Identification of the immune infiltration and biomarkers in ulcerative colitis based on liquid–liquid phase separation-related genes by Zhixing Hong, Shilin Fang, Haihang Nie, Jingkai Zhou, Yuntian Hong, Lan Liu, Qiu Zhao

“…Two distinct clusters were identified, in which cluster A displayed higher immune infiltration level compared with the cluster B. The top targeted biological pathways of two clusters were distinct, glutamate receptor antagonist ranked top for cluster A while HDAC inhibitor ranked top in cluster B. …”
Get full text

Neural activity responsiveness by maturation of inhibition underlying critical period plasticity by Ibuki Matsumoto, Sou Nobukawa, Sou Nobukawa, Sou Nobukawa, Sou Nobukawa, Takashi Kanamaru, Takashi Kanamaru, Yusuke Sakemi, Yusuke Sakemi, Nina Sviridova, Nina Sviridova, Tomoki Kurikawa, Nobuhiko Wagatsuma, Kazuyuki Aihara, Kazuyuki Aihara

“…In the present study, we aimed to investigate neuronal activity responsiveness with respect to the maturation of inhibition at gamma-band frequencies.MethodWe calculated inter-trial phase coherence (ITPC), which quantifies event-related phase modulations across trials, using a biologically plausible spiking neural network that generates gamma oscillations through interactions between excitatory and inhibitory neurons.ResultsOur results demonstrated that the neuronal response coherence to external periodic inputs exhibits an inverted U-shape with respect to the maturation of inhibition. …”
Get full text

Genome Mining and Characterization of Two Novel <i>Lacticaseibacillus rhamnosus</i> Probiotic Candidates with Bile Salt Hydrolase Activity by Gianluigi Agolino, Marianna Cristofolini, Amanda Vaccalluzzo, Davide Tagliazucchi, Alice Cattivelli, Alessandra Pino, Cinzia Caggia, Lisa Solieri, Cinzia Lucia Randazzo

“…Bile salt hydrolase (BSH; EC 3.5.1.24) is the microbial enzyme that catalyzes the conversion of primary bile acids (BAs) into secondary ones, promoting microbial adaptation and modulating several host’s biological functions. Probiotics with BSH activity are supposed to survive harsh intestinal conditions and exert a cholesterol-lowering effect. …”
Get full text

PLGA confers upon conventional nonfluorescent molecules luminescent properties to trigger 1O2-induced pyroptosis and immune response in tumors by Lan Zou, Rujing Wang, Mengnan Zhao, Yuke Li, Chen Sun, Jinjin Xie, Yan Chen, Qian Jing, Dandan Mi, Sanjun Shi

“…Simultaneously, our findings highlight PLGA-NPs as a novel optical formulation suitable for imaging, displaying substantial biological activity when paired with photoirradiation. …”
Get full text

Integrated bioinformatic approach of Balur therapy for breast cancer subtypes by Aristyani Sherry, Subagjo Saraswati, Rahayu Tintrim, Sumitro Sutiman B.

“…This study was to describe the complexity of Balur in the biological system of breast cancer subtypes such as luminal A, liminal B, and HER-2, which had been found in high numbers in Indonesia, with an integrative bioinformatic approach. …”
Get full text

HISTORY OF HIGHLY PATHOGENIC AVIAN INFLUENZA ERADICATION IN RUSSIAN FEDERATION IN 2016–2017 by M. S. Volkov, V. N. Irza, A. V. Varkentin

“…Basic attention is given to the destruction of poultry died and stamped out during implementation of anti-epidemic measures, and potential alternative ways of biological waste destruction are demonstrated. Principal risks of introduction of emerging influenza virus subtypes into the Russian Federation are determined. …”
Get full text

Stimuli-responsive hydrogel dressing for wound healing by Wei Zhang, Jun Hu, Hao Wu, Xiufei Lin, Limei Cai

“…We introduce the design scheme of stimulus-response hydrogels in detail based on the local wound biological/biochemical peculiarities (pH, reactive oxygen species glucose, and enzymes, etc.) and physical microenvironments (temperature, light, ultrasound, and electric fields, etc.). …”
Get full text

About a Large Botryoid Rhabdomyosarcoma in a Little Girl: Management Difficulties and Literature Review by Dehi Boston Mian, Vedi Andre Serges Loue, Sylvanus Koui

“…This allows pathologic, genetic, and biological characterization of nonmetastatic botryoid rhabdomyosarcoma. …”
Get full text

Recent advances in genetics of aggressive behavior by J. D. Davydova, S. S. Litvinov, R. F. Enikeeva, S. B.  Malykh, E. K. Khusnutdinova

“…However, environmental risk factors, mental illness and somatic diseases can lead to increased aggression to be the biological basis of antisocial behavior in a human society. …”
Get full text

DIDACTIC TERMS OF USE OF BIOGRAPH INFINITI SPECIALIZED SOFTWARE IN UKRAINE’S HIGHER EDUCATION INSTITUTIONS by Olha M. Lunhol, Olha A. Haborets, Hanna M. Kolieva, Artur O. Voloboiev

“…Each laboratory work is created according to the principles of scientificity, integrity and professional orientation of education and includes 3 levels: general (basic), psychological and medical-biological. …”
Get full text

Heterologous expression of SpsTAC2 in Arabidopsis affected branch angle and secondary vascular system development by Fangshu Niu, Mengru Yuan, Hongxia Zhao, Zhi Pang, Jie Yan, RuiXie Ning, Lin Shi, Fengqiang Yu, Dongshan Wei, Rong Yang, Runming Zhang, Haifeng Yang

“…To investigate the biological functions of Tiller Angle Control 2 (TAC2) in Salix psammophila. …”
Get full text

Gene mutation, clinical characteristics and pathology in resectable lung adenocarcinoma by Ji’an Zou, Wei Han, Yan Hu, Chao Zeng, Jina Li, Weixuan Lei, Jieming Cao, Quanming Fei, Mengqi Shao, Junqi Yi, Zeyu Cheng, Li Wang, Fang Wu, Wenliang Liu

“…Conclusion Special pathological components (mucinous, neuroendocrine, and poor-differentiated) and gene mutations had an influence on biological behavior of tumors, resulting in different clinical characteristics and prognosis.…”
Get full text

Alcohol Inhibits Odontogenic Differentiation of Human Dental Pulp Cells by Activating mTOR Signaling by Wei Qin, Qi-Ting Huang, Michael D. Weir, Zhi Song, Ashraf F. Fouad, Zheng-Mei Lin, Liang Zhao, Hockin H. K. Xu

“…However, the role of ethanol (EtOH) in the biological functions of human dental pulp cells (DPCs) is unknown. …”
Get full text

The modulating effect of circulating carbohydrate antigen 125 on ST2 and long-term recurrent morbidity burden by Elena Revuelta-López, Rafael de la Espriella, Gema Miñana, Enrique Santas, Sandra Villar, Juan Sanchis, Antoni Bayés-Genís, Julio Núñez

“…These results highlight a potential biological interaction between sST2 and CA125, suggesting that CA125 status may refine the prognostic utility of sST2 in AHF. …”
Get full text

Tannins for food preservation and human health: A review of current knowledge by Yesim Ozogul, Yilmaz Ucar, Eskindir Endalew Tadesse, Nikheel Rathod, Piotr Kulawik, Monica Trif, Tuba Esatbeyoglu, Fatih Ozogul

“…The phenolic structure of tannins has also the potential to be used in food, nutraceutical and pharmaceutical industries.Tannins exhibit a high level of biological activity. Therefore, a number of advantages such as antioxidant, anticancer, anti-allergic, and antimicrobial properties, have been verified in recent research. …”
Get full text

Link of dragonflies and damselflies with the aquatic environment is differently expressed in adult and larval stages by Edwin THM. Peeters, Anton AM. Gerritsen, Froukje Rienks, Michiel Wilhelm

“…Damselfly larvae were associated with a moderate to reasonable biological water quality and dragonfly larvae with reasonable to good. …”
Get full text

The impaired response of nasal epithelial cells to microplastic stimulation in asthma and COPD by Magdalena Paplińska-Goryca, Paulina Misiukiewicz-Stępień, Monika Wróbel, Katarzyna Mycroft-Rzeszotarska, Dorota Adamska, Julia Rachowka, Milena Królikowska, Krzysztof Goryca, Rafał Krenke

“…This study aimed to evaluate the biological effects of polyamide fibres on nasal epithelium co-cultivated with macrophages in control, asthma, and COPD groups. …”
Get full text

Competitive interactions for food resources between invasive Ponto-Caspian gobies and their native competitors in the context of global warming by Piotr Kłosiński, Jarosław Kobak, Tomasz Kakareko

“…Climate warming can modify the process of biological invasions by affecting the outcomes of competition between alien species and their native counterparts in invaded environments. …”
Get full text

Case Report: Combined Autoimmune Pancreatitis, Ulcerative Colitis and Sclerosing Cholangitis in 28-y.o. Patient by A. R. Khurmatullina, A. V. Okhlobystin, L. N. Androsova, R. T. Rzayev, A. S. Tertychnyy, A. P. Kiryukhin, O. Z. Okhlobystina, M. S. Zharkova, O. S. Shifrin, V. T. Ivashkin

“…The patient was recommended to receive biologic therapy for UC remission induction.Conclusion. …”
Get full text

Arthropod bioindicators of environmental quality by Márcia Soares Spiller, Claiton Spiller, Juliana Garlet

“…In short, because they respond quickly, the changes are considered to be efficient biological indicators; therefore, knowing the diversity of species and their degree of interaction with the environment allows us to analyze the effects of anthropic modifications in ecosystems.…”
Get full text