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15641
Harnessing Genetic Resistance in Maize and Integrated Rust Management Strategies to Combat Southern Corn Rust
Published 2025-01-01“…This review gives a concise overview of the biological characteristics and symptoms of SCR, its life cycle, the molecular basis of interactions between maize and <i>P. polysora</i>, the genetic resistance of maize to SCR, the network of maize resistance to <i>P. polysora</i> infection, SCR management, and future perspectives.…”
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15642
miR-370-3p as a Novel Biomarker Promotes Breast Cancer Progression by Targeting FBLN5
Published 2021-01-01“…miRNAs play a crucial part in multiple biological processes of cell proliferation, migration, apoptosis, and chemoresistance. …”
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15643
Downregulation of HBx Restrains Proliferation, Migration, and Invasion of HepG2 Cells
Published 2021-01-01“…Results of CCK-8, Transwell, wound healing, and colony formation assays suggested that HBx could mediate biological function of HepG2 cells by activating the XB130-mediated PI3K/AKT pathway. …”
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15644
Evaluation of hesperidin as a potential larvicide against Culex pipiens with computational prediction of its mode of action via molecular docking
Published 2025-01-01“…Abstract Hesperidin, a natural flavanone glycoside predominantly found in citrus fruits, has gained attention for its wide-ranging biological activities, including potential insecticidal properties. …”
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15645
Peroxiredoxin 6 Attenuates Alloxan-Induced Type 1 Diabetes Mellitus in Mice and Cytokine-Induced Cytotoxicity in RIN-m5F Beta Cells
Published 2020-01-01“…We hypothesised that PRDX6, which is well known for its various biological functions, including antioxidant activity, may provide an antidiabetic effect. …”
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15646
Controversies in the management of anti-TNF therapy in patients with Crohn’s disease: a Delphi consensus
Published 2024-01-01“…These statements cover: (1) use of first-line non-anti-TNF biological therapy; (2) role of HLA-DQA1*05 in daily practice; (3) attitudes in primary non-response and loss of response to anti-TNF therapy due to immunogenicity; (4) use of ustekinumab or vedolizumab if a change in action mechanism is warranted; (5) anti-TNF drug level monitoring; (6) combined therapy with an immunomodulator.Conclusion This document sought to pull together the best evidence, experts’ opinions, and treating physicians’ attitudes when using anti-TNF therapies in patients with CD.…”
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15647
METTL3 regulates autophagy of hypoxia-induced cardiomyocytes by targeting ATG7
Published 2025-02-01“…Abstract N6-methyladenosine (m6A) mRNA modification is the most common mRNA internal modification in eukaryotes, which participates in a variety of biological processes. However, the role of m6A methylation in regulating autophagy induced by ischemia and hypoxia remains to be widely investigated. …”
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15648
Bioenergy agroecosystems as a basis for food sustainability
Published 2025-01-01“…The application of biological crop protection systems and energy self-sufficiency reduces production costs by 30%, while the quality and market value of high-end food products increase accordingly. …”
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15649
Transcriptome Concordance Between Borderline Tumors and Endometrioid Carcinoma: An Integrative Genomic Analysis
Published 2025-01-01“…Furthermore, the transcriptomic data highlighted a novel and substantial similarity between BOTs and EC, suggesting deeper biological linkages, including potentially shared oncogenic pathways or tumor microenvironmental factors. …”
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15650
Circulating miRNA-125b Is a Potential Biomarker Predicting Response to Rituximab in Rheumatoid Arthritis
Published 2014-01-01“…Although biologic therapies have changed the course of rheumatoid arthritis (RA), today’s major challenge remains to identify biomarkers to target treatments to selected patient groups. …”
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15651
Kemampuan Predasi Ikan Kepala Timah Aplocheilus panchax Jantan dan Betina Terhadap Larva Nyamuk Aedes aegypti
Published 2021-02-01“…Pemanfaatan ikan kepala timah (Aplocheilus panchax / A. panchax) sebagai pengendali vektor secara biologis bertujuan untuk memutus rantai penularan. …”
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15652
Silymarin: a promising modulator of apoptosis and survival signaling in cancer
Published 2025-01-01“…Abstract Cancer, one of the deadliest diseases, has remained the epicenter of biological research for more than seven decades. Yet all the efforts for a perfect therapeutic cure come with certain limitations. …”
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15653
Role of aquaporins in brain water transport and edema
Published 2025-01-01“…Water serves as the primary substance in all living cells and is an essential molecule involved in numerous biological processes critical for maintaining homeostasis in the central nervous system (CNS). …”
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15654
Responsive nanomaterials in biomedicine, patent path and prospect analysis
Published 2025-02-01“…Each developmental phase has increasingly focused on adapting to complex biological environments, achieving superior targeting performance, and enhancing therapeutic efficacy. …”
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15655
Synthesis, Characterization, and Antibacterial Activities of 1H-Imidazo [5, 6-f] [1,10] Phenanthroline-2(3H)-Thione and Its Ni(II) and Cu(II) Complexes
Published 2019-01-01“…Heterocycles are known by their broad spectrum of biological activities, so a search for a new drug from heterocycles can elevate the chance of success. …”
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15656
Quinoline-Based Materials: Spectroscopic Investigations as well as DFT and TD-DFT Calculations
Published 2022-01-01“…Quinoline derivatives such as 15,15-difluoro-[1,3,2] diaazaborininodiquinoline (DDP) and 15,15-difluoro-[1,3,2] diaazaborininodiquinoline acetonitrile (DDPA) have a range of biological and medical activities. So, it is vital to shed light on these compounds in terms of their optical properties supported by quantum calculations. …”
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15657
Anti-TNF-Alpha-Adalimumab Therapy Had Time Lag of Improvement in Synovial Hypertrophy Compared to Rapid Response in Power Doppler Synovial Vascularity
Published 2017-01-01“…The time needed for synovial hypertrophy to decrease may be up to 3–6 months after adalimumab therapy. Switching to biological therapy before 3–6 months is inappropriate and ineffective.…”
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15658
Microclonal propagation of elite industrial grape cultivars (<i>Vitis vinifera</i> L.)
Published 2024-01-01“…The grape is one of the most economically significant berry crops: its cultivation area covers over 6.7 million hectares. Due to certain biological characteristics of grapes, such as a long juvenile period (5–8 years), a high degree of genomic heterozygosity, and the frequently encountered phenomenon of inbred depression, when homozygotization during hybridization leads to a loss of viability and production characteristics of the cultivar, vegetative propagation becomes the basis for grape reproduction and industrial cultivation. …”
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15659
Angel in “the Cartesian theatre” – Aquinas and the mind-body problem
Published 2018-10-01“…Such approach was even called biological, because of the stress on the role which body plays in human actions. …”
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15660
Early Healing Events around Titanium Implant Devices with Different Surface Microtopography: A Pilot Study in an In Vivo Rabbit Model
Published 2012-01-01“…Because of these implant shape and placement site, the device gained a firm mechanical stability but the largest portion of the implant surface lacked direct contact with host bone and faced a wide peri-implant space rich in marrow tissue, intentionally created in order to study the interfacial interaction between metal surface and biological microenvironment. The insertion of titanium devices into the proximal tibia elicited a sequence of healing events. …”
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