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Structural bioinformatics for rational drug design
Published 2025-01-01“…A State of the Art lecture titled “structural bioinformatics technologies for rational drug design: from in silico to in vivo” was presented at the International Society on Thrombosis and Haemostasis (ISTH) Congress in 2024. …”
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Bioinformatics insights into mitochondrial and immune gene regulation in Alzheimer's disease
Published 2025-02-01Subjects: Get full text
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Characteristics and bioinformatics of peptides from natural and cultured sandfish (Holothuria scabra)
Published 2025-06-01“…This study aimed to investigate the characteristics and bioinformatics identification of peptides in sandfish (Holothuria scabra) protein hydrolysate from natural and cultured sources, with the hypothesis that different sources of sandfish and enzymatic treatments would result in distinct peptide profiles. …”
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Identification of hub genes and pathogenesis in Kawasaki disease based on bioinformatics analysis
Published 2024-04-01Subjects: “…bioinformatics…”
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Harnessing genomic and bioinformatic data to broaden understanding of leukaemia across continents
Published 2024-01-01“…Conclusion: This study successfully identified four genomic variants by harnessing a genomic and bioinformatic database, which are associated with leukemia and demonstrated variations in gene distribution and expression across different populations and tissues.…”
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Understanding integrative approach of translational bioinformatics on cardiovascular disease: Myocardial Ischemia
Published 2024-12-01“…This integrative approach demonstrates the potential of bioinformatics to improve cardiovascular health outcomes. …”
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Comprehensive Bioinformatics Method to Explore Immune-Related Genes in the Pathogenesis of Myocardial Infarction
Published 2025-01-01“…Objective: This study was aimed at exploring immune-related genes and their expression changes in myocardial infarction (MI) through comprehensive bioinformatics methods and validating these genes as potential diagnostic and therapeutic targets. …”
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Characterization of gene expression profiles in Alzheimer's disease and osteoarthritis: A bioinformatics study.
Published 2025-01-01“…This study explores the potential common molecular mechanisms between AD and OA through bioinformatics analysis, providing new insights for clinical treatment strategies.…”
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Investigation of catechin’s anti-inflammatory activity: A bioinformatics and molecular docking study
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Integrative bioinformatic approach reveals novel melatonin-related biomarkers for Alzheimer’s disease
Published 2025-02-01“…Hence, our research focused on the potential value of MLT-related genes (MRGs) in AD through bioinformatic analysis. Methods: First, the key cells in the single-cell dataset GSE138852 were screened out based on the proportion of annotated cells and Fisher’s test between the AD and control groups. …”
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Bioinformatics screening and clinical validation of CircRNA and related miRNA in male osteoporosis
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Unveiling the prognostic value of ARID3A in breast cancer through bioinformatic analysis
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Exploring the relationship between sepsis and Golgi apparatus dysfunction: bioinformatics insights and diagnostic marker discovery
Published 2025-02-01“…This study aims to explore the relationship between sepsis and the Golgi apparatus using bioinformatics, offering fresh insights into its diagnosis and treatment.MethodsTo explore the role of Golgi-related genes in sepsis, we analyzed mRNA expression profiles from the NCBI GEO database. …”
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Aberrant SNHG expression predicts poor prognosis in esophageal cancer using meta-analysis and bioinformatics analysis
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Utilizing bioinformatics and machine learning to identify CXCR4 gene-related therapeutic targets in diabetic foot ulcers
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