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我国华南中麝鼩分子系统地理学分析
Published 2024-05-01“…为了明确我国华南中麝鼩的分子系统地理格局,为其分类学提供进一步分子生物学证据,测定了我国贵州华南中麝鼩20个样本的<italic>Cyt b</italic>基因序列,并结合GenBank下载的19个华南中麝鼩<italic>Cyt b</italic>基因序列进行一并分析。结果表明:系统发生树首先分成3个大的进化支,即华南中麝鼩华南亚种(<italic>C.r.rapax</italic>)进化支、西南中麝鼩(<italic>C.vorax</italic>)进化支、华南中麝鼩台中亚种(<italic>C.rapax kurodai</italic>)进化支。…”
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3022
Integrated analysis of cell cycle and p53 signaling pathways related genes in breast, colorectal, lung, and pancreatic cancers: implications for prognosis and drug sensitivity for...
Published 2024-12-01“…Survival analysis was conducted using TCGA data by GEPIA2 and LASSO, and drug sensitivity was analyzed with the GSCA drug bank database, highlighting potential therapeutic targets. …”
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3023
Characterizing a complex buildup in the Pearl River Mouth Basin of the northern South China Sea: an interplay of carbonates and igneous rocks
Published 2025-01-01“…The evolution of the buildup is divided into three stages: (1) volcanic eruptions and carbonates development, (2) overflowing magma and reef shoal deposits, and (3) reef-bank deposition accompanied by igneous intrusion. …”
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Polygenic prediction of human longevity on the supposition of pervasive pleiotropy
Published 2024-08-01“…We assessed the predictive performance of our model for distinguishing the enrichment of exceptional longevity among long-lived individuals in two replication cohorts (the Scripps Wellderly cohort and the Medical Genome Reference Bank (MRGB)) and showed that the median lifespan in the highest decile of our composite prognostic index is up to 4.8 years longer. …”
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Immunoinformatics Approach for Multiepitope Vaccine Prediction from H, M, F, and N Proteins of Peste des Petits Ruminants Virus
Published 2019-01-01“…The sequences of the immunogenic proteins were retrieved from GenBank of the National Center for Biotechnology Information (NCBI). …”
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Experimental prosopis management practices and grassland restoration in three Eastern African countries
Published 2023-07-01“…Compared to the effect of prosopis removal, the effect of restoration interventions on vegetation composition was small, indicating that most species re-established from the soil seed bank. The results show that it is possible to restore land previously invaded by prosopis. …”
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Investigating the Impact of Order Flow Imbalance and Information Asymmetry on Treasury Bill Price Changes
Published 2024-06-01“…Considering the price impact of orders and the significance of the secondary market for Islamic treasury bills as a pivotal tool in the central bank's monetary policy and government financing, this study aims to investigate the price effects of order flow on the price fluctuations of Islamic treasury bills in the market. …”
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蚊虫细胞色素P450 基因系列研究
Published 2001-01-01“…报告中山医科大学寄生虫学教研室医学昆虫学室近5 年来有关蚊虫细胞色素P450 基因(CYP450)系列研究 结果, 包括:①通过简并引物PCR 分别从致倦库蚊、白纹伊蚊及中华按蚊中获得3 个、2 个、2 个CYP4 家族成员基因片段;通 过简并引物PCR 及RT-PCR 从白纹伊蚊中获得16 个CYP6 家族成员基因片段;②利用cDNA 末端快速扩增(RACE)法获得 了白纹伊蚊CYP 6 家族3 个新的全长cDNA 序列及7 个超过其全长一半以上的cDNA 序列。GenBank accession number 分别 为AF283836-AF283838(全长cDNA 序列)和AF284782-AF284783(非全长cDNA 序列), 被国际P450 命名委员会正式命名为 CYP 6N3v1-v3(全长cDNA 序列)和CYP 6N3v4 、CYP 6N4v1-v6, 并证实这些新基因同时存在于白纹伊蚊溴氰菊酯抗性株及 敏感株中;③运用基因步移方法从白纹伊蚊溴氰菊酯抗性株中扩增出CYP 6N3 上游3 076 bp 调控序列;④对白纹伊蚊 CYP 6N3、CYP 6N4 非翻译区序列功能分析显示:昆虫CYP450 与其它真核m RNA 翻译起始及终止机制相似, 但具有多态性 的特点;⑤对白纹伊蚊CYP 6N3 上游启动子区序列特征与功能分析显示:蚊虫中CYP450 转录起始存在着复杂性;⑥证实蚊 虫中CYP 6 存在多样性, 并分析讨论了此种多样性形成的可能机制;⑦分析讨论了蚊虫细胞色素P450 CYP 6 家族分子进化 机制;⑧阐明了下一步研究的目标。…”
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Optimization, characterization and biosafety of oregano, rosemary and mint oil mixture against Penicillium digitatum in citrus using L-optimal mixture design
Published 2025-01-01“…It was deposited in GenBank with gene accession number PP930644 and deposited in MIRCEN culture collection as EMCC 358874. …”
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3032
Loan Monitoring Costs and Loan Payment in SACCOs: A Case Study of Mitooma People's SACCO in Mitooma Town Council Mitooma District.
Published 2024“…From the study findings on challenges faced by loan officers in monitoring loans in SACCOs, respondents revealed that poor transport infrastructure to the rural places, clients who provide wrong information to the bank, multiple borrowing by the clients in different borrowing institutions, social factors showing a weak influence on loan default, lack of liquidity monitoring system, inadequate managerial competencies and political interference and huge microfinance losses are caused by outright loan default were some of the challenges faced by loan officers in monitoring loans in SACCOs.…”
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3033
Investigating the cost of mechanized unpaved road maintenance operations in Uganda
Published 2025“…The Uganda National Roads Authority (UNRA) unpaved road maintenance costs were calculated as an average of 34,987,122.9Ugx/km (9,165USD/km) while the World Bank ROCKS database provided a comparable figure of 7,971USD/km (30,553,440.83Ugx/km). …”
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3037
The Prevalence of Star-forming Clumps as a Function of Environmental Overdensity in Local Galaxies
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3038
In silico development of a multi-epitope-based vaccine against Burkholderia cepacia complex using reverse vaccinology
Published 2025-01-01“…BackgroundMultidrug-resistant Burkholderia cenocepacia and Burkholderia multivorans have emerged as significant pathogens, particularly in patients with cystic fibrosis (CF) and chronic granulomatous disease (CGD).ObjectiveGiven the absence of approved vaccines, this study aimed to identify potential vaccine candidates against these pathogens.MethodsThe complete genomes of B. cenocepacia and B. multivorans were retrieved from the GenBank. Surface-exposed proteins that were antigenic, non-allergenic, and non-homologous to human proteins were selected for further analysis. …”
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Bio-active composition, antibacterial activity and molecular docking studies of Salicia nitida (Benth.) root extracts
Published 2024-12-01“…A computational analysis was conducted to analyze the potential antibacterial bioactive component, Butylated hydroxytolene (Compound Identification number CID: 31404) and 5-Eicosene (Compound Identification number (CID): 5364600), identified from Gas Chromatography-Mass Spectrophotometry (GC-MS) analysis, against class A beta-lactamase enzyme (Protein Data Bank (PDB): 3BLM) to identify its inhibition potentials. …”
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Genome-Wide Genomic Analysis and Evolutionary Insights into Bovine Coronavirus Strains in Southwest China
Published 2024-12-01“…To elucidate the genetic evolution and characterisation of the prevalent strains, the results of BCoV sequences were compared in GenBank, with a focus on genetic evolution, mutation, and recombination patterns. …”
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