and thiosemicarbazone synthesised from asymmetrical chalcones
Published 2025-04-01“…The findings suggested that thiosemicarbazones and semicarbazones possess favorable interaction patterns and binding energies. The biological capacity of each molecule to inhibit bacterial strains exhibited variability in the evaluation of the compounds' in vitro antibacterial efficacy. …”
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16904
Deregulated methylation and expression of PCDHGB7 in patients with non-small cell lung cancer: a novel prognostic and immunological biomarker
Published 2025-01-01“…Its function in lung cancer has not been elucidated.MethodsWe comprehensively investigated PCDHGB7 expression, prognosis, biological function, methylation patterns, and it’s relationship with immune infiltration and immunotherapy response through public datasets (HPA, TCGA, GEO, OncoDB and MEXPRESS). …”
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16905
New genetic tools for plant defense against parasitic nematodes
Published 2021-06-01“…The Golden Potato Cyst Nematode (G. rostochiensis, GPCN) may be taken as an example of an economically important pest: in Russia, it occurs in 61 regions with a total area of 1.8 million ha and may cause the yield loss from 19 to 90 %. The biological characteristics of sedentary nematodes makes their agrotechnical control problematic, i.e. the GPCN cysts remain dormant in soil for many years until a susceptible host appears, whereas nematicides are either toxic or inefficient. …”
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16906
Association of Self-DNA Mediated TLR9-Related Gene, DNA Methyltransferase, and Cytokeratin Protein Expression Alterations in HT29-Cells to DNA Fragment Length and Methylation Statu...
Published 2013-01-01“…To understand the biologic role of self-DNA bound to Toll-like Receptor 9 (TLR9), we assayed its effect on gene and methyltransferase expressions and cell differentiation in HT29 cells. …”
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16907
Effects of Traumeel (Tr14) on Exercise-Induced Muscle Damage Response in Healthy Subjects: A Double-Blind RCT
Published 2016-01-01“…The present double-blind, randomized, placebo-controlled clinical trial intended to test whether ingestion of a natural combination medicine (Tr14 tablets) affects serum muscle damage and inflammatory immune response after downhill running. 96 male subjects received Tr14 tablets, which consist of 14 diluted biological and mineral components, or a placebo for 72 h after the exercise test, respectively. …”
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16908
The Effect of the Glucosinolate Sinigrin on Alterations in Molecular Biomarkers of the Myocardium in Swiss Mice
Published 2025-01-01“…Glucosinolates are chemically stable compounds that exhibit biological activity in the body following hydrolysis catalyzed by the enzyme myrosinase. …”
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16909
Fully Automated Bone Age Assessment on Large-Scale Hand X-Ray Dataset
Published 2020-01-01“…Bone age assessment (BAA) is an essential topic in the clinical practice of evaluating the biological maturity of children. Because the manual method is time-consuming and prone to observer variability, it is attractive to develop computer-aided and automated methods for BAA. …”
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16910
Competitive exclusion in an infection-age structured vector-host epidemic model
Published 2017-07-01“…The formulas for the reproduction numbers $\mathcal R^j_0$ of strain $j,j=1,2,···, n$ , are obtained from the biological meanings of the model. The strain $j$ can not invade the system if $\mathcal R^j_0 \lt 1$ , and the disease free equilibrium is globally asymptotically stable if $\max_j\{\mathcal R^j_0\} \lt 1$ . …”
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16911
Benchtop 1H NMR spectroscopy as a practical tool for characterization of chemically ex-changing systems in Ascorbic acid
Published 2021-03-01“…L-Ascorbic acid (AA) which is an important substrate for body and biological reac-tions was chosen as a target model molecule. …”
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16912
Stapled End-To-Side Ileocolic Anastomosis in Crohn’s Disease: Old Dog, Reliable Tricks? A Retrospective Two-Center Cohort Study
Published 2024-03-01“…Before surgery, 80% were exposed to at least 1 cycle of systemic steroids and 71% had at least 1 biologic agent; 60% exhibited penetrating disease and 38% developed an intra-abdominal abscess. …”
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16913
Addressing challenges in vector control: a review of current strategies and the imperative for novel tools in India’s combat against vector-borne diseases
Published 2024-07-01“…These range from chemical insecticides used in indoor residual sprays, space sprays, fogging, treated bednets and larvicides to biological control methods such as larvivorus fishes and environmental control and modification measures such as source reduction. …”
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16914
Efficacy And Safety Of Low Dose Tofacitinib As Induction Therapy In Moderate To Severe Ulcerative Colitis: A Pilot Study
Published 2024-12-01“…Conclusion: Low-dose Tofacitinib is an effective option in the treatment of moderate to severe ulcerative colitis offering efficacy comparable to biologics with lesser side effects, no loss of efficacy over time and cost-effectiveness Keywords: Ulcerative Colitis, Inflammation. …”
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16915
Mycological Profile and Associated Factors Among Patients with Dermatophytosis in Astana, Kazakhstan
Published 2025-01-01“…Data were gathered through questionnaires and medical records were reviewed. Biological samples were cultured on Sabouraud dextrose agar, and PCR was employed to assess the genetic diversity of strains. …”
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16916
MHC Class 1 and PDL-1 Status of Primary Tumor and Lymph Node Metastatic Tumor Tissue in Gastric Cancers
Published 2019-01-01“…These results reveal different biological characteristics of primary and metastatic tumor cells.…”
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16917
Investigating the Effect of Virtual Education on Students' Learning
Published 2023-03-01“…However, virtual education negatively impacts religious growth and moral development, economic and professional education, scientific and technological development, social and political education, biological and physical education, teacher role, educational environment, and evaluation. …”
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16918
The Effect of Supplementing Mushroom Growing Substrates on the Bioactive Compounds, Antimicrobial Activity, and Antioxidant Activity of Pleurotus ostreatus
Published 2022-01-01“…Pleurotus ostreatus mushroom contains important bioactive compounds and has several biological activities; however, mushroom growing substrates have major influence on chemical and functional characteristics of the mushroom. …”
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16919
Avolition Characterizes the Chronic Fatigue Experienced in Quiescent Inflammatory Bowel Disease
Published 2025-01-01“…<b>Conclusions:</b> To tackle the question of fatigue in IBD, research should consider investigating the biological mechanisms implicating intestinal physiopathology of IBD in the impairment of brain structure involved in motivation. …”
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16920
Diel changes in the expression of a marker gene and candidate genes for intracellular amorphous CaCO3 biomineralization in Microcystis
Published 2025-02-01“…While we ignore the biological function of iACC and the molecular mechanisms driving their formation, this process may impact local geochemical cycles and/or be used for bioremediation strategies. …”
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