Flavones enrich rhizosphere Pseudomonas to enhance nitrogen utilization and secondary root growth in Populus by Jiadong Wu, Sijia Liu, Haoyu Zhang, Sisi Chen, Jingna Si, Lin Liu, Yue Wang, Shuxian Tan, Yuxin Du, Zhelun Jin, Jianbo Xie, Deqiang Zhang

Get full text

Corpses, Embryos, Animal by E. V. Loginov

“…From this it follows that we should accept the biological approach; the persistence condition for me is a Life. …”
Get full text

The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells by Sabrina Bimonte, Antonio Barbieri, Maddalena Leongito, Giuseppe Palma, Vitale del Vecchio, Michela Falco, Raffaele Palaia, Vittorio Albino, Mauro Piccirillo, Alfonso Amore, Antonella Petrillo, Vincenza Granata, Francesco Izzo

“…In this review, we synthesize the latest findings on the role of miRNAs in regulating different biological properties of pancreatic cancer stem cells.…”
Get full text

Synthesis, Cytotoxicity, and Antileishmanial Activity of N,N'-Disubstituted Ethylenediamine and Imidazolidine Derivatives by Gustavo S. G. de Carvalho, Patrícia A. Machado, Daniela T. S. de Paula, Elaine S. Coimbra, Adilson D. da Silva

“…The leishmanicidal activity can be related with inhibition of polyamine synthesis and cellular penetration within biological membranes.…”
Get full text

RETRACTED: Di Paola et al. Combined Toxicity of Xenobiotics Bisphenol A and Heavy Metals on Zebrafish Embryos (<i>Danio rerio</i>). <i>Toxics</i> 2021, <i>9</i>, 344 by Davide Di Paola, Fabiano Capparucci, Giovanni Lanteri, Marika Cordaro, Rosalia Crupi, Rosalba Siracusa, Ramona D’Amico, Roberta Fusco, Daniela Impellizzeri, Salvatore Cuzzocrea, Nunziacarla Spanò, Enrico Gugliandolo, Alessio Filippo Peritore

Get full text

Differential Expression of -Associated Genes in Autosomal Dominant Polycystic Kidney Disease by Yeon Joo Yook, Yu Mi Woo, Moon Hee Yang, Je Yeong Ko, Bo Hye Kim, Eun Ji Lee, Eun Sun Chang, Min Joo Lee, Sunyoung Lee, Jong Hoon Park

“…The majority of identified mutations was involved in critical biological processes, such as metabolism, transcription, cell adhesion, cell cycle, and signal transduction. …”
Get full text

Correction: Zandberg et al. The Global Assessment of Oilseed Brassica Crop Species Yield, Yield Stability and the Underlying Genetics. <i>Plants</i> 2022, <i>11</i>, 2740 by Jaco D. Zandberg, Cassandria T. Fernandez, Monica F. Danilevicz, William J. W. Thomas, David Edwards, Jacqueline Batley

Get full text

Multiple blood feeding bouts in mosquitoes allow for prolonged survival and are predicted to increase viral transmission during dry periods by Christopher J. Holmes, Souvik Chakraborty, Oluwaseun M. Ajayi, Melissa R. Uhran, Ronja Frigard, Crystal L. Stacey, Emily E. Susanto, Shyh-Chi Chen, Jason L. Rasgon, Matthew DeGennaro, Yanyu Xiao, Joshua B. Benoit

Get full text

Bionic Nonsmooth Drag Reduction Mathematical Model Construction and Subsoiling Verification by Baoguang Wu, Ruize Zhang, Pengfei Hou, Jin Tong, Deyi Zhou, Haiye Yu, Qiang Zhang, Jinsong Zhang, Yuelin Xin

Get full text

Erratum to “Epithelial Cells Attenuate Toll-Like Receptor-Mediated Inflammatory Responses in Monocyte-Derived Macrophage-Like Cells to Mycobacterium tuberculosis by Modulating the... by Yi Yang, Yingfei Sun, Jinrui Xu, Kangda Bao, Meihui Luo, Xiaoming Liu, Yujiong Wang

Get full text

In silico methods for immunogenicity risk assessment and human homology screening for therapeutic antibodies by Aimee E. Mattei, Andres H. Gutierrez, Soorya Seshadri, Jacob Tivin, Matt Ardito, Amy S. Rosenberg, William D. Martin, Anne S. De Groot

“…In silico immunogenicity risk assessment has been an important step in the development path for many biologic therapeutics, including monoclonal antibodies. …”
Get full text

A sensitivity analysis of methodological variables associated with microbiome measurements by Samuel P. Forry, Stephanie L. Servetas, Jennifer N. Dootz, Monique E. Hunter, Jason G. Kralj, James J. Filliben, Scott A. Jackson

“…In this study, a full factorial experimental design was used to compare the effects of a select set of methodological choices (sample, operator, lot, extraction kit, variable region, and reference database) on the analysis of biologically diverse stool samples. For each parameter investigated, a main effect was calculated that allowed direct comparison both between methodological choices (bias effects) and between samples (real biological differences). …”
Get full text

“One Ring to Bind Them All”—Part I: The Efficiency of the Macrocyclic Scaffold for G-Quadruplex DNA Recognition by David Monchaud, Anton Granzhan, Nicolas Saettel, Aurore Guédin, Jean-Louis Mergny, Marie-Paule Teulade-Fichou

“…Stimulated by the pioneering studies on the cationic porphyrin TMPyP4 and the natural product telomestatin, follow-up studies have developed, rapidly leading to a large diversity of macrocyclic structures with remarkable-quadruplex binding properties and biological activities. In this review we summarize the current state of the art in detailing the three main categories of quadruplex-binding macrocycles described so far (telomestatin-like polyheteroarenes, porphyrins and derivatives, polyammonium cyclophanes), and in addressing both synthetic issues and biological aspects.…”
Get full text

Biosynthesis of Metal Nanoparticles: A Review by Narendra Kulkarni, Uday Muddapur

“…The biomineralization of nanoparticles in protein cages is one of such biological approaches used in the generation of nanoparticles. …”
Get full text

Photobiomodulation Process by Yang-Yi Xu, Timon Cheng-Yi Liu, Lei Cheng

“…There may be a dose zone in which low intensity LI (LIL at different doses) has biological effects similar to each other, so that biological information model of PBM might hold. …”
Get full text

Inefficacy or Paradoxical Effect? Uveitis in Ankylosing Spondylitis Treated with Etanercept by Bernd Raffeiner, Francesca Ometto, Livio Bernardi, Costantino Botsios, Leonardo Punzi

“…Uveitis is a severe and rather specific manifestation of AS. Biologics targeting tumor necrosis factor (TNF) α are effective on both articular and ocular manifestations of disease. …”
Get full text

Molecular Modeling Studies of Some Uracil and New Deoxyuridine Derivatives by Yousra Abdel-Mottaleb, M. S. A. Abdel-Mottaleb

“…Molecular modeling results reported in this paper are crucial in highlighting the quantitative relationship between the optimized structure and computed molecular properties related to four newly synthesized uracil derivatives with promising biological potential as anticancer bioactive agents. …”
Get full text

Generation of slow phase-locked oscillation and variability of the interspike intervals in globally coupled neuronal oscillators by Ryotaro Tsuneki, Shinji Doi, Junko Inoue

“…To elucidate how a biological rhythm is regulated,the extended (three-dimensional) Bonhoeffer-van der Pol or FitzHugh-Nagumo equations are employed toinvestigate the dynamics of a population of neuronal oscillators globally coupled through a common buffer (mean field).Interesting phenomena, such as extraordinarily slow phase-locked oscillations (compared to the natural period of each neuronal oscillator)and the death of all oscillations, are observed.We demonstrate that the slow synchronization is due mainly to the existence of ``fast&quot; oscillators.Additionally, we examine the effect of noise on the synchronization and variability of the interspike intervals.Peculiar phenomena, such as noise-induced acceleration and deceleration, are observed.The results herein suggest that very small noise may significantly influence a biological rhythm.…”
Get full text

Synthesis, Crystal Structure, and DNA-Binding Studies of a Nickel(II) Complex with the Bis(2-benzimidazolymethyl)amine Ligand by Huilu Wu, Tao Sun, Ke Li, Bin Liu, Fan Kou, Fei Jia, Jingkun Yuan, Ying Bai

Get full text

IL-2-armored peptide-major histocompatibility class I bispecific antibodies redirect antiviral effector memory CD8+ T cells to induce potent anti-cancer cytotoxic activity with lim... by John S. Schardt, Even Walseng, Kim Le, Chunning Yang, Pooja Shah, Ying Fu, Kausar Alam, Cathryn R. Kelton, Yu Gu, Fengying Huang, Jia Lin, Wenhai Liu, Andrew Dippel, Hanzhi Zhang, Kathy Mulgrew, Stacy Pryts, Vijaykumar Chennupati, Hung-Chang Chen, Jessica Denham, Xiaoru Chen, Pallab Pradhan, Yuling Wu, Colin Hardman, Chihao Zhao, Michael Kierny, Yang Song, Simon J. Dovedi, Saso Cemerski, Yariv Mazor

“…T cell engagers (TCEs) are becoming an integral class of biological therapeutic owing to their highly potent ability to eradicate cancer cells. …”
Get full text