Tributyrin Supplementation Protects Immune Responses and Vasculature and Reduces Oxidative Stress in the Proximal Colon of Mice Exposed to Chronic-Binge Ethanol Feeding by B. Glueck, Y. Han, G. A. M. Cresci

“…The gut microbiota ferments undigested dietary polysaccharides to yield short-chain fatty acids, predominantly acetate, propionate, and butyrate. Butyrate has many biological mechanisms of action including anti-inflammatory and immunoprotective effects, and its depletion is associated with intestinal injury. …”
Get full text

Effect of Liquid Marble 3D Culture System on In Vitro Maturation and Embryo Development of Prepubertal Goat Oocytes by Andrea Podda, Linda Dujíčková, Federica Ariu, Giovanni Giuseppe Leoni, Dolors Izquierdo, Maria-Teresa Paramio, Luisa Bogliolo

“…Three-dimensional (3D) culture systems provide a more biologically appropriate environment compared to traditional two-dimensional (2D) cultures. …”
Get full text

PHILOSOPHIC AND CLINICAL DISCOURSE OF THE TWENTIETH CENTURY by V. M. Skyrtach, R. S. Martynov, A. O. Karpenko

“…Conclusions of the study are summarized in the following positions: the current clinical discourse is based on the positivist-biological trend in humanitarian knowledge and it is the basis for the production and reproduction of medical and pharmaceutical repressive ideology; criticism of philosophical clinical discourse opens the possibility of overcoming the dominance of purely clinicist discourse; such a transformation is possible only after a paradigm shift in understanding the category of subject.…”
Get full text

Biotransformation of Daidzein, Genistein, and Naringenin by Streptomyces Species Isolated from High-Altitude Soil of Nepal by Lasata Shrestha, Bishnu P. Marasini, Suman Prakash Pradhan, Rajib Kumar Shrestha, Suraj Shrestha, Kamal Prasad Regmi, Bishnu Prasad Pandey

“…Furthermore, modification of these naturally occurring flavonoids to structurally diverse compounds through whole cell biotransformation with enhanced biological activities has numerous biotechnological applications. …”
Get full text

Role of physical activity in cardiovascular disease prevention: impact of epigenetic modifications by Yi Sun, Zuoying Peng, Hua Liang

“…Exercise is a potent epigenetic modulator that induces direct and long-lasting genetic changes and activates biological signals associated with cardiovascular health. …”
Get full text

Lepidium sativum Seed Extract-Mediated Synthesis of Zinc Oxide Nanoparticles: Structural, Morphological, Optical, Hemolysis, and Antibacterial Studies by Adnan Alnehia, Annas Al-Sharabi, Abdel-Basit Al-Odayni, A. H. Al-Hammadi, Fares H. AL-Ostoot, Waseem Sharaf Saeed, Naaser A. Y. Abduh, Ali Alrahlah

“…Nanomaterials have unique physicochemical properties compared to their bulk counterparts. Besides, biologically synthesized nanoparticles (NPs) have proven superior to other methods. …”
Get full text

Biodegradation Potential of Oil-based Drill Cuttings Encapsulated with Cement in the Soil Environment by Rim-Rukeh Akpofure

“…Results of soil analyses show that physico-chemical and biological characteristics of the soil environment as; pH (5.6 – 3.9), temperature (27.7 – 39.5 oC), redox potential (-114mV – (-80mV), total organic carbon (12.7% - 7.3%), sulphate (0.7 – 0.2mg/l), nitrate (6.7 – 2.2mg/l), moisture content (82-89%) and total microbial count (105 – 1013 cfu/g). …”
Get full text

Comprehensive assessment of a miRNA-mRNA regulatory network in Meretrix meretrix: Implications for metabolism and autophagy across divergent growth rates by Yuchen Wang, Zhidong Zhang, Suhua Chen, Yangping Wu, Qiujie Li, Yi Cao, Yu Zhang, Aihua Chen

“…Characterized by their dynamic expression patterns, miRNAs play a crucial role in regulating a multitude of biological processes, including metabolism and autophagy. …”
Get full text

Soft Sensor Modeling Method Based on SPA-GWO-SVR for Marine Protease Fermentation Process by Zhu Li, Khalil Ur Rehman, Liu Wenhui, Faiza Atique

“…Finally, the Excel spreadsheet data was called by MATLAB programming, and the established SPA-GWO-SVR soft sensor model predicted crucial biological variables. The simulation results show that the SPA-GWO-SVR model has higher prediction accuracy and generalization ability than the traditional SPA-SVR model. …”
Get full text

ASPM Promotes the Progression of Anaplastic Thyroid Carcinomas by Regulating the Wnt/β-Catenin Signaling Pathway by Liang Jiang, Shuai Zhang, Ning An, Guoqing Chai, Changhong Ye

“…Wnt/β-catenin signaling was suppressed in response to ASPM inhibition, while rescue of β-catenin expression restored the impaired biological functions of ATC cells. In vivo transplantation of ASPM-knockdown cells inhibited the growth of tumors. …”
Get full text

Directions for Reducing Pesticide Pressure on Agro-Landscapes by Hadzalo Yaroslav, Likar Yaroslav, Beknozarova Zamira

“…For example, the hybrid Yason demonstrated an increase in this indicator by 15.2% due to the use of the Agat-25K biological protection method. Furthermore, Agat-25K contributed to a 4.6% increase in the weight of 1,000 seeds, with the hybrid Yason showing an average weight of 63.5 g, compared to the control (60.7 g). …”
Get full text

Low-temperature biodegradation of freshwater dissolved organic matter during winter-to-spring transition by Corentin Bouvet, Pascale B. Beauregard, Céline Guéguen

“…The composition of dissolved organic matter (DOM) directly affects the biological degradation processes and its persistence in aquatic systems. …”
Get full text

Transcriptome-Based Modeling Reveals that Oxidative Stress Induces Modulation of the AtfA-Dependent Signaling Networks in Aspergillus nidulans by Erzsébet Orosz, Károly Antal, Zoltán Gazdag, Zsuzsa Szabó, Kap-Hoon Han, Jae-Hyuk Yu, István Pócsi, Tamás Emri

“…To elucidate the potential global regulatory role of AtfA governing expression of a high number of genes with very versatile biological functions, we devised a model based on the comprehensive transcriptomic data. …”
Get full text

Serum Analysis in Patients with Temporomandibular Disorders: A Controlled Cross-Sectional Study in Norway by Kordian Staniszewski, Henning Lygre, Trond Berge, Annika Rosén

“…However, most of the TMD patients and controls had values within normal biological range. Our findings could not associate any severe systemic disease, malnutrition, or systemic inflammation with the TMD. …”
Get full text

Practical Recommendations of Scientific Society for the Study of Human Microbiome and Russian Gastroenterological Association (RGA) for Probiotics in Treatment and Prevention of Ga... by V. T. Ivashkin, I. V. Mayev, D. I. Abdulganieva, S. A. Alekseenko, N. Yu. Ivashkina, N. V. Korochanskaya, S. N. Mammaev, E. A. Poluektova, A. S. Trukhmanov, Yu. P. Uspensky, V. V. Tsukanov, O. S. Shifrin, O. Yu. Zolnikova, K. V. Ivashkin, T. L. Lapina, R. V. Maslennikov, A. I. Ulyanin

“…Probiotics can be registered in the Russian Federation as biologically active food additives (BAFA) or as pharmaceutical products (drugs) in accordance with the microbiological standards and legislative requirements of the Russian Federation. …”
Get full text

Accelerated dynamic light sheet microscopy: unifying time-varying patterned illumination and low-rank and sparsity constrained reconstruction by Marco Tobia Vitali, Alessia Candeo, Andrea Farina, Paolo Pozzi, Alessia Brix, Andrea Bassi, Teresa M Correia

“…Our approach represents a step forward in enhancing the temporal resolution of LSFM for studying fast biological dynamics.…”
Get full text

Multivariate modeling of the Fenton process for enhanced COD removal and low sludge generation in landfill leachate treatment by Nader Biglarijoo, Amin Shams

“…Biological treatment methods are not practical when it comes to landfill leachate treatment. …”
Get full text

Nonviral targeted mRNA delivery: principles, progresses, and challenges by Xi He, Guohong Li, Letao Huang, Haixing Shi, Sha Zhong, Siyu Zhao, Xiangyu Jiao, Jinxiu Xin, Xiaoling Yin, Shengbin Liu, Zhongshan He, Mengran Guo, Chunli Yang, Zhaohui Jin, Jun Guo, Xiangrong Song

“…However, the deficiency in transfection efficiency and targeted biological distribution are still the major challenges for the mRNA delivery systems. …”
Get full text

Practical Recommendations of Scientific Society for the Study of Human Microbiome and the Russian Gastroenterological Association on Use of Probiotics, Prebiotics, Synbiotics and F... by V. T. Ivashkin, I. V. Maev, D. I. Abdulganieva, S. A. Alekseenko, A. V. Gorelov, I. N. Zakharova, O. Yu. Zolnikova, N. Yu. Ivashkina, N. V. Korochanskaya, S. N. Mammayev, E. A. Poluektova, A. S. Trukhmanov, D. V. Usenko, Yu. P. Uspensky, V. V. Tsukanov, O. S. Shifrin, I. V. Berezhnaya, K. V. Ivashkin, T. L. Lapina, R. V. Maslennikov, S. V. Nikolaeva, N. G. Sugyan, A. I. Ulyanin

“…The mechanism of probiotic action comprises the quorum resistance maintenance, nutrient substrate metabolism and end metabolite recycling, macroorganism-sustaining substrate production, as well as the mediation of local and adaptive immune responses.The Russian Federation regulates market differently for biologically active food additives (BAFA), medicinal products (drugs) and functional food products (FFP). …”
Get full text

A Review on Expression, Pathological Roles, and Inhibition of TMPRSS2, the Serine Protease Responsible for SARS-CoV-2 Spike Protein Activation by Jyotirmoy Sarker, Pritha Das, Sabarni Sarker, Apurba Kumar Roy, A. Z. M. Ruhul Momen

“…Complete understanding of the biological roles of TMPRSS2 is necessary before such therapies are applied.…”
Get full text