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    Antibacterial Potential of Honeybee Venom and <i>Monascus purpureus</i> Extracellular Metabolites Against Multidrug-Resistant Pathogenic Bacteria by Islam I. Teiba, Yasser S. A. Mazrou, Abeer H. Makhlouf, Yasser Nehela, Abdallah E. Mohamed, Ahmed M. Abbas, Islam Mamdouh, Emad H. El-Bilawy

    Published 2024-12-01
    “…The diversity in the chemical compositions of both extracts highlights their potential applications in pharmaceuticals, materials, and biochemistry fields. Collectively, these findings indicate that honeybee venom and the red dye from <i>M. purpureus</i> have promising antibacterial properties and warrant further investigation as potential alternatives to conventional antibiotics. …”
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    Effects of celastrol on the heart and liver galaninergic system expression in a mouse model of Western-type diet-induced obesity and metabolic dysfunction-associated steatotic live... by Nikolina Canová, Jana Šípková, Mahak Arora, Zuzana Pavlíková, Zuzana Pavlíková, Tomáš Kučera, Ondřej Šeda, Tijana Šopin, Tomáš Vacík, Ondřej Slanař

    Published 2025-02-01
    “…Moreover, the inhibitor of sterol regulatory element-binding protein 1/2 (SREBP1/2), fatostatin, was also tested to compare its influence on the galaninergic system with celastrol.ResultsThe study demonstrates that celastrol treatment was safe and led to a reduction in food and energy intake, body fat and liver weights, and MASLD-to-MASH progression and improved glucose tolerance, serum biochemistry markers, and hepatic lipid peroxidation in mice. …”
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