Functional Remediation Improves Serum BDNF and TrkB Levels in Euthymic Patients with Bipolar Disorder: A Randomized Trial Study by Li R, Li J, Ji SS, Li D, Chu L, Zhang J, Sun X, Luo X, Zhang Y

“…Meanwhile, we collected blood samples (10 milliliters) from all participants for determination of serum BDNF/ TrkB levels both at baseline and week 12. After baseline assessment, all participants received FR or TAU treatments, respectively.Results: Our results showed significant decreasing in HDRS-17 and YMRS scores, increasing in serum BDNF and TrkB levels in both groups over 12 weeks (all p’s< 0.05). …”
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Mapping C. difficile TcdB interactions with host cell-surface and intracellular factors using proximity-dependent biotinylation labeling by Jennifer S. Ward, Karl J. Schreiber, John Tam, Ji-Young Youn, Roman A. Melnyk

“…Here, we used BioID to interrogate proximal interactors of the multi-domain Clostridioides difficile TcdB toxin. Expressed fusions of TurboID to different fragments of TcdB identified several high-confidence proteins in the cytosol, including members of the Rho GTPase signaling network and the actin cytoskeletal network. …”
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Simultaneous Quantification of Aspirin, Its Metabolite Salicylic Acid, and Salvianolic Acid B in Human Plasma Using UPLC-MS/MS by Weiyi Cao, Hezhi Yao, Zhenzhen Qian, Yi Wu, Shuge Wang, Rui Li, Rui Gao

“…Salvianolic acid B is the main active ingredient in salvianolate injection, which is produced by extracting danshen, the most commonly used Chinese herbal medicine for cardiovascular treatment. …”
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Aurora B inhibition induces hyper-polyploidy and loss of long-term proliferative potential in RB and p53 defective cells by Shivam Vora, Saptarshi Chatterjee, Ariel Andrew, Ramyashree Prasanna Kumar, Martina Proctor, Zhen Zeng, Rituparna Bhatt, Deborah Nazareth, Madushan Fernando, Mathew J. K. Jones, Yaowu He, John D. Hooper, Nigel A. J. McMillan, Jelena Urosevic, Jamal Saeh, Jon Travers, Daniela Cimini, Jing Chen, Brian Gabrielli

“…Model for AURKBi driven hyper-polyploid cells formation and fate. Aurora B inhibitor (AURKBi) treatment of RB+p53 defective cells efficiently promotes failed cell division. …”
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Clinical and Radiological Outcome of Anterior only Stabilization for AO Type B And C Subaxial Cervical Spine Injury: An Observational Study by Ram Sharma Subedi, Gaurav Raj Dhakal, Bhadra Hamal, Kabita Devi Baral, Badri Rijal, Mahesh Karmacharya, Prem Kumar Sah

“… Introduction: AO type B and C subaxial cervical spine injuries are highly unstable and require surgical fixation for the stabilization. …”
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B16黑色素瘤NK免疫耐受变异群在体外的产生及其意义

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Pharmacological Effects of JTT-551, a Novel Protein Tyrosine Phosphatase 1B Inhibitor, in Diet-Induced Obesity Mice by Makoto Ito, Sumiaki Fukuda, Shohei Sakata, Hisayo Morinaga, Takeshi Ohta

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Electroacupuncture Improves Baroreflex and γ-Aminobutyric Acid Type B Receptor-Mediated Responses in the Nucleus Tractus Solitarii of Hypertensive Rats by Qi Zhang, Ying-Ying Tan, Xiao-hua Liu, Fan-Rong Yao, Dong-Yuan Cao

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Time-Qualified Patterns of Variation of PPARγ, DNMT1, and DNMT3B Expression in Pancreatic Cancer Cell Lines by Valerio Pazienza, Francesca Tavano, Massimo Francavilla, Andrea Fontana, Fabio Pellegrini, Giorgia Benegiamo, Vincenzo Corbo, Fabio Francesco di Mola, Pierluigi Di Sebastiano, Angelo Andriulli, Gianluigi Mazzoccoli

“…We investigated the time-related patterns of PPARG, DNMT1, and DNMT3B expression monitoring their mRNA levels by qRT-PCR at different time points over a 28-hour span in BxPC-3, CFPAC-1, PANC-1, and MIAPaCa-2 PC cells after synchronization with serum shock. …”
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C－erbB－2表达对乳腺浸润性导管癌预后的预测

“…应用单克隆抗体Ｃ－ｅｒｂＢ－２肿瘤蛋白及免疫组化（ＬＳＡＢ）法，对８４例乳腺浸润性导管癌作Ｃ－ｅｒｂＢ－２癌基因蛋白产物表达（简称Ｃ－ｅｒｂＢ－２表达）检测并与随诊资料进行比较分析，结果（１）Ｃ－ｅｒｂＢ－２在本组病例的表达率为５５．９％（４７／８４）。…”
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Scrutinizing the untapped potential of emerging ABSe3 (A = Ca, Ba; B = Zr, Hf) chalcogenide perovskites solar cells by Dhineshkumar Srinivasan, Aruna-Devi Rasu Chettiar, Eupsy Navis Vincent Mercy, Latha Marasamy

“…Hence, we have investigated the potential of Se-based absorbers with device structure FTO/TiO2/ABSe3 (A = Ca, Ba; B = Zr, Hf)/NiO/Au using SCAPS-1D. We analyzed the critical parameters impacting each layer of the solar cell. …”
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Rancang Bangun Sistem Kontrol dan Monitoring Data Turbin Angin Berbasis Website Menggunakan Raspberry Pi 3B+ by Meiki Eru Putra, Zulkifli Amin, Islahuddin Islahuddin, Sanny Ardhy

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A Case of Polymyxin b-Immobilized Fiber Column Treatment for Rapidly Progressive Interstitial Pneumonia Associated with Clinically Amyopathic Dermatomyositis by Oh Sasaki, Makoto Dohi, Hiroaki Harada, Mitsuru Imamura, Yumi Tsuchida, Kensuke Yamaguchi, Toshihiko Komai, Kazuhiko Yamamoto

“…After polymyxin b-immobilized fiber column treatment, the areas of pulmonary shadows drastically decreased. …”
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Seroprevalences of Hepatitis B Virus and Hepatitis C Virus among Participants of an Asian Health Fair in the Lower Mainland, British Columbia by Stephen Ip, Jo-Ann Ford, Kirby Lau, Vladimir Marquez, Marisa Guan, Carolyn Klassen, Jessica Chan, WC Peter Kwan, Mel Krajden, Eric M Yoshida

“…BACKGROUND: The seroprevalences of hepatitis B virus (HBV) and hepatitis C virus (HCV) are 0.4% and 0.8%, respectively, in Canada, but varying rates have been reported in different populations.…”
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Stability and bifurcation of a time-varying delay predator–prey model with Allee effect, prey refuge and B-D function by Qiang Zhou, Xin-You Meng

“…This paper mainly considers a time-varying delay predator–prey model with Allee effect, prey refuge and B-D functional response. First, the positivity and boundedness of solutions of such model without delay are proved. …”
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Proteomic Analysis of the Murine Liver Response to Oral Exposure to Aflatoxin B1 and Ochratoxin A: The Protective Role to Bioactive Compounds by Silvia Trombetti, Alessandra Cimbalo, Michela Grosso, Pilar Vila-Donat, Jordi Mañes, Lara Manyes

“…Aflatoxin B1 (AFB1) and Ochratoxin A (OTA) are considered the most important mycotoxins in terms of food safety. …”
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Sex Differences in Spontaneous Degranulation Activity of Intrahepatic Natural Killer Cells during Chronic Hepatitis B: Association with Estradiol Levels by Zuzana Macek Jilkova, Thomas Decaens, Alice Marlu, Hélène Marche, Evelyne Jouvin-Marche, Patrice N. Marche

“…Major sex differences are observed in the prevalence, intensity, and severity of hepatitis B virus (HBV) infection. Here, we investigated degranulation activity of circulating and intrahepatic natural killer (NK) cells from HBV and HCV chronically infected patients before any treatment (n=125). …”
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Dietary Nannochloropsis oculata ameliorates lead acetate induced reproductive toxicity in Barki rams: NF-κB and cytokines pathways by Doaa H. Elsayed, Sameer A. Nagadi, Heba M.A. Abdelrazek, Ahmed. S. El‑Hawy, Moharram F. El-Bassiony, Seham A. Helmy, Yasmina K. Mahmoud, Ibrahim E. Helal, Shady T. Hassan

“…Testicular oxidant/antioxidant markers, cytokines, gene expression of interleukin-6 (IL-6) and nuclear factor Kappa B (NF-κB) were estimated. Alga-treated rams revealed significant upgrades in semen criteria, serum testosterone and reduced glutathione (GSH); meanwhile, downregulation in malondialdehyde (MDA), IL-4, IL-2 as well as gene expressions of IL-6 and NF-κB as compared to other treated groups. …”
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Tumor-Derived Exosomal miR-29b Reduces Angiogenesis in Pancreatic Cancer by Silencing ROBO1 and SRGAP2 by Lihua Wang, Lei Yang, Tingting Zhuang, Xiuqing Shi

“…Background. Exosomal miR-29b reportedly plays a role during cancer metastasis. …”
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Introducing Single Dose Liposomal Amphotericin B for the Treatment of Visceral Leishmaniasis in Rural Bangladesh: Feasibility and Acceptance to Patients and Health Staff by Eva-Maria Maintz, Mahbub Hassan, M. Mamun Huda, Debashis Ghosh, Md. Shakhawat Hossain, Abdul Alim, Axel Kroeger, Byron Arana, Dinesh Mondal

“…For the treatment of visceral leishmaniasis in Bangladesh, single dose liposomal amphotericin B (ambisome) is supposed to be the safest and most effective treatment. …”
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