Polymerized-Type I Collagen Downregulates Inflammation and Improves Clinical Outcomes in Patients with Symptomatic Knee Osteoarthritis Following Arthroscopic Lavage: A Randomized,... by Janette Furuzawa-Carballeda, Guadalupe Lima, Luis Llorente, Carlos Nuñez-Álvarez, Blanca H. Ruiz-Ordaz, Santiago Echevarría-Zuno, Virgilio Hernández-Cuevas

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A Retrospective Study on Amoxicillin Susceptibility in Severe Haemophilus influenzae Pneumonia by Pierre Danneels, Maria Concetta Postorino, Alessio Strazzulla, Nabil Belfeki, Aurelia Pitch, Frank Pourcine, Sebastien Jochmans, Vincent Dubée, Mehran Monchi, Sylvain Diamantis

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Microvascular dysfunction in a murine model of Alzheimer’s disease using intravital microscopy by Danielle Sidsworth, Noah Tregobov, Noah Tregobov, Colin Jamieson, Jennifer Reutens-Hernandez, Joshua Yoon, Geoffrey W. Payne, Geoffrey W. Payne, Stephanie L. Sellers, Stephanie L. Sellers, Stephanie L. Sellers, Stephanie L. Sellers

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As “pegadas avaliativas” de projetos de educação em ciências envolvendo cooperação: revisão da literatura (2000-2022) by Helena Isabel Caçador, Betina Silva Lopes, Rafael Galupa, Olga † Santos, Mariana R. P. Alves

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NKp46 enhances type 1 innate lymphoid cell proliferation and function and anti-acute myeloid leukemia activity by Rui Ma, Zhenlong Li, Hejun Tang, Xiaojin Wu, Lei Tian, Zahir Shah, Ningyuan Liu, Tasha Barr, Jianying Zhang, Sean Wang, Srividya Swaminathan, Guido Marcucci, Yong Peng, Michael A. Caligiuri, Jianhua Yu

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Connotation, research status, and development directions of clean coal geology in China by Yuegang TANG, Shaoqing WANG, Xiaoshuai WANG, Xin GUO, Yafeng WANG, Liping XUE, Harold H. Schobert

“…[Issues and Prospects] This study proposes some scientific and technical problems concerning coal formation, organic/inorganic elements, minerals, and clean assessment, positing that future advancements in chemistry, physics, biology, and big data/artificial intelligence (AI) will bring opportunities for the further development of clean coal geology and its applications in large-scale engineering. …”
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Integrative genomic analyses combined with molecular dynamics simulations reveal the impact of deleterious mutations of Bcl-2 gene on the apoptotic machinery and implications in ca... by Ghazi Elamin, Ghazi Elamin, Zhichao Zhang, Depika Dwarka, Kabange Kasumbwe, John Mellem, Nompumelelo P. Mkhwanazi, Paradise Madlala, Paradise Madlala, Mahmoud E. S. Soliman

“…Therefore, integrative multifaceted approaches are crucial to understanding the complex nature of cancer biology. Bcl-2 (B-cell lymphoma 2), encoded by the human Bcl-2 gene, is a critical anti-apoptotic protein that regulates cell death pathways, primarily by inhibiting apoptosis. …”
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Inhibition of programmed cell death by melanoma cell subpopulations reveals mechanisms of melanoma metastasis and potential therapeutic targets by Yuepeng An, Fu Zhao, Hongling Jia, Siyu Meng, Ziwei Zhang, Shuxiao Li, Jiusi Zhao

“…These unique features highlighted the challenges of treating melanoma and underscored the importance of advanced tools, such as single-cell sequencing, to unravel its biology and develop personalized therapeutic strategies. …”
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Genome-wide association study analysis of single nucleotide variants in L. infantum associated with IL-6 inflammatory response in visceral leishmaniasis by Amanda Miranda da Silva, Kátia Silene Sousa Carvalho, Caio Andrey Bezerra Januário, Raquel Gomes de Sena Carneiro Caldas, Bianka Lopes da Silva Paulino, Débora Cavalcante Braz, Dorcas Lamounier Costa, Gabriel da Luz Wallau, Wilson Jose da Silva Junior, Carlos Henrique Nery Costa

“…Further research into the biological role of these variants may lead to new therapeutic targets and improve the clinical management of VL, especially in identifying high-risk patients.…”
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Human Umbilical Cord-Derived Mesenchymal Stem Cell Therapy Ameliorates Nonalcoholic Fatty Liver Disease in Obese Type 2 Diabetic Mice by Bing Li, Yu Cheng, Songyan Yu, Li Zang, Yaqi Yin, Jiejie Liu, Lin Zhang, Yiming Mu

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Kombucha Versus Vegetal Cellulose for Affordable Mucoadhesive (nano)Formulations by Ioana Popa-Tudor, Naomi Tritean, Ștefan-Ovidiu Dima, Bogdan Trică, Marius Ghiurea, Anisoara Cimpean, Florin Oancea, Diana Constantinescu-Aruxandei

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Integrated bioinformatics analysis of the effects of chronic pain on patients with spinal cord injury by Jinlong Zhang, Jinlong Zhang, Longju Qi, Yuyu Sun, Yuyu Sun, Shiyuan Chen, Jinyi Liu, Jiaxi Chen, Fangsu Yan, Wenqi Wang, Qinghua Wang, Liang Chen

“…To address this, we conducted bioinformatics and systems biology analyses to identify molecular biomarkers and pathways that link SCI to chronic pain. …”
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Mitochondrial Gene Expression of Three Different Dragonflies Under the Stress of Chlorpyrifos by Yuxin Chen, Ziwen Yang, Zhiqiang Guo, Lemei Zhan, Kenneth B. Storey, Danna Yu, Jiayong Zhang

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OMIC Technologies and Vaccine Development: From the Identification of Vulnerable Individuals to the Formulation of Invulnerable Vaccines by Nicola Cotugno, Alessandra Ruggiero, Veronica Santilli, Emma Concetta Manno, Salvatore Rocca, Sonia Zicari, Donato Amodio, Manuela Colucci, Paolo Rossi, Ofer Levy, Federico Martinon-Torres, Andrew J. Pollard, Paolo Palma

“…Finally, we will discuss how system biology “OMICs” data can be used to design bioinformatic tools to predict the vaccination outcome providing genetic and molecular “signatures” of protective immune response. …”
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Bradykinin B1 receptor signaling triggers complement activation on endothelial cells by Ingrid Lopatko Fagerström, Alexandra Gerogianni, Markus Wendler, Ida Arvidsson, Ashmita Tontanahal, Ann-Charlotte Kristoffersson, Fatimunnisa Qadri, Michael Bader, Michael Bader, Michael Bader, Michael Bader, Michael Bader, Diana Karpman

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The Influence of Posterior Class II Composite Restoration Location and Techniques on Marginal Sealing by Mishel Haddad, Diva Lugassy, Mohana Barhum, Tamar Brosh, Shlomo Matalon

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Transcriptome Analysis Reveals Key Genes Involved in the Response of <i>Triticum urartu</i> to Boron Toxicity Stress by Gul Sema Uyar, Anamika Pandey, Mehmet Hamurcu, Tomas Vyhnanek, Mustafa Harmankaya, Ali Topal, Sait Gezgin, Mohd. Kamran Khan

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Adaptive Immune Response to Model Antigens Is Impaired in Murine Leukocyte-Adhesion Deficiency-1 Revealing Elevated Activation Thresholds In Vivo by Thorsten Peters, Wilhelm Bloch, Oliver Pabst, Claudia Wickenhauser, Claudia Uthoff-Hachenberg, Susanne V. Schmidt, Georg Varga, Stephan Grabbe, Daniel Kess, Tsvetelina Oreshkova, Anca Sindrilaru, Klaus Addicks, Reinhold Förster, Werner Müller, Karin Scharffetter-Kochanek

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Comparison of brain activity metrics in Chinese and Russian students while perceiving information referencing self or others by Q. Si, J. Tian, V. A. Savostyanov, D. A. Lebedkin, A. V. Bocharov, A. N. Savostyanov

“…The developed software and hardware module is included in an integrated digital platform for conducting research in the field of systems biology and digital medicine.…”
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Exploring the epidemiological impact of attractive targeted sugar bait against malaria in combination with standard malaria control by Nima R. Moghaddas, Mohamed M. Traore, Gunter C. Müller, Joseph Wagman, Javan Chanda, Julian Entwistle, Christen M. Fornadel, Thomas S. Churcher

“…Nevertheless, the uncertainty in the relationship between the observed dyed fraction and the true bait-feeding rate, and the underlying biology of mosquito sugar-feeding means that the epidemiological benefit of this new possible intervention remains unclear.…”
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