Protective Effect of Acacia nilotica (L.) against Acetaminophen-Induced Hepatocellular Damage in Wistar Rats by Narayanan Kannan, Kunnathur Murugesan Sakthivel, Chandrasekaran Guruvayoorappan

“…The potential biological functions of A. nilotica have long been described in traditional system of medicine. …”
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Quantification of Rhodojaponin II and Rhodojaponin III in Rat Plasma by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry by Cheng Sun, Wanhang Wang, Xi Bao, Dizhong Chen, Shenshen Mei, Jianshe Ma, Xiajuan Jiang

“…These results comply with relevant regulations for drug analysis in biological samples. Therefore, this method is deemed suitable for quantifying Rhodojaponin II and Rhodojaponin III levels in rats.…”
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Cross-Talk between PPARs and the Partners of RXR: A Molecular Perspective by Lap Shu Alan Chan, Richard A. Wells

“…Therefore, the PPARs often complete with other RXR-dependent nuclear receptors and this competition has important biological implications. Thorough understanding of this cross-talk at the molecular level is crucial to determine the detailed functional roles of the PPARs. …”
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Age-structured cell population model to study the influence of growth factors on cell cycle dynamics by Frédérique Billy, Jean Clairambault, Franck Delaunay, Céline Feillet, Natalia Robert

“…Cell proliferation is at its first stages exponential and is thus characterised by its growth exponent, the first eigenvalue of the linear system we consider here, a growth exponent that we will explicitly evaluate from biological data.Moreover, this study relies on recent and innovative imaging data (fluorescence microscopy) that make us able to experimentally determine the parameters of the model and to validate numerical results.This model has allowed us to study the degree of simultaneity of phase transitions within a proliferating cell population and to analyse the role of an increased growth factor concentration in this process.…”
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Delineating Molecular Mechanisms of Squamous Tissue Homeostasis and Neoplasia: Focus on p63 by Kathryn E. King, Linan Ha, Tura Camilli, Wendy C. Weinberg

“…These isoforms can mimic or interfere with one another, and their balance ultimately determines biological outcome in a context-dependent manner. While not frequently mutated, p63, and in particular the ΔNp63 subclass, is commonly overexpressed in human squamous cell cancers. …”
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Locally activated semisynthetic fluorescent biosensors for imaging cellular biochemistry by Coïs, Justine, Dumat, Blaise

“…Biosensors based on fluorescent proteins are widely used as genetically encoded indicators due to their capacity to target various biological analytes (metal ions, reactive oxygen species, biomolecules, etc.) within cells with precise localization. …”
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Cutting Edge PBPK Models and Analyses: Providing the Basis for Future Modeling Efforts and Bridges to Emerging Toxicology Paradigms by Jane C. Caldwell, Marina V. Evans, Kannan Krishnan

“…Specifically, issues addressed include: (a) increased understanding of human variability of pharmacokinetics and pharmacodynamics in the population, (b) exploration of mode of action hypotheses (MOA), (c) application of biological modeling in the risk assessment of individual chemicals and chemical mixtures, and (d) identification and discussion of uncertainties in the modeling process.…”
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Recurrent pregnancy loss: etiology, pathophysiology, diagnosis and treatment by Zlatko Kirovakov, Elitsa H. Gyokova, Nadezhda H. Hinkova, Emiliana I. Konova

“…The findings showed that the etiological factors can be biological, hereditary or environmental, and in approximately 50% of RPL cases, these factors remain unknown. …”
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The Reporter System for GPCR Assay with the Fission Yeast Schizosaccharomyces pombe by Shintaro Sasuga, Toshiya Osada

“…G protein-coupled receptors (GPCRs) are associated with a great variety of biological activities. Yeasts are often utilized as a host for heterologous GPCR assay. …”
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Catalytic pathways for N-arylation of benzimidazoles: A comprehensive review by Anila Ghulam, Tooba Jabeen, Sana Aslam, Matloob Ahmad, Magdi E.A. Zaki

“…The N-arylated benzimidazoles are important structural motifs in many biologically active compounds. Due to their distinct physicochemical and structural features, they have applications in a wide range of domains, including pharmaceutical chemistry, material sciences, and catalysis. …”
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Primary Acinic Cell Carcinoma of the Breast: A Clinicopathological and Immunohistochemical Study by Kiyoshi Shingu, Tokiko Ito, Gengo Kaneko, Nobuo Itoh

“…As studies on large series are lacking, further studies are needed to elucidate the biological characteristics of acinic cell carcinoma of the breast.…”
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‘An unbidden guest at your table’: Purity, danger and the house-fly in the middle-class home, c. 1870-1910 by Neil Davie

“…This in turn reflected contemporary developments in medical and biological science; along with broader attitudes to ‘cleanliness’ and ‘dirt’. …”
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Bromide-Assisted Anisotropic Growth of Gold Nanoparticles as Substrates for Surface-Enhanced Raman Scattering by Melissa A. Kerr, Fei Yan

“…The as-prepared Au NPs exhibited excellent surface-enhanced Raman scattering (SERS) properties, which make them very attractive for the development of SERS-based chemical and biological sensors.…”
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An age-structured model for the coupled dynamics of HIV and HSV-2 by Georgi Kapitanov, Christina Alvey, Katia Vogt-Geisse, Zhilan Feng

“…The calculations of the invasion reproduction numbers suggest a new aspect in their interpretation - the class from which the initial disease carrier arises is important for understanding the invasion dynamics and biological interpretation of the expressions of the reproduction numbers. …”
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Temperature and Host Fruit During Immature Development Shape Adult Life History Traits of Different <i>Ceratitis capitata</i> Populations by Georgia D. Papadogiorgou, Nikos T. Papadopoulos

“…These findings underscore how temperature and host fruit availability shape medfly invasion dynamics, highlighting the species’ biological plasticity and adaptation to different environments. …”
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A Nonoscillatory Second-Order Time-Stepping Procedure for Reaction-Diffusion Equations by Philku Lee, George V. Popescu, Seongjai Kim

“…The article also performs a sensitivity analysis for the numerical solution of biological pattern forming models to conclude that the numerical solution is much more sensitive to the spatial mesh resolution than the temporal one. …”
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A review on current and future advancements for commercialized microalgae species by Jia Fei Wong, Hui Jing Hong, Su Chern Foo, Michelle Khai Khun Yap, Ji Wei Tan

“…This review will focus on accessing the biochemical compositions of commercialised microalgae species from 2007 to 2020, and the activity of their biologically active molecules in eliciting selected therapeutic potentials which are anti-oxidative, anti-inflammatory, anti-microbial and anti-cancer properties. …”
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Glycine rich proteins of ticks: more than a cement component by Renata Perotto de Souza, Mariana Vieira Dalla Valentina, Bruna Ferreira Leal, Sílvia Dias Oliveira, Carlos Alexandre Sanchez Ferreira, Ala Tabor

“…GRPs have been identified in a diverse array of organisms and have been shown to possess a number of distinctive biological characteristics, including nucleic acid binding, adhesive glue-like properties, antimicrobial activity, involvement in the stress response and in the formation of cuticle components. …”
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Cytokine Levels in the Serum of Healthy Subjects by Giulio Kleiner, Annalisa Marcuzzi, Valentina Zanin, Lorenzo Monasta, Giorgio Zauli

“…Growing knowledge about the cytokine network response has led to a better comprehension of mechanisms of pathologies and to the development of new treatments with biological drugs, able to block specific molecules of the immune response. …”
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A resource of longitudinal RNA-seq data of Holstein cow rumen, duodenum, and colon epithelial cells during the lactation cycle by Yahui Gao, George E. Liu, Li Ma, Cong-jun Li, Ransom L Baldwin

“…Samples were taken from five multiparous dairy cows as biological replicates per tissue per stage, except for Days 14 and 28, for which the sample size was three. …”
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