Pseudotyped Viruses: A Useful Platform for Pre-Clinical Studies Conducted in a BSL-2 Laboratory Setting by Sofiia N. Rizatdinova, Alina E. Ershova, Irina V. Astrakhantseva

“…In particular, the study of highly pathogenic viruses requires methods with low biological risk but relatively high sensitivity and convenience in detection. …”
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LARP3 inhibits the apoptosis of hepatocellular carcinoma via the ROS/PI3K/c-Fos axis. by Lin Zhu, Qianqian Meng, Weiyi Qian, Weiting Shao, Yuyue Lu, Shuai Jin, Afei Zhang, Shuang G Yan, Jingtao Lu

“…Through cellular experiments such as gene editing and phenotypic functions, we found that LARP3 promotes the occurrence and development of HCC and inhibits apoptosis. Finally, through biological means such as RNA sequencing, flow cytometry, western blotting, and the construction of a subcutaneous tumorigenesis model in nude mice, we concluded that inhibition of HCC apoptosis by LARP3 is related to LARP3 negatively regulating ROS level and inhibiting the PI3K/c-Fos/apoptosis axis. …”
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Cell-Oriented Modeling of Angiogenesis by Diego Guidolin, Piera Rebuffat, Giovanna Albertin

“…Due to its significant involvement in various physiological and pathological conditions, angiogenesis (the development of new blood vessels from an existing vasculature) represents an important area of the actual biological research and a field in which mathematical modeling proved particularly useful in supporting the experimental work. …”
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Synthesis of antifungal imines as inhibitors of ergosterol biosynthesis by Joydeep Karan, Aditi Kundu, Robin Gogoi, Kanchikeri Math Manjaiah, Ashutosh Kumar Singh, Koyel Mondal, Rajesh Kumar, Parshant Kaushik, Priya Saini, Virendra Singh Rana, Najam Akhtar Shakil

“…Because of their broad biological relevance, imines are a promising target for fungicide development. …”
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Antimicrobial Ionic Liquids with Fumarate Anion by Biyan He, Guangnan Ou, Changyi Zhou, Meihong Wang, Suyan Chen

“…Ionic liquids are known as designed liquids with controllable physical/chemical/biological properties and specific functions, which have been attracting considerable interest over recent years. …”
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Combined Effect of Lentinan and Cisplatin on Cytokines IL-6, TNF-α, and TGF-β in Tumor Therapy by Xu-dong Liu, Min Li, Wan-xiang Li, Qing-yu Wang, Hong-xia Zhang

“…Lentinan is a biologically active ingredient isolated from the fruiting body of Lentinula edodes (shiitake) and has antitumor properties. …”
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Utilizing Feature Selection Techniques for AI-Driven Tumor Subtype Classification: Enhancing Precision in Cancer Diagnostics by Jihan Wang, Zhengxiang Zhang, Yangyang Wang

“…Cancer’s heterogeneity presents significant challenges in accurate diagnosis and effective treatment, including the complexity of identifying tumor subtypes and their diverse biological behaviors. This review examines how feature selection techniques address these challenges by improving the interpretability and performance of machine learning (ML) models in high-dimensional datasets. …”
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Recent research progress on metal ions and metal-based nanomaterials in tumor therapy by Yongcheng Xu, Aikebaier Reheman, Wenhua Feng, Wenhua Feng, Wenhua Feng

“…Metal-based nanomaterials possess unique physical, chemical, and biological properties, providing new ideas and methods for tumor treatment. …”
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Analytical Methods to Characterize and Purify Polymeric Nanoparticles by Cristina Fornaguera, Conxita Solans

“…., size and surface charge), characterization of nanomaterials interactions with biological components (e.g., proteins from the blood), and analytical characterization and purification methods. …”
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Design of 3‐aminophenol‐grafted polymer‐modified zinc sulphide nanoparticles as drug delivery system by Milad Abniki, Zahra Azizi, Homayon Ahmad Panahi

“…The famotidine‐releasing process was investigated in simulated biological fluids (intestinal fluid at pH of 7.4 and gastric fluid at pH of 1.2) and demonstrated 65% and 73% famotidine release during periods of 30 h (pH = 7.4) and 60 min (pH = 1.2), respectively. …”
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Sesquiterpenoids from <i>Dysoxylum amooroides</i> Stem Bark: Isolation, Structure Determination, and Cytotoxicity Against MCF-7 Breast Cancer Cells by Latifah Gunawan, Hidayat Nurul Mustofa, Al Arofatus Naini, Desi Harneti, Ace Tatang Hidayat, Nurlelasari Nurlelasari, Rani Maharani, Tri Mayanti, Sofa Fajriah, Khalijah Awang, Mohamad Nurul Azmi, Unang Supratman

“…A brief structure-activity relationship and comparison with the previous works were also discussed to understand better the role of guaiane- and aromadendrane-type sesquiterpenoids in the biological activity perspective.…”
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A Network Pharmacology Study and Experimental Validation to Identify the Potential Mechanism of Heparan Sulfate on Alzheimer’s Disease-Related Neuroinflammation by Dong-Uk Kim, Bitna Kweon, Jinyoung Oh, Yebin Lim, Gyeongran Noh, Jihyun Yu, Hyang-Rin Kang, Tackmin Kwon, Kwang youll Lee, Gi-Sang Bae

“…Background/Objectives: Heparan sulfate (HS) is a polysaccharide that is found on the surface of cells and has various biological functions in the body. Methods: The purpose of this study was to predict the pharmacological effects and molecular mechanisms of HS on Alzheimer’s disease (AD) and neuroinflammation (NI) through a network pharmacology analysis and to experimentally verify them. …”
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A climatically significant abiotic mechanism driving carbon loss and nitrogen limitation in peat bogs by Alexandra B. Cory, Rachel M. Wilson, M. Elizabeth Holmes, William J. Riley, Yueh-Fen Li, Malak M. Tfaily, Sarah C. Bagby, Isogenie Field Team, EMERGE Project Coordinators, Patrick M. Crill, Jessica G. Ernakovich, Virginia I. Rich, Jeffrey P. Chanton

“…Numerous sterility assessments rule out biological contamination or extracellular enzyme activity as significant sources of this CO2. …”
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Polymeric Scaffolds in Tissue Engineering Application: A Review by Brahatheeswaran Dhandayuthapani, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar

“…In recent years, considerable interest has been given to biologically active scaffolds which are based on similar analogs of the extracellular matrix that have induced synthesis of tissues and organs. …”
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Measurements of Soil Surface Roughness During the Fourth Microwave Water and Energy Balance Experiment: April 18 through June 13, 2005 by Mi-joung Jang, Kai-Jen Calvin Tien, Joaquin Casanova, Jasmeet Judge

“…This document is Circular 1483, one of a series of the Department of Agricultural and Biological Engineering, UF/IFAS Extension. Original publication date November 2005.  …”
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The role of oxidative stress, glucocorticoid receptor and ARMC5 in lipid metabolism by Yosuke Okuno, Atsunori Fukuhara, Iichiro Shimomura

“…Lipid metabolism includes lipogenesis, lipolysis, and cholesterol metabolism and it exerts a wide range of biological effects. We previously found novel roles of adipocyte oxidative stress in diet-induced obesity, adipocyte glucocorticoid receptor in Cushing syndrome, and ARMC5 in adrenocortical cells. …”
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Advances and Mechanisms of RNA–Ligand Interaction Predictions by Chen Zhuo, Chengwei Zeng, Haoquan Liu, Huiwen Wang, Yunhui Peng, Yunjie Zhao

“…Therefore, studying RNA–ligand interactions is essential for understanding biological processes. In this review, we analyze the interaction characteristics of RNA–ligand complexes by examining RNA’s sequence, secondary structure, and tertiary structure. …”
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Ephedra extract-mediated gold nanoparticles on Kaolin: A natural approach for reduction and stabilization, with evaluation of antioxidant and anti-ovarian cancer activities by Hui Yang, Cui Wang, Qingjiang Wang, Feng Han

“…An analysis of the Au NPs/Kaolin composite's structural properties was conducted using FE-SEM, TEM, EDX, and XRD assays. The biological activity of the composite was evaluated through cytotoxicity tests using the MTT assay. …”
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Alternative 3′ UTR polyadenylation is disrupted in the rNLS8 mouse model of ALS/FTLD by Randall J. Eck, Paul N. Valdmanis, Nicole F. Liachko, Brian C. Kraemer

“…Some conservation exists between alternative polyadenylation in rNLS8 mice and human disease models including in disease relevant genes and biological pathways. Together, these findings support both TDP-43 loss and toxic gain-of-function phenotypes as contributors to the neurodegeneration in rNLS8 mice, nominating its continued utility as a preclinical model for investigating mechanisms of neurodegeneration in ALS/FTLD-TDP.…”
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Enhancement of Fluorescent Labeling via a Composited Thin Film by Taikei Suyama, Xiaowei Ji, Yaoju Zhang

“…Fluorescent labeling is the prevailing imaging technique in cell biological research. When statistical investigations on a large number of cells are involved, experimental study is required for both low magnification to get a reliable statistical population and high contrast to achieve accurate diagnosis on the nature of the cells’ perturbation. …”
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