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14841
Nanogels Containing Foeniculum vulgare Mill. and Mentha piperita L. Essential Oils: Mosquitoes’ Repellent Activity and Antibacterial Effect
Published 2022-01-01“…Foeniculum vulgare Mill. and Mentha piperita L. are two common medicinally important plants with a wide range of biological activities such as insecticide and antibacterial effects. …”
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14842
Mutations to transcription factor MAX allosterically increase DNA selectivity by altering folding and binding pathways
Published 2025-01-01“…Abstract Understanding how proteins discriminate between preferred and non-preferred ligands (‘selectivity’) is essential for predicting biological function and a central goal of protein engineering efforts, yet the biophysical mechanisms underpinning selectivity remain poorly understood. …”
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14843
Ultramodern natural and synthetic polymer hydrogel scaffolds for articular cartilage repair and regeneration
Published 2025-02-01“…Cellular scaffolds, which are among three key elements of tissue engineering, play significant roles in the repair of damaged articular cartilage by regulating cellular responses and promoting cartilage tissue regeneration. Biological macromolecules are commonly used as scaffold materials owing to their unique properties. …”
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14844
Intralesional Spesolimab: A Novel and Effective Approach for Palmoplantar Pustulosis Treatment – A Case Report
Published 2025-01-01“…Currently, interleukin-36 receptor (IL-36R)-targeted biologics are emerging as promising treatments for PPP. …”
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14845
Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics
Published 2025-02-01“…The cGAS-STING pathway was closely associated with the malignant biological behaviors of OS cells, suggesting that targeting this pathway could be a promising therapeutic strategy. …”
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14846
Posttranslational Modifications and the Immunogenicity of Biotherapeutics
Published 2016-01-01“…These processes are species and cell specific and challenge the biopharmaceutical industry when developing a production platform for the generation of recombinant biologic therapeutics. Proteins and glycoproteins are also subject to chemical modifications (CMs) both in vivo and in vitro. …”
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14847
Revisiting Capuchin Monkeys (Cebus capucinus) and the Ancient Maya
Published 2014-02-01“…Originally refuted by Baker (1992), this paper reevaluates the evidence from both papers, taking an ethnoprimatological, four‑field approach and integrating content from cultural, biological, linguistic and archaeological anthropology to discuss evidence that capuchin monkeys (Cebus capucinus) were also found within the Maya region in ancient times. …”
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14848
Effects of Pooling Samples on the Performance of Classification Algorithms: A Comparative Study
Published 2012-01-01“…A pooling design can be used as a powerful strategy to compensate for limited amounts of samples or high biological variation. In this paper, we perform a comparative study to model and quantify the effects of virtual pooling on the performance of the widely applied classifiers, support vector machines (SVMs), random forest (RF), k-nearest neighbors (k-NN), penalized logistic regression (PLR), and prediction analysis for microarrays (PAMs). …”
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14849
Design and validation of ultra-compact metamaterial-based biosensor for non-invasive cervical cancer diagnosis in terahertz regime.
Published 2025-01-01“…It enables characterization of biological tissues and discrimination between healthy and malignant ones. …”
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14850
Secretion of One Adipokine Nampt/Visfatin Suppresses the Inflammatory Stress-Induced NF-κB Activity and Affects Nampt-Dependent Cell Viability in Huh-7 Cells
Published 2015-01-01“…Nampt/visfatin acts in both intracellular and extracellular compartments to regulate multiple biological roles, including NAD metabolism, cancer, inflammation, and senescence. …”
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14851
Global language geography and language history: challenges and opportunities [version 2; peer review: 1 approved, 3 approved with reservations]
Published 2025-01-01“…This new perspective is also able to address the striking correlation between linguistic and biological diversity that suggest that the processes that created and maintain both are, on some level, qualitatively similar.…”
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14852
Matrix metalloproteinase-3 is a potent prognostic factor associated with cell proliferation and migration in prostate cancer
Published 2025-03-01“…However, the clinical and biological significance of MMP3 has not been well elucidated.We therefore immunolocalized MMP3 in prostate cancer tissues (n = 117) and demonstrated that MMP3 immunoreactivity was correlated with aggressive phenotype of prostate cancer, including higher proliferation/invasion ability, and shorter disease-free survival. …”
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14853
Edaphic Diversity, Polychemical Soil Status of the Prinevskaya Lowland and Prospects for Soils Use
Published 2025-01-01“…Studies were carried out using morphological descriptions and analyses of chemical, physical, and biological properties. The most vulnerable land use are forest and agricultural and fallow zones, where active accumulation of priority toxicants of anthropogenic origin can occur. …”
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14854
A Case of Chemotherapy-Refractory “THRLBCL like Transformation of NLPHL” Successfully Treated with Lenalidomide
Published 2018-01-01“…Despite having a phenotypic resemblance, they have distinct biologic behavior and clinical course. NLPHL typically has an indolent course, and THRLBCL has an aggressive course. …”
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14855
Desulfurization Capabilities of Indigenous Bacteria Isolates for Enhanced Sulfur Removal
Published 2024-12-01“…Biocatalytic desulfurization methods potentially promote energy savings due to the mild temperature, and low-pressure operating conditions involved. Furthermore, the biological process results in a negligible level of undesirable products and emissions without lowering the calorific value of the fuel. …”
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14856
Scorpion Venom and the Inflammatory Response
Published 2010-01-01“…Scorpion venoms consist of a complex of several toxins that exhibit a wide range of biological properties and actions, as well as chemical compositions, toxicity, and pharmacokinetic and pharmacodynamic characteristics. …”
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14857
Mesenchymal Stem Cells for the Treatment of Spinal Arthrodesis: From Preclinical Research to Clinical Scenario
Published 2017-01-01“…The review has yielded promising evidence supporting the use of MSCs as a cell-based therapy in spinal fusion procedures, thus representing a suitable biological approach able to reduce the high cost of osteoinductive factors as well as the high dose needed to induce bone formation. …”
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14858
Sounds of the northern Andes: the calls of a diverse and endangered frog community (Amphibia, Anura) from Ecuador
Published 2025-01-01“…The emission of calls is one of the most distinctive and important reproductive traits in anurans. Given the biological significance of vocalizations, this trait is also useful for identification proposes and is key in recognizing cryptic diversity. …”
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14859
Application of Multilevel Models to Morphometric Data. Part 2. Correlations
Published 2003-01-01“…., within‐tumor) correlations seem to be of major interest. Beside their biological importance, these correlation coefficients (CC) are compulsory when dimensionality reduction is required. …”
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14860
Arystotelesowsko-tomistyczny obraz świata w ujęciu Piotra Lenartowicza SJ a naukowy obraz świata. Aspekty metanaukowe
Published 2019-06-01“…Celem artykułu jest rekonstrukcja obrazu świata, który w swoich analizach filozoficznych zakładał krakowski jezuita – filozof i biolog – Piotr Lenartowicz SJ. Rekonstrukcja pokazała, że autor przyjmował arystotelesowsko-tomistyczny obraz świata, w którym naczelną rolę odgrywała kategoria substancji, której heurystyczna rola ujawnia się, w sposób szczególny, w opisie i wyjaśnieniu dynamiki życia biologicznego. …”
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