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  1. 2701

    Identification of dequalinium as a potent inhibitor of human organic cation transporter 2 by machine learning based QSAR model by Fumihiro Yamane, Kenji Ikemura, Masayoshi Kondo, Manami Ueno, Masahiro Okuda

    Published 2025-01-01
    “…Using our QSAR model, we identified 162 candidate hOCT2 inhibitors among the FDA-approved drugs registered in the DrugBank database. After manual selection and in vitro assays, we found that dequalinium, a quaternary ammonium cation antimicrobial agent, is a potent hOCT2 inhibitor (IC50 = 88.16 ± 7.14 nM). …”
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    Post-Pandemic Inflation Dynamics: a Comparative Study of the Fiscal Theory in the Czech Republic and France by Makovský, Petr, Descubes, Irena, Hřebík, František

    Published 2024-12-01
    “…Results: Utilizing empirical survey data primarily from the Czech Republic and France, sourced from the Czech Statistical Office, the Czech National Bank, Banque de France, and INSEE, this study engages with the Fiscal Theory of Prices to elucidate these phenomena. …”
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  6. 2706

    Analysis of the Complete Genomes of Enterovirus 71 Subtypes in China by Lei Wang, Yuzhu Dai, Jun Cheng, Changgui Sun, Yu Chen, Dawei Cui

    Published 2021-01-01
    “…Here, the complete genomes of EV-A71 from China between 1998 and 2019 were downloaded from GenBank. The phylogenetic trees were developed by MEGA7.0 software, and the complete genetic epidemiological characteristics and amino acid mutations of EV-A71 from China were also analysed. …”
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  7. 2707

    Research on credit card transaction security supervision based on PU learning by Renfeng CHEN, Hongbin ZHU

    Published 2023-06-01
    “…The complex and ever-evolving nature of credit card cash out methods and the emergence of various forms of fake transactions present challenges in obtaining accurate transaction information during customer interactions.In order to develop an accurate supervision method for detecting fake credit card transactions, a PU (positive-unlabeled learning) based security identification model for single credit card transactions was established.It was based on long-term transaction label data from cashed-up accounts in commercial banks’ credit card systems.A Spy mechanism was introduced into sample data annotation by selecting million positive samples of highly reliable cash-out transactions and 1.3 million samples of transactions to be labeled, and using a learner to predict the result distribution and label negative samples of non-cash-out transactions that were difficult to identify, resulting in 1.2 million relatively reliable negative sample labels.Based on these samples, 120 candidate variables were constructed, including credit card customer attributes, quota usage, and transaction preference characteristics.After importance screening of variables, nearly 50 candidate variables were selected.The XGBoost binary classification algorithm was used for model development and prediction.The results show that the proposed model achieve an identification accuracy of 94.20%, with a group stability index (PSI) of 0.10%, indicating that the single credit card transaction security identification model based on PU learning can effectively monitor fake transactions.This study improves the model discrimination performance of machine learning binary classification algorithm in scenarios where high-precision sample label data is difficult to obtain, providing a new method for transaction security monitoring in commercial bank credit card systems.…”
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    林麝<i>FASN</i>基因CDS区克隆及序列分析 by 谌颖莲 竭 航 赵贵军 封孝兰 张承露 吴佳勇 曾德军

    Published 2022-01-01
    “…获取了林麝<i>FASN</i>基因的mRNA序列(GenBank ID:MW570770),其具有一定的物种保守性,筛选出16个关键位点,其中第307、602、657和1 334位氨基酸能够改变蛋白羟基活性,预测出10个蛋白磷酸化位点,miR-1307-5p和miR-669与3’-UTR亲和能力较强。…”
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  12. 2712

    Dynamique des savoirs et des échanges d’un produit de collecte en territoire transfrontalier by Laval Pauline

    Published 2012-11-01
    “…The final discussion approaches the problem of tenure of lands on each bank of the river Oyapock. The situation is blocked and that hinders the conditions of collection fruits, and slows down the improvement of collected volumes. …”
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    Signatures of Transient Overvoltages in Low Voltage Power Systems in Tea Factories and Their Implications on Insulation Deterioration and Allied Power Quality Issues by Earl A. R. L. Pannila, Mahesh Edirisinghe

    Published 2021-01-01
    “…Thus, this study mainly investigates the impact of switching transients generated by electromechanical machines in industrial power systems on insulation deterioration while taking transient overvoltages due to capacitor bank switching also to support. Transients with a high rate of rise are likely to catalyze the degradation of the insulation quality and break down the insulating material through ionization. …”
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    The Increasing Financial Impact of Chronic Kidney Disease in Australia by Patrick S. Tucker, Michael I. Kingsley, R. Hugh Morton, Aaron T. Scanlan, Vincent J. Dalbo

    Published 2014-01-01
    “…Data published by Australia and New Zealand Dialysis and Transplant Registry, Australian Institute of Health and Welfare, and World Bank were used to compare CKD-, RRT-, and CVD-related expenditure and prevalence rates. …”
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  20. 2720

    Impact of Human Capital Development on Economic Growth in Uganda. by Nuwagaba, Christopher

    Published 2024
    “…The primary objective of this study was to examine the relationship between human capital development and economic growth from 2012 to 2022, utilizing secondary time series data sourced from the World Bank and World Development Indicators. Human capital plays a crucial role in enabling countries to enhance their economic performance and improve the well-being of their citizens. …”
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