Intravenous Laser Blood Irradiation and Tocilizumab in a Patient with Juvenile Arthritis by Dragos Andrei Chiran, Michael Weber, Laura Marinela Ailioaie, Eovelina Moraru, Constantin Ailioaie, Daniela Litscher, Gerhard Litscher

“…This study presents effects of intravenous laser blood irradiation (ILBI) in a transient immunodeficiency patient with juvenile idiopathic arthritis (JIA) treated with an interleukin-6 receptor inhibitor (Tocilizumab). Biological agents induce JIA remission, but some patients do not respond favorably to this final therapeutic line of defense. …”
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Crosstalk between MicroRNAs and Peroxisome Proliferator-Activated Receptors and Their Emerging Regulatory Roles in Cardiovascular Pathophysiology by Yin-Feng Zhang, Hai-Ming Xu, Fei Yu, Man Wang, Meng-Yang Li, Tao Xu, Yan-Yan Gao, Jian-Xun Wang, Pei-Feng Li

“…This provides an understanding of the underlying mechanism of the biological process related to CVD pathophysiology involving the interaction of PPARs and miRNAs and will lead to the development of PPARs/miRNAs as effective anti-CVD medications.…”
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Comparison of characteristics and immune responses between paired human nasal and bronchial epithelial organoids by Lu Zhu, Wenhao Yang, Jiaxin Luo, Danli Lu, Yanan Hu, Rui Zhang, Yan Li, Li Qiu, Zelian Chen, Lina Chen, Hanmin Liu

“…Conclusions NO and BO serve as robust in vitro models, faithfully recapitulating the biological characteristics of upper respiratory epithelial cells. …”
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Multi-material and multi-scale platform for robotic based in situ bioprinting by Andrea Guerra, Gabriele Maria Fortunato, Elisa Batoni, Giovanni Vozzi, Carmelo De Maria

“…IMAGObot was able to successfully reconstruct the skull defect by autonomously alternating different bioprinting technologies and light curing of the deposited biomaterial, thus recapitulating different features of the damaged biological tissue.…”
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Gene Structures, Classification, and Expression Models of the DREB Transcription Factor Subfamily in Populus trichocarpa by Yunlin Chen, Jingli Yang, Zhanchao Wang, Haizhen Zhang, Xuliang Mao, Chenghao Li

“…Taken together, these observations may lay the foundation for future functional analyses to unravel the biological roles of Populus’ DREB genes.…”
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An Open-source Python Tool for Traction Force Microscopy on Micropatterned Substrates by Artur Ruppel, Vladimir Misiak, Martial Balland

“…Cell-generated forces play a critical role in driving and regulating complex biological processes, such as cell migration and division and cell and tissue morphogenesis in development and disease. …”
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Thyroid-Specific Genes Expression Uncovered Age-Related Differences in Pediatric Thyroid Carcinomas by Maria Isabel Cunha Vieira Cordioli, Lais Moraes, Maria Teresa de Seixas Alves, Rosana Delcelo, Osmar Monte, Carlos Alberto Longui, Adriano Namo Cury, Janete Maria Cerutti

“…Our data suggest that biological behaviors of DTC in adolescents might differ from those in children and adults. …”
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An in vitro model of the glomerular capillary wall using electrospun collagen nanofibres in a bioartificial composite basement membrane. by Sadie C Slater, Vince Beachley, Thomas Hayes, Daming Zhang, Gavin I Welsh, Moin A Saleem, Peter W Mathieson, Xuejun Wen, Bo Su, Simon C Satchell

“…The filtering unit of the kidney, the glomerulus, contains capillaries whose walls function as a biological sieve, the glomerular filtration barrier. …”
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S‐PLM: Structure‐Aware Protein Language Model via Contrastive Learning Between Sequence and Structure by Duolin Wang, Mahdi Pourmirzaei, Usman L. Abbas, Shuai Zeng, Negin Manshour, Farzaneh Esmaili, Biplab Poudel, Yuexu Jiang, Qing Shao, Jin Chen, Dong Xu

“…Abstract Proteins play an essential role in various biological and engineering processes. Large protein language models (PLMs) present excellent potential to reshape protein research by accelerating the determination of protein functions and the design of proteins with the desired functions. …”
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The Role of AChE in Swimming Behavior of Daphnia magna: Correlation Analysis of Both Parameters Affected by Deltamethrin and Methomyl Exposure by Qing Ren, Ruibin Zhao, Cheng Wang, Shangge Li, Tingting Zhang, Zongming Ren, Meiyi Yang, Hongwei Pan, Shiguo Xu, Jianping Zhu, Xun Wang

“…The unpredictable toxicity of insecticides may cause behavior disorder of biological organisms. In order to assess the role of acetylcholinesterase (AChE) in swimming behavior of Daphnia magna, a correlation analysis of both parameters in 24 h exposure of deltamethrin (DM) and methomyl (MT) was investigated. …”
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PHARAOH: A collaborative crowdsourcing platform for phenotyping and regional analysis of histology by Kevin Faust, Min Li Chen, Parsa Babaei Zadeh, Dimitrios G. Oreopoulos, Alberto J. Leon, Ameesha Paliwal, Evelyn Rose Kamski-Hennekam, Marly Mikhail, Xianpi Duan, Xianzhao Duan, Mugeng Liu, Narges Ahangari, Raul Cotau, Vincent Francis Castillo, Nikfar Nikzad, Richard J. Sugden, Patrick Murphy, Safiyh S. Aljohani, Philippe Echelard, Susan J. Done, Kiran Jakate, Zaid Saeed Kamil, Yazeed Alwelaie, Mohammed J. Alyousef, Noor Said Alsafwani, Assem Saleh Alrumeh, Rola M. Saleeb, Maxime Richer, Lidiane Vieira Marins, George M. Yousef, Phedias Diamandis

“…Moreover, by using our PHARAOH pipeline, we showcase how correlation of cohort-level cytoarchitectural features with accompanying biological and outcome data can help systematically devise interpretable morphometric models of disease. …”
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Semantic Modeling for SNPs Associated with Ethnic Disparities in HapMap Samples by HyoYoung Kim, Won Gi Yoo, Junhyung Park, Heebal Kim, Byeong-Chul Kang

“…Ethnicity-specific genes were identified as follows: 22 genes in the USA (CEU) individuals, 25 genes in the Japanese (JPT) individuals, and 332 genes in the African (YRI) individuals. To analyze the biologically functional implications for ethnicity-specific SNPs, we focused on constructing a semantic network model. …”
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Quantification of Malondialdehyde in Atmospheric Aerosols: Application of the Thiobarbituric Acid Method by David H. Gonzalez, Suzanne E. Paulson

“…The thiobarbituric acid (TBA) acid assay for MDA has been used as a marker for reactive oxygen species (ROS), oxidative stress, and lipid peroxidation in biological samples for decades. Here we apply the TBA assay to estimate the amount of MDA in ambient fine particulate matter (PM2.5) for the first time, in samples containing biomass burning/urban aerosol from Fresno, CA, and urban aerosol from Los Angeles. …”
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Proteomic Profiling of Ex Vivo Expanded CD34-Positive Haematopoetic Cells Derived from Umbilical Cord Blood by Heiner Falkenberg, Teja Falk Radke, Gesine Kögler, Kai Stühler

“…Enrichment analysis of biological processes clearly showed a proteomic change toward a protein biosynthesis phenotype already within the first three days of expression.…”
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Mechano-gated iontronic piezomemristor for temporal-tactile neuromorphic plasticity by Xiao Wei, Zhixin Wu, Hanfei Gao, Shiqi Cao, Xue Meng, Yuqun Lan, Huixue Su, Zhenglian Qin, Hang Liu, Wenxin Du, Yuchen Wu, Mingjie Liu, Ziguang Zhao

“…However, existing artificial tactile neuromorphic systems struggle to replicate the elaborate temporal plasticity observed between excitatory and inhibitory features in biological systems, which is critical for the biomimetic processing and memorizing of tactile information. …”
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A Simple Visualization Method for Three-Dimensional (3D) Network by Sangkwon Kim, Chaeyoung Lee, Jintae Park, Sungha Yoon, Yongho Choi, Junseok Kim

“…It is used to describe and interpret datasets in various fields such as social network, biological network, and metabolic regulation network. …”
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The Impact of Resource Optimization on the Economic Development of the Marine Industry by Tingting Wang, Xiulian Yang

“…The results show that the final evaluation score of the marine biological industry in Shandong Province is 64.97, which is affected by comprehensive factors. …”
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FGFRL1 Promotes Ovarian Cancer Progression by Crosstalk with Hedgehog Signaling by Haiyan Tai, Zhiyong Wu, Su’an Sun, Zhigang Zhang, Congjian Xu

“…So far, little is known about its biological functions, particularly in cancer development. …”
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Variability in storm season intensity modulates ocean acidification conditions in the northern Strait of Georgia by Wiley Evans, Katie Campbell, Carrie Weekes, Justin Del Bel Belluz, Jessy Barrette, Drew Jordison, Chris Mackenzie, Jonathan Bergshoeff, Carolyn Prentice, Rosie Savage, Isabelle Desmarais, Bryn Fedje, Emma Myers, Kimberly Bedard, Alex Hare, Ian J. W. Giesbrecht, Colleen T. E. Kellogg, Zoe Sandwith, Jennifer M. Jackson

“…These results illustrate that OA is not a “slow burn” process within weakly-buffered settings, but rather invokes periods of intensification with poorly understood biological implications.…”
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Evaluation of different levels of effective microorganism treated teff straw supplementation with concentrate feed on nutrient utilization and performance of yearling local lambs by Abito Asres, Yeshambel Mekuriaw, Likawent Yeheyis

“…Conclusion: Local lambs fed 500 ml effective microorganisms per 1 kg treated teff straw with 350 g of concentrate mixture-based feeding resulted in both biologically efficient and economically profitable. [Vet. …”
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