The Role of Soil Management in Minimizing Water and Nutrient Losses from the Urban Landscape by George Hochmuth, Laurie Trenholm, Esen Momol, Don Rainey, Claire Lewis, Brian Niemann

“… Soil is the most important building block of a healthy, attractive landscape, serving many important physical, chemical, and biological functions. Soil provides a physical substrate for plant support and holds nutrients and water for plant use. …”
Get full text

Cost-effective whole-cell biosynthesis of ursodeoxycholic acid using engineered Escherichia coli with a multienzyme cascade by Xue Zhang, Xue Zhang, Jiagang Xin, Mengyu Liu, Mengyu Liu, Yue Zhang, Yue Zhang, Haoni Luan, Haoni Luan, Wei Feng, Wei Feng, Fei Wang, Fei Wang, Wei Xu, Wei Xu, Peng Song, Peng Song

“…Ursodeoxycholic acid (UDCA) can be used as a drug to treat various liver and bile diseases. Currently, the biological synthesis of UDCA is predominantly conducted via a two-step enzymatic process in which synthesis is catalyzed by 7α-hydroxysteroid dehydrogenase (7α-HSDH) and 7β-hydroxysteroid dehydrogenase (7β-HSDH) in succession, utilizing chenodeoxycholic acid (CDCA) as the substrate. …”
Get full text

Neuroinflammation and ALS: Transcriptomic Insights into Molecular Disease Mechanisms and Therapeutic Targets by Giovanna Morello, Antonio Gianmaria Spampinato, Sebastiano Cavallaro

“…This apparent discrepancy may be due to the absence of an effective stratification of ALS patients into subgroups with markedly different clinical, biological, and molecular features. Our research group recently described genome-wide characterization of motor cortex samples from sporadic ALS (SALS) patients, revealing the existence of molecular and functional heterogeneity in SALS. …”
Get full text

Greenhouse Gases Emissions from Wastewater Treatment Plants: Minimization, Treatment, and Prevention by J. L. Campos, D. Valenzuela-Heredia, A. Pedrouso, A. Val del Río, M. Belmonte, A. Mosquera-Corral

“…The operation of wastewater treatment plants results in direct emissions, from the biological processes, of greenhouse gases (GHG) such as carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O), as well as indirect emissions resulting from energy generation. …”
Get full text

Analysis of Seed Vigor Using the Biospeckle Laser Technique by Roberto A. Braga, José Luís Contado, Karina Renostro Ducatti, Edvaldo A. Amaral da Silva

“…Concerning these limitations, optical-based techniques have emerged as promising alternatives. Among them, the biological laser speckle phenomenon, rooted in optical interferometry, has proven effective in sensitively detecting and monitoring activity levels in living tissues. …”
Get full text

Immunoglobulin Gamma-Like Therapeutic Bispecific Antibody Formats for Tumor Therapy by Shixue Chen, Lingling Li, Fan Zhang, Yu Wang, Yi Hu, Lei Zhao

“…BsAbs with IgG-like architecture exhibit superior advantages in structure (similar to natural antibodies), pharmacokinetics, half-life, FcR-mediated function, and biological activity. This review considers various IgG-like BsAb generation approaches, summarizes the clinical applications of promising new BsAbs, and describes the mechanism of BsAbs in tumor therapy.…”
Get full text

The Le Rozel footprints: snapshots of Neandertal groups in the Late Pleistocene. A combined morphometric and experimental approach by Jérémy Duveau

“…Hominin footprints represent brief moments of life and provide access to the locomotor and biological features of the individuals who left them. …”
Get full text

Citrus Leafminer Parasitoid, Ageniaspis citricola Logvinovskaya (Insecta: Hymenoptera: Encyrtidae) by Alison Walker, Marjorie A. Hoy

“… The encyrtid parasitoid Ageniaspis citricola was first imported into Florida from Australia in 1994 in a classical biological control program against the citrus leafminer, Phyllocnistis citrella Stainton (Hoy and Nguyen 1994a). …”
Get full text

Isolation and Structural Identification of New Diol Esters of Okadaic Acid and Dinophysistoxin-1 from the Cultured <i>Prorocentrum lima</i> by Yeong Kwang Ji, Semin Moon, Sangbum Lee, Yun Na Kim, Eun Ju Jeong, Jung-Rae Rho

“…These results expand our understanding of DSP toxin diversity and provide valuable insight into the structural variations and biological activity of diol esters of OA/DTX-1.…”
Get full text

Field Observations during the Eleventh Microwave Water and Energy Balance Experiment (MicroWEX-11): from April 25, 2012, through December 6, 2012 by Tara Bongiovanni, Pang-Wei Liu, Karthik Nagarajan, Daniel Preston, Patrick Rush, Tim H.M. van Emmerik, Robert Terwilleger, Alejandro Monsivais-Huertero, Jasmeet Judge, Susan Steele-Dunne, Roger De Roo, Ruzbeh Akbar, Ella Baar, Max Wallace, Anthony England

“…This 96-page report was written by Tara Bongiovanni, Pang-Wei Liu, Karthik Nagarajan, Daniel Preston, Patrick Rush, Tim H.M. van Emmerik, Robert Terwilleger, Alejandro Monsivais-Huertero, Jasmeet Judge, Susan Steele-Dunne, Roger De Roo, Ruzbeh Akbar, Ella Baar, Max Wallace, and Anthony England and published by the UF Department of Agricultural and Biological Engineering, July 2015. AE514/AE514: Field Observations during the Eleventh Microwave Water and Energy Balance Experiment (MicroWEX-11): from April 25, 2012, through December 6, 2012 (ufl.edu) …”
Get full text

Determination of FMDV 146S particle concentration by spectrometric method during viral RNA quantification by M. I. Doronin, D. V. Mikhalishin, V. A. Starikov, D. A. Lozovoy, Yu. S. El’kina, A. V. Borisov

“…During FMD vaccine production, special attention is paid to the concentration of 146S particles bearing the critical biological features of FMDV and being the main components that have an effect on vaccine immunogenicity. …”
Get full text

Ecosystem controlling as a solution to complex task of optimizing the technological process of industrial production by I. A. Loskutov, V. G. Iskandarova

“…It is considered from the classical (biological) point of view and from the point of view of application in industry. …”
Get full text

ALKBH5 suppresses gastric cancer tumorigenesis and metastasis by inhibiting the translation of uncapped WRAP53 RNA isoforms in an m6A-dependent manner by Ziqi Zheng, Feizhi Lin, Baiwei Zhao, Guoming Chen, Chengzhi Wei, Xiaojiang Chen, Runcong Nie, Ruopeng Zhang, Zhoukai Zhao, Zhiwei Zhou, Yuanfang Li, Weigang Dai, Yijia Lin, Yongming Chen

“…However, the detailed biological functions and underlying mechanisms of m6A regulation in gastric cancer (GC) are poorly understood. …”
Get full text

Pancreatic Cancer: What the Oncologist Can Offer for Palliation by Malcolm J Moore

“…The effect of combined modality therapy (5-FU with radiotherapy) on survival is unclear, and it does not prevent local disease progression. Some novel biological agents, including angiogenesis inhibitors, matrix metalloproteinase inhibitors, antisense compounds, inhibitors of cell signalling such as epidermal growth factor and vascular endothelial growth factor, and inhibitors of oncogene activation, are undergoing phase II and III trials in patients with pancreatic cancer. …”
Get full text

Composting of municipal solid waste with microbial-inoculated biochar amendment: impact on process and end-product quality by Mohammad Javad Tahsini, Mahnaz Nikaeen, Farzaneh Mohammadi, Ahmadreza Taghipour, Meghdad Tahmasebi, Amir Hossein Nafez

“…The composting process and the quality of the final product were evaluated by analyzing a range of physicochemical and biological parameters. The results demonstrated that piles amended with inoculated biochar exhibited higher levels of FDA hydrolytic activity and organic matter reduction, indicating enhanced microbial activity. …”
Get full text

The Role of TGFβ Signaling in Squamous Cell Cancer: Lessons from Mouse Models by Adam B. Glick

“…Because of these diverse biological processes regulated by TGFβ1, this cytokine and its signaling pathway appear to function at multiple points during carcinogenesis with distinct effects. …”
Get full text

Engineered bacterial membrane biomimetic covalent organic framework as nano-immunopotentiator for cancer immunotherapy by Qi-Chao Yang, Yuan-Yuan Wang, Shuo Wang, An Song, Wen-Da Wang, Liang Zhang, Zhi-Jun Sun

“…The cellular uptake and tissue dispersion efficiency of nanomedicines are crucial for realizing their biological functionality. As a cutting-edge category of nanomedicine, covalent organic frameworks (COFs)-based photosensitizers, have been extensively employed in cancer phototherapy in recent years. …”
Get full text

Application of phytosynthesized silver nanoparticles (SNPs) against Erwinia amylovora causing fire blight disease by Saeed Tarighi, Meysam Soltani Nejad

“…These particles are created through various chemical and biological processes. Numerous studies have demonstrated their ability to exhibit antibacterial properties against a wide range of human and animal pathogens. …”
Get full text

Mechanosynthesis, characterization, and adsorptive properties of Mg–Al-LDH and Zn–Al-LDH for olive mill wastewater treatment by Hosni, Khaled, Mahmoudi, Khaled, Haraketi, Manel, Jellali, Salah, Srasra, Ezzeddine

“…Indeed, after 44 h of contact time, the removed amounts of chemical oxygen demand (COD) and biological oxygen demand (BOD) were assessed at approximately 300 and 100 mg${\cdot }$g$^{-1}$, respectively. …”
Get full text

E3 ubiquitin ligase SYVN1 as a promising therapeutic target for diverse human diseases by Li Zhu, Yong-Ping Liu, Yuan-Wang, Bo-Xuan Sun, Yu-Ting Huang, Ji-Kai Zhao, Jian-Feng Liu, Li-Ming Yu, Hui-Shan Wang

“…SYVN1, an E3 ubiquitin ligase, is characterized by its significant functions in regulating various biological processes, including molecular mechanisms related to gene expression, signaling pathways, and cell death, among others. …”
Get full text