Limited Diagnostic Value of miRNAs in Early Trauma-Induced Liver Injury: Only miRNA-122 Emerges as a Late-Phase Marker by Jason-Alexander Hörauf, Amit Singh, Maika Voth, Hamed Moheimani, Cora Rebecca Schindler, Borna Relja, Liudmila Leppik, Ingo Marzi, Dirk Henrich

“…This study investigates whether specific liver-related microRNAs (miRNAs) are released into the circulation in trauma patients with liver injury and whether they can indicate liver damage in the early phase after major trauma. <b>Methods</b>: A retrospective analysis of prospectively collected data and blood samples from 26 trauma patients was conducted. …”
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Circumscribed choroidal hemangioma: clinical course and treatment by A.F. Brovkina, A.S. Stoyukhina, I.V. Musatkina

“…<p> <b>A.F.&nbsp;Brovkina¹, A.S.&nbsp;Stoyukhina², I.V.…”
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A Randomized, Placebo-Controlled, Single-Center, Crossover Study to Evaluate the Effects of Pre-Meal Whey Protein Microgel on Post-Prandial Glucometabolic and Amino Acid Response i... by Ian J Neeland, Luiz H de Gregório, Roberto Zagury, Bo Ahrén, Joel Neutel, Christian Darimont, John Corthesy, Yohan Grzywinski, Emilie Perrin, Maximilian von Eynatten, Odd Erik Johansen

“…No adverse events were ascribed to consuming WPM. <b>Conclusions</b>: A 125 mL pre-meal drink containing just 10 g WPM before a mixed meal reduced PPG and increased insulin, GLP-1, and BCAAs. …”
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Early Prediction of Abdominal Aortic Aneurysm Rupture Risk Using Numerical Biomechanical Analysis by Kristina Grassl, Thomas C. Gasser, Florian K. Enzmann, Alexandra Gratl, Josef Klocker, David Wippel, David C. Walcher, Elke R. Gizewski, Sabine H. Wipper

“…<b>Objective</b>: We aimed to predict patient-specific rupture risks and growth behaviors in abdominal aortic aneurysm (AAA) patients using biomechanical evaluation with finite element analysis to establish an additional AAA repair threshold besides diameter and sex. <b>Methods</b>: A total of 1219 patients treated between 2005 and 2024 (conservative and repaired AAAs) were screened for a pseudo-prospective single-center study. …”
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Polo-like Kinase 1 Expression as a Biomarker in Colorectal Cancer: A Retrospective Two-Center Study by Lana Jajac Brucic, Vesna Bisof, Majana Soce, Marko Skelin, Ivan Krecak, Andjela Nadinic, Branka Vrbicic, Zivana Puljiz, Suzana Hancic, Slavko Gasparov

“…The aim of this study was to assess PLK-1 expression considering the age of the patients and its effects on overall survival (OS) and progression-free survival (PFS). <b>Results</b>: A total of 146 patients with metastatic colorectal cancer (mCRC) were included in this retrospective two-center study. …”
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Diffusion Tensor Imaging as Neurologic Predictor in Patients Affected by Traumatic Brain Injury: Scoping Review by Federica Paolini, Salvatore Marrone, Gianluca Scalia, Rosa Maria Gerardi, Lapo Bonosi, Umberto Emanuele Benigno, Sofia Musso, Alba Scerrati, Domenico Gerardo Iacopino, Francesco Signorelli, Rosario Maugeri, Massimiliano Visocchi

“…What is the ongoing role of DTI in detecting brain alterations and predicting neurological outcomes in patients with moderate to severe traumatic brain injury and/or diffuse axonal injury? <b>Methods</b>: A scoping review of the PubMed, Scopus, EMBASE, and Cochrane databases was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. …”
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The Impact of Acute Aerobic Exercise on General and Food-Related Inhibitory Function Among Young Adults with Obesity: An Event-Related Potential (ERP) Study by Chun Xie, Tao Huang, Yingying Wang, Peisi Wang, Yanxia Chen, Jiali Qian, Guozhuang Chen, Kun Wang

“…This study aimed to explore the potential impacts and underlying neuroelectronic mechanisms of a single session of aerobic exercise at varying intensities on general and food-related inhibitory functions among young adult males with obesity. <b>Design</b>: A within-subject design comprising three sessions (control, low-intensity exercise, moderate-intensity exercise) × three picture types (high-calorie food, low-calorie food, neutral picture) was employed. …”
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Qualitative Insights on Barriers to Receiving a Second Dose of Measles-Containing Vaccine (MCV2), Oromia Region of Ethiopia by Kalkidan Solomon, Brooke N. Aksnes, Abyot Bekele Woyessa, Chala Gari Sadi, Almea M. Matanock, Monica P. Shah, Paulos Samuel, Bekana Tolera, Birhanu Kenate, Abebe Bekele, Tesfaye Deti, Getachew Wako, Amsalu Shiferaw, Yohannes Lakew Tefera, Melkamu Ayalew Kokebie, Tatek Bogale Anbessie, Habtamu Teklie Wubie, Aaron Wallace, Ciara E. Sugerman, Mirgissa Kaba

“…In this qualitative study, we explored barriers to the uptake of MCV2 among caregivers, community leaders, and healthcare workers (HCWs). <b>Method:</b> A qualitative study was conducted between mid-April and mid-May 2021. …”
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Safety and efficacy of selective RIPK1 inhibitor SIR1-365 in hospitalized patients with severe COVID-19: A multicenter, randomized, double-blind, phase 1b trial by Norberto Chavez-Tapia, Muneeba Ahsan Sayeed, Shobha Luxmi, Douglas J. Kasper, Fenchao Xue, Yang Shen, Weiliang Fan, Wei Yuan, Bin Du

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Association of TNF-α gene promoter polymorphism with primary open-angle glaucoma by A.V. Shevchenko, V.F. Prokof’ev, V.I. Konenkov, A.V. Eremina, A.N. Trunov, V.V. Chernykh

“…<p> <b>A.V. Shevchenko¹, V.F. Prokof’ev¹, V.I. …”
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Long-term outcomes combined minimally invasive laser surgical technique for local rhegmatogenous retinal detachment by A.V. Doga, D.O. Shkvorchenko, L.A. Kryl, M.R. Taevere, D.A. Buryakov

“…<p> <b>A.V.&nbsp;Doga, D.O.&nbsp;Shkvorchenko, L.A.&nbsp;Kryl, M.R.…”
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The efficacy of sinustrabeculectomy in the modern clinical practice by A.V. Antonova, V.P. Nikolaenko, V.V. Brzheskiy, A.Ya. Vuks

“…</p> <p> <b>Conclusion</b>: a statistically significant IOP decrease from the baseline was achieved in all patients even after the "complete failure" of the surgical treatment at all endpoints of the study. …”
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Mechanical Ventilator-Associated Pneumonia in the COVID-19 Pandemic Era: A Critical Challenge in the Intensive Care Units by Mircea Stoian, Adina Andone, Sergiu Rareș Bândilă, Danusia Onișor, Sergiu Ștefan Laszlo, Gabriela Lupu, Alina Danielescu, Dragoș-Florin Baba, Anca Meda Văsieșiu, Andrei Manea, Adina Stoian

“…This study compares patients with VAP in COVID-19 and non-COVID-19 groups, examining the clinical progression, duration of ventilation and hospitalization, mortality, pathogen distribution, and the emergence of multidrug-resistant strains. <b>Results:</b> A length of stay in the ICU exceeding 11.5 days was associated with the development of multidrug-resistant (MDR) infections (AUC: 0.708, <i>p</i> < 0.001). …”
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Epidemiological analysis primary open-angle glaucoma incidence and prevalence in Russia by A.B. Movsisyan, A.V. Kuroyedov, M.A. Arkharov, V.V. Prokhorenko, I.A.Chepurnov

“…<p> <b>A.B. Movsisyan^1,2, A.V. Kuroedov^1,3, M.A. …”
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Exploring the Potential of Malvidin and Echiodinin as Probable Antileishmanial Agents Through In Silico Analysis and In Vitro Efficacy by Luis Daniel Goyzueta-Mamani, Daniela Pagliara Lage, Haruna Luz Barazorda-Ccahuana, Margot Paco-Chipana, Mayron Antonio Candia-Puma, Gonzalo Davila-Del-Carpio, Alexsandro Sobreira Galdino, Ricardo Andrez Machado-de-Avila, Rodolfo Cordeiro Giunchetti, Edward L. D’Antonio, Eduardo Antonio Ferraz Coelho, Miguel Angel Chávez-Fumagalli

“…In this study, the in vitro potential of malvidin and echioidinin is examined as antileishmanial agents against <i>L. amazonensis</i>, <i>L. braziliensis</i>, and <i>L. infantum</i>, comparing their effects to amphotericin B (AmpB), a standard drug. Malvidin demonstrated greater potency than echioidinin across all parasite stages and species. …”
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Surgical repair of conjunctival defects: perspectives and limitations by M.B. Gushсhina, A.V. Tereshchenko, A.V. Gushchin, D.S. Afanasyeva

“…</i> </p> <p> <i><b>Patients and Methods:</b> a retrospective analysis of the outcomes of surgical repair of conjunctival defects using full-thickness and/or split-thickness autografts of the labial or cheek mucosa in 27 patients. …”
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Evidence Gaps and Lessons in the Early Detection of Atrial Fibrillation: A Prospective Study in a Primary Care Setting (PREFATE Study) by Josep L. Clua-Espuny, Alba Hernández-Pinilla, Delicia Gentille-Lorente, Eulàlia Muria-Subirats, Teresa Forcadell-Arenas, Cinta de Diego-Cabanes, Domingo Ribas-Seguí, Anna Diaz-Vilarasau, Cristina Molins-Rojas, Meritxell Palleja-Millan, Eva M. Satué-Gracia, Francisco Martín-Luján

“…Statistical analyses examined relationships between AF and clinical, echocardiographic, and biomarker variables. <b>Results:</b> A total of 18 cases (12.08%) were identified as positive for possible DDAF using FibriCheck^® and 13 new cases of AF were diagnosed during follow-up, with a 71.4-fold higher probability of confirming AF in FibriCheck^®-positive individuals than in FibriCheck^®-negative individuals, resulting in a post-test odds of 87.7%. …”
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Effectiveness and tolerability of the combined use of anti-VEGF agents in clinical practice by A.V. Kuroyedov, O.V. Gapon’ko, V.V. Gorodnichiy, S.V. Diordiychuk, I.V. Kondrakova, N.M. Sol’nov, N.E. Fomin

“…<p> <b>A.V. Kuroyedov^1,2, O.V.&nbsp;Gapon’ko^1,2, V.V. …”
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Interventions by Cardiovascular Drugs Against Aircraft Noise-Induced Cardiovascular Oxidative Stress and Damage by Marin Kuntić, Ivana Kuntić, Jiayin Zheng, Leonardo Nardi, Matthias Oelze, Arijan Valar, Dominika Mihaliková, Lea Strohm, Henning Ubbens, Qi Tang, Liyu Zhang, Guilherme Horta, Paul Stamm, Omar Hahad, Dilja Krueger-Burg, Huige Li, Sebastian Steven, Adrian Gericke, Michael J. Schmeisser, Thomas Münzel, Andreas Daiber

“…Using our established mouse exposure model, we applied mean sound pressure levels of 72 dB(A) for 4 d. C57BL/6 mice were treated with the beta-blocker propranolol (15 mg/kg/d s.c. for 5 d) or the alpha-blocker phenoxybenzamine (1.5 mg/kg/d s.c. for 5 d) and noise-exposed for the last 4 d of the drug administration. …”
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The Pathogenic Role of Expanded CD8⁺CD28^null Angiogenic T Cells in ANCA-Associated Vasculitis by Haomiao Shen, Jinlin Miao, Haoyang Sun, Kui Zhang, Renli Liu, Zichao Li, Leyang Zhang, Peiyan Zhang, Jiawei Wang, Bei Zhang, Longyu Chen, Zhaohui Zheng, Ping Zhu

“…This study aims to investigate the characteristics and potential roles of CD8⁺CD28^null Tang in patients with ANCA-associated vasculitis (AAV). <b>Methods:</b> A cohort of AAV patients and matched healthy controls (HCs) were analyzed. …”
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