Global sensitivity analysis and uncertainty quantification for a mathematical model of dry anaerobic digestion in plug-flow reactors by Daniele Bernardo Panaro, Andrea Trucchia, Vincenzo Luongo, Maria Rosaria Mattei, Luigi Frunzo

“…In many applications, complex biological phenomena can be reproduced via structured mathematical models, which depend on numerous biotic and abiotic input parameters, whose effect on model outputs can be of paramount importance. …”
Get full text

Blue elixir of youth and wellness: The multicomponent-multitarget paradigm of Curcuma caesia Roxb by Sabrina Burattini, Federico Gianfanti, Francesco Onesimo, Sabrina Donati Zeppa, Barbara Canonico, Mariele Montanari, Giovanna Panza, Daniele Lopez, Giosuè Annibalini, Fabiana Fanelli, Roberta Saltarelli, Michele Mari, Michele Retini, Riham Osman, Aghna Mariam, Matteo Micucci, Giovanni Caprioli, Agnese Santanatoglia, Deborah Agostini, Michela Battistelli

“…Aging is a complex biological process influenced by genetic, environmental, and lifestyle factors, including diet and exercise. …”
Get full text

Agrowaste bioconversion and microbial fortification have prospects for soil health, crop productivity, and eco-enterprising by Dhananjaya P. Singh, Ratna Prabha, Shukla Renu, Pramod Kumar Sahu, Vivek Singh

“…Abstract Purpose Agricultural chemicals either used as nutrient inputs for soil fertility or pesticides are creating physicochemical and biological deterioration of the soils and disturbing the agro-ecosystems worldwide. …”
Get full text

Integrating MAPK pathway inhibition into standard-of-care therapy for pediatric low-grade glioma by Erin E. Crotty, Aimee A. Sato, Aimee A. Sato, Mohamed S. Abdelbaki

“…We discuss the potential for more expansive or histology-agnostic tumor targeting using MEK inhibitors, harnessing their biologic relevance for other RAS-altered conditions.…”
Get full text

Genome-Wide Expression Difference of MicroRNAs in Basal Cell Carcinoma by Hai-Peng Wei, Song Zhan, Qing-An Zhu, Zhen-Juan Chen, Xian Feng, Jun-Yuan Chen, Qi-Lin Zhang, Jingjie Zhao, Lingzhang Meng

“…After six small RNA sequencing- (sRNA-seq-) based miRNA expression profiles were generated for both BCC and controls, including three biological replicates, we conducted comparative analysis on the sRNA-seq dataset, discovering 181 differentially expressed miRNAs (DEMs) out of the 1,873 miRNAs in BCCs. …”
Get full text

Transcription factor TCF4: structure, function, and associated diseases by R. R. Savchenko, N. A. Skryabin

“…This hinders progress in basic and applied biological and medical sciences, especially in treating hereditary diseases, which are caused by mutations and polymorphic variants in individual genes. …”
Get full text

Bioactivity of plants used traditionally in the treatment and management of men’s sexual health by Tsumbedzo Nemandalali, Monde A. Nyila, Thilivhali E. Tshikalange

“…Aim: The study evaluated biological activities of 10 ethnobotanically selected medicinal plants. …”
Get full text

NIPAL1 as a prognostic biomarker associated with pancreatic adenocarcinoma progression and immune infiltration by Youlong Zhu, Zongze Qi, Shaoqi Zu, Fangchao Yang, Yanming Wang, Lei Zhu, Xintong Li, Ruixue Li, Hong Zhu

“…Differentially expressed genes (DEGs) were identified, and Gene Set Enrichment Analysis (GSEA) was performed to elucidate potential biological mechanisms of NIPAL1 involved in PAAD development. …”
Get full text

Cellulase-Assisted Extraction, Characterization, and Bioactivity against Rheumatoid Arthritis of Astragalus Polysaccharides by Ling Cao, Mi Yu, Chonghui Wang, Yunhui Bao, Minghui Zhang, Ping He, Yan Zhang, Tingting Yang, Lulu Li, Gang Li, Yun Gong

“…This study investigated the effect of cellulase on the isolation of crude Astragalus polysaccharide (APS), analyzed the monosaccharide component of deproteinized APS, detected the molecular weights of purified APS, and examined the biological activities and the preliminary mechanism against rheumatoid arthritis (RA). …”
Get full text

The process of obtaining information about COVID-19 among students of physiotherapy and rehabilitation department by Duygu Ilgin Gunduz, Erhan Secer, Melda Baser Secer

“…Students’ sociodemographic data (age, biological sex, body mass index) and the main topics they researched about COVID-19, information sources, and factors influencing their choice of sources were recorded. …”
Get full text

Performance Evaluation of Produced Water Quality from a Nearshore Oil Treatment Facility by DBM Nwokoma, KK Dagde

“…Parameters examined were Temperature, pH, Oil and Grease, Total Dissolved Solids TDS, Total Suspended Solids TSS, Biological Oxygen Demand BOD5. The average temperature of the produced water was reduced from 42.0oC to 25.9oC. …”
Get full text

Deciphering the potential of plant metabolites as insecticides against melon fly (Zeugodacus cucurbitae): Exposing control alternatives to assure food security by Zinat Jahan Chowdhury, Anik Banik, Tanjin Barketullah Robin, Mohammed Rashed Chowdhury

“…In the absence of effective biological or chemical controls, the melon fly poses a significant threat to food security, particularly impacting cucurbit crops in tropical and subtropical regions. …”
Get full text

High expression of SULF1 is associated with adverse prognosis in breast cancer brain metastasis by Yitong Li, Tingting Feng, Qinghong Wang, Yue Wu, Jue Wang, Wenlong Zhang, Qi Kong

“…However, research on the biological mechanisms of breast cancer brain metastasis and potential therapeutic targets are limited. …”
Get full text

Secukinumab Treatment in Patients With Hidradenitis Suppurativa in Real-World Clinical Settings: A Multicenter Study by Ece Erbağcı, Özge Sevil Karstarlı Bakay, Fatma Aslı Hapa

“…Nine (29%) patients were biologic-naive and 10 (32.3%) were adalimumab-naive. …”
Get full text

Habit of elongate amphibole particles as a predictor of mesothelial carcinogenicity by Andrey A. Korchevskiy, Ann G. Wylie

“…Conclusions: The habit of amphibole particles is predictive of biological behavior that can be estimated from the dimensional data for the particles.…”
Get full text

Optimization of cultivation parameters for bovine respiratory syncytial virus strain Vologda/2019 by V. V. Kirpichenko, S. V. Kononova, I. N. Shumilova, A. A. Nesterov, M. V. Turkova, Ye. A. Bukhon, D. V. Romenskaya, A. V. Sprygin, B. L. Manin, O. P. Byadovskaya

“…The Vologda/2019 strain of the bovine respiratory syncytial infection virus isolated from biological material obtained from a calf with respiratory symptoms was used in the experiment. …”
Get full text

Long-Term Outcomes of Osteochondral Allograft with Osteogenic Protein-1 Augmentation: A Twelve-Year Follow-Up by Eric Assid, Andrew Renshaw, Mawadah Samad, Richard Tupler, Deryk Jones

“…Pulse lavage and carbon dioxide have been used to remove marrow elements from the superficial, middle, and deep layers of the allograft; this has been combined with the use of various biologics such as bone marrow aspirate or whole blood to augment donor bone incorporation into the host bone. …”
Get full text

Performance Evaluation of Produced Water Quality from a Nearshore Oil Treatment Facility by DBM Nwokoma, KK Dagde

“…Parameters examined were Temperature, pH, Oil and Grease, Total Dissolved Solids TDS, Total Suspended Solids TSS, Biological Oxygen Demand BOD5. The average temperature of the produced water was reduced from 42.0oC to 25.9oC. …”
Get full text

The human‐specific noncoding RNA RP11‐424G14.1 functions at the intersection of sexually dimorphic pathways in inflammation, senescence, and metabolism by Kameron Kennicott, Yun Liang

“…Microarray study suggests the NF‐κB pathway as the top biological pathway affected by RP11‐424G14.1 knockdown, consistent with known sex differences in inflammation. …”
Get full text

Natural population cohort study on long-lived adults: West China longevity and ageing procedure (WCLAP) by Li Wang, Yan Zhang, Qiukui Hao, Xiaoyan Chen, Birong Dong, Yan He, Meijuan Chen, Jirong Yue, Xiaochu Wu, Tianyao Zhang, Yan She, Yanling Gao, Yiping Deng

“…Data collection included a comprehensive assessment of the participant’s health (including physical, psychological, social and common chronic disease assessments), instrumental tests (body composition and muscle percentage) and the collection of biomedical-biobank samples (include blood, urine, faeces, hair and urine).Future plans Through the annual cohort follow-up, survival-related information is collected at a group level. Analysis of biological samples facilitates biological characterisation at the microscopic level through proteomics, metabolomics, genomics and other techniques. …”
Get full text