Genomic Analysis of miR-21-3p and Expression Pattern with Target Gene in Olive Flounder by Ara Jo, Hee-Eun Lee, Heui-Soo Kim

“…Using genomic and bioinformatic tools, evolutionary conservation of miR-21-3p was examined in various species, and expression pattern was analyzed in olive flounder. …”
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CD21low B cells reveal a unique glycosylation pattern with hypersialylation and hyperfucosylation by Peter Tobias Felixberger, Peter Tobias Felixberger, Geoffroy Andrieux, Andrea Maul-Pavicic, Andrea Maul-Pavicic, Sigune Goldacker, Sigune Goldacker, Ina Harder, Ina Harder, Sylvia Gutenberger, Sylvia Gutenberger, Jonathan J. M. Landry, Vladimir Benes, Till Fabian Jakob, Melanie Boerries, Melanie Boerries, Lars Nitschke, Reinhard Edmund Voll, Reinhard Edmund Voll, Klaus Warnatz, Klaus Warnatz, Baerbel Keller, Baerbel Keller

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The Utility of Perirenal Fat in Determining the Risk of Onset and Progression of Diabetic Kidney Disease by Hongtu Hu, Wei Liang, Zongwei Zhang, Zikang Liu, Fan Chu, Yan Bao, Jialu Ran, Guohua Ding

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Sequence Analysis of Hypothetical Proteins from 26695 to Identify Potential Virulence Factors by Ahmad Abu Turab Naqvi, Farah Anjum, Faez Iqbal Khan, Asimul Islam, Faizan Ahmad, Md. Imtaiyaz Hassan

“…This study involves extensive analysis of the HPs using an established pipeline which comprises various bioinformatics tools and databases to find out probable functions of the HPs and identification of virulence factors. …”
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Bioactive molecules from soybeans (Glycine max) with anti-type 2 diabetes activity: a systematic review by Adekunle Babajide Rowaiye, Lorretha Chinonye Emenyonu, Ezinne Janefrances Nwonu, Okiemute Ajiroghene Okpalefe, Joseph Akwoba Ogugua, Victor Oluwatoyin Akinseye, Gordon Chukwuma Ibeanu

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Mapping genomic regions affecting sensitivity to bovine respiratory disease on chromosome X using selective DNA pooling by Ehud Lipkin, Maria Giuseppina Strillacci, Miri Cohen-Zinder, Harel Eitam, Moran Yishay, Morris Soller, Carlotta Ferrari, Alessandro Bagnato, Ariel Shabtay

“…All regions overlapped or were very close to previously reported regions. Bioinformatics survey found candidate-by-location genes in these regions. …”
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Dexamethasone as an Analgesic Adjunct for Postcesarean Delivery Pain: A Randomized Controlled Trial by Jennifer E. Mehdiratta, Jennifer E. Dominguez, Yi-Ju Li, Remie Saab, Ashraf S. Habib, Terrence K. Allen

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Small open reading frames (sORFs): Driving big improvements in plant development and quality by Kui Dong, Chaofan Shan, Dongyu Wen, Zifan Cui, Jun Cao

“…With the advent of sophisticated technologies such as bioinformatics, ribosome profiling, and mass spectrometry, the investigation of sORFs has experienced a transformative shift and significant expansion. …”
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Identification of Houge type of X-linked syndromic mental retardation caused by CNKSR2 truncated variants by Si-Hua Chang, Jie-Yuan Jin, Yi-Qiao Hu, Run-Yan Wang, Rong Xiang, Xia Wang

“…Methods Two Chinese MRXSHG families were recruited, and their genetic causes were investigated using whole-exome sequencing (WES), Sanger sequencing, and bioinformatics analysis. To verify the impact of these variants, we used real-time PCR and minigenes consisting of exon 14, intron 14, and exon 15 from both the wild-type and the c.1658-3_1676del DNA sequences. …”
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Design and implementation of an asynchronous online course-based undergraduate research experience (CURE) in computational genomics. by Seema B Plaisier, Danielle O Alarid, Joelle A Denning, Sara E Brownell, Kenneth H Buetow, Katelyn M Cooper, Melissa A Wilson

“…We generated custom learning materials and leveraged remotely accessible computational tools to address 2 novel research questions over 2 iterations of the genomics CURE, one testing bioinformatics approaches and one mining cancer genomics data. …”
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Extraction, GC-MS analysis, cytotoxic, anti-inflammatory and anticancer potential of Cannabis sativa female flower; in vitro, in vivo and in silico by Waqas Safir, Arif Malik, Arif Malik, Haleema Saadia, Ayesha Zahid, Jinyao Li

“…The antiproliferative activities of the extract were determined on HeLa cells by using MTT, Crystal Violet, and Trypan Blue assays with an IC50 value suggesting 51%-77.6% lethality. The bioinformatics analysis of molecular docking proved significant ligand-protein interactions of CBD, THC, and humulene with cancer-associated proteins such as PD-1/PD-L1, TNF-α, and MMP-9. …”
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Investigation of Intestinal Microbes of Five Zokor Species Based on 16S rRNA Sequences by Yao Zou, Quan Zou, Hui Yang, Chongxuan Han

“…Here, we investigated the intestinal microbes of five zokor species (<i>Eospalax cansus</i>, <i>Eospalax rothschildi</i>, <i>Eospalax smithi</i>, <i>Myospalax aspalax</i>, and <i>Myospalax psilurus</i>) using 16S amplicon technology combined with bioinformatics. Microbial composition analysis showed similar intestinal microbes but different proportions among five zokor species, and their dominant bacteria corresponded to those of herbivores. …”
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Procedure Time and Students’ Perception Comparing Full Arch Digital Scans with Conventional Impressions: A Cross-Over Randomized Experimental Trial by Hayam A. Alfallaj, Mohammed A. Alsaloum, Sahr H. Altuwaijri, Omar S. Aldibasi, Lubna T. Alkadi

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AURKB affects the proliferation of clear cell renal cell carcinoma by regulating fatty acid metabolism by Yang Yang, Dan Li, Zhigang Liu, Kai Zhou, Wenxing Li, Yanqi Yang, Ruifang Sun, Yulong Li

“…Methods We performed bioinformatics analysis, CCK-8 assay, RNA sequencing, RT-PCR and Western blot to analyze the function and mechanism of AURKB in ccRCC. …”
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Identifying time patterns in Huntington’s disease trajectories using dynamic time warping-based clustering on multi-modal data by Alexia Giannoula, Audrey E. De Paepe, Ferran Sanz, Laura I. Furlong, Estela Camara

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Exploring damped and undamped frequencies in beam structures with viscoelastic supports using GFEM and state-space formulation by Gulnaz Kanwal, Hani Alahmadi, Rab Nawaz, Tayyab Nawaz

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Genomic Landscape Reveals Chromosomally-Mediated Antimicrobial Resistome and Virulome of a High-Risk International Clone II Acinetobacter baumannii AB073 from Thailand by Rattiya Cheewapat, Jadsadaporn Redkimned, Sirikran Lekuthai, Thawatchai Kitti, Kannipa Tasanapak, Aunchalee Thanwisai, Sutthirat Sitthisak, Thanet Sornda, Hathaichanok Impheng, Sudarat Onsurathum, Udomluk Leungtongkam, Supaporn Lamlertthon, Siriwat Kucharoenphaibul, Jintana Wongwigkarn, Pantira Singkum, Pattrarat Chanchaithong, Rapee Thummeepak

“…This study utilized integrative bioinformatics’ tools together with phenotypic assays to understand the whole-genome features of a carbapenem-resistant international clone II Acinetobacter baumannii AB073. …”
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Loss of SNHG4 Attenuated Spinal Nerve Ligation-Triggered Neuropathic Pain through Sponging miR-423-5p by Xia Pan, Cheng Shen, Yayi Huang, Long Wang, Zhongyuan Xia

“…Additionally, miR-423-5p was predicted as the target of SNHG4 by employing bioinformatics analysis. miR-423-5p has been reported to exert significantly poorer in several diseases. …”
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Identification of KIFC1 as an independent prognostic marker in renal clear cell carcinoma correlates with tumor proliferation and immune infiltration by Bin Du, Jia Wang, Jinping Zheng, Jing Huo, Pu Wang

“…We analyzed the prognostic value, associated signaling pathways, and regulatory mechanisms of KIFC1 in ccRCC through bioinformatics and proteomics. Concretely, both mRNA and protein expression levels of KIFC1 were dramatically upregulated. …”
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The Serum Expression of Selected miRNAs in Pulmonary Sarcoidosis with/without Löfgren’s Syndrome by Eva Novosadova, Alzbeta Chabronova, Vitezslav Kolek, Martin Petrek, Zdenka Navratilova

“…Patients with LS had dysregulated expressions of miR-21-5p and miR-340-5p compared to controls. Bioinformatics predicted consistently “Pathways in cancer” to be modulated by both altered profiles in patients with/without LS. …”
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