A Novel Mathematical Approach to Define the Genes/SNPs Conferring Risk or Protection in Sporadic Amyotrophic Lateral Sclerosis Based on Auto Contractive Map Neural Networks and Gra... by Massimo Buscema, Silvana Penco, Enzo Grossi

“…On the other hand ADRB3, LIPC, and MMP3, whose hub relevancies contribution resulted to be as high as 0.13, seem to represent susceptibility factors. Conclusion. The biological information available on these six polymorphisms is consistent with possible pathogenetic pathways related to ALS.…”
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DPSCs Protect Architectural Integrity and Alleviate Intervertebral Disc Degeneration by Regulating Nucleus Pulposus Immune Status by Xiwen Dong, Fanqi Hu, Jing Yi, Yuning Zhang, Chao Liu, Panpan Geng, Han Duan, Chu-Tse Wu, Xuesong Zhang, Hua Wang

“…Few effective therapeutic strategies are available for IVD degeneration treatment. To understand the biological effects of dental pulp stem cells (DPSCs) on nucleus pulposus (NP) cells, we carried out RNA sequencing, bioinformatic analysis which unveiled gene expression differences, and pathway variation in primarily isolated patients’ NP cells after treatment with DPSCs supernatant. …”
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Allograft Cellular Bone Matrix in Extreme Lateral Interbody Fusion: Preliminary Radiographic and Clinical Outcomes by Antoine G. Tohmeh, Blake Watson, Mirna Tohmeh, Xavier J. Zielinski

“…The clinical use of allograft cellular bone graft has potential advantages over autograft by eliminating the need to harvest autograft while mimicking autograft's biologic function. The objective of this study was to examine 12-month radiographic and clinical outcomes in patients who underwent XLIF with Osteocel Plus, one such allograft cellular bone matrix. …”
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Nuclear Magnetic Resonance Fingerprinting and Principal Component Analysis Strategies Lead to Anti-Tuberculosis Natural Product Discovery from Actinomycetes by Jianying Han, Xueting Liu, Lixin Zhang, Ronald J. Quinn, Miaomiao Liu

“…Notable findings include borrelidin, a potent threonyl-tRNA synthetase inhibitor with broad biological activities, and L-O-Lac-L-Val-D-O-Hiv-D-Val, a peptide isolated for the first time from a plant endophyte, demonstrating broad-spectrum antimicrobial activity. …”
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A systematic review on the impact of breastfeeding on cancer risk, weight loss, cardiovascular disease, type 2 diabetes mellitus in mothers, and the role of fathers, medical person... by Olga Krupa, Daria Rybak, Katarzyna Kamińska-Omasta, Bartosz Omasta, Kuba Borys Romańczuk, Magdalena Agata Czerska, Paulina Dorota Pietrukaniec, Szymon Przemysław Stolarczyk, Zofia Martyna Wójcik, Kinga Furtak

“…The available data allow us to conclude that breastfeeding is an effective preventive health strategy, but further research is needed to understand the biological mechanisms and identify optimal supportive interventions. …”
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Study of water quality in ex-mining pits for fish cultivation in Gunung Mas regency, Central Kalimantan by Lukas Inel, Infa Minggawati, Tania Serezova Augusta, Frid Agustinus, Fenky Wirada

“…The results show that the water quality for both mine pits with water parameters for: dissolved oxygen (DO) on average 6.09 mg/l – 7.45 mg/l, pH 2.94 – 3.54, Biological Oxygen Demand (BOD) 4.78 mg/L, temperature 30 -32 oC, turbidity 51.7-53.5 NTU, value of Total Dissolved Solids (TDS) 0.003 – 0.017 gr/L, mercury (Hg) content of 0.000247 mg/l - 0.000359 mg/l, the depth of the pool is 1.7 m – 2.74 m. …”
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Talent identification and development in judo: A systematic review by Aline Aparecida de Souza Ribeiro, Francisco Zacaron Werneck, João Guilherme Vieira, Leandro Sant’Ana, Kathryn Johnston, Joseph Baker, Jeferson Macedo Vianna

“…Few studies examined female samples, psychological skills or biological maturation. Only 20% of the studies used multivariate analyses. …”
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Protein Identification Improvement in Complex Samples Using Higher Frequency MS Acquisition and PEAKS Software by Arman Kulyyassov, Saya Makhsatova, Aruzhan Kurmanbay

“…Protein identification in complex biological samples using the shotgun mode of LC-MS/MS is typically enhanced by employing longer LC columns and extended gradient times. …”
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Transitions in intensive care: Investigating critical slowing down post extubation. by Lucinda Khalil, Sandip V George, Katherine L Brown, Samiran Ray, Simon Arridge

“…Complex biological systems undergo sudden transitions in their state, which are often preceded by a critical slowing down of dynamics. …”
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Multimodal neural correlates of childhood psychopathology by Jessica Royer, Valeria Kebets, Camille Piguet, Jianzhong Chen, Leon Qi Rong Ooi, Matthias Kirschner, Vanessa Siffredi, Bratislav Misic, BT Thomas Yeo, Boris C Bernhardt

“…Our findings help in better understanding biological mechanisms underpinning dimensions of psychopathology, and could provide brain-based vulnerability markers.…”
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The inflammatory profiling in a cohort of older patients suffering from cognitive decline and dementia by Beatrice Arosio, Paolo Dionigi Rossi, Evelyn Ferri, Ernesto Consorti, Simona Ciccone, Tiziano Angelo Lucchi, Nicola Montano

“…Frailty represents a condition of increased vulnerability to stresses and reduced homeostatic reserve reflecting not only health status but also biological age. In older subjects without dementia, we showed that markers of inflammaging were differently associated with chronological age than with frailty. …”
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Coupling between topological edge state and defect mode-based biosensor using phononic crystal by Zaky A. Zaky, M. Al-Dossari, Ahmed S. Hendy, Yassine Bouazzi, Attia Boudjemline, Arafa H. Aly

“…Besides, the salinity of seawater is a crucial factor in understanding its characteristics because any variation in the salinity of seawater represents the variations in the hydrological, biological, and chemical distributions. In this paper, a symmetrical one-dimensional phononic structure is theoretically designed using two symmetrical crystals separated with a defective cavity. …”
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Differentially expressed whey proteins of donkey and bovine colostrum revealed with a label-free proteomics approach by Mohan Li, Qilong Li, Haikun Yu, Xiumin Zhang, Dehao Li, Wanying Song, Yan Zheng, Xiqing Yue

“…Gene Ontology analysis revealed that these DEWPs were mainly related to cellular components, such as extracellular exosome, plasma membrane, and mitochondrion; biological processes, such as oxidation-reduction process, cell-cell adhesion, and small guanosine triphosphate (GTP) ase-mediated signal transduction; and molecular functions, such as GTP binding, GTPase activity, and soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein receptor activity. …”
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Symptom Status Predicts Patient Outcomes in Persons with HIV and Comorbid Liver Disease by Wendy A. Henderson, Angela C. Martino, Noriko Kitamura, Kevin H. Kim, Judith A. Erlen

“…The model components include biological/physiological factors (HIV viral load, CD4 counts), symptom status (Beck Depression Inventory II and the Medical Outcomes Study HIV Health Survey (MOS-HIV) mental function), functional status (missed appointments and MOS-HIV physical function), general health perceptions (perceived burden visual analogue scale and MOS-HIV health transition), and overall quality of life (QOL) (Satisfaction with Life Scale and MOS-HIV overall QOL). …”
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Rapid Acquisition of High-Pixel Fluorescence Lifetime Images of Living Cells via Image Reconstruction Based on Edge-Preserving Interpolation by Yinru Zhu, Yong Guo, Xinwei Gao, Qinglin Chen, Yingying Chen, Ruijie Xiang, Baichang Lin, Luwei Wang, Yuan Lu, Wei Yan

“…Fluorescence lifetime imaging (FLIM) has established itself as a pivotal tool for investigating biological processes within living cells. However, the extensive imaging duration necessary to accumulate sufficient photons for accurate fluorescence lifetime calculations poses a significant obstacle to achieving high-resolution monitoring of cellular dynamics. …”
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Probabilistic genotype-phenotype maps reveal mutational robustness of RNA folding, spin glasses, and quantum circuits by Anna Sappington, Vaibhav Mohanty

“…Here we introduce probabilistic genotype-phenotype (PrGP) maps, where each genotype maps to a vector of phenotype probabilities, as a more realistic and universal language for investigating robustness in a variety of physical, biological, and computational systems. We study three model systems to show that PrGP maps offer a generalized framework which can handle uncertainty emerging from various physical sources: (1) thermal fluctuation in RNA folding, (2) external field disorder in the spin-glass ground state search problem, and (3) superposition and entanglement in quantum circuits, which are realized experimentally on IBM quantum computers. …”
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Variational graph autoencoder for reconstructed transcriptomic data associated with NLRP3 mediated pyroptosis in periodontitis by Pradeep K. Yadalam, Prabhu Manickam Natarajan, Carlos M. Ardila

“…This method identifies natural groupings within biological data without prior labels. VGAE, a deep learning model, captures complex graph relationships for tasks like link prediction and edge detection. …”
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Nanocomposites for Prosthetic Dental Technology: A Systemic Review by Wafaa Atallah, Nihad AlFuraiji, Oday H Hussein

“…It was previously used primarily in the areas of substance chemical productions and physics; however this has changed through the advancement of new technologies. Over time, biological scientists became aware of its numerous benefits and investigated them in their respective fields. …”
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TGFβ1-Induced Differentiation of Human Bone Marrow-Derived MSCs Is Mediated by Changes to the Actin Cytoskeleton by Mona Elsafadi, Muthurangan Manikandan, Sami Almalki, Mohammad Mobarak, Muhammad Atteya, Zafar Iqbal, Jamil Amjad Hashmi, Sameerah Shaheen, Nehad Alajez, Musaad Alfayez, Moustapha Kassem, Raed Abu Dawud, Amer Mahmood

“…TGFβ is a potent regulator of several biological functions in many cell types, but its role in the differentiation of human bone marrow-derived skeletal stem cells (hMSCs) is currently poorly understood. …”
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Anaesthesia affects immune function and impact on long-term cancer prognosis: A review by Kisdyanti Yuniar Melissa, Suandika Made, Rahmawati Arni Nur

“…The study population is cancer patients, and the research reviewed provides an overview of research into the biological pathways involved, the effects of immunosuppression associated with anaesthesia, and the potential for anaesthetic interventions to minimize the negative impact on cancer prognosis. …”
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