Systematic dissection of pleiotropic loci and critical regulons in excitatory neurons and microglia relevant to neuropsychiatric and ocular diseases by Yunlong Ma, Dingping Jiang, Jingjing Li, Gongwei Zheng, Yao Deng, Xuanxuan Gou, Shuaishuai Gao, Cheng Chen, Yijun Zhou, Yaru Zhang, Chunyu Deng, Yinghao Yao, Haijun Han, Jianzhong Su

“…To investigate the biological connections between the eye and brain, we integrated bulk and single-cell multiomic profiles with GWAS summary statistics for eight neuropsychiatric and five ocular diseases. …”
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Ruta chalepensis L. Essential Oil: A New Antisprouting Agent for Potatoes Bioconservation by Olfa Lengliz, Jamel Mejri, Manef Abderrabba, Rachid Khalifa, Mondher Mejri

“…The main concern of this work was to find a new biological antisprouting product for potatoes during storage. …”
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Application of the Machine Learning Methods to Assess the Impact of physico-chemical characteristics of water on Feed Consumption in Fish Farms by Hava Şimşek, Mükerrem Oral, Mesut Yılmaz, Mustafa Çakır, Nedim Özdemir, Okan Oral

“…Eleven physico-chemical characteristics (temperature, pH, dissolved oxygen, electrical conductivity, salinity, Nitrite nitrogen, nitrate nitrogen, ammonium nitrogen, total phosphorus, total suspended solids, and biological oxygen demand) of water were evaluated in terms of fish feed consumption by using ML methods. …”
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A mechanism-informed deep neural network enables prioritization of regulators that drive cell state transitions by Xi Xi, Jiaqi Li, Jinmeng Jia, Qiuchen Meng, Chen Li, Xiaowo Wang, Lei Wei, Xuegong Zhang

“…This method to analyze single-cell multi-omics data demonstrates how the interpretable design of neural networks can better decode biological systems.…”
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Amino Acid-Mediated Metabolism: A New Power to Influence Properties of Stem Cells by Jilan Liu, Xianyun Qin, Dongfeng Pan, Bin Zhang, Feng Jin

“…The balance in AA metabolism is responsible for maintaining the functionality of noncancer stem cells, and altering the levels of AAs can influence the malignant biological behavior of cancer stem cells. AAs are considered nutrients participating in metabolism and playing a critical role in maintaining the activity of normal stem cells and the effect of therapy of cancer stem cells. …”
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Study on mechanism of increased allergenicity induced by Ara h 3 from roasted peanut using bone marrow-derived dendritic cells by MinJia Wang, Shuo Wang, Xiaodong Sun, ZhiRui Deng, Bing Niu, Qin Chen

“…The purpose of this study was to determine the influence of roasting (150 °C, 20 min) on biochemical and biological properties of Ara h 3, a major peanut allergen. …”
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In vivo trafficking of cancer-derived exosomes and their role in metastasis by Shih-Yen Wei, Sarah E. Shelton, Ying-Chieh Chen, Ke Huang

“…This process is driven by a combination of biological processes including invasion, intravasation, circulation, extravasation, and colonization of distant organs, among which cancer cell-derived exosomes facilitate metastasis through their enriched oncogenic miRNAs and lncRNAs to enhance cancer cell migration and invasion, promote epithelial-mesenchymal transition in recipient cells, help cancer cells evade immune detection, and alter the microenvironment to promote the formation of a pre-metastatic niche. …”
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Analysis on the Characteristics of Water Pollution Caused by Underground Mining and Research Progress of Treatment Technology by Xinfeng Wang, Yuhao Gao, Xiaojun Jiang, Qiao Zhang, Wengang Liu

“…This paper does an in-depth analysis of the physical, chemical, biological, and environmental characteristics of mine water, puts forward the basic classification of mine water, and points out the characteristics of environmental hazards of mine water. …”
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Development of Cutaneous Bioadhesive Ureasil-Polyether Hybrid Films by João Augusto Oshiro Junior, Flávia Chiva Carvalho, Christiane Pienna Soares, Marlus Chorilli, Leila Aparecida Chiavacci

“…The hydrolysis and condensation reactions involved in synthesis of ureasil-polyether films influence the film formation time and the number of chemical groups able to form hydrogen bonds, responsible for the bioadhesion, with the biological substrate. The objective of this work was to study the influence of the use of an acid catalyst (hydrochloric acid) and a basic catalyst (ammonium fluoride) in the hydrolysis and condensation reactions on the time formation and bioadhesion of ureasil-polyether films. …”
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Formulation of the protein synthesis rate with sequence information by Wenjun Xia, Jinzhi Lei

“…Translation is a central biological process by which proteins are synthesized from genetic information contained within mRNAs. …”
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Non-thermal plasma as promising anti-cancer therapy against bladder cancer by inducing DNA damage and cell cycle arrest by Jojanneke Stoof, Zakaria Kalmoua, Ana Sobota, Ruud H. Brakenhoff, Marijke Stigter, Thang V. Pham, Sander R. Piersma, Alex Henneman, Tonny Lagerweij, Richard de Goeij-de Haas, R. Jeroen A. van Moorselaar, Connie R. Jimenez, Irene V. Bijnsdorp

“…Our study aims to elucidate the biological effects of PAS on bladder cancer cell lines in vitro, as well as the combination with mitomycin C (MMC), using clinically relevant settings. …”
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Gut Microbiota and its Metabolites in Pathogenesis of NAFLD by M. S. Reshetova, O. Yu. Zolnikova, V. T. Ivashkin, K. V. Ivashkin, S. A. Appolonova, T. L. Lapina

“…Metabolites of microbial origin are important biological molecules involved in many specific reactions of the human body. …”
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Comparison of Diazinon Toxicity to Temperate and Tropical Freshwater Daphnia Species by Thanh-Luu Pham, Ha Manh Bui

“…The presence of pesticides in water bodies presents unique challenges to the ecosystem and all the life forms. Biological methods have been widely used to examine the toxic effects of various toxicants including pesticides. …”
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„Humanae vitae” odpowiedzią na współczesne sporyfilozoficzno-teologiczne oraz przypomnieniem podstawowych prawdchrześcijańskiej wiary by Ryszard Moń

“…The encyclical shows that life is a gift from God, and not the effect of biological processes. Naturally, the latter are very important, but not essential. …”
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The MAPK MEK1/2-ERK1/2 Pathway and Its Implication in Hepatocyte Cell Cycle Control by Jean-Philippe Guégan, Christophe Frémin, Georges Baffet

“…Whereas the strict specificity of action of ERK1 and ERK2 is still debated, the MAPKs may have specific biological functions under certain contexts and according to the differentiation status of the cells, notably hepatocytes. …”
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Stromal-Cell-Derived Factor-1 (SDF-1)/CXCL12 as Potential Target of Therapeutic Angiogenesis in Critical Leg Ischaemia by Teik K. Ho, X. Shiwen, D. Abraham, J. Tsui, D. Baker

“…The chemokine stromal-cell-derived factor-1 (SDF-1 aka CXCL12) is a constitutively expressed and inducible chemokine that regulates multiple physiological processes, including embryonic development and organ homeostasis. The biologic effects of SDF-1 are mediated by chemokine receptor CXCR4, a 352 amino acid rhodopsin-like transmembrane-specific G protein-coupled receptor (GPCR). …”
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Information and knowledge: an evolutionary framework for information science by Marcia J. Bates

“…In this article, the objective is to provide definitions that are usable for the physical, biological, and social meanings of the terms, covering the various senses important to our field. …”
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Applications of Amniotic Membrane in Ophthalmology – New Perspectives in the Treatment of Eye Diseases by Larysa Krajewska-Węglewicz

“…Amniotic membrane, a natural protective barrier surrounding the fetus, possesses unique biological properties, making it a promising tool in regenerative medicine. …”
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Understanding the Immune System and Biospecimen-Based Response in Glioblastoma: A Practical Guide to Utilizing Signal Redundancy for Biomarker and Immune Signature Discovery by Luke R. Jackson, Anna Erickson, Kevin Camphausen, Andra V. Krauze

“…The presence of both intra- and intertumoral heterogeneity limits understanding of biological mechanisms leading to tumor resistance, including immune escape. …”
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The Flatworm Macrostomum lignano Is a Powerful Model Organism for Ion Channel and Stem Cell Research by Daniil Simanov, Imre Mellaart-Straver, Irina Sormacheva, Eugene Berezikov

“…Here we introduce the flatworm Macrostomum lignano as a versatile model organism for addressing these topics. We discuss biological and experimental properties of M. lignano, provide an overview of the recently developed experimental tools for this animal model, and demonstrate how manipulation of membrane potential influences regeneration in M. lignano.…”
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