On optimization of substrate removal in a bioreactor with wall attached and suspended bacteria by Alma Mašić, Hermann J. Eberl

“…Instead, we solve the simpler problem to optimize reactor performance in the class of off-on functions, a choice that is motivated by the underlying biological process. These control functions start with an initial no-flow period and then switch to a constant flow rate until the buffer vessel is empty. …”
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Characterization of the circadian typology in university students in relation to the type of career by Arlan Machado Rojas, Yunier Broche Pérez, Osvaldo Norman Montenegro, María Elena de la Torre Santos, Daniel Tirado Saura, Carolina Machado de la Torre

“…<p><strong>Foundation</strong>: Chronotype is an attribute of human beings, which reflects its individual circadian phase, and affects biological and psychological functions, both in health and disease. …”
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L-Proline-Catalyzed Synthesis of Phthalimide Derivatives and Evaluation of Their Antioxidant, Anti-Inflammatory, and Lipoxygenase Inhibition Activities by Shagufta Perveen, Raha Orfali

“…A study was planned to synthesize the phthalimide derivatives as phthalimides have versatile biological activities. To synthesize the phthalimide derivatives, initially the reaction was optimized with various catalysts, and L-proline was found to be the best catalyst as it provided excellent yield. …”
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In Silico Evolution of Gene Cooption in Pattern-Forming Gene Networks by Alexander V. Spirov, Marat A. Sabirov, David M. Holloway

“…We use a data-driven model of insect segmentation, for the fruit fly Drosophila, and evaluate fitness by robustness to maternal variability—a major constraint in biological development. We compare two mechanisms of gene cooption: a simpler one with gene Introduction and Withdrawal operators; and one in which GRN elements can be altered by transposon infection. …”
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Exploring the feasibility and clinical impact of ultrasound microvascular flow imaging in detecting brain injury in hyperbilirubinemia neonates by Shuang He, Meiyu Wang, Man Zhu, Min Zhang, Xueni He, Xiang Jiang, Shu Tang, Zhaoxia Wang

“…These methods may serve as potential biological markers for the early assessment of bilirubin-induced brain damage.…”
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Cellular Response to a Novel Fetal Acellular Collagen Matrix: Implications for Tissue Regeneration by Robert C. Rennert, Michael Sorkin, Ravi K. Garg, Michael Januszyk, Geoffrey C. Gurtner

“…PriMatrix implants were found to go through a biological progression initiated by a transient infiltrate of inflammatory cells, followed by mesenchymal cell recruitment and vascular development. …”
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Safety and efficacy of long-term nicotinamide mononucleotide supplementation on metabolism, sleep, and nicotinamide adenine dinucleotide biosynthesis in healthy, middle-aged Japane... by Shintaro Yamaguchi, Junichiro Irie, Masanori Mitsuishi, Yuichi Uchino, Hideaki Nakaya, Ryo Takemura, Emi Inagaki, Shotaro Kosugi, Hideyuki Okano, Masato Yasui, Kazuo Tsubota, Kaori Hayashi, Jun Yoshino, Hiroshi Itoh

“…Accumulating evidence from both rodents and humans suggests that the levels of nicotinamide adenine dinucleotide (NAD+), a regulator of many biological processes, declines in multiple organs and tissues with aging and obesity. …”
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A Multiagent Alphavirus DNA Vaccine Delivered by Intramuscular Electroporation Elicits Robust and Durable Virus-Specific Immune Responses in Mice and Rabbits and Completely Protect... by Lesley C. Dupuy, Michelle J. Richards, Brian D. Livingston, Drew Hannaman, Connie S. Schmaljohn

“…There remains a need for vaccines that can safely and effectively protect against the biological threat agents Venezuelan (VEEV), western (WEEV), and eastern (EEEV) equine encephalitis virus. …”
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Deoxycholic Acid as a Modifier of the Permeation of Gliclazide through the Blood Brain Barrier of a Rat by Mladena Lalić-Popović, Velibor Vasović, Boris Milijašević, Svetlana Goločorbin-Kon, Hani Al-Salami, Momir Mikov

“…Bile acids are known for their hypoglycemic effect and as promoters of drug penetration across biological membranes. Accordingly, the aim of this study is to investigate whether the bile acid (deoxycholic acid) can change the permeation of gliclazide, through the blood brain barrier of a rat model type-1 diabetes. …”
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Tirosin Kinase Inhibitors in Chronic Graft versus Host Disease: From Bench to Bedside by Jacopo Olivieri, Sabrina Coluzzi, Imma Attolico, Attilio Olivieri

“…While the exact mechanisms leading to such efficacy are still under investigation, use of TKIs in the context of clinical trials should be promoted, aiming to evaluate the biological changes induced in vivo by TKIs and to assess the long term outcome of these patients. …”
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Varying effects of Vicia sativa and Vicia villosa on bacterial composition and enzyme activities in nutrient-deficient sugarcane soils under greenhouse conditions by Emihle Ngonini, María A. Pérez-Fernández, Anathi Magadlela

“…A greenhouse experiment was conducted to evaluate the chemical and biological inputs of V. sativa and V. villosa in nutrient-deficient, KwaZulu-Natal (KZN) sugarcane plantation soils. …”
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Genetic Vectors as a Tool in Association Studies: Definitions and Application for Study of Rheumatoid Arthritis by Igor Sandalov, Leonid Padyukov

“…This consolidation of genotypes into GVs provides integration of multiple genetic variants for a single statistical test and excludes ambiguity of biological interpretation known for allele and haplotype associations. …”
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Paget’s disease of the breast: a contemporary perspective by O. O. Yemelyanova, A. D. Zikiryakhodzhaev, N. N. Volchenko, V. V. Efanov

“…It is possible to improve survival statistics by analyzing the biological characteristics of the tumor and developing a more accurate approach to the treatment of patients in this category. …”
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HEAVY METALS IN SURFACE SEAWATER AND SEDIMENT FROM THE COAST OF KHANH HOA PROVINCE: LEVELS AND ECOLOGICAL RISK ASSESSMENT by Xuan Thuy Nguyen, Nhat Nhu Thuy Nguyen, Hung Phu Le, Trong Dung Le, Viet Ha Dao, Xuan Vy Nguyen

“…Ecological risk assessment of the sediments also indicated a possible combined biological effect of Cu, Pb, and Zn at Cam Ranh. Therefore, heavy metals in the marine environment at Khanh Hoa should be monitored yearly. …”
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Sliding Dynamics of a Filippov Forest-Pest Model with Threshold Policy Control by Lirong Liu, Changcheng Xiang, Guangyao Tang, Yuan Fu

“…More importantly, four cases of sliding bifurcations of the Filippov system with respect to different types of equilibria of subsystems are investigated, and the corresponding biological implications concerning integrated pest management (IPM) are analyzed. …”
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Geomodeling soil quality using remote sensing and land use metrics in Abeokuta, Nigeria by Tobore Anthony, Anoke Emmanuel

“…A composite of 70 soil samples (0 to 30 cm) were analyzed for their physical, chemical, and biological soil properties. The additive, weighted-additive, and proposed models were used to estimate SQ of the studied area. …”
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Comparative Molecular Field Analysis (CoMFA) for Thiotetrazole Alkynylacetanilides, a Non-Nucleoside Inhibitor of HIV-1 Double Mutant K103N/Y181C Reverse Transcriptase by Sivan Sree Kanth, Kotla Sai Abhishake, Manga Vijjulatha

“…The CoMFA model provided the most significant correlation of steric and electrostatic fields with biological activities. The information rendered by 3D QSAR model may afford valuable clues to optimize the lead and design new potential inhibitors…”
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The ACE2/Apelin Signaling, MicroRNAs, and Hypertension by Lai-Jiang Chen, Ran Xu, Hui-Min Yu, Qing Chang, Jiu-Chang Zhong

“…This paper focuses on what is known about the ACE2/Apelin signaling and its biological roles, paying particular attention to interactions and crosstalk among the ACE2/Apelin signaling, microRNAs, and hypertension, aiming to facilitate the exploitation of new therapeutic medicine to control hypertension.…”
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Isolation and Characterization of Plant Growth-Promoting Rhizobacteria from Coffee Plantation Soils and Its Influence on Maize Growth by Yasin Ahmed Waday, Ermias Girma Aklilu, Mohammed Seid Bultum, Venkata Ramayya Ancha, Dejene Beyene

“…The results indicate that the JEC4 isolate can be developed as a biological fertilizer for promoting crop productivity and ecosystem dynamics.…”
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Antifungal and Antibacterial Activity of Aqueous and Ethanolic Extracts of Different <i>Rosa rugosa</i> Parts by Žaneta Maželienė, Jolita Kirvaitienė, Kamilė Kaklauskienė, Rasa Volskienė, Asta Aleksandravičienė

“…With the rising incidence of drug-resistant pathogens, focus should be placed on biologically active compounds derived from plant species used in herbal medicine, as these compounds may provide a new source of antifungal and antibacterial activities. …”
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