Evolution of SARS-CoV-2 spike trimers towards optimized heparan sulfate cross-linking and inter-chain mobility by Jurij Froese, Marco Mandalari, Monica Civera, Stefano Elli, Isabel Pagani, Elisa Vicenzi, Itzel Garcia-Monge, Daniele Di Iorio, Saskia Frank, Antonella Bisio, Dominik Lenhart, Rudolf Gruber, Edwin A. Yates, Ralf P. Richter, Marco Guerrini, Seraphine V. Wegner, Kay Grobe

Get full text

The Role of Dectin-1-Akt-RNF146 Pathway in β-Glucan Induced Immune Trained State of Monocyte in Sepsis by Guo C, Xu P, Luo W, Zhang J, Sun X, Hoang H, Ma D, Wu D, Zhong J, Miao C

“…Chenyue Guo,1,* Peiyao Xu,1,* Wenchen Luo,1,* Jinlin Zhang,1,* Xingfeng Sun,2 Harry Hoang,3 Duan Ma,4 Dehua Wu,5 Jing Zhong,1 Changhong Miao1 1Department of Anesthesiology, Zhongshan Hospital Fudan University, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai Key Laboratory of Perioperative Stress and Protection, Shanghai, People’s Republic of China; 2Department of Anesthesiology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, People’s Republic of China; 3Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland; 4Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education, Department of Biochemistry and Molecular Biology, Collaborative Innovation Center of Genetics and Development, Institute of Biomedical Sciences, School of Basic Medical Sciences, Fudan University, Shanghai, People’s Republic of China; 5Department of Anesthesiology, Shanghai Songjiang District Central Hospital, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Changhong Miao; Jing Zhong, Email ziteng1934@aliyun.com; jzhong12@fudan.edu.cnBackground: Sepsis is regarded as a dysregulated immune response to infections. …”
Get full text

Bone Formation by Sheep Stem Cells in an Ectopic Mouse Model: Comparison of Adipose and Bone Marrow Derived Cells and Identification of Donor-Derived Bone by Antibody Staining by Kristian Kjærgaard, Chris H. Dreyer, Nicholas Ditzel, Christina M. Andreasen, Li Chen, Søren P. Sheikh, Søren Overgaard, Ming Ding

Get full text

Patterns and predictors of mortality in a semi-urban population-based cohort in Sri Lanka: findings from the Ragama Health Study by Anuradhani Kasturiratne, Dileepa Senajith Ediriweera, Madunil Anuk Niriella, Hithanadura Janaka de Silva, Arunasalam Pathmeswaran, Shamila Thivanshi De Silva, Uthuru Beddage Thulani, Anuradha Supun Dassanayake, Arjuna Priyadarsin De Silva, Sureka Chackrewarthy, Udaya Ranawaka, Norihiro Kato, Ananda Rajitha Wickremasinghe

Get full text

Multilevel plasticity and altered glycosylation drive aggressiveness in hypoxic and glucose-deprived bladder cancer cells by Andreia Peixoto, Dylan Ferreira, Andreia Miranda, Marta Relvas-Santos, Rui Freitas, Tim S. Veth, Andreia Brandão, Eduardo Ferreira, Paula Paulo, Marta Cardoso, Cristiana Gaiteiro, Sofia Cotton, Janine Soares, Luís Lima, Filipe Teixeira, Rita Ferreira, Carlos Palmeira, Albert J.R. Heck, Maria José Oliveira, André M.N. Silva, Lúcio Lara Santos, José Alexandre Ferreira

Get full text

<i>Cannabis sativa</i> L. Extract Increases COX-1, COX-2 and TNF-α in the Hippocampus of Rats with Neuropathic Pain by Joanna Bartkowiak-Wieczorek, Małgorzata Jamka, Radosław Kujawski, Marcin Hołysz, Agnieszka Bienert, Kamila Czora-Poczwardowska, Michał Szulc, Przemysław Mikołajczak, Anna Bogacz, Anna-Maria Wizner, Karolina Wielgus, Ryszard Słomski, Edyta Mądry

Get full text

Prevalence and Determinants of Peripheral Neuropathy among Type 2 Adult Diabetes Patients Attending Jimma University Medical Center, Southwest Ethiopia, 2019, an Institutional-Base... by Daba Abdissa, Nigusse Hamba, Kumsa Kene, Deriba Abera Bedane, Guluma Etana, Dassalegn Muleta, Asfaw Gerbi

Get full text

Developing a Prototype Machine Learning Model to Predict Quality of Life Measures in People Living With HIV by Mercadal-Orfila G, Serrano López de las Hazas J, Riera-Jaume M, Herrera-Perez S

“…Gabriel Mercadal-Orfila,1,2 Joaquin Serrano López de las Hazas,3 Melchor Riera-Jaume,4 Salvador Herrera-Perez5 1Pharmacy Department, Hospital Mateu Orfila, Maón, Spain; 2Department of Biochemistry and Molecular Biology, Universitat de Les Illes Balears (UIB), Palma de Mallorca, Spain; 3Pharmacy Department, Hospital Universitario Son Llàtzer, Palma de Mallorca, Spain; 4Unidad de Enfermedades Infecciosas, Servicio de Medicina Interna, Hospital Universitario Son Espases, Palma de Mallorca, Spain; 5Facultad de Ciencias de la Salud, Universidad Internacional de Valencia, Valencia, EspañaCorrespondence: Salvador Herrera-Perez; Gabriel Mercadal-Orfila, Email salva.herrera@me.com; bielmercadal@gmail.comBackground: In the realm of Evidence-Based Medicine, introduced by Gordon Guyatt in the early 1990s, the integration of machine learning technologies marks a significant advancement towards more objective, evidence-driven healthcare. …”
Get full text

Anti-influenza effects of Aloe vera gel on MDCK cells: protective efficacy against ultraviolet-C exposure and analysis of biochemical characteristics and microbial activities by Rasha A. Al-Eisa, Rokayya Sami, Ruqaiah I. Bedaiwi, Roqayah H. Kadi, Suzan A. Abushal, Doaa Mahmoud Johari, Afnan M. Alnajeebi, Reham M. Algheshairy, Abeer A. Abu-Zaid, Sami A. Al-Dhumri

Get full text

Compatibility and antimicrobial activity of silver nanoparticles synthesized using Lycopersicon esculentum peels by Esraa Ali, Samah H. Abu-Hussien, Esraa Hesham, Shimaa Ahmed, Habiba Mostafa, Ahmed Gamal, Salwa M. El-Sayed, Bahaa Hemdan, Ashraf Bakry, Naglaa M. Ebeed, Hesham Elhariry, Ahmed Galal, Basma T. Abd-Elhalim

Get full text

Assessment of upper respiratory and gut bacterial microbiomes during COVID-19 infection in adults: potential aerodigestive transmission by Hafez Al-Momani, Andrew Nelson, Hadeel Al Balawi, Dua’a Al Balawi, Iman Aolymat, Ashraf I. Khasawneh, Hala Tabl, Ayman Alsheikh, AbdelRahman M. Zueter, Jeffrey Pearson, Christopher Ward

Get full text

Experimental Validation of Antiobesogenic and Osteoprotective Efficacy of Ginsenoside CK via Targeting Lipid and Atherosclerosis Pathways by Md. Niaj Morshed, Reshmi Akter, Imran Mahmud, Ah-Yeong Gwon, Jin Woo Jeang, Yeong-Geun Lee, Dae Won Park, Deok Chun Yang, Yeon Ju Kim, Se-Chan Kang

Get full text

Automation of quantum dot measurement analysis via explainable machine learning by Daniel Schug, Tyler J Kovach, M A Wolfe, Jared Benson, Sanghyeok Park, J P Dodson, J Corrigan, M A Eriksson, Justyna P Zwolak

Get full text

Discovery of anti-Ebola virus multi-target inhibitors from traditional Chinese medicine database using molecular screening, biophysical investigation, and binding free energy calcu... by Abbas Khan, Abrar Mohammad Sayaf, Anwar Mohammad, Fahad M. Alshabrmi, Tarek Benameur, Dong-Qing Wei, Kar Kheng Yeoh, Abdelali Agouni

Get full text

Annotated Checklist of Poroid Hymenochaetoid Fungi in Central Asia: Taxonomic Diversity, Ecological Roles, and Potential Distribution Patterns by Yusufjon Gafforov, Manzura Yarasheva, Xue-Wei Wang, Milena Rašeta, Yelena Rakhimova, Lyazzat Kyzmetova, Kanaim Bavlankulova, Sylvie Rapior, Jia-Jia Chen, Ewald Langer, Burkhon Munnavarov, Zafar Aslonov, Bobozoda Bakokhoja, Li-Wei Zhou

Get full text

Physical behaviours during pregnancy may alter the association of maternal insulin sensitivity with neonatal adiposity: a prospective pre-birth cohort of mother-child pairs by Piraveena Satkunanathan, Catherine Allard, Myriam Doyon, Patrice Perron, Luigi Bouchard, Marie-France Hivert, Tricia M. Peters

Get full text

Circulating levels of adiponectin and AdipoR expression in peripheral blood mononuclear cells are associated with lower respiratory tract Infection by Qian Wang, Xuemei Wang, Danning Xu, Mengjie Jiang, Yidan Gao, Lijuan Jiang, Meilian Liu, Haoneng Tang, Lingli Tang

Get full text

Crocin improves post-thaw quality, fertility-associated gene expression and fertilization potential of buffalo bull sperm by Amjad Riaz, Ghulam S. Khan, Muhammad Zahid Tahir, Muhammad Yasir Zahoor, Hifz-ul-Rahman Hifz-ul-Rahman

Get full text

Long-Term Effects of Adjuvant Intravitreal Treatment with Autologous Bone Marrow-Derived Lineage-Negative Cells in Retinitis Pigmentosa by Marta P. Wiącek, Wojciech Gosławski, Aleksandra Grabowicz, Anna Sobuś, Miłosz P. Kawa, Bartłomiej Baumert, Edyta Paczkowska, Sławomir Milczarek, Bogumiła Osękowska, Krzysztof Safranow, Alicja Zawiślak, Wojciech Lubiński, Bogusław Machaliński, Anna Machalińska

Get full text

Neuroprotective Effect of Taurine against Cell Death, Glial Changes, and Neuronal Loss in the Cerebellum of Rats Exposed to Chronic-Recurrent Neuroinflammation Induced by LPS by Samara P. Silva, Adriana M. Zago, Fabiano B. Carvalho, Lucas Germann, Gabriela de M. Colombo, Francine L. Rahmeier, Jessié M. Gutierres, Cristina R. Reschke, Margarete D. Bagatini, Charles E. Assmann, Marilda da C. Fernandes

Get full text