Exploring the link between soil health and crop productivity by Yingying Xing, Xiukang Wang, Adnan Mustafa

“…By examining the physical, chemical, and biological properties of soil, it uncovers the key limitations posed by the soil environment on crop growth. …”
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Patchoulene Epoxide Isolated from Patchouli Oil Suppresses Acute Inflammation through Inhibition of NF-κB and Downregulation of COX-2/iNOS by Jia-Li Liang, Jia-Zhen Wu, Yu-Hong Liu, Zhen-Biao Zhang, Qi-Duan Wu, Han-Bin Chen, Yan-Feng Huang, Yao-Xing Dou, Jiang-Tao Zhou, Zi-Ren Su, Janis Ya-Xian Zhan

“…According to the GC-MS analysis, compositional variation was observed between samples of patchouli oil, of which an unknown compound identified as patchoulene epoxide (PAO) was found only in the long-stored oil, whose biological activity still remains unknown. Therefore, the present study aimed to evaluate the potential anti-inflammatory activity with three in vivo inflammatory models: xylene-induced ear edema, acetic acid-induced vascular permeability, and carrageenan-induced paw edema. …”
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Analysis of Circulating MicroRNAs In Vivo following Administration of Dexamethasone and Adrenocorticotropin by Ivan Igaz, Gábor Nyírő, Zoltán Nagy, Henriett Butz, Zsolt Nagy, Pál Perge, Peter Sahin, Miklós Tóth, Károly Rácz, Peter Igaz, Attila Patócs

“…Conclusions. hsa-miR-27a expression is modulated by hormones of the hypothalamic-pituitary-adrenal axis both in vitro and in vivo. The biological relevance of hsa-miR-27a modulation by hormones is unclear, but the responsiveness of circulating microRNAs to hormones of the pituitary-adrenal axis is noteworthy.…”
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Synthesis, Antimalarial Activity and Molecular Dynamics Studies of Pipecolisporin: A Novel Cyclic Hexapeptide with Potent Therapeutic Potential by Nety Kurniaty, Taufik Muhammad Fakih, Rani Maharani, Unang Supratman, Ace Tatang Hidayat, Nurhidanatasha Abu Bakar, Xiaoshuang Wei

“…Pipecolisporin, a cyclic hexapeptide isolated from <i>Nigrospora oryzae</i>, has emerged as a promising antimalarial candidate due to its potent biological activity and stability. This study explores the synthesis, antimalarial activity, and computational studies of pipecolisporin, aiming to better understand its therapeutic potential. …”
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RNA Virus Discovery Sheds Light on the Virome of a Major Vineyard Pest, the European Grapevine Moth (<i>Lobesia botrana</i>) by Humberto Debat, Sebastian Gomez-Talquenca, Nicolas Bejerman

“…Furthermore, the identification of a carmotetravirus branching in the same cluster as the Providence virus, a lepidopteran virus which replicates in plants, raises questions regarding the biological significance of this moth virus to the grapevine host. …”
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Effect of High, Medium, and Low Molecular Weight Hyaluronan on Inflammation and Oxidative Stress in an In Vitro Model of Human Nasal Epithelial Cells by Giusy Daniela Albano, Anna Bonanno, Luca Cavalieri, Eleonora Ingrassia, Caterina Di Sano, Liboria Siena, Loredana Riccobono, Rosalia Gagliardo, Mirella Profita

“…The aim of this study was to investigate the pro- or anti-inflammatory biologic function of HA at different molecular weight in an in vitro model of nasal inflammation IL-17A mediated. …”
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Molecular Modeling and Simulation Analysis of Antimicrobial Photodynamic Therapy Potential for Control of COVID-19 by Maryam Pourhajibagher

“…In this in silico study, SARS-CoV-2-SG was selected as a novel target for curcumin as a photosensitizer during aPDT to exploit its physicochemical properties, molecular modeling, hierarchical nature of protein structure, and functional analysis using several bioinformatics tools and biological databases. The results of a detailed computational investigation revealed that SARS-CoV-2-SG is most similar to 6VXX_A, with 100% query cover and identity. …”
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Modulatory Effect of 1,25-Dihydroxyvitamin D3 on IL1β-Induced RANKL, OPG, TNFα, and IL-6 Expression in Human Rheumatoid Synoviocyte MH7A by Xiaoke Feng, Chengyin Lv, Fang Wang, Ke Gan, Miaojia Zhang, Wenfeng Tan

“…In summary, although it has a biological function to induce RANKL expression, 1,25(OH)2D3 could upregulate OPG/RANKL ratio and mediate anti-inflammatory action in an inflammatory milieu of synoviocyte, contributing to the inhibition of inflammation-induced osteoclastogenesis in RA.…”
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Breeding for disease resilience: opportunities to manage polymicrobial challenge and improve commercial performance in the pig industry by Xuechun Bai, Graham S. Plastow

“…However, little progress has been made to date in the application of disease resilience in breeding programs due to a number of factors, including (1) confusion around definitions of disease resilience and its component traits disease resistance and tolerance, and (2) the difficulty in characterizing such a complex trait consisting of multiple biological functions and dynamic elements of rates of response and recovery from infection. …”
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Differences and analogies in thyroid cancer discovered incidentally or by thyroid-related screening: a multicenter study by Laura Croce, Rosaria Maddalena Ruggeri, Camilla Virili, Carlo Cappelli, Marsida Teliti, Pietro Costa, Spyridon Chytiris, Antonio Nicocia, Francesca Coperchini, Maria Flavia Bagaglini, Flavia Magri, Alfredo Campennì, Mario Rotondi

“…No significant differences could be observed in terms of TC histotype, cancer size, extrathyroidal extension, lymph node metastases, AJCC staging or American Thyroid Association (ATA) risk stratification. Conclusions: Biological features of TC are similar in the TD and ID groups, but patients in the two groups display significant differences regarding their clinical features.…”
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Maternal Role in Adolescent Mothers with Infants by Belkis Sánchez Martínez, Daniela Lizeth Luna Rodríguez, Nairovys Gómez Martínez

“…<strong>Background:</strong> breastfeeding is a natural biological process in women during pregnancy and its purpose is to feed and protect the newborn baby up to six months of age. …”
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A low-cost printed circuit board-based centrifugal microfluidic platform for dielectrophoresis by Nicklas Rondot, Songyuan Yan, Dario Mager, Lawrence Kulinsky

“…Abstract In recent decades, electrokinetic handling of microparticles and biological cells found many applications ranging from biomedical diagnostics to microscale assembly. …”
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Heterogeneous graph convolutional neural network for protein-ligand scoring by Kevin Crampon, Alexis Giorkallos, Xavier Vigouroux, Stephanie Baud, Luiz Angelo Steffenel

“…Using a representation that involves classical graph neural networks (GNNs) and splitting the learning process regarding the edge type makes the proposed model to be the best adapted for future transfer learning on other (protein-DNA, protein-sugar, protein-protein, etc.) biological complexes.…”
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Cyclooxygenase-2 Expression Is a Predictive Marker for Late Recurrence in Colorectal Cancer by Sung Hoo Kim, Byung Kyu Ahn, Seung Sam Paik, Kang Hong Lee

“…However, data about the relation between COX-2 expression and the impact on the biologic behavior of recurrent disease are inconclusive as yet. …”
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Informative EST-SSR markers for genotyping and intraspecific differentiation of Brassica oleracea var. capitata L. by M. N. Shapturenko, T. V. Pechkovskaya, S. I. Vakula, A. V. Jakimovich, Yu. M. Zabara, L. V. Khotyleva

“…Brassica oleraceae var. capitata L. is characterized by a high level of intraspecific heterogeneity due to some biological features that cause difficulties for breeding creating genetically homogenous forms and maintaining their genetic purity. …”
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A Mathematical Model for the Within-Host Dynamics of Malaria Parasite with Adaptive Immune Responses by Jemal Muhammed Ahmed, Getachew Tashome Tilahun, Shambel Tadesse Degefa

“…We establish the well-posedness and biological feasibility of the model in terms of proving the non-negativity and boundedness of solutions. …”
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The role of HSPA14 in breast cancer: implications for tumorigenesis, immune response modulation, and personalized therapies by Ruipeng Zhao, Xiaocun Zhu, Wan Wei, Linlin Zhen

“…GSEA analysis was conducted to identify the biological function of HSPA14. Spearman’s correlation analysis was performed to examine the correlation between HSPA14 expression and immune cell infiltration, as well as immune checkpoint genes. …”
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FEAR PHENOMENON IN EXISTENTIAL PHILOSOPHY by V. V. Melnyk

“…The fear is interpreted here as a result of direct physical stimulation of biological reactions within the human body in response to external stimuli (real or imaginary). …”
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Passage through phenophases by milkvetches introduced into the environments of the Kulunda Steppe by T. V. Kornievskaya

“…Accurate forecasts for biological responses of plant species to climate change require profound understanding of the impact produced by meteorological factors on plant phenology.Materials and methods. …”
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Analysis of Prey-Predator Scheme in Conjunction with Help and Gestation Delay by M. Mukherjee, D. Pal, S. K. Mahato, Ebenezer Bonyah, Ali Akbar Shaikh

“…We have also addressed critically the biological implications of our analytical findings with proper numerical examples.…”
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