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Impact of Methotrexate and 7‐Hydroxymethotrexate Exposure on Renal Toxicity in Pediatric Non‐Hodgkin Lymphoma
Published 2025-01-01“…After validation, the model estimated the peak concentration (Cmax) and area under the curve within the initial 48 h (AUC0‐48h) of the patients after drug administration by Bayesian feedback. The receiver operating characteristic (ROC) curves were generated to identify an exposure threshold associated with nephrotoxicity. …”
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1222
Global burden, trends, and disparities in kidney cancer attributable to smoking from 1990 to 2021
Published 2025-01-01“…Additionally, we projected age-standardized death and DALYs rates up to 2036 using Bayesian age-period-cohort (BAPC) models in R.ResultsGlobally, kidney cancer deaths attributable to smoking increased by 67.64%, from 9,673 in 1990 to 16,216 in 2021. …”
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1223
Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data
Published 2024-12-01“…Disproportionality analyses were conducted using several statistical methods, including reporting odds ratio (ROR), proportional reporting ratio (PRR), empirical Bayesian geometric mean (EBGM). Additionally, time-to-onset (TTO) analysis was employed to quantify the signals of the MPA-associated AEs.ResultsA comprehensive dataset comprising 21,035,995 AE reports was compiled. …”
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1224
Impacts of drought on respiratory mortality in the upper midwest United States: a population subgroup assessment
Published 2025-01-01“…We used the Evaporative Demand Drought Index categorized into three levels and analyzed it at two timescales: 6 months and 12 months. A Bayesian two-stage time-series modeling approach was applied to estimate the county-level and overall risk along with the 95% Credible Intervals (Cr). …”
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1225
Time-varying intensity of ventilatory inefficiency and mortality in patients with acute respiratory distress syndrome
Published 2025-01-01“…The primary outcome was 28-day mortality. Bayesian joint models were employed to estimate the strength of associations over time. …”
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1226
Larvicidal activity of Bacillus thuringiensis strains against Aedes aegypti and Culex quinquefasciatus mosquitoes
Published 2025-01-01“…All three Thailand strains contained cry1I and cry2A genes, and only JC691 harbored the cry32 gene. Bayesian inference and maximum likelihood phylogenetic analyses of cry32 indicated that the partial sequences of cry32 in JC691 from Thailand were distinct from those of other B. thuringiensis strains from different countries. …”
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1227
Direct antiglobulin test for the prediction of neonatal hyperbilirubinemia needing an intervention: a systematic review and diagnostic test accuracy meta-analysis
Published 2025-01-01“…Two reviewers screened the titles and abstracts blinded to each other. A Bayesian bivariate random-effects model was employed for the diagnostic test accuracy meta-analyses. …”
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1228
Metal mixtures exposure with risk of elevated serum neurofilament light chain concentrations in U.S. general adults, NHANES 2013–2014
Published 2025-01-01“…We employed a two-pronged approach, combining weighted quantile sum (WQS) and Bayesian kernel machine regression (BKMR) models, to examine the association between the multiple-metals effect and sNfL concentrations. …”
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1229
Global, regional and national burden of neuroblastoma and other peripheral nervous system tumors, 1990 to 2021 and predictions to 2035: visualizing epidemiological characteristics...
Published 2025-02-01“…In addition, the average annual percentage change (AAPC) and Age-Period-Cohort (APC) model were used to evaluate the trend of disease burden, while the global burden of disease to 2035 was predicted by Bayesian Age-Period-Cohort (BAPC) model. Findings: This study reported the disease burden of neuroblastoma and other peripheral nervous system tumors in GBD 2021 database for the first time. …”
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1230
Effect of comorbidity classes on survival of patients with gastrointestinal tract cancer
Published 2025-02-01“…Additionally, the performance of different simple multimorbidity measures were compared using the Bayesian information criterion (BIC), ROC curves and C-index. …”
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1231
High-resolution spatiotemporal analysis of chikungunya epidemics between 2019 and 2020 in Salvador, Brazil: a municipality-level transmission dynamics studyResearch in context
Published 2025-03-01“…We used SaTScan software to identify spatiotemporal clusters and assessed how census tract characteristics (socioeconomic, environmental, and prior chikungunya occurrence) influenced chikungunya incidence through a Bayesian spatial model using Integrated Laplace Approximation (INLA). …”
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1232
Exploring the relationships between self-efficacy, self-care, and glycaemic control in primary care diabetes management
Published 2024-12-01“…Network analysis in R software examined relationships between self-efficacy and self-care dimensions across glycaemic control subgroups using a Gaussian graphical model with the extended Bayesian information criterion. Results: Half the PWDs (50.7%) had suboptimal glycaemic control. …”
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1233
Water cycle modelling strengthened by probabilistic integration of field data for groundwater management of a quite unknown tropical volcanic hydrosystem
Published 2023-01-01“…Multiple Markov chains allow a better exploration of the parameter values. The Bayesian approach provides the best water cycle simulation with a parameter uncertainty analysis, improving the accuracy and representation of the water cycle appropriate for previously unknown hydrosystems.…”
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1234
Global assessment of leukemia care quality: insights from the quality of care index (QCI) from 1990 to 2021Research in context
Published 2025-01-01“…Then we employed the bayesian age-period-cohort (BAPC) model to predict future QCI trends. …”
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1235
Effects of population aging on quality of life and disease burden: a population-based study
Published 2025-01-01“…The HALE and DALY projections were generated using both the Bayesian age-period-cohort models and the population prediction models. …”
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1236
Genotyping-by-sequencing derived SNP markers reveal genetic diversity and population structure of Dactylis glomerata germplasm
Published 2025-02-01“…Population structure analysis using Bayesian clustering, PCoA and UPGMA dendrograms divided the accessions into three distinct clusters, with cluster membership largely reflecting geographical origins, and dry biomass content. …”
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1237
Comparison of Therapeutic Effects of Different Rehabilitation Methods on Patients Undergoing Total Knee Arthroplasty: A Network Meta‐Analysis of Randomized Controlled Trials
Published 2025-02-01“…And use the range of motion (ROM), visual analog scale (VAS), Western Ontario and McMaster Universities osteoarthritis index (WOMAC) as the outcome measure to evaluate the effectiveness of various interventions. A Bayesian network meta‐analysis (NMA) was carried out for calculating standardized mean difference (SMD) and the surface under cumulative ranking curve (SUCRA) of improvement of knee joint function after TKA by different rehabilitation methods. …”
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1238
Long-term effects of post-earthquake landslides on vegetation ecosystem net carbon
Published 2025-02-01“…Using landslide inventories and satellite data, we applied the Seasonal Autoregressive Integrated Moving Average Model (SARIMA) model and Bayesian change-point detection to examine long-term effects of post-earthquake landslides on vegetation ecosystem net carbon uptake (ENCU). …”
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1239
Outbreak of carbapenem resistant Klebsiella pneumoniae in a neurorehabilitation unit: Genomic epidemiology reveals complex transmission pattern in a tertiary care hospital
Published 2025-03-01“…The most likely transmission networks of KPC-Kp were reconstructed with Bayesian discrete-time stochastic models. Results: Nineteen patients were colonized by KPC-Kp. …”
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Time to first antenatal care visit and its predictors among women in Kenya: Weibull gamma shared frailty model (based on the recent 2022 KDHS data)
Published 2025-01-01“…Shared frailty survival models were used to account for the hierarchical data structure and unobserved heterogeneity, with the Weibull gamma model identified as the best fit based on Information Criteria (AIC), and Bayesian Information Criteria (BIC). Variables with p < 0.2 entered multivariable analysis, and results were reported as Adjusted Hazard Ratios (AHR) with 95% Confidence Intervals (CI) using the Weibull gamma model. …”
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