Impetus of US hospital leaders to invest in patient-reported outcome measures (PROMs): a qualitative study by Andrea L Pusic, Marilyn Heng, Danny Mou, Rachel C Sisodia, Meredith B Rosenthal, Barbara Bokhour, Christer Mjåset, Claire M Sokas, Azan Virji

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Enhanced proteomic profiling of human plasma‐derived extracellular vesicles through charge‐based fractionation to advance biomarker discovery potential by Xianyi Su, Getúlio Pereira de Oliveira Júnior, Anne‐Lise Marie, Michal Gregus, Amanda Figueroa‐Navedo, Ionita C. Ghiran, Alexander R. Ivanov

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Zinc Deficiency and the Recurrence of Clostridium difficile Infection after Fecal Microbiota Transplant: A Retrospective Cohort Study by Blake A. Niccum, Daniel J. Stein, Brian W. Behm, R. Ann Hays

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Association between early ondansetron use and the risk of sepsis in intensive care unit patients: a secondary data of the Medical Information Mart for Intensive Care IV database by Xuan Liu, Qiuye Kou, Enhe Liu

“…Objective This study planned to analyse the association between ondansetron use within 24 hours before intensive care unit (ICU) admission to within 48 hours after ICU admission and the risk of sepsis in ICU patients.Design A cohort study.Setting and participants Data of 65 366 participants in Medical Information Mart for Intensive Care IV from ICU in the Beth Israel Deaconess Medical Center.Primary and secondary outcome measures Sepsis was the primary outcome, which indicated patients with documented or suspected infection and acute change in total Sequential Organ Failure Assessment (SOFA) score ≥2 points. …”
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The impact of neuroscience education therapy, behavioral economics, and digital navigators on patient migraine treatment adherence to a mobile health application: a prospective pil... by Mia T. Minen, Erin K. Waire, John Torous, Jessica Fishman, Richard B. Lipton, Scott W. Powers

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The Effect of Prebiotics, Alone or as Part of Synbiotics, on Cardiometabolic Parameters in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized... by Elham Razmpoosh, Mala S. Sivanandy, Alan M. Ehrlich

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Unhealthy Phenotype as Indicated by Salivary Biomarkers: Glucose, Insulin, VEGF-A, and IL-12p70 in Obese Kuwaiti Adolescents by Mor-Li Hartman, J. Max Goodson, Ping Shi, Jorel Vargas, Tina Yaskell, Danielle Stephens, Maryann Cugini, Hatice Hasturk, Roula Barake, Osama Alsmadi, Sabiha Al-Mutawa, Jitendra Ariga, Pramod Soparkar, Jawad Behbehani, Kazem Behbehani, Francine Welty

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A multiresolution approach with method-informed statistical analysis for quantifying lymphatic pumping dynamics by Mohammad S. Razavi, Katarina J. Ruscic, Elizabeth G. Korn, Marla Marquez, Timothy T. Houle, Dhruv Singhal, Lance L. Munn, Timothy P. Padera

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Digital sleep phenotype and wrist actigraphy in individuals at clinical high risk for psychosis and people with schizophrenia spectrum disorders: a systematic review and meta-analy... by Andrea Cipriani, Edoardo Giuseppe Ostinelli, John Torous, Paolo Brambilla, Philip McGuire, Dominic Oliver, Rosario Aronica, Charlotte Austin

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Associations of the Need for Surgery in Emergency Department Patients with Small Bowel Obstructions by Daniel J. Berman, Alexander W. Mahler, Ryan C. Burke, Andrew E. Bennett, Nathan I. Shapiro, Leslie A. Bilello

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MAT2A inhibitor AG-270/S095033 in patients with advanced malignancies: a phase I trial by Mrinal Gounder, Melissa Johnson, Rebecca S. Heist, Geoffrey I. Shapiro, Sophie Postel-Vinay, Frederick H. Wilson, Elena Garralda, Gerburg Wulf, Caroline Almon, Salah Nabhan, Elia Aguado-Fraile, Peng He, Mathilde Romagnoli, Mohammad Hossain, Rohini Narayanaswamy, Amel Sadou-Dubourgnoux, Michael Cooper, Vasileios Askoxylakis, Howard A. Burris, Josep Tabernero

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Racial disparities in acute care utilization among individuals with myasthenia gravis by Cynthia Qi, Pushpa Narayanaswami, Ashley E. L. Anderson, Deborah Gelinas, Yuebing Li, Jeffrey T. Guptill, Dakshinamoorthy Amirthaganesan, Charlotte Ward, Rupesh Panchal, Amit Goyal, Glenn Phillips

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Effect of Low-Frequency Vibration on Muscle Response under Different Neurointact Conditions by Chaofei Zhang, Wenjun Wang, Dennis Anderson, Sishu Guan, Guofa Li, Hongyi Xiang, Hui Zhao, Bo Cheng

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Proteomic signature of HIV-associated subclinical left atrial remodeling and incident heart failure by Tess E. Peterson, Virginia S. Hahn, Ruin Moaddel, Min Zhu, Sabina A. Haberlen, Frank J. Palella, Michael Plankey, Joel S. Bader, Joao A. C. Lima, Robert E. Gerszten, Jerome I. Rotter, Stephen S. Rich, Susan R. Heckbert, Gregory D. Kirk, Damani A. Piggott, Luigi Ferrucci, Joseph B. Margolick, Todd T. Brown, Katherine C. Wu, Wendy S. Post

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Microglia modulate the cerebrovascular reactivity through ectonucleotidase CD39 by Zhongxiao Fu, Mallikarjunarao Ganesana, Philip Hwang, Xiao Tan, Melissa Marie Kinkaid, Yu-Yo Sun, Emily Bian, Aden Weybright, Hong-Ru Chen, Katia Sol-Church, Ukpong B. Eyo, Clare Pridans, Francisco J. Quintana, Simon C. Robson, Pankaj Kumar, B. Jill Venton, Anne Schaefer, Chia-Yi Kuan

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Vitamin D supplementation during intensive care unit stay is associated with improved outcomes in critically Ill patients with sepsis: a cohort study by Caifeng Li, Ke Zhao, Qian Ren, Lin Chen, Ying Zhang, Guolin Wang, Keliang Xie

“…However, whether vitamin D supplementation would improve their prognosis remains uncertain.MethodsWe conducted a retrospective cohort study using data from MIMIC-IV database, a publicly available database containing clinical information on patients admitted to the ICU at Beth Israel Deaconess Medical Center (BIDMC) from 2008 to 2019. Adult patients with sepsis were included in the analysis. …”
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Designing smartphone-based cognitive assessments for schizophrenia: Perspectives from a multisite study by Aishwarya Raje, Abhijit R. Rozatkar, Urvakhsh Meherwan Mehta, Ritu Shrivastava, Ameya Bondre, Manaal Amir Ahmad, Anshika Malviya, Yogendra Sen, Deepak Tugnawat, Anant Bhan, Tamonud Modak, Nabagata Das, Srilakshmi Nagendra, Erlend Lane, Juan Castillo, John A. Naslund, John Torous, Soumya Choudhary

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Investigation of geographic disparities and temporal changes of non-gestational diabetes-related emergency department visits in Florida: a retrospective ecological study by Md Marufuzzaman Khan, Agricola Odoi

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Development and validation of a novel risk-predicted model for early sepsis-associated acute kidney injury in critically ill patients: a retrospective cohort study by Bo Li, Kun Zhang, Cong-Cong Zhao, Zi-Han Nan, Yan-Ling Yin, Li-Xia Liu, Zhen-Jie Hu

“…External validation was performed using another single-centre intensive care unit (ICU) database.Setting Data for the development cohort were obtained from the MIMIC-IV 2.0 database, which is a large publicly available database that contains information on patients admitted to the ICUs of Beth Israel Deaconess Medical Center in Boston, Massachusetts, USA, from 2008 to 2019. …”
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Impact of empiric antibiotics on risk of Clostridioides difficile—a causal inference observational analysis by Matthew A. Pappas, Shoshana J. Herzig, Andrew D. Auerbach, Abhishek Deshpande, Eunice Blanchard, Michael B. Rothberg

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