Recent advances in the management of knee osteoarthritis: a narrative review by Viktor Shtroblia, Pavlo Petakh, Iryna Kamyshna, Iryna Halabitska, Oleksandr Kamyshnyi

“…Nonpharmacological treatments, such as transcutaneous electrical nerve stimulation (TENS), acupuncture, and local heat therapy, provide variable pain relief and should be customized based on individual patient responses. Targeted biologic agents, such as antibodies to TNF-α, IL-1, and NGF, hold promise for more precise pain relief; however, further research is required to establish their routine use. …”
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Protein Ubiquitylation in Pancreatic Cancer by Thomas Bonacci, Julie Roignot, Philippe Soubeyran

“…Whereas it has been known for more than 3 decades now, ubiquitylation is a post-translational modification of protein that only recently emerged as a major regulator of many biological functions, dependent and independent on the proteasome, whose failure is involved in many human diseases, including cancer. …”
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Antimicrobial Applications of Transition Metal Complexes of Benzothiazole Based Terpolymer: Synthesis, Characterization, and Effect on Bacterial and Fungal Strains by Mohamed A. Riswan Ahamed, Raja S. Azarudeen, N. Mujafar Kani

“…Thermal degradation model of the terpolymer and its metal complexes was also proposed using PD method. Biological activities of the ligand and its complexes were tested against Shigella sonnei, Escherichia coli, Klebsiella species, Staphylococcus aureus, Bacillus subtilis, and Salmonella typhimurium bacteria and Aspergillus flavus, Aspergillus niger, Penicillium species, Candida albicans, Cryptococcus neoformans, Mucor species fungi.…”
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Ferroptosis-Related Transcriptional Level Changes and the Role of CIRBP in Glioblastoma Cells Ferroptosis by Zijiang Yang, Ting Zhang, Xuanlin Zhu, Xiaobiao Zhang

“…We further unraveled the biological functions and clinical implications of cold-inducible RNA-binding protein (CIRBP) in the context of glioblastoma by using a multifaceted approach, encompassing gene expression profiling, survival analysis, and functional assays to elucidate its role in glioblastoma cell mortality and its potential influence on patient prognosis. …”
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Host plants selection of Centranthera grandiflora Benth. and nontargeted metabolomics analysis of its parasitic and non-parasitic samples. by Song Jin, Yuchuan Li, Jun Ni, Haili Xie, Falin Lei, He Liu

“…The experiments of mixed sowing of C. grandiflora and 9 companion plants that might be hosts were conducted, and the growth, biological yield and other indexes were observed. The results showed that Cyperus iria L. was the best host for C. grandiflora, and when they were mixed sowed, C. grandiflora had a vigorous growth above ground and the haustoria connected obviously below ground, while C. grandiflora could achieve blossoming and fruiting in the same year. …”
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Nature of viruses and the radical change in viral taxonomy by V. V. Makarov, L. P. Buchatsky

“…Co-evolution of the viral and cellular genomes includes mutual horizontal gene transfer and joint development of new biological functions, such as the mechanism of phylogenesis and phylodynamics of coactants. …”
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Microscale insight into the proton concentration during electrolytic reaction via an optical microfiber: potential for microcurrent monitoring by a dielectric probe by Yunyun Huang, Jiaxuan Liang, Haotian Wu, Pengwei Chen, Aoxiang Xiao, Bai-Ou Guan

“…Abstract Local microcurrent monitoring is of great significance for biological and battery systems, yet it poses a formidable challenge. …”
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A New Preprocessing Method for Diabetes and Biomedical Data Classification by Sarbast CHALO, İbrahim Berkan AYDİLEK

“…Several different types of machine learning classifiers, such as KNN, J48, RF, and DT, were utilized in the experimental findings of biological datasets. The findings that were obtained demonstrated that our trainable model is capable of correctly classifying biomedical data. …”
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Uranium phytoremediation by Helianthus annuus L. and Amaranthus caudatus L. plants by Majid Mahdieh, Mohammedreza Sangi, Saeid Hamidi, Seyed M. Talebi, Alex V. Matsyura

“…Uranium contamination presents significant challenges to biological systems due to its chemical toxicity and radiological impacts. …”
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Highly Proliferative Immortalized Human Dental Pulp Cells Retain the Odontogenic Phenotype when Combined with a Beta-Tricalcium Phosphate Scaffold and BMP2 by Xiangfen Li, Liu Wang, Qin Su, Ling Ye, Xuedong Zhou, Dongzhe Song, Dingming Huang

“…To overcome these challenges, we successfully immortalized human dental pulp cells using the piggyBac system which was employed to efficiently overexpress the SV40 T-Ag, and we then comprehensively described the cell biological behavior. The immortalized human dental pulp cells (iHDPCs) acquired long-term proliferative activity and expressed most HDPC markers. …”
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Rapid life-history evolution reinforces competitive asymmetry between invasive and resident species by Chapuis, Elodie, Jarne, Philippe, David, Patrice

“…Biological invasions by phylogenetically and ecologically similar competitors pose an evolutionary challenge to native species. …”
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Protective Effects of Chitosan Oligosaccharide Against Lipopolysaccharide-Induced Inflammatory Response and Oxidative Stress in Bovine Mammary Epithelial Cells by Ziwei Lin, Yanlong Zhou, Ruiwen Chen, Qiuyan Tao, Qiwen Lu, Qianchao Xu, Haibin Yu, Ping Jiang, Zhihui Zhao

“…COS has a variety of biological functions, including anti-inflammatory and antioxidant activities. …”
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Powering Implanted Devices Wirelessly Using Spider-Web Coil by Amal Ibrahim Mahmood, Sadik Kamel Gharghan, Mohamed A.A. Eldosoky, Ahmed M. Soliman

“… Implantable biomedical (IBM) systems and biomedical sensors can improve life quality, identify sickness, monitor biological signs, and replace the function of malfunctioning organs. …”
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Impact of war on the environment: ecocide by Yohannes Desalegn Wirtu, Umer Abdela

“…This paper reviews the militaristic consequences on Mother Earth and in particular ecocide or the mass degradation of the biological forms in regards to war. Wars are recorded from the ancient Egyptian dynasty to the modern era, and all are left concerning effects on mother nature such as deforestation, loss of biodiversity, soil erosion, and water, and air pollution. …”
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Health Care for the Elderly People by María Aveiga Hidalgo, Clara Elisa Pozo Hernández, Olga Mireya Alonzo Pico, Erika León León

“…<strong>Background:</strong> during the aging process, biological, psychological changes and in the social role of the individual are generated, conditions that require special care. …”
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Integrated and streamlined microfluidic device for molecular diagnosis of pathogen through direct PCR amplification by Dohwan Lee, Tae Seok Seo

“…Direct PCR, which enables direct DNA amplification from biological samples without the need for DNA extraction and purification, streamlines the device architecture and transforms it into a more user-friendly form. …”
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The Effect of Crank Length Changes from Cycling Rehabilitation on Muscle Behaviors by Lu Zongxing, You Shengxian, Wei Xiangwen, Chen Xiaohui, Jia Chao

“…In addition, the relationship between crank length and muscle biological force was analyzed with the AnyBody Modeling System™, a human simulation modeling software based on the Hill-type model. …”
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TDP43 augments astrocyte inflammatory activity through mtDNA-cGAS-STING axis in NMOSD by Zhuhe Liu, Yunmeng Bai, Bingtian Xu, Haixia Wen, Kechun Chen, Jingfang Lin, Yuanyuan Wang, Jiangping Xu, Haitao Wang, Fudong Shi, Jigang Wang, Honghao Wang

“…Here, our observations demonstrate an upregulation of TDP43 in both in vitro and in vivo models of NMOSD, as well as in biological samples from NMOSD patients. Single-nucleus RNA sequencing revealed that NMOSD induced A1-like reactive astrocytes and astrocyte mitochondrial dysfunction in mice. …”
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Controversial Roles of Regenerating Family Proteins in Tissue Repair and Tumor Development by Luting Yu, Qingyun Wu, Shenglong Jiang, Jia Liu, Junli Liu, Guoguang Chen

“…<b>Background</b>: Over the past 40 years since the discovery of regenerating family proteins (Reg proteins), numerous studies have highlighted their biological functions in promoting cell proliferation and resisting cell apoptosis, particularly in the regeneration and repair of pancreatic islets and exocrine glands. …”
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Helicobacter pylori promotes intestinal flora imbalance and hepatic metabolic disorders under arsenic stress by Linmin Zhong, Qiling Yang, Yiming Shao, Shanwen Hu, Lianxian Guo

“…Herein, we hypothesize that H. pylori infection may exacerbate the intestinal flora imbalance and hepatic metabolic disturbances caused by arsenic exposure, which may disrupt enterohepatic homeostasis and potentially increase biological susceptibility to heavy metal toxicity.…”
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